XLOC_026389 (abat)


Basic Information

Item Value
gene id XLOC_026389
gene name abat
gene type coding
species zebrafish (Danio rerio)
category of species model fish

Chromosome Information

Item Value
chromosome id NC_007114.7
NCBI id CM002887.2
chromosome length 62628489
location 27832500 ~ 27880229 (-)
genome version GRCz11_2017_zebrafish_Genome

Sequence

>TCONS_00051435
GTGAAGTGAAAGGCAGGTGCTGtgtgctgtctctctctctctctctgtctgtgtctcGGTGAGTGCTACACATGGCTTCCTCACTCCTGACCCGTCAGCTGGCTCTTTCCCTCCAGCAAAACCTGCGTCTCGCTGCTCCAGGTTCCAGATATGTCAGCAAAACTGCTACAAAGACTGTTTCAGAGTTTGAATATGATGCCCCATCCATGAAGACTACTGTGCCCGGTCCAAAgtccaagGAGCTGCTGAGACAACTTGGAGAGATTCAGAACACTGGAGCTATTCACTTTTTCTGCAACTATGAGGAGAGCAGAGGGAATTACCTGGTGGACGTTGACGGAAACCGAATGCTGGACGTGTACACACAAATCTCCTCCATTCCCATCGGTTACAATCATCCAGCCTTAATGAAAGTGATGACCAATCCAAATAATGTGagtgCATTTGTCAACCGGCCGGCACTTGGTATCCTGCCACCTGAGAACTTTCCAGAGAAACTGGCGGAGAGCCTGTTGTCGATCGCCCCCAGCGGGATGACAAAAGTGCAAACCATGGCTTGTGGCTCCTGCTCCAATGAGAATGCTTTCAAGAGCATGTTTATCTGGTACAGAAATAAAGAAAGAGGATATGCAACCCCCTCCGAAGAGGAAGTCGGCACTTGCATGGTCAATCAGagTCCTGGATGTCCAGATTTGAGCATTTTGTCTTTCATGGGAGCTTTCCATGGGAGGACTTTGGGTTGCCTGGCCACAACACATTCCAAGGCCATCCACAAGCTGGACATCCCATCCTTCGACTGGCCTATCGCACCCTTCCCGAAGCTGCGGTATCCTCTGGAGGAGTTTGAGAGGGAGAATGCTCAGGAGGAAGCCCGCTGTCTGGAGGAGGTTGAGGATCTGATAGTGAAGTGGAGGCAGAAGGGCAAACCGGTGGCTGGTATTGTGATCGAGCCCATCCAAGCTGAAGGAGGAGACAATCACGCCTCACCAGACTTCTTCATCAAACTAAGAAACATTGCACGCAAGCATGGCTGTGGTTTCCACGTTGATGAGGTTCAGACCGGTGGAGGAGCAACGGGCAAATTCTGGGCTCATGAGCACTGGGGTCTGGACGACCCTGCGGATTTGGTGTCCTTCAGCAAGAAGATGCTGACCGGAGGATATTTTCACAGAGATGAACTGCAGCCTGACAAACCTTACAGAATCTTCAACACGTGGATGGGAGACCCTTCCAAGAATCTGTTCCTATCAGAGGTGCTCAATGTGATCAGGAGAGAGAACCTTCTGGAGCAGGTGACGCGTTCAGGCAAAGCTCTTCTGCAGGGGCTCTATGCTCTACAGAGTCAGTATCCTCATCTCTTGAGCGGAGCCCGTGGTCAGGGAACATTCTGTGCCATCAACGCCAGCAGTGATGCCACACGTGACTCCATCATGCTGAAGGCCAGGAACAAGGGTGTATTTCTGGGTTCCTGTGGAGAAAAATCCATCCGTTTCCGTCCTGCTCTAGTCTTCAAGGAGTATCATGTCCATCAGCTGCTGAACATCCTGAATGACGTCCTGGCTGAGCATAAATAGAGTAGTGTCTGGCCTTCATCATCAAACACACAAAGAGTACTGGAGGCTTTCCAGCAGCCTCACACTATTAACTGCTCTCTGTCTCTCCTGTCATCTCTCATTAAGGACGACACCAATCTGTCTTCTGTCTCCTCTCATTCATCTCATCTCCACCATAATTCTCTTGACCAAACTGATTTTAGCCCAACGCTAACCAAGGGTCATTCACTGAAATGATAGACCTAGAAAGCGACTGATGTCACAGCGTAGCTTGTGAAATGTGAGGTCAGATGTTTTCCAACCGTCCAAAATCTGACCAATAAAGCAGTGTAGTAGAGACGGGGATTTCCAATCGCAATATATTTCTATtttctatccctttaaatgtcgTATAAAGGCATGAGGAAATGTTTAAAGCATGAAAAGATGAGCAAAGACGTTATAGAGATAAATGATAACATAGATAGATATAACTGCACTGGAATGCTCTTTAGGATGTCACTTTGCAGATGGTCCTGTCTGAaataaaggtatagttcactcaaaaaaaaaagaaaaaaagaaactctacTAATCTTTTTGTAGAATGTTTGAAACTAGTAACCATTTACCTCCATTTTGTTCTCCCTATTTTGCATGTTGATGTTTACtgttttcaaacattcttcaaatgatctttgtgtgtttttgaatttctgggtgaactatactTTAAAAACTGATGGTGTTGGATTGATCAGGCTGAAAATTCTGAGAAGGTGAATTGTAGGTTTGTGTAAAGATGTCTCTGAAGCTGAAGATCTTCAATCAATCGGCATGTCACTTTTGAGGTGaccttattattttaatattcctCAATCATAGAGAGATGTGGACTCTAATCCACATATTTAGGAACGCAAAAACCTGTAAAGCACAAACCGGTTTGGTAACGTGATGCCTGATGGTTTTTCGCTTCCGCATGCATTATCAGGCAACAATGAAAGTCTTAACCGTCCATCAGATCCAACAATAGAAATCTGTCAGGGAGAGcgttttaaaagcacaaactcaTATTGACCATGCTCTGCTCAGGTGAACATGATCCCCCTGCTGTTTCTCATTTACAGGCCGTGCTGGGAAAAGCGATATTGTTCTGCTGGCTGGTATTGACATGGTGTGATCTTCATGTGATGGTTTTGACAGCCTGTTCGTGTTTGCAATGTTCGGGGTGATTCTCCTGCTCCAGTTTCTCCAAGCTGACATGTCCCTTCAGCTTGATTGTTTTAAACGTTCTTTATATATTTGGATGCTGCCTTCATGTGCTACAGGGAAGTTcctaaaggggcagttcacccaaaaattagaTAGTCAGCCTCATTTATTTAACCTCTGCTTATTCCAGacatatttgagtttcttctgatgaacacaaaggaAGCATAAcagcctttgacttccatagtaattttttcTTTCCCCTTCTATGGATGTTGATGGTGTTTTTTCCccacaacattcttcagaatatctttctttgtgttcatcagaagaaataaatacaCTTCTGACTTTTATGTGAGTAAACCGTGAggaaattttcacttttgggtgaattatctctttaagTGTACATGGATTTCAAATTATACACCATTTGAGTTTTCAGACTAGACACTTGTCATTTTGTGTTGTCCGGatccaaatatttacattttaaaaagatctTAGAATTTGTTTTAACTATAGTTGCTGATGTGGTTTAATTGTTTAAGCACTTGTCGGCTATTGTTTTTGCATTCTACGGTAGTTTGATCCTATCGCACTGGTGCAGACGAAAAGTGCCACttctttaaaatacaaacattgTTTTCTTGGTGTCCATTTGTGACTCTGCATACTTTTGAAACTGCCAGAACATCCTCAGTTTTATATGAAGTAACATTAAGATTGTGCGCATCTGATGTTCAATACCTCGAATCGTCAAAGAGGCAACTTAAGTTTCAAAGAGTAGTCTTAAAAATGGGGCAGCGCATGTGGAGTACTCGCATACTACCcactaaaccagtgtttctcaaccacgttcctagaggaccaccagctctgcatattttccacatctccttaaccaaacacