XLOC_025686 (dnm2a)


Basic Information

Item Value
gene id XLOC_025686
gene name dnm2a
gene type coding
species zebrafish (Danio rerio)
category of species model fish

Chromosome Information

Item Value
chromosome id NC_007114.7
NCBI id CM002887.2
chromosome length 62628489
location 47130912 ~ 47213115 (+)
genome version GRCz11_2017_zebrafish_Genome

Sequence

>TCONS_00050556
ACGAATGATTGATCCTCTGATCACAGCACGTATTACAACACATGCGCGTCTTCTGTCAGTCAGCGAGTGTTTTACGCGCCGTTTGCCTTTGACAGACCGTTCTGGAAGCGTTTGAAGGGTGGAAACTGAACACTTGAAAGTAACCCGAGCGCCCTGCTGCTGCGAGCCCGTTCCTGCGCGCTGAGAGACGGCCAGAAACCATGGGCAACCGGGGGATGGAGGAATTGATCCCCCTGATCAATAAACTCCAAGATGCTTTCAGCTCCATTGGCCAAAGTTGTAACCTGGATCTGCCGCAGATAGCAGTTGTCGGAGGACAGAGCGCCGGAAAAAGCTCCGTGCTGGAAAATTTCGTCGGCAGGGATTTCCTTCCGCGAGGCTCAGGCATCGTCACCCGCAGGCCTCTCATTCTGCAGCTAGTAAACAACAAAGCCGAATATGCAGAGTTCCTACACTGCAAAGGGAGGAAGTTCGTGGACTTTGATGAAGTCCGGCAGGAGATTGAAGCAGAAACCGACAGGATTACAGGCTCCAATAAGGGCATCTCTCCTATCCCCATCAACCTGAGAGTCTACTCTCCTAACGTATTGAATCTGACACTCATCGATTTGCCTGGGATGACGAAGGTGGCAGTGGGCGACCAGCCGCCTGACATCGAGCACCAGATTCGGGACATGATAATGCAGTTTATCACCAGGGAGAGCTGTCTAATCCTTGCCGTCACCCCAGCCAACATGGACTTGGCCAATTCGGATGCCCTCAAGGTGGCGAAAGAAGTGGACCCTCAAGGACTGCGTACCATTGGTGTAATCACTAAACTGGATTTAATGGATGAGGGTACAGATGCCCGGGATATCCTGGAAAACAAACTTTTACCACTTCGTAGAGGTTATATCGGTGTAGTGAACCGGAGTCAGAAAGACATTGATGGCCGTAAGGACATTCGTGCTGCGCTGGCAGCAGAAAGGAAGTTTTTCCTGTCCCACCCTAGTTACAGACATATGGCTGAAAGGATGGGAACGCCACACCTGCAAAAAGCCCTCAACCAGcaATTGACCAACCACATCCGGGACACACTTCCCGGCTTGCGGAGCAAACTCCAGTCTCAGCTTCTCTCTCTAGAAAAAGAAGTGGAAGAGTATAAGAACTTCCGCCCAGATGACCCTACTCGAAAGACCAAGGCCCTGCTGCAGATGGTCCAGCAATTTGGTGTGGACTTTGAGAAGTGCATTGAGGGATCCGGAGATCAGGTGGACACTGCAGAGCTGTCTGGAGGTGCCAGGATTAACCGAATCTTTCATGAGCGCTTCCCCTTTGAGCTGGTCAAGATCGTGTTTGATGAAAAGGAGCTCCGGAGAGAAATCAGTCACGCCATTAAGAACGTCCATGGTGTCAGAACTGGGCTGTTCACTCCAGATCTGGCGTTTGAAGCCATCGTGAAAAAGCAGATCATTAAGCTGAAAGAGCCCTGTCTGAAATGTATCGATCTGGTTATTCAGGAGCTCATCAACACATTCAGGCAGTGCACCAACAAGTTAAGCTCGTACCCTAGACTCCGAGAAGAGACGGAGAGGATCGTCACTACTTACGTCAGAGAGAGAGAAGGGAAGACCAAGGACCAGGTTCTTTTGCTGATTGACACTGAGCTGTCATACATCAACACCAACCACGAGGACTTCATTGGATTTGCAAATGCACAGCAAAGGAATATCGTCAACAAGAAGAGGGCCATTCCCAACCAGGTGATCCGTAAAGGCTGGTTAACCCTGAACATCAGCATCATGAAAGGAGGTTCAAAGGAGTACTGGTTCGTCCTGACTGCCGAATCGCTGTCCTGGTACAAAGACGAGGAGGAAAAAGAGAAGAAATACATGCTTCCTCTGGATAACCTGAAGCTCAGAGACGTGGAGAAAGGCTTCATGTCCACTAAGCACATTTTTGCAATCTTCAACACTGAGCAAAGGAATGTGTATAAGGACTTGCGTCAGATCGAGCTGGCCTGTGACTCGCAGGAGGACATGGATAGTTGGAAAGCCTCTTTTCTCAGAGCAGGCGTTTACCCTGAGAAAGATCAGgtgGAGTCAGAAGAGGCAGCCCCAGCCGACAGCTTCTCCATGGACCCTCAGTTGGAAAGACAGGTCGAGACCATCCGTAACCTGGTGGACTCCTATATTGGAATCGTCAACAAAACCATCAGAGACCTCATGCCCAAGACTATCATGCATCTCATGATCAACAGCGCTAAAGACTTCATCCACTCAGAGCTGCTGGCGTACCTGTACTCGTCTGGAGATCAGAACAGTCTGATGGAGGAGTCTGCAGACCAGGCCCAGCGCAGAGACGAGATGCTGAGGATGTACCATGCCATCAAAGAGGCACTCAGCATCATCGGTGACATCAGCACCAGCACCATCTCCACACCTGTGCCACCACCCGTCAACGACAGCTGGATACCTGAAACCAGGTGAGGATGCCAACCACATCCTGACATGCGTGCCAAAGAATAGGATTTGTTTTACAATACCTTTCTATATGTTCATCATAGACTGAATAAAAGAGATTGGCGATATGG
>TCONS_00050557
ACGAATGATTGATCCTCTGATCACAGCACGTATTACAACACATGCGCGTCTTCTGTCAGTCAGCGAGTGTTTTACGCGCCGTTTGCCTTTGACAGACCGTTCTGGAAGCGTTTGAAGGGTGGAAACTGAACACTTGAAAGTAACCCGAGCGCCCTGCTGCTGCGAGCCCGTTCCTGCGCGCTGAGAGACGGCCAGAAACCATGGGCAACCGGGGGATGGAGGAATTGATCCCCCTGATCAATAAACTCCAAGATGCTTTCAGCTCCATTGGCCAAAGTTGTAACCTGGATCTGCCGCAGATAGCAGTTGTCGGAGGACAGAGCGCCGGAAAAAGCTCCGTGCTGGAAAATTTCGTCGGCAGGGATTTCCTTCCGCGAGGCTCAGGCATCGTCACCCGCAGGCCTCTCATTCTGCAGCTAGTAAACAACAAAGCCGAATATGCAGAGTTCCTACACTGCAAAGGGAGGAAGTTCGTGGACTTTGATGAAGTCCGGCAGGAGATTGAAGCAGAAACCGACAGGATTACAGGCTCCAATAAGGGCATCTCTCCTATCCCCATCAACCTGAGAGTCTACTCTCCTAACGTATTGAATCTGACACTCATCGATTTGCCTGGGATGACGAAGGTGGCAGTGGGCGACCAGCCGCCTGACATCGAGCACCAGATTCGGGACATGATAATGCAGTTTATCACCAGGGAGAGCTGTCTAATCCTTGCCGTCACCCCAGCCAACATGGACTTGGCCAATTCGGATGCCCTCAAGGTGGCGAAAGAAGTGGACCCTCAAGGACTGCGTACCATTGGTGTAATCACTAAACTGGATTTAATGGATGAGGGTACAGATGCCCGGGATATCCTGGAAAACAAACTTTTACCACTTCGTAGAGGTTATATCGGTGTAGTGAACCGGAGTCAGAAAGACATTGATGGCCGTAAGGACATTCGTGCTGCGCTGGCAGCAGAAAGGAAGTTTTTCCTGTCCCACCCTAGTTACAGACATATGGCTGAAAGGATGGGAACGCCACACCTGCAAAAAGCCCTCAACCAGcaATTGACCAACCACATCCGGGACACACTTCCCGGCTTGCGGAGCAAACTCCAGTCTCAGCTTCTCTCTCTAGAAAAAGAAGTGGAAGAGTATAAGAACTTCCGCCCAGATGACCCTACTCGAAAGACCAAGGCCCTGCTGCAGATGGTCCAGCAATTTGGTGTGGACTTTGAGAAGTGCATTGAGGGATCCGGAGATCAGGTGGACACTGCAGAGCTGTCTGGAGGTGCCAGGATTAACCGAATCTTTCATGAGCGCTTCCCCTTTGAGCTGGTCAAGATCGTGTTTGATGAAAAGGAGCTCCGGAGAGAAATCAGTCACGCCATTAAGAACGTCCATGGTGTCAGAACTGGGCTGTTCACTCCAGATCTGGCGTTTGAAGCCATCGTGAAAAAGCAGATCATTAAGCTGAAAGAGCCCTGTCTGAAATGTATCGATCTGGTTATTCAGGAGCTCATCAACACATTCAGGCAGTGCACCAACAAGTTAAGCTCGTACCCTAGACTCCGAGAAGAGACGGAGAGGATCGTCACTACTTACGTCAGAGAGAGAGAAGGGAAGACCAAGGACCAGGTTCTTTTGCTGATTGACACTGAGCTGTCATACATCAACACCAACCACGAGGACTTCATTGGATTTGCAAATGCACAGCAAAGGAATATCGTCAACAAGAAGAGGGCCATTCCCAACCAGGTGATCCGTAAAGGCTGGTTAACCCTGAACATCAGCATCATGAAAGGAGGTTCAAAGGAGTACTGGTTCGTCCTGACTGCCGAATCGCTGTCCTGGTACAAAGACGAGGAGGAAAAAGAGAAGAAATACATGCTTCCTCTGGATAACCTGAAGCTCAGAGACGTGGAGAAAGGCTTCATGTCCACTAAGCACATTTTTGCAATCTTCAACACTGAGCAAAGGAATGTGTATAAGGACTTGCGTCAGATCGAGCTGGCCTGTGACTCGCAGGAGGACATGGATAGTTGGAAAGCCTCTTTTCTCAGAGCAGGCGTTTACCCTGAGAAAGATCAGgtgGAGTCAGAAGAGGCAGCCCCAGCCGACAGCTTCTCCATGGACCCTCAGTTGGAAAGACAGGTCGAGACCATCCGTAACCTGGTGGACTCCTATATTGGAATCGTCAACAAAACCATCAGAGACCTCATGCCCAAGACTATCATGCATCTCATGATCAACAGCGCTAAAGACTTCATCCACTCAGAGCTGCTGGCGTACCTGTACTCGTCTGGAGATCAGAACAGTCTGATGGAGGAGTCTGCAGACCAGGCCCAGCGCAGAGACGAGATGCTGAGGATGTACCATGCCATCAAAGAGGCACTCAGCATCATCGGTGACATCAGCACCAGCACCATCTCCACACCTGTGCCACCACCCGTCAACGACAGCTGGATACCTGAAACCAGtcccacCCCTCAGCGCAGACCGCCTACATCTGCACCGCCCCCCAACAGGCCTCCAGCAGTGAGAGGTCCAACCCCAGGCCCTCCTCCTCTTAACCCCACCCCCTCATTTGCAGCCCCACCCATCCCCTCTCGGCCAGGTCAGCCCATGAATGCCTTTGGCAACAGCAGCCAGGATCCTTTCAGCGCACCTCCACAGATCCCTTCTCGCCCCGCACGCATCCCACCAGGCGTCCCCAGCAGAAGACCCCCTGGCGCACCCAACCGGCCCACCATTATCCGCCCCGCTGAGCCCTCCCTGCTAGACTAGACCCGAGCGCTGGCCACCATAGTGTGCTGGGCTGACAGAAACACAAACAGAGAAAGGAATGGCTGGAGAACTGCACTGAAACATGTGCACGTGTGTCCACACAATACAGCCTGACCCATAGACATCCAAAATAAGTGTCCTCTGACCAGCGCTGCTAATCGCATCTTAAATCCCAGAGCTCAAAAATTAAGCACATAAATATTCaaatacatttgttattattattattattgctgttgtttgttttgttcaactATAGTGTGAACTAAAGGGTGTAGTGGCCTCCAACTTTCAGTTATTTTCATTACTCACATTAATCAGGTGACCACCAGGGGGTGTCCTACTCAGCTCGTGTAGACGAACCAACGGTAGACTTGACTAATGGGTTAAGATGTAAACAAGCACTGTGCAAGCTAGTTCAACTGGCCTGTCTTCCTGTTCTTGGGTGGTTGAAGACTCTTTCTTGTTATAGACACACTTCTTCATATGTGGGTTTTGGTTTTCATC
>TCONS_00050558
ATGGGCAACCGGGGGATGGAGGAATTGATCCCCCTGATCAATAAACTCCAAGATGCTTTCAGCTCCATTGGCCAAAGTTGTAACCTGGATCTGCCGCAGATAGCAGTTGTCGGAGGACAGAGCGCCGGAAAAAGCTCCGTGCTGGAAAATTTCGTCGGCAGGGATTTCCTTCCGCGAGGCTCAGGCATCGTCACCCGCAGGCCTCTCATTCTGCAGCTAGTAAACAACAAAGCCGAATATGCAGAGTTCCTACACTGCAAAGGGAGGAAGTTCGTGGACTTTGATGAAGTCCGGCAGGAGATTGAAGCAGAAACCGACAGGATTACAGGCTCCAATAAGGGCATCTCTCCTATCCCCATCAACCTGAGAGTCTACTCTCCTAACGTATTGAATCTGACACTCATCGATTTGCCTGGGATGACGAAGGTGGCAGTGGGCGACCAGCCGCCTGACATCGAGCACCAGATTCGGGACATGATAATGCAGTTTATCACCAGGGAGAGCTGTCTAATCCTTGCCGTCACCCCAGCCAACATGGACTTGGCCAATTCGGATGCCCTCAAGGTGGCGAAAGAAGTGGACCCTCAAGGACTGCGTACCATTGGTGTAATCACTAAACTGGATTTAATGGATGAGGGTACAGATGCCCGGGATATCCTGGAAAACAAACTTTTACCACTTCGTAGAGGTTATATCGGTGTAGTGAACCGGAGTCAGAAAGACATTGATGGCCGTAAGGACATTCGTGCTGCGCTGGCAGCAGAAAGGAAGTTTTTCCTGTCCCACCCTAGTTACAGACATATGGCTGAAAGGATGGGAACGCCACACCTGCAAAAAGCCCTCAACCAGcaATTGACCAACCACATCCGGGACACACTTCCCGGCTTGCGGAGCAAACTCCAGTCTCAGCTTCTCTCTCTAGAAAAAGAAGTGGAAGAGTATAAGAACTTCCGCCCAGATGACCCTACTCGAAAGACCAAGGCCCTGCTGCAGATGGTCCAGCAATTTGGTGTGGACTTTGAGAAGTGCATTGAGGGATCCGGAGATCAGGTGGACACTGCAGAGCTGTCTGGAGGTGCCAGGATTAACCGAATCTTTCATGAGCGCTTCCCCTTTGAGCTGGTCAAGATCGTGTTTGATGAAAAGGAGCTCCGGAGAGAAATCAGTCACGCCATTAAGAACGTCCATGGTGTCAGAACTGGGCTGTTCACTCCAGATCTGGCGTTTGAAGCCATCGTGAAAAAGCAGATCATTAAGCTGAAAGAGCCCTGTCTGAAATGTATCGATCTGGTTATTCAGGAGCTCATCAACACATTCAGGCAGTGCACCAACAAGTTAAGCTCGTACCCTAGACTCCGAGAAGAGACGGAGAGGATCGTCACTACTTACGTCAGAGAGAGAGAAGGGAAGACCAAGGACCAGGTTCTTTTGCTGATTGACACTGAGCTGTCATACATCAACACCAACCACGAGGACTTCATTGGATTTGCAAATGCACAGCAAAGGAATATCGTCAACAAGAAGAGGGCCATTCCCAACCAGGGTGAAATCCTGGTGATCCGTAAAGGCTGGTTAACCCTGAACATCAGCATCATGAAAGGAGGTTCAAAGGAGTACTGGTTCGTCCTGACTGCCGAATCGCTGTCCTGGTACAAAGACGAGGAGGAAAAAGAGAAGAAATACATGCTTCCTCTGGATAACCTGAAGCTCAGAGACGTGGAGAAAGGCTTCATGTCCACTAAGCACATTTTTGCAATCTTCAACACTGAGCAAAGGAATGTGTATAAGGACTTGCGTCAGATCGAGCTGGCCTGTGACTCGCAGGAGGACATGGATAGTTGGAAAGCCTCTTTTCTCAGAGCAGGCGTTTACCCTGAGAAAGATCAGgtgGAGTCAGAAGAGGCAGCCCCAGCCGACAGCTTCTCCATGGACCCTCAGTTGGAAAGACAGGTCGAGACCATCCGTAACCTGGTGGACTCCTATATTGGAATCGTCAACAAAACCATCAGAGACCTCATGCCCAAGACTATCATGCATCTCATGATCAACAGCGCTAAAGACTTCATCCACTCAGAGCTGCTGGCGTACCTGTACTCGTCTGGAGATCAGAACAGTCTGATGGAGGAGTCTGCAGACCAGGCCCAGCGCAGAGACGAGATGCTGAGGATGTACCATGCCATCAAAGAGGCACTCAGCATCATCGGTGACATCAGCACCAGCACCATCTCCACACCTGTGCCACCACCCGTCAACGACAGCTGGATACCTGAAACCAGtcccacCCCTCAGCGCAGACCGCCTACATCTGCACCGCCCCCCAACAGGCCTCCAGCAGTGAGAGGTCCAACCCCAGGCCCTCCTCCTCTTAACCCCACCCCCTCATTTGCAGCCCCACCCATCCCCTCTCGGCCAGGTCAGCCCATGAATGCCTTTGGCAACAGCAGCCAGGATCCTTTCAGCGCACCTCCACAGATCCCTTCTCGCCCCGCACGCATCCCACCAGGCGTCCCCAGCAGAAGACCCCCTGGCGCACCCAACCGGCCCACCATTATCCGCCCCGCTGAGCCCTCCCTGCTAGACTAG
>TCONS_00052370
AACTGGGCTGTTCACTCCAGATCTGGCGTTTGAAGCCATCGTGAAAAAGCAGATCATTAAGCTGAAAGAGCCCTGTCTGAAATGTATCGATCTGGTTATTCAGGAGCTCATCAACACATTCAGGCAGTGCACCAACAAGAACGGGGTTGTTCACCCCTGACCTGGCCTTTGAGACTATAGTGAAAAAACAGATCCACAAACTGAAAGAGCCCAGCCTGAAATGCGTGGACCTGGTGGTGTCCGAACTCACCACTGTCGTCAGGAAAAGCTCTAAGAAGTTAAGCTCGTACCCTAGACTCCGAGAAGAGACGGAGAGGATCGTCACTACTTACGTCAGAGAGAGAGAAGGGAAGACCAAGGACCAGGTTCTTTTGCTGATTGACACTGAGCTGTCATACATCAACACCAACCACGAGGACTTCATTGGATTTGCAAATGCACAGCAAAGGAATATCGTCAACAAGAAGAGGGCCATTCCCAACCAGGTGATCCGTAAAGGCTGGTTAACCCTGAACATCAGCATCATGAAAGGAGGTTCAAAGGAGTACTGGTTCGTCCTGACTGCCGAATCGCTGTCCTGGTACAAAGACGAGGAGGAAAAAGAGAAGAAATACATGCTTCCTCTGGATAACCTGAAG

