XLOC_026141 (map2k4a)


Basic Information

Item Value
gene id XLOC_026141
gene name map2k4a
gene type coding
species zebrafish (Danio rerio)
category of species model fish

Chromosome Information

Item Value
chromosome id NC_007114.7
NCBI id CM002887.2
chromosome length 62628489
location 10592597 ~ 10634532 (-)
genome version GRCz11_2017_zebrafish_Genome

Sequence

>TCONS_00051053
AACGCAGCTCCACCCGGCCCAGAGCCAGCACATCACCACCATGAGCAGCATGCAAGtttaaaccATGTGTTCGTTGTTCTTCTCGCCACCAGGGTTTCAGATAAACCTGTCTGGACTTCCTCCAAGTAAACGTAAAGCCCTGAAGTTAAATTTTGCCAATCCTCCAATCAAAACCACTTCCAGAATCACTTCCGGACTTCCTTTCCAGAACCCACACATAGAGCGGCTGCGAACACACAGTATCGAGTCGTCTGGGAAGCTGAAGATCTCAGCGGAGCAGCACTGCGATTTCACAGCAGAAGACCTGAAGGATCTCGGCGAGATCGGCAGAGGAGCGTATGGCTCGGTCAACAAGATGGCGCACAAACCCAGTGGACAAATCATGGCCGTCAAGAGGATTCGTTCAACAGTAGACGAGCGAGAACAGAAGCAGCTGCTGATGGATCTGGATGTGGTCATGAGGAGCAGCGACTGTCCGTACATCGTCCAGTTTTACGGGGCTCTTTTCAGAGAGGGGGATTGCTGGATATGCATGGAGCTCATGTCTACCTCCTTCGACAAATtctacaaatatgtttattcctCTTTAGACGAAGTGATTCCAGAGGAGATTTTAGGGAAAATAACATTAGCTACTGTGAAAGCACTTAACCACTTAAAAGAAAACTTGAAAATTATTCACAGAGACATAAAGCCATCAAATATCCTCCTGGACAGGAAAGGCAACATTAAACTGTGTGATTTTGGCATCAGTGGGCAGCTGGTTGACTCCATCGCCAAAACCAGAGACGCAGGCTGCAGACCGTATATGGCAccgGAGAGGATAGACCCCAGCGCCTCCAGACAGGGTTATGACGTGCGCTCGGATGTGTGGAGTTTGGGCATCACACTGTATGAGCTGGCCACGGGACGCTTCCCCTACCCCAAGTGGAACAGTGTGTTTGACCAGCTGACGCAGGTGGTGAAGGGCGACCCACCACAGCTCAGCAGCTCCGAGGAGAGACAGTTCTCCCCCAAGTTCATCAACTTCGTCAACCTGTGCCTTACAAAGGACGAGTCAAAAAGGCCAAAGTACAAAGAGCTTCTGAAACATGCGTTCATCCAGATGTACGAGGAGCGCTCGGTGGACGTGGCCACTTACGTCTGCAGGATCCTGGATCAGATGCCACCGTCTCCCAGCTCCCCGATGTACGtggactgacacacacacacacacataaacacacgcacacacacacatctgaacgTCCACACGCTGTCTACAGATCTGCTTCATCACACAACTGCAGTATTAAACCAGGAAATGAGCATCTGA
>TCONS_00051054
