XLOC_025817 (pycr1a)


Basic Information

Item Value
gene id XLOC_025817
gene name pycr1a
gene type coding
species zebrafish (Danio rerio)
category of species model fish

Chromosome Information

Item Value
chromosome id NC_007114.7
NCBI id CM002887.2
chromosome length 62628489
location 57997980 ~ 58006138 (+)
genome version GRCz11_2017_zebrafish_Genome

Sequence

>TCONS_00050691
CCACACACTCCACTAATGGCAGTTCACAGACAGCgtgaacaacacaacaaacaaacctgaaataaactaaatataagtGAACCAGCTCTTCAGCACATCGTATTTTAGGTCAGAATGAGTGTGGGATTTATCGGAGCTGGTCAGCTGGCGCATGCGCTGGTCAAGGGCTTCACAGCCGCAGGTGTGATCGCCACACACAGGATAACAGCGAGTTCTCCAGACACTGACCTGCCGACGGTCATTGGCCTGAGAAAAATGGGAGCGTTCTTCACCACCAGTAATAAAGAGACCGTGAGCAAGAGTGACGTCCTTTTCCTGGCGGTCAAGCCTCATATCATTCCCTTTGTCCTGGACGAGATCGGCCCAGACATTGAAGACCGCCACCTCATCGTCTCCTGTGCTGCAGGAGTGACCATCAGCTCCATCGAGAAGAAACTGCTGCAGTACCGTTCAGCACCTAAAGTCATTCGCTGCATGACAAACACCCCGGTGGTGGTCCGCGAGGGGGCCACGGTTTACGCCACAGGCACCCATGCGGAGGTGGAGGACGGGAAGCTCCTGGAGCAGCTAATGGCCAGTGTGGGCTACTGCACCGAGGTGGAAGAGGACCTGATTGATGCCGTCACTGGCCTCAGTGGCAGTGGACCAGCCTATGCATTCACAGCGGTTGATGCTCTTGCTGATGGAGGGGTGAAGATGGGATTGCCCAGAAGACTGGCTGTACGACTGGGAGCTCAGGCCCTGCTTggAGCGGCAAAAATGCTCCTTGAGTCAGAGCAACACCCTGGACAGTTAAAGGACAACGTGGCTTCGCCTGGAGGTGCTACAATCCACGCTTTGCATGTGATGGAAAGTGGCGGTTTCCGCAGCCTCCTGATCAATGCTGTGGAGGCTTCGTGCATTAGAACCAGGGAGCTTCAGTATTTGGCAGATCAAGAGAAGATCTCTCCCGCTGCCATCAAGAAGACGACTCTGGACAAAGTGCTCCAGCAGCCGGGGGTGACAGCAGCAGGGGTCGGGGTCCGGACAGGAATCAACCTCTTTAACAGTACAAACCCCAAACACAAGAAAAGCTGAACCCAATTAGCAGAACAACCAACTGACACATAGACAAAACCACTCCAAAGATTTGCAGATCAGATGATAGAACCAAAAATACTTGAAATAGTCTTCATGAACTGGTTAGTGGGAttcacagttgaaaccagaagtttaaatacacaaaacataaccattaaaaaaaaaaagtctgatggttaatcatactaaatgtttactattttaggtccattaggattacctacagtaaatgatttacatttgctaaatgccagaattttttttgagaatttttattaatttctagacggTCAAAAGTTGACACacatttccacattttttttagctttgcttttaaactgtataactttggtcaaatgttttgggaatccttccacaagcttttcacaatagtttgaaggaattttggcccattacTCTTGACAGAAttagtgtaactgagtcagatttgtaggctgtactgcttgcacaagctttttcaactctgcccacaaattttctataggattgagatcagggctttgtgatggccactccaaaacattcactctgttgtccttaaagcacatttgaactaatttggcagtatgcttaggttcatggtctgtttggaagacccatttgtggccgaGTTTTAATTtcttggctgatgtcttgagatgtggcttcagtatttctacataatgttctttcctcatgatgccatctatgttgtgaagtggaccagtccctcctacagcaaaacagccccacaacatgatgctgccgcccccatacttcacagttgggatggtgttcctaggcttgtaagctttacCCATtgttctccaaatgtaacactggttattaaggccaaacagttcaatcagaataacaggacatgtctccaaaatttagtcttttcccagtgtaatttagcaaattgtaatctgccttttttgttgattctggcttgttgattttcccatgttgtcacacaaggaagcagtgtgctTGCGGTTTTCCTTAAAtcctattctacagttgtgcctccaattaactcagaggttgtcaattagccaatcagaaacttccaaacccttgacaccatcatctgagctttttcagaggcagaataatcttattgaatgtaaacttgactttcaagaaaagttataacaatttctcaaaatatctctctcattattctgctattaagcataacagaaacacatttggtAATCCTAACCTAGCtaaaaaaagtttagtcacattaatatctgacttttaaaaaaatgattatgtgcctttttatacaatgcatgtaaatttcctctggtttcaactgtatatattttattctgtGCTCAGATACAATTTTATATTGCGCTTTTAGCTAACGCTAGTTTGGACCAACTTTAAGCAATAATTTCTGTTGATATACACTGTAACCGCTGTAACTGTATTTAATAAATCATGTCTAATCTAGAAA
