XLOC_026291 (nlk1)


Basic Information

Item Value
gene id XLOC_026291
gene name nlk1
gene type coding
species zebrafish (Danio rerio)
category of species model fish

Chromosome Information

Item Value
chromosome id NC_007114.7
NCBI id CM002887.2
chromosome length 62628489
location 21066315 ~ 21094525 (-)
genome version GRCz11_2017_zebrafish_Genome

Sequence

>TCONS_00051270
CATTCACTCATCCCTCCTTTCTTTCACTCCATCCCCCTCTTTCAACTCCTCCTTCTGCTCCCTCACTACCGCTGTTTCCAACAGCTGATTTCTAGATCGCGCAGAGGAACACGGCGAGAGATTTGGGGTTTTGGATCCTTGGCAGGTGAAGGATTTACCGCGAGTAAAAATGCAGGAAAAGCGCTGCGATCCTCCAGCGGCCGACATGAAGAACTGAGCTCCGCCGCCGCCGCTGCCATCAGCTCCGAGAGGATGGCTTTCCATGGATCCACTCGGCCGACAGTGTGTGGTAACTTGTTCCCAGCATCAGAGTTAGGCCACAAATATttttgtgtcaacaccacagccggCACTACCTCAACGGGCCTCGGCGCAACACCAAATCCGACTGGGCCCAACGCACCTGCTGGGACTCCCAGACACCCGGCGTCTCTCGGGGGCAGCGCTGGCGGAGGGGCGGCCATCCCGCAACCTCACAGTAACCCAGCTAGTGAGGTGCCAAGTCCTGCTGAAATGGAGCCTGATCGACCTATCGGTTACGGGGCGTTTGGAGTGGTCTGGTCTGTGACTGACCCTCGGGATGGACGCAAGGTGGCTCTGAAGAAAATGCCCAATGTCTTCCAGAACCTGGTCTCCTGCAAACGTGTGTTCAGGGAACTCCGGATGCTGTGTTTCTTTAAACATGACAACGTGCTTTCTGCCCTTGACATTCTCCAACCTCCACAAATCGACTGCTTTGAGGAGATATACGTGATCACTGAGCTCATGCAGAGTGACCTACATAAAGTCATCGTTTCCCCTCAGCCTCTCACCACCGATCACATCAAGGTGTTCCTCTACCAGATACTCAGGGGACTGAAGTACCTGCACTCAGCAGGCATTCTCCACAGAGACATCAAACCAGGGAACCTGCTGGTCAACAGCAACTGTCTGCTTAAGATCTGTGACTTTGGCCTGGCACGTGTTGAGGAGCCGGATCCCTCTCGTCACATGACCCAGGAGGTGGTGACGCAGTATTACCGTGCTCCAGAGGTGCTGATGGGATGCCAGCATTACACTTCATCTATAGATGTCTGGTCTGTTGGTTGCATCTTTGCCGAGCTGCTGGGCCGACGGATTCTCTTCCAGGCTCAGAGTCCCATACAGCAGTTGGATCTAATCACTGATCTCCTCGGGACTCCTCCTCTTTCTGCCATGACGTCTGCATGTGAAGGAGCTCGAGCGCACATTCTCAGAGGACCCCACAAACCACCGTCATTGTCTGTTCTGTACATGCTGTCAGATGGGGCAACACATGAAGCCGTTCATCTTTTGTGCCGAATGCTAGTTTTTGATCCAGCCAAGCGCATCTCCGGCAGTGACGCTCTGTCTCACCCGTATCTGGACGAGGGTCGTCTTCGCTACCACACCTGCATGTGCAAGTGTTGTTACTCTGTGCCCAGCGGGAGGGTTTACACCCGAGACTTTGAGCCTCCTGCGGATCGACCGTTCAGCCACAACTATGAGCAGAGCATGCACTCCGTCTGGCAGGGCAAAGAGCTCATCCATCGTTTTATAACAGAGCACCAGCAAGGCAAACGAGTGCCTTTGTGCATCAATCCCCAGAGCGCAGCCTTTAAAACCTTCATCAGATCCACAGCCTGGCATTCATCAAAGGTATCAAGGAAAGAGGAGAGATGAGTGATGAGGTGGACTCTGGGAAGTGTTGATCATAGAAGCGAGCTTGCATTGGAGATGATTGAAGATGTTCTTGATGGATCACACACCGCTTTTTGAACGAAGTCTCAGCACTCACCGCATGGGGGGGTTTCTCCAGAAAACACATTTTTCCAGTTCCACACAACACTTAAACGAAAAAAAAAGAGGTTCAGATGCTGCTGAGAACACTTTTATACAGAATGTGTGTGATTGAGGATTATGGGAAATAGTTTTTTTCCAtagggaaaagaaaaaaagaatctcATGGATTGTTGAATATTGAGCCAACATCAGTGTTGTGCAATACAGATTTCTGGAATAATGCAAATATGACGAGACTGCGCTGACCAGCATCAGATCAGTGCCCACAAGTCCTCAGCATCGCCCCTGCGGCCATCTCTATCCTCCAAACTCTGTCCATAGACTTTTATCACTGTGTTCCTTTTTGCGGGTTCCTTATACTTAGAAATTCTGCTAACCAAAAGTACTTCAAGTCTTCTTACTTTGTTACTACTTCCTCATGCTTTCTGTTCATCGCTCACATTtctttattttcagtgtttcttcTCAATGAAGCATCCTGCGCAAGTCATGTTGTATTCGAAGGCTATATAGGTATGACGTCGTCCATATTTGTTTTGAAACATCTTCCCAAAAGGTCCCGCCCCCTTTCAGGACCAAACCAGATTGACGTCAGCATGCTGCGTTCTGATTGGGTGAGGCTGAGAAGATAGATGgaatcttatttattttctcttctttaATTTATTGTCATCTTGTCCAGCTTGTTCGGTGTTGTGCTAGGCGGACCAGAGTGAAACCACCTGGTCtggcttgtttttatttttagctgtGCAGTTTAGGGAATGTGCAGtgttgtacctttttttttttttttttttttttaggatattTCATTACCTCAGCCGGCCCTCAGAGCTGGTGTATATAGAGACTCAACCCAATCGTTTATCGGAAATGTACTGTAATGCATTCGAATGACGTCAGGTgtgcgtgcgtatgtgtgtgtgcgtgtttggagCTGGACCGCAATCAGTCATTTAAGTTTTCCTTCAGATCGAGGAATTATTGGGACGGTGATGctgctgtttaatgtgtgtgtaataCCTCCGAAACCTCCCCGACTTATTTGTAAAGCAAACACGTCTACGACTCAGGTTTCATATTACTTCAATATGGACTGAAGACGTGGGTTTAGacagatatactgtatataagcaGTCGACGGTGCTGTCCTGGTTGGAAAAAAAAGTGTGGTACTGTAAATGTTTGCTTCCTACCACCAGGTGGCAGCATAAGCGCAGGGCAGGATTGGAAATATCAAGGCAGTTCCTCATCAATAATGTCTCTCAATGCATGTGAGTATGGACTTCACTTGGATTTGCAATTGCAGTGCATTGagttttattttagaaactttTTATATGTGCTGTTGCTATTTATGTTTATGATAGGAACACGTTTGGTTCTTTTTAGGGCTTATGTTTTCATGTATTGTGaccaatttattttgttttgtttttttggtatttttaagaCCACTTTTGCTATTGTGTTGGTAGATAAACTAGCAAAATAGTGACACCGGAATGAAGATAAGTGGGTCGGTATAGTCATTTTTGTGTCTTACCGACTGCCAAGCAGAAAGTGAACTTTTTAGGTAAATGGTGAATTTCCTTTTAGTCGTAAGATAATAGATGTTAGACATTTTTAAGATGAAACTGAAAACTTGATATTCGTGTTAATGACTATTAtggctttggaaaaaaaaatgattgaacaGTTGTTTTAAGATGGTTATTTTTTTCCCTTGTTATATGTtgttttagattttcttttttattattattattattttgtgtttgcattttagaagaaaaaaaagttttcggACTTTTGTGTTCCCAACAAATACTTGAAGTTTTTAAGaaaaaagagagcgagagagaagtGCATTAGGGTAAAATTGACATTAAAGAAACAGACACTGGAAA
>TCONS_00051271
TTTCTAGATCGCGCAGAGGAACACGGCGAGAGATTTGGGGTTTTGGATCCTTGGCAGGTGAAGGATTTACCGCGAGTAAAAATGCAGGAAAAGCGCTGCGATCCTCCAGCGGCCGACATGAAGAACTGAGCTCCGCCGCCGCCGCTGCCATCAGCTCCGAGAGGATGGCTTTCCATGGATCCACTCGGCCGACAGTGTGTGGTAACTTGTTCCCAGCATCAGAGTTAGGCCACAAATATttttgtgtcaacaccacagccggCACTACCTCAACGGGCCTCGGCGCAACACCAAATCCGACTGGGCCCAACGCACCTGCTGGGACTCCCAGACACCCGGCGTCTCTCGGGGGCAGCGCTGGCGGAGGGGCGGCCATCCCGCAACCTCACAGTAACCCAGCTAGTGAGGTGCCAAGTCCTGCTGAAATGGAGCCTGATCGACCTATCGGTTACGGGGCGTTTGGAGTGGTCTGGTCTGTGACTGACCCTCGGGATGGACGCAAGGTGGCTCTGAAGAAAATGCCCAATGTCTTCCAGAACCTGGTCTCCTGCAAACGTGTGTTCAGGGAACTCCGGATGCTGTGTTTCTTTAAACATGACAACGTGCTTTCTGCCCTTGACATTCTCCAACCTCCACAAATCGACTGCTTTGAGGAGATATACGTGATCACTGAGCTCATGCAGAGTGACCTACATAAAGTCATCGTTTCCCCTCAGCCTCTCACCACCGATCACATCAAGGTGTTCCTCTACCAGATACTCAGGGGACTGAAGTACCTGCACTCAGCAGGCATTCTCCACAGAGACATCAAACCAGGGAACCTGCTGGTCAACAGCAACTGTCTGCTTAAGATCTGTGACTTTGGCCTGGCACGTGTTGAGGAGCCGGATCCCTCTCGTCACATGACCCAGGAGGTGGTGACGCAGTATTACCGTGCTCCAGAGGTGCTGATGGGATGCCAGCATTACACTTCATCTATAGATGTCTGGTCTGTTGGTTGCATCTTTGCCGAGCTGCTGGGCCGACGGATTCTCTTCCAGGCTCAGAGTCCCATACAGCAGGTGATGATGGACACTAGCTTTAAAGGCCTAAAAATTTtggcctttttacaagatgttaaaTACGTTTTGGTGTCCTCAAGAAAATGTCAGTGAAGATTCAGGTCAAAATGCAAAATCAGATAATGTATaatacattctttaaaatgtagttttggGAAAGCGTTGTTTTCcttttgtacatttaaatgaaaatgagctggttctcctcACCCACTCTTGGGACATTTCTCTTCAGAGAAGGATAACCAGGGTCAGATGTCAGGATAAACCGCAAAATCTCAGACATGATGAAACAGAGACCCACAGTCACAAATACCACAGTAAGATGAATGAGCTGCACACAAACGCTGTTGTAACAAGAGTTGGAGCAGATCTTTTAATccaagtttctttgcaaatcctgtcttgtGGACATGAATATACGCGCATGTCAACCAAtctcagtgggcggggaaaactgCAATGCTATGTCAAAGTGGGCAACAATAAAAACTGGGATTCAGAAAATTTGaagtcaaatttaaaaaataaataaataaagagacttgTTTGTGTCACTCCAACATGACTGTGGACGCACTAATCatacacatttctgtccaaacagcttccaaaagttgatttagCATGATATGTGCCCTTTAGAGGGGATATAGAATGTGTTGATACAATGTTAAACTGTTCTCCGATTTTTAAATAGAGCTTATGTGGCTTAGGTATGTGCAAAAATTATCcagaaacacttttacaagtcaATTTCCAACCCTAGGAATTCAGCTCAGTGACTGAATGAAAAGAAAGTTTGGTCCTTTGTTGTGGATGAAATATAGCGTAAATCATAATTGTACTTGGCAAAAGTGGGCAGACTGAAATGTATTTAGAATTGTATTTTGTTGCTTTAACGTATGTGACAACACAGACAGGATTTAAATATCAACCTTTAAATTTACCATGTTGCTTTTACTCCAGAAAAATGAGAGAAAGAGCAGAGAGATATGACACCATGCGTAAACATGCATTAGACATTGATGCTCAGTAGTTTACATGTTTACCTCATTACAAACCTACACGGATGTGTtacaaatattgtataatatttttgtaatatacaggttaaccctttgactgccacTCTATCAAACGGTTGACCATATATTTACTGTTTACTGTTTTTAATATTGACTCTAAAAGTCATTTAAAGTAtgcctgttttaaataatggcttcCACACAGCATTgttgctttacaaaaaaaaaa
>TCONS_00051272
TAGGATGGCTTTCCATGGATCCACTCGGCCGACAGTGTGTGGTAACTTGTTCCCAGCATCAGAGTTAGGCCACAAATATttttgtgtcaacaccacagccggCACTACCTCAACGGGCCTCGGCGCAACACCAAATCCGACTGGGCCCAACGCACCTGCTGGGACTCCCAGACACCCGGCGTCTCTCGGGGGCAGCGCTGGCGGAGGGGCGGCCATCCCGCAACCTCACAGTAACCCAGCTAGTGAGGTGCCAAGTCCTGCTGAAATGGAGCCTGATCGACCTATCGGTTACGGGGCGTTTGGAGTGGTCTGGTCTGTGACTGACCCTCGGGATGGACGCAAGGTGGCTCTGAAGAAAATGCCCAATGTCTTCCAGAACCTGGTCTCCTGCAAACGTGTGTTCAGGGAACTCCGGATGCTGTGTTTCTTTAAACATGACAACGTGCTTTCTGCCCTTGACATTCTCCAACCTCCACAAATCGACTGCTTTGAGGAGATATACGTGATCACTGAGCTCATGCAGAGTGACCTACATAAAGTCATCGTTTCCCCTCAGCCTCTCACCACCGATCACATCAAGGTGTTCCTCTACCAGATACTCAGGGGACTGAAGTACCTGCACTCAGCAGGCATTCTCCACAGAGACATCAAACCAGGGAACCTGCTGGTCAACAGCAACTGTCTGCTTAAGATCTGTGACTTTGGCCTGGCACGTGTTGAGGAGCCGGATCCCTCTCGTCACATGACCCAGGAGGTGGTGACGCAGTATTACCGTGCTCCAGAGGTGCTGATGGGATGCCAGCATTACACTTCATCTATAGATGTCTGGTCTGTTGGTTGCATCTTTGCCGAGCTGCTGGGCCGACGGATTCTCTTCCAGGCTCAGAGTCCCATACAGCAGGTGATGATGGACACTAGCTTTAAAGGCCTAAAAATTTtggcctttttacaagatgttaaaTACGTTTTGGTGTCCTCAAGAAAATGTCAGTGA