AGCCCAGCGctgactgctgctgctgctggaagAGTCAAACCCAAATGGCGACGTCCAGCCCAAGCAGTAACCCAGCGTCAGCCTCCAACAACCCAACGCAGCTCCACCCGGCCCAGAGCCAGCACATCACCACCATGAGCAGCATGCAAGGGTTTCAGATAAACCTGTCTGGACTTCCTCCAAGTAAACGTAAAGCCCTGAAGTTAAATTTTGCCAATCCTCCAATCAAAACCACTTCCAGAATCACTTCCGGACTTCCTTTCCAGAACCCACACATAGAGCGGCTGCGAACACACAGTATCGAGTCGTCTGGGAAGCTGAAGATCTCAGCGGAGCAGCACTGCGATTTCACAGCAGAAGACCTGAAGGATCTCGGCGAGATCGGCAGAGGAGCGTATGGCTCGGTCAACAAGATGGCGCACAAACCCAGTGGACAAATCATGGCCGTCAAGAGGATTCGTTCAACAGTAGACGAGCGAGAACAGAAGCAGCTGCTGATGGATCTGGATGTGGTCATGAGGAGCAGCGACTGTCCGTACATCGTCCAGTTTTACGGGGCTCTTTTCAGAGAGGGGGATTGCTGGATATGCATGGAGCTCATGTCTACCTCCTTCGACAAATtctacaaatatgtttattcctCTTTAGACGAAGTGATTCCAGAGGAGATTTTAGGGAAAATAACATTAGCTACTGTGAAAGCACTTAACCACTTAAAAGAAAACTTGAAAATTATTCACAGAGACATAAAGCCATCAAATATCCTCCTGGACAGGAAAGGCAACATTAAACTGTGTGATTTTGGCATCAGTGGGCAGCTGGTTGACTCCATCGCCAAAACCAGAGACGCAGGCTGCAGACCGTATATGGCAccgGAGAGGATAGACCCCAGCGCCTCCAGACAGGGTTATGACGTGCGCTCGGATGTGTGGAGTTTGGGCATCACACTGTATGAGCTGGCCACGGGACGCTTCCCCTACCCCAAGTGGAACAGTGTGTTTGACCAGCTGACGCAGGTGGTGAAGGGCGACCCACCACAGCTCAGCAGCTCCGAGGAGAGACAGTTCTCCCCCAAGTTCATCAACTTCGTCAACCTGTGCCTTACAAAGGACGAGTCAAAAAGGCCAAAGTACAAAGAGCTTCTGAAACATGCGTTCATCCAGATGTACGAGGAGCGCTCGGTGGACGTGGCCACTTACGTCTGCAGGATCCTGGATCAGATGCCACCGTCTCCCAGCTCCCCGATGTACGtggactgacacacacacacacacataaacacacgcacacacacacatctgaacgTCCACACGCTGTCTACAGATCTGCTTCATCACACAACTGCAGTATTAAACCAGGAAATGAGCATCTGA
>TCONS_00051055
CACAGTATCGAGTCGTCTGGGAAGCTGAAGATCTCAGCGGAGCAGCACTGCGATTTCACAGCAGAAGACCTGAAGGATCTCGGCGAGATCGGCAGAGGAGCGTATGGCTCGGTCAACAAGATGGCGCACAAACCCAGTGGACAAATCATGGCCGTCAAGAGGATTCGTTCAACAGTAGACGAGCGAGAACAGAAGCAGCTGCTGATGGATCTGGATGTGGTCATGAGGAGCAGCGACTGTCCGTACATCGTCCAGTTTTACGGGGCTCTTTTCAGAGAGGGGGATTGCTGGATATGCATGGAGCTCATGTCTACCTCCTTCGACAAATtctacaaatatgtttattcctCTTTAGACGAAGTGATTCCAGAGGAGATTTTAGGGAAAATAACATTAGCTACTGTGAAAGCACTTAACCACTTAAAAGAAAACTTGAAAATTATTCACAGAGACATAAAGCCATCAAATATCCTCCTGGACAGGAAAGGCAACATTAAACTGTGTGATTTTGGCATCAGTGGGCAGCTGGTTGACTCCATCGCCAAAACCAGAGACGCAGGCTGCAGACCGTATATGGCAccgGAGAGGATAGACCCCAGCGCCTCCAGACAGGGTTATGACGTGCGCTCGGATGTGTGGAGTTTGGGCATCACACTGTATGAGCTGGCCACGGGACGCTTCCCCTACCCCAAGTGGAACAGTGTGTTTGACCAGCTGACGCAGGTGGTGAAGGGCGACCCACCACAGCTCAGCAGCTCCGAGGAGAGACAGTTCTCCCCCAAGTTCATCAACTTCGTCAACCTGTGCCTTACAAAGGACGAGTCAAAAAGGCCAAAGTACAAAGAGCTTCTGAAACATGCGTTCATCCAGATGTACGAGGAGCGCTCGGTGGACGTGGCCACTTACGTCTGCAGGATCCTGGATCAGATGCCACCGTCTCCCAGCTCCCCGATGTACGtggactgacacacacacacacacataaacacacgcacacacacacatctgaacgTCCACACGCTGTCTACAGATCTGCTTCATCACACAACTGCAGTATTAAACCAGGAAATGAGCATCTG