>TCONS_00050692
CACTAATGGCAGTTCACAGACAGCgtgaacaacacaacaaacaaacctgaaataaactaaatataagtGAACCAGCTCTTCAGCACATCGTATTTTAGGTCAGAATGAGTGTGGGATTTATCGGAGCTGGTCAGCTGGCGCATGCGCTGGTCAAGGGCTTCACAGCCGCAGGTACAgcgacatttacacacactcaccaCTAGAAAGCGCACTGCCACACGATAAAACACAACACTGAGAAATTATTAATCTTCAATTTTtggaaaatgtgtatttatacttGATCtgaaagtgaaataaataagTTTCCAATTGATGTGTGACTTCGTAGgaatacatgaaaaaa
>TCONS_00050693
TGGCAGTTCACAGACAGCgtgaacaacacaacaaacaaacctgaaataaactaaatataagtGAACCAGCTCTTCAGCACATCGTATTTTAGGTCAGAATGAGTGTGGGATTTATCGGAGCTGGTCAGCTGGCGCATGCGCTGGTCAAGGGCTTCACAGCCGCAGGTGTGATCGCCACACACAGGATAACAGCGAGTTCTCCAGACACTGACCTGCCGACGGTCATTGGCCTGAGAAAAATGGGAGCGTTCTTCACCACCAGTAATAAAGAGACCGTGAGCAAGAGTGACGTCCTTTTCCTGGCGGTCAAGCCTCATATCATTCCCTTTGTCCTGGACGAGATCGGCCCAGACATTGAAGACCGCCACCTCATCGTCTCCTGTGCTGCAGGAGTGACCATCAGCTCCATCGAGAAGAAACTGCTGCAGTACCGTTCAGCACCTAAAGTCATTCGCTGCATGACAAACACCCCGGTGGTGGTCCGCGAGGGGGCCACGGTTTACGCCACAGGCACCCATGCGGAGGTGGAGGACGGGAAGCTCCTGGAGCAGCTAATGGCCAGTGTGGGCTACTGCACCGAGGTGGAAGAGGACCTGATTGATGCCGTCACTGGCCTCAGTGGCAGTGGACCAGCCTATGCATTCACAGCGGTTGATGCTCTTGCTGATGGAGGGGTGAAGATGGGATTGCCCAGAAGACTGGCTGTACGACTGGGAGCTCAGGCCCTGCTTggAGCGGCAAAAATGCTCCTTGAGTCAGAGCAACACCCTGGACAGTTAAAGGACAACGTGGCTTCGCCTGGAGGTGCTACAATCCACGCTTTGCATGTGATGGAAAGTGGCGGTTTCCGCAGCCTCCTGATCAATGCTGTGGAGGCTTCGTGCATTAGAACCAGGGAGCTTCAGTATTTGGCAGATCAAGAGAAGATCTCTCCCGCTGCCATCAAGAAGACGACTCTGGACAAAGTGCTCCAGCAGCCGGGGGTGACAGCAGCAGGGGTCGGGGTCCGGACAGGAATCAACCTCTTTAACAGTACAAACCCCAAACACAAGAAAAGCTGAACCCAATTAGCAGAACAACCAACTGACACATAGACAAAACCACTCCAAAGATTTGCAGATCAGATGATAGAACCAAAAATACTTGAAATAGTCTTCATGAACTGGTTAGTGGGAttcacagttgaaaccagaagtttaaatacacaaaacataaccattaaaaaaaaaaagtctgatggttaatcatactaaatgtttactattttaggtccattaggattacctacagtaaatgatttacatttgctaaatgccagaattttttttgagaatttttattaatttctagacggTCAAAAGTTGACACacatttccacattttttttagctttgcttttaaactgtataactttggtcaaatgttttgggaatccttccacaagcttttcacaatagtttgaaggaattttggcccattacTCTTGACAGAAttagtgtaactgagtcagatttgtaggctgtactgcttgcacaagctttttcaactctgcccacaaattttctataggattgagatcagggctttgtgatggccactccaaaacattcactctgttgtccttaaagcacatttgaactaatttggcagtatgcttaggttcatggtctgtttggaagacccatttgtggccgaGTTTTAATTtcttggctgatgtcttgagatgtggcttcagtatttctacataatgttctttcctcatgatgccatctatgttgtgaagtggaccagtccctcctacagcaaaacagccccacaacatgatgctgccgcccccatacttcacagttgggatggtgttcctaggcttgtaagctttacCCATtgttctccaaatgtaacactggttattaaggccaaacagttcaatcagaataacaggacatgtctccaaaatttagtcttttcccagtgtaatttagcaaattgtaatctgccttttttgttgattctggctttgtgctTGCGGTTTTCCTTAAAtcctattctacagttgtgcctccaattaactcagaggttgtcaattagccaatcagaaacttccaaacccttgacaccatcatctgagctttttcagaggcagaataatcttattgaatgtaaacttgactttcaagaaaagttataacaatttctcaaaatatctctctcattattctgctattaagcataacagaaacacatttggtAATCCTAACCTAGCtaaaaaaagtttagtcacattaatatctgacttttaaaaaaatgattatgtgcctttttatacaatgcatgtaaatttcctctggtttcaactgtatatattttattctgtGCTCAGATACAATTTTATATTGCGCTTTTAGCTAACGCTAGTTTGGACCAACTTTAAGCAATAATTTCTGTTGATATACACTGTAACCGCTGTAACTGTATTTAATAAATCATGTCTAATCT