Function

symbol description
nlk1 Predicted to enable MAP kinase activity. Acts upstream of or within negative regulation of Notch signaling pathway; positive regulation of Wnt signaling pathway; and positive regulation of neurogenesis. Predicted to be active in cytoplasm and nucleus. Is expressed in several structures, including eye; immature eye; neural plate; notochord; and otic vesicle. Orthologous to human NLK (nemo like kinase).

GO:

id name namespace
GO:0045746 negative regulation of Notch signaling pathway biological_process
GO:0035556 intracellular signal transduction biological_process
GO:0030177 positive regulation of Wnt signaling pathway biological_process
GO:0006468 protein phosphorylation biological_process
GO:0010468 regulation of gene expression biological_process
GO:0050769 positive regulation of neurogenesis biological_process
GO:0016310 phosphorylation biological_process
GO:0005634 nucleus cellular_component
GO:0005737 cytoplasm cellular_component
GO:0016740 transferase activity molecular_function
GO:0005524 ATP binding molecular_function
GO:0000166 nucleotide binding molecular_function
GO:0004672 protein kinase activity molecular_function
GO:0004674 protein serine/threonine kinase activity molecular_function
GO:0016301 kinase activity molecular_function
GO:0004707 MAP kinase activity molecular_function

KEGG: NA

ZFIN:

id description
ZDB-GENE-040701-1 Predicted to enable MAP kinase activity. Acts upstream of or within negative regulation of Notch signaling pathway; positive regulation of Wnt signaling pathway; and positive regulation of neurogenesis. Predicted to be active in cytoplasm and nucleus. Is expressed in several structures, including eye; immature eye; neural plate; notochord; and otic vesicle. Orthologous to human NLK (nemo like kinase).

Ensembl:

ensembl_id ENSDARG00000006566

RNA

RNA id representative length rna type GC content exon number start site end site
TCONS_00051270 False 3713 mRNA 0.45 12 21066315 21094525
TCONS_00051271 False 2318 mRNA 0.44 7 21078250 21094437
TCONS_00051272 True 994 mRNA 0.53 6 21079414 21087959

Neighbor

gene id symbol gene type direction distance location
XLOC_026290 tlcd3ba coding downstream 3537 21044154 ~ 21062778 (-)
XLOC_026289 rundc3aa coding downstream 28475 21018053 ~ 21037840 (-)
XLOC_026288 fam117aa coding downstream 55336 20983395 ~ 21010979 (-)
XLOC_026287 slc35b1 coding downstream 83609 20963162 ~ 20982706 (-)
XLOC_026286 ndufa4l coding downstream 109232 20947560 ~ 20957083 (-)
XLOC_026292 maza coding upstream 1502 21096027 ~ 21118969 (-)
XLOC_026293 cdipt coding upstream 30768 21125293 ~ 21137362 (-)
XLOC_026294 taok2a coding upstream 44015 21138540 ~ 21185016 (-)
XLOC_026295 CR387996.1 coding upstream 106903 21201428 ~ 21206946 (-)
XLOC_026296 tcap coding upstream 146069 21240594 ~ 21242460 (-)
XLOC_026285 NA non-coding downstream 150605 20901066 ~ 20915710 (-)
XLOC_026283 NA non-coding downstream 664591 20130274 ~ 20401724 (-)
XLOC_026277 CR855865.1 non-coding downstream 1073852 19986341 ~ 19992463 (-)
XLOC_026276 NA non-coding downstream 1092695 19971681 ~ 19973620 (-)
XLOC_026274 BX572620.1 non-coding downstream 1245508 19813248 ~ 19820807 (-)
XLOC_026301 CR790381.1 non-coding upstream 522395 21616920 ~ 21617040 (-)
XLOC_026303 NA non-coding upstream 1058082 22152607 ~ 22155523 (-)
XLOC_026308 NA non-coding upstream 1314265 22408790 ~ 22421923 (-)
XLOC_026310 NA non-coding upstream 1944983 23039508 ~ 23069636 (-)

Expression


Co-expression Network

Homologous

species gene id symbol gene type chromosome NCBI id location
grasscarp (Ctenopharyngodon idella) CI01000034_03358125_03363411 NA coding CI01000034 null 3355709 ~ 3364036 (+)