>TCONS_00051056
AAATCTGGTGGTGGACTTAAACTTTTGCACAATCAAACACTACTTCGCGCTAGTGAGAAATCGGCACAAGTCTACAATTTTGAGCTTCCATTGACTTTGGAGCAAAACGATTGACTCTTGGACGGTTGATTGGTCCTCTCTTTCATTGGATTAAGAGATTAAACTCACAGAAATCAGCCTTTTATTCAGACGTCTTCAATAATCATGTAAACGTAAAGCCCTGAAGTTAAATTTTGCCAATCCTCCAATCAAAACCACTTCCAGAATCACTTCCGGACTTCCTTTCCAGAACCCACACATAGAGCGGCTGCGAACACACAGTATCGAGTCGTCTGGGAAGCTGAAGATCTCAGCGGAGCAGCACTGCGATTTCACAGCAGAAGACCTGAAGGATCTCGGCGAGATCGGCAGAGGAGCGTATGGCTCGGTCAACAAGATGGCGCACAAACCCAGTGGACAAATCATGGCCGTCAAGAGGATTCGTTCAACAGTAGACGAGCGAGAACAGAAGCAGCTGCTGATGGATCTGGATGTGGTCATGAGGAGCAGCGACTGTCCGTACATCGTCCAGTTTTACGGGGCTCTTTTCAGAGAGGGGGATTGCTGGATATGCATGGAGCTCATGTCTACCTCCTTCGACAAATtctacaaatatgtttattcctCTTTAGACGAAGTGATTCCAGAGGAGATTTTAGGGAAAATAACATTAGCTACTGTGAAAGCACTTAACCACTTAAAAGAAAACTTGAAAATTATTCACAGAGACATAAAGCCATCAAATATCCTCCTGGACAGGAAAGGCAACATTAAACTGTGTGATTTTGGCATCAGTGGGCAGCTGGTTGACTCCATCGCCAAAACCAGAGACGCAGGCTGCAGACCGTATATGGCAccgGAGAGGATAGACCCCAGCGCCTCCAGACAGGGTTATGACGTGCGCTCGGATGTGTGGAGTTTGGGCATCACACTGTATGAGCTGGCCACGGGACGCTTCCCCTACCCCAAGTGGAACAGTGTGTTTGACCAGCTGACGCAGGTGGTGAAGGGCGACCCACCACAGCTCAGCAGCTCCGAGGAGAGACAGTTCTCCCCCAAGTTCATCAACTTCGTCAACCTGTG
>TCONS_00051057
AGCCCAGCGctgactgctgctgctgctggaagAGTCAAACCCAAATGGCGACGTCCAGCCCAAGCAGTAACCCAGCGTCAGCCTCCAACAACCCAACGCAGCTCCACCCGGCCCAGAGCCAGCACATCACCACCATGAGCAGCATGCAAGGTAAACGTAAAGCCCTGAAGTTAAATTTTGCCAATCCTCCAATCAAAACCACTTCCAGAATCACTTCCGGACTTCCTTTCCAGAACCCACACATAGAGCGGCTGCGAACACACAGTATCGAGTCGTCTGGGAAGCTGAAGATCTCAGCGGAGCAGCACTGCGATTTCACAGCAGAAGACCTGAAGGATCTCGGCGAGATCGGCAGAGGAGCGTATGGCTCGGTCAACAAGATGGCGCACAAACCCAGTGGACAAATCATGGCCGTCAAGAGGATTCGTTCAACAGTAGACGAGCGAGAACAGAAGCAGCTGCTGATGGATCTGGATGTGGTCATGAGGAGCAGCGACTGTCCGTACATCGTCCAGTTTTACGGGGCTCTTTTCAGAGAGGGGGATTGCTGGATATGCATGGAGCTCATGTCTACCTCCTTCGACA

