Item | Value |
---|---|
gene id | XLOC_002573 |
gene name | nrg1 |
gene type | coding |
species | zebrafish (Danio rerio) |
category of species | model fish |
Item | Value |
---|---|
chromosome id | NC_007121.7 |
NCBI id | CM002894.2 |
chromosome length | 45420867 |
location | 7284121 ~ 7472359 (-) |
genome version | GRCz11_2017_zebrafish_Genome |
symbol | description |
---|---|
nrg1 | Predicted to enable chemorepellent activity and protein tyrosine kinase activator activity. Acts upstream of or within several processes, including enteric nervous system development; fin regeneration; and neurogenesis. Predicted to be located in membrane. Predicted to be integral component of membrane. Predicted to be active in extracellular space. Is expressed in gut; heart; nervous system; and somite. Human ortholog(s) of this gene implicated in several diseases, including bipolar disorder; cerebral malaria; dementia; middle cerebral artery infarction; and psychotic disorder (multiple). Orthologous to human NRG1 (neuregulin 1). |
id | name | namespace |
---|---|---|
GO:0048484 | enteric nervous system development | biological_process |
GO:0001755 | neural crest cell migration | biological_process |
GO:0030154 | cell differentiation | biological_process |
GO:0048513 | animal organ development | biological_process |
GO:0035556 | intracellular signal transduction | biological_process |
GO:0060959 | cardiac neuron development | biological_process |
GO:0036135 | Schwann cell migration | biological_process |
GO:0003222 | ventricular trabecula myocardium morphogenesis | biological_process |
GO:0031101 | fin regeneration | biological_process |
GO:0014044 | Schwann cell development | biological_process |
GO:0007399 | nervous system development | biological_process |
GO:0007422 | peripheral nervous system development | biological_process |
GO:0048699 | generation of neurons | biological_process |
GO:0021755 | eurydendroid cell differentiation | biological_process |
GO:0007171 | activation of transmembrane receptor protein tyrosine kinase activity | biological_process |
GO:0021778 | oligodendrocyte cell fate specification | biological_process |
GO:0005615 | extracellular space | cellular_component |
GO:0016020 | membrane | cellular_component |
GO:0016021 | integral component of membrane | cellular_component |
GO:0005102 | signaling receptor binding | molecular_function |
GO:0045499 | chemorepellent activity | molecular_function |
GO:0030296 | protein tyrosine kinase activator activity | molecular_function |
id | description |
---|---|
ko04012 | ErbB signaling pathway |
ko05014 | Amyotrophic lateral sclerosis |
ko01521 | EGFR tyrosine kinase inhibitor resistance |
ko04052 | Cytokines and growth factors |
ko00536 | Glycosaminoglycan binding proteins |
id | description |
---|---|
ZDB-GENE-050302-113 | Predicted to enable chemorepellent activity and protein tyrosine kinase activator activity. Acts upstream of or within several processes, including enteric nervous system development; fin regeneration; and neurogenesis. Predicted to be located in membrane. Predicted to be integral component of membrane. Predicted to be active in extracellular space. Is expressed in gut; heart; nervous system; and somite. Human ortholog(s) of this gene implicated in several diseases, including bipolar disorder; cerebral malaria; dementia; middle cerebral artery infarction; and psychotic disorder (multiple). Orthologous to human NRG1 (neuregulin 1). |
ensembl_id | ENSDARG00000104314 |
RNA id | representative | length | rna type | GC content | exon number | start site | end site |
---|---|---|---|---|---|---|---|
TCONS_00004781 | False | 2645 | mRNA | 0.48 | 10 | 7284121 | 7386475 |
TCONS_00004783 | False | 2991 | mRNA | 0.50 | 10 | 7284121 | 7472359 |
TCONS_00004782 | False | 2982 | mRNA | 0.50 | 10 | 7284121 | 7472359 |
TCONS_00004784 | False | 2064 | mRNA | 0.55 | 8 | 7284898 | 7347311 |
TCONS_00004785 | False | 2193 | mRNA | 0.54 | 11 | 7284898 | 7472323 |
TCONS_00004786 | True | 511 | processed_transcript | 0.48 | 4 | 7290947 | 7352110 |
gene id | symbol | gene type | direction | distance | location |
---|---|---|---|---|---|
XLOC_002572 | NA | coding | downstream | 30223 | 7238244 ~ 7253898 (-) |
XLOC_002571 | NA | coding | downstream | 222584 | 7050325 ~ 7061537 (-) |
XLOC_002570 | CABZ01061993.1 | coding | downstream | 274631 | 7009374 ~ 7009490 (-) |
XLOC_002569 | sh2d4a | coding | downstream | 307476 | 6967293 ~ 6976645 (-) |
XLOC_002568 | ppip5k2 | coding | downstream | 416839 | 6781123 ~ 6867282 (-) |
XLOC_002574 | wrn | coding | upstream | 11186 | 7483545 ~ 7555660 (-) |
XLOC_002575 | BX537303.2 | coding | upstream | 39649 | 7512008 ~ 7512123 (-) |
XLOC_002576 | ubxn8 | coding | upstream | 151339 | 7623698 ~ 7636340 (-) |
XLOC_002577 | pcyox1 | coding | upstream | 180825 | 7653184 ~ 7671219 (-) |
XLOC_002578 | gmcl1 | coding | upstream | 201087 | 7673446 ~ 7702029 (-) |
XLOC_002566 | BX511100.4 | non-coding | downstream | 557007 | 6725657 ~ 6727114 (-) |
XLOC_002565 | NA | non-coding | downstream | 588789 | 6693514 ~ 6695332 (-) |
XLOC_002585 | BX294661.1 | non-coding | upstream | 398268 | 7870627 ~ 7892684 (-) |
XLOC_002586 | NA | non-coding | upstream | 411394 | 7883753 ~ 7886040 (-) |
XLOC_002590 | NA | non-coding | upstream | 508760 | 7981119 ~ 7983744 (-) |
XLOC_002602 | NA | non-coding | upstream | 1146359 | 8618718 ~ 8621543 (-) |