XLOC_025813 (notum1a)


Basic Information

Item Value
gene id XLOC_025813
gene name notum1a
gene type coding
species zebrafish (Danio rerio)
category of species model fish

Chromosome Information

Item Value
chromosome id NC_007114.7
NCBI id CM002887.2
chromosome length 62628489
location 57948377 ~ 57979190 (+)
genome version GRCz11_2017_zebrafish_Genome

Sequence

>TCONS_00050689
tttttttatttattttaaaaacaatttacactGAATgacttgtgtttttcttttaatagTCATTAAATAAGAGATCATTAAAAACTTTGTCTTTACATTTAAATTCTCCATACAAAAAAAGCACAATTGGACATTAAACAGCCCAATTTTAAAGCATAAATTCCAAATAATAGATGCATTTACAAAATTACGATAGGCTACTATTAATAAAGTAGTCATGTGCATTATAAGTTCCCTCGACGCCTGTAGATGCTCACGCTATTCTCTCtctatgtatttatatgtaagctattttttccaAAGTATGAGTGTCAAAAGAGACTTATTCTCACTCTATAAATTCGCGTGGATTAGGAAACAGCCATTTCAATGCCAATAAAAGCTACCACATCAAGCAAAATATCGCAGTTCAAAACGACCAAACTAtgggcatttttttttcttcaataaacGAAGAGGACAGGAATCAGTAGTGCGACTGGATCACGCCCCGCCGCACTGCCCTCCACAGCGATTGGCTGAAGGGAAAGAGAGCAGGGTTAAAACCCAGAGCGGTTCAATGCACAGGTGCTACAGCGCAACACAAGAGCCCGAGGAGAGGCTTTAGGTCAGCGCAGGAGAGAACTTGGAGGACTTGTGAATTCTGCTCACCTGTTCTGCCGTGTTGACTCagtgtttgtttgcttttaaatTTTGCCTTGTGGTTCAGAAGATTCTCAGCATCACCTCCGGATTTTTGCGCGATGAAGAGGAGCCTCTGGGTGATGCAGGTCCTCCACTGGGCGGTGATGCTGGCTTTGGTTCAGTGCGGCGCGCTTGGTGCGCGGAGGTTCCGCGGAGGTCGAAACCCGCAGCCGCGGCGAGCGCTGCCCTCCGCTCATTACCGGGACCGCGGAGAGACCACCGAGAGCTTCTCACTGGATTTCACAGCCGTGGAGGAAAACATGGACAACTTCATGACTCAGGTGAAGAACCTGGCGCAGTCCCTCTACCCCTGCTCGGCCCAGAAGCTCGACTACGACATGAAGTTACACTTTCTGGAGAATACATCGGTCACCTGTAACGACGGGACTCCTGCGGGGTACTACCTGAAGGAGTCAAAAGGAAGCAAAAGATGGTTAATATTTCTTGAGGGCGGCTGGTACTGCTTCAACAAAGAGAACTGCGACAGCAGATACGAGACTATGAGGAGACTCATGAGCTCCTCCAAATGGCCACAAACCAAGACAGGCACAGGAATGCTGTCTTCACTCCCAGAGGAAAACCCACACTGGTGGAACGCCAACATGGTCTTCATCCCATATTGTTCAAGCGACGTGTGGAGTGGAGCCTCACCAAAAACAGATCAAAATGACTACGCTTTCATGGGTTCACTGATCATAAAGGAGGTCGTGAAGGATCTGCTCTCCAAAGGTCTGGATAATGCCAAGATCCTGCTGTTAGCTGGAAGCAGTGCGGGCGGCACCGGGGTCTTGCTGAATGTGGACTCGGTGTCAGAGCTTTTGGAAGAACTGGGCCACACCAACATCCAGGTCAGGGGTCTGTCCGACTCAGGCTGGTTTCTGGACAACAAGCAGTACAGATGCACTGACTGTGTGGACACCATCAACTGCGCCCCTACTGAGGTCATCAAGAGAGGAATCAAATATTGGGGTGGTGTGGTTCCTGAGCGATGCAGGCAGGCTTATGAAGGAAAAGAGTGGAACTGcttctttggatataaagtttatcctaccatCAAGCGGCCTGTGTTTATCGTGCAGTGGCTGTTCGATGAGGCTCAGCTCACGGTGGACAACATCCATCTGACGGGACAGCCTGTGCAGGAGGGACAGTGGCGCTACATTCAGAATTTGGGGACTGAGCTGAGGAACACTCTGAAGGACGTCCCTGCAATGTTTGCTCCAGCTTGTCTCTCACACGAATTCATCACAAGAAACTACTGGACCGATGTTCAAGTCAAAGGCACATCTCTACCGCGAGCGCTGCACTGCTGGGACCGCAGTCTACAAGACACCAGCAGAAATAACAAATCGCCCCCCAAAGGCTGTCCCGTGCACTTGATCGACAGCTGCCCGTGGCCTCACTGCAACCCCACATGCCCAACCATCCGGGATCAGTCTACAGGGCAGGAGATGAACGTCATCCAGTTCCTCATGCACATGGGCTTCGATGTCCAGAAGATGGCCCACCAGCAGGGAATGGACCCGAGTAAACTCCTGGGCATGCTCAGCAGTGGCAGCTAA