Function

symbol description
map2k4a Predicted to enable JUN kinase kinase activity. Involved in JNK cascade. Acts upstream of or within determination of dorsal identity. Human ortholog(s) of this gene implicated in ovarian serous carcinoma; pancreatic cancer; and urinary bladder cancer. Orthologous to human MAP2K4 (mitogen-activated protein kinase kinase 4).

GO:

id name namespace
GO:0007254 JNK cascade biological_process
GO:0007257 activation of JUN kinase activity biological_process
GO:0048263 determination of dorsal identity biological_process
GO:0006468 protein phosphorylation biological_process
GO:0000187 activation of MAPK activity biological_process
GO:0016310 phosphorylation biological_process
GO:0016740 transferase activity molecular_function
GO:0005524 ATP binding molecular_function
GO:0008545 JUN kinase kinase activity molecular_function
GO:0000166 nucleotide binding molecular_function
GO:0004672 protein kinase activity molecular_function
GO:0004674 protein serine/threonine kinase activity molecular_function
GO:0016301 kinase activity molecular_function
GO:0004708 MAP kinase kinase activity molecular_function

KEGG: NA

ZFIN:

id description
ZDB-GENE-060512-98 Predicted to enable JUN kinase kinase activity. Involved in JNK cascade. Acts upstream of or within determination of dorsal identity. Human ortholog(s) of this gene implicated in ovarian serous carcinoma; pancreatic cancer; and urinary bladder cancer. Orthologous to human MAP2K4 (mitogen-activated protein kinase kinase 4).

Ensembl:

ensembl_id ENSDARG00000063583

RNA

RNA id representative length rna type GC content exon number start site end site
TCONS_00051053 False 1315 mRNA 0.50 12 10592597 10634438
TCONS_00051054 False 1373 mRNA 0.51 12 10592597 10634532
TCONS_00051055 False 1079 mRNA 0.51 9 10592598 10612186
TCONS_00051056 False 1122 mRNA 0.48 9 10596543 10621391
TCONS_00051057 True 585 mRNA 0.54 5 10604229 10634532

Neighbor

gene id symbol gene type direction distance location
XLOC_026140 elac2 coding downstream 10213 10535957 ~ 10582384 (-)
XLOC_026139 NA coding downstream 62701 10523450 ~ 10529896 (-)
XLOC_026138 pctp coding downstream 167284 10407458 ~ 10425313 (-)
XLOC_026136 NA coding downstream 198769 10252159 ~ 10393828 (-)
XLOC_026137 nog1 coding downstream 280345 10310090 ~ 10312252 (-)
XLOC_026142 si:ch73-1f23.1 coding upstream 17543 10652075 ~ 10677952 (-)
XLOC_026143 NA coding upstream 49790 10684322 ~ 10711294 (-)
XLOC_026144 NA coding upstream 57876 10692408 ~ 10693768 (-)
XLOC_026145 si:ch73-1f23.1 coding upstream 68352 10702884 ~ 10706846 (-)
XLOC_026146 zgc:112965 coding upstream 94438 10728970 ~ 10751491 (-)
XLOC_026135 BX539325.1 non-coding downstream 379377 10213098 ~ 10213220 (-)
XLOC_026134 BX539325.3 non-coding downstream 405446 10187033 ~ 10187151 (-)
XLOC_026133 BX539325.2 non-coding downstream 406244 10179191 ~ 10186353 (-)
XLOC_026150 NA non-coding upstream 308532 10943064 ~ 10994386 (-)
XLOC_026151 NA non-coding upstream 320177 10954709 ~ 11000449 (-)
XLOC_026153 NA non-coding upstream 383937 11018469 ~ 11049191 (-)

Expression


Co-expression Network