Function

symbol description
pycr1a Predicted to enable pyrroline-5-carboxylate reductase activity. Predicted to be involved in L-proline biosynthetic process. Predicted to act upstream of or within proline biosynthetic process. Used to study autosomal recessive cutis laxa type IIB. Human ortholog(s) of this gene implicated in autosomal recessive cutis laxa type IIB and autosomal recessive cutis laxa type IIIB. Orthologous to human PYCR1 (pyrroline-5-carboxylate reductase 1).

GO:

id name namespace
GO:0055114 oxidation-reduction process biological_process
GO:0055129 L-proline biosynthetic process biological_process
GO:0008652 cellular amino acid biosynthetic process biological_process
GO:0006561 proline biosynthetic process biological_process
GO:0005575 cellular_component cellular_component
GO:0016491 oxidoreductase activity molecular_function
GO:0004735 pyrroline-5-carboxylate reductase activity molecular_function

KEGG: NA

ZFIN:

id description
ZDB-GENE-040426-1675 Predicted to enable pyrroline-5-carboxylate reductase activity. Predicted to be involved in L-proline biosynthetic process. Predicted to act upstream of or within proline biosynthetic process. Used to study autosomal recessive cutis laxa type IIB. Human ortholog(s) of this gene implicated in autosomal recessive cutis laxa type IIB and autosomal recessive cutis laxa type IIIB. Orthologous to human PYCR1 (pyrroline-5-carboxylate reductase 1).

Ensembl:

ensembl_id ENSDARG00000102254

RNA

RNA id representative length rna type GC content exon number start site end site
TCONS_00050691 False 2551 mRNA 0.43 8 57997980 58006138
TCONS_00050692 False 346 processed_transcript 0.40 2 57997990 57998559
TCONS_00050693 True 2496 mRNA 0.43 9 57997996 58006133

Neighbor

gene id symbol gene type direction distance location
XLOC_025816 NA coding upstream 2433 57994378 ~ 57995547 (+)
XLOC_025815 myadml2 coding upstream 5995 57991074 ~ 57991985 (+)
XLOC_025814 NA coding upstream 11133 57981258 ~ 57986847 (+)
XLOC_025813 notum1a coding upstream 18790 57948377 ~ 57979190 (+)
XLOC_025812 cenpx coding upstream 167957 57825938 ~ 57830023 (+)
XLOC_025818 si:ch211-256e16.7 coding downstream 86074 58092212 ~ 58097473 (+)
XLOC_025819 si:ch211-256e16.4 coding downstream 113433 58119571 ~ 58131524 (+)
XLOC_025820 si:ch211-256e16.3 coding downstream 127089 58133227 ~ 58154489 (+)
XLOC_025821 uqcrc2a coding downstream 161150 58167288 ~ 58185030 (+)
XLOC_025822 NA coding downstream 181849 58187987 ~ 58192699 (+)
XLOC_025429 BX649540.1 misc upstream 27748944 30248739 ~ 30249036 (+)
XLOC_025809 NA non-coding upstream 229314 57766624 ~ 57768666 (+)
XLOC_025808 CT573423.1 non-coding upstream 356890 57636374 ~ 57641090 (+)
XLOC_025806 NA non-coding upstream 516984 57426160 ~ 57480996 (+)
XLOC_025823 NA non-coding downstream 182516 58188654 ~ 58193860 (+)
XLOC_025824 NA non-coding downstream 204237 58210375 ~ 58212686 (+)
XLOC_025826 NA non-coding downstream 293900 58300038 ~ 58305878 (+)
XLOC_025827 AL772300.2 non-coding downstream 338724 58344862 ~ 58353587 (+)

Expression


Co-expression Network

Homologous

species gene id symbol gene type chromosome NCBI id location
bowfin (Amia calva) AMCG00013210 pycr1,LOC108236293,LOC103150509,LOC107572052,LOC103465458 coding CM030125.1 CM030125.1 24907121 ~ 24912555 (-)