Function

symbol description
notum1a Predicted to enable palmitoleyl hydrolase activity. Acts upstream of or within GPI anchor release; negative regulation of canonical Wnt signaling pathway; and regionalization. Predicted to be located in extracellular region. Is expressed in several structures, including axis; hindbrain neural keel; midbrain hindbrain boundary; neural plate; and neural tube. Orthologous to human NOTUM (notum, palmitoleoyl-protein carboxylesterase).

GO:

id name namespace
GO:0021532 neural tube patterning biological_process
GO:0030178 negative regulation of Wnt signaling pathway biological_process
GO:1990697 protein depalmitoleylation biological_process
GO:0090090 negative regulation of canonical Wnt signaling pathway biological_process
GO:0009952 anterior/posterior pattern specification biological_process
GO:0006507 GPI anchor release biological_process
GO:0016055 Wnt signaling pathway biological_process
GO:0005576 extracellular region cellular_component
GO:0052689 carboxylic ester hydrolase activity molecular_function
GO:0016787 hydrolase activity molecular_function
GO:1990699 palmitoleyl hydrolase activity molecular_function

KEGG: NA

ZFIN:

id description
ZDB-GENE-120807-2 Predicted to enable palmitoleyl hydrolase activity. Acts upstream of or within GPI anchor release; negative regulation of canonical Wnt signaling pathway; and regionalization. Predicted to be located in extracellular region. Is expressed in several structures, including axis; hindbrain neural keel; midbrain hindbrain boundary; neural plate; and neural tube. Orthologous to human NOTUM (notum, palmitoleoyl-protein carboxylesterase).

Ensembl:

ensembl_id ENSDARG00000031126

RNA

RNA id representative length rna type GC content exon number start site end site
TCONS_00050689 True 2246 mRNA 0.49 11 57948377 57979190

Neighbor

gene id symbol gene type direction distance location
XLOC_025812 cenpx coding upstream 118354 57825938 ~ 57830023 (+)
XLOC_025811 CU571328.1 coding upstream 124830 57820913 ~ 57823547 (+)
XLOC_025810 tmc6a coding upstream 131500 57779673 ~ 57816877 (+)
XLOC_025809 NA coding upstream 179711 57766624 ~ 57768666 (+)
XLOC_025808 CT573423.1 coding upstream 307287 57636374 ~ 57641090 (+)
XLOC_025814 NA coding downstream 2068 57981258 ~ 57986847 (+)
XLOC_025815 myadml2 coding downstream 11884 57991074 ~ 57991985 (+)
XLOC_025816 NA coding downstream 15188 57994378 ~ 57995547 (+)
XLOC_025817 pycr1a coding downstream 18790 57997980 ~ 58006138 (+)
XLOC_025818 si:ch211-256e16.7 coding downstream 113022 58092212 ~ 58097473 (+)
XLOC_025429 BX649540.1 misc upstream 27699341 30248739 ~ 30249036 (+)
XLOC_025806 NA non-coding upstream 467381 57426160 ~ 57480996 (+)
XLOC_025807 NA non-coding upstream 512073 57434261 ~ 57436304 (+)
XLOC_025802 NA non-coding upstream 990819 56949955 ~ 56957558 (+)
XLOC_025822 NA non-coding downstream 208797 58187987 ~ 58192699 (+)
XLOC_025823 NA non-coding downstream 209464 58188654 ~ 58193860 (+)
XLOC_025824 NA non-coding downstream 231185 58210375 ~ 58212686 (+)

Expression


Co-expression Network

Homologous

species gene id symbol gene type chromosome NCBI id location
grasscarp (Ctenopharyngodon idella) CI01000112_02324515_02338662 NOTUM1A, NOTUM coding CI01000112 null 2324389 ~ 2339089 (-)