Function

symbol description
dnm2a Predicted to enable GTPase activity and microtubule binding activity. Acts upstream of or within several processes, including chordate embryonic development; convergent extension; and somite development. Predicted to be located in cytoskeleton. Predicted to be active in several cellular components, including microtubule; plasma membrane; and synapse. Is expressed in several structures, including central nervous system; liver; otic vesicle; paraxial mesoderm; and pericardial region. Human ortholog(s) of this gene implicated in Charcot-Marie-Tooth disease dominant intermediate B; centronuclear myopathy 1; and lethal congenital contracture syndrome. Orthologous to human DNM2 (dynamin 2).

GO:

id name namespace
GO:0006897 endocytosis biological_process
GO:0003374 dynamin family protein polymerization involved in mitochondrial fission biological_process
GO:0043009 chordate embryonic development biological_process
GO:0098884 postsynaptic neurotransmitter receptor internalization biological_process
GO:0016185 synaptic vesicle budding from presynaptic endocytic zone membrane biological_process
GO:0048285 organelle fission biological_process
GO:0031623 receptor internalization biological_process
GO:0061025 membrane fusion biological_process
GO:0061053 somite development biological_process
GO:0061061 muscle structure development biological_process
GO:0050803 regulation of synapse structure or activity biological_process
GO:0060026 convergent extension biological_process
GO:0000266 mitochondrial fission biological_process
GO:0098844 postsynaptic endocytic zone membrane cellular_component
GO:0030424 axon cellular_component
GO:0005874 microtubule cellular_component
GO:0045202 synapse cellular_component
GO:0005886 plasma membrane cellular_component
GO:0015630 microtubule cytoskeleton cellular_component
GO:0045211 postsynaptic membrane cellular_component
GO:0031410 cytoplasmic vesicle cellular_component
GO:0031966 mitochondrial membrane cellular_component
GO:0014069 postsynaptic density cellular_component
GO:0043197 dendritic spine cellular_component
GO:0044327 dendritic spine head cellular_component
GO:0016020 membrane cellular_component
GO:0005737 cytoplasm cellular_component
GO:0003924 GTPase activity molecular_function
GO:0005525 GTP binding molecular_function
GO:0000166 nucleotide binding molecular_function
GO:0008017 microtubule binding molecular_function

KEGG: NA

ZFIN:

id description
ZDB-GENE-050913-84 Predicted to enable GTPase activity and microtubule binding activity. Acts upstream of or within several processes, including chordate embryonic development; convergent extension; and somite development. Predicted to be located in cytoskeleton. Predicted to be active in several cellular components, including microtubule; plasma membrane; and synapse. Is expressed in several structures, including central nervous system; liver; otic vesicle; paraxial mesoderm; and pericardial region. Human ortholog(s) of this gene implicated in Charcot-Marie-Tooth disease dominant intermediate B; centronuclear myopathy 1; and lethal congenital contracture syndrome. Orthologous to human DNM2 (dynamin 2).

Ensembl:

ensembl_id ENSDARG00000069937

RNA

RNA id representative length rna type GC content exon number start site end site
TCONS_00050556 False 2572 mRNA 0.50 18 47130912 47205728
TCONS_00050557 False 3278 mRNA 0.51 20 47130912 47213115
TCONS_00050558 False 2583 mRNA 0.52 21 47131112 47212608
TCONS_00052370 True 638 lncRNA 0.48 7 47175094 47198612

Neighbor

gene id symbol gene type direction distance location
XLOC_025685 NA coding upstream 21439 47107770 ~ 47109473 (+)
XLOC_025684 NA coding upstream 292274 46834857 ~ 46838638 (+)
XLOC_025683 NA coding upstream 327865 46798512 ~ 46803047 (+)
XLOC_025682 prkcsh coding upstream 335129 46762703 ~ 46795783 (+)
XLOC_025680 pde4a coding upstream 376182 46628885 ~ 46754730 (+)
XLOC_025687 tnfsf14 coding downstream 32649 47245764 ~ 47258444 (+)
XLOC_025688 ppap2d coding downstream 109379 47322494 ~ 47387377 (+)
XLOC_025689 NA coding downstream 182420 47395535 ~ 47409399 (+)
XLOC_025690 AL928740.1 coding downstream 247373 47460488 ~ 47460603 (+)
XLOC_025691 NA coding downstream 281407 47494522 ~ 47498343 (+)
XLOC_025429 BX649540.1 misc upstream 16881876 30248739 ~ 30249036 (+)
XLOC_025678 NA non-coding upstream 585431 46545014 ~ 46545481 (+)
XLOC_025668 dre-mir-2195 non-coding upstream 1495726 45635077 ~ 45635186 (+)
XLOC_025693 NA non-coding downstream 827223 48040338 ~ 48041913 (+)
XLOC_025697 NA non-coding downstream 1225951 48439066 ~ 48442896 (+)

Expression


Co-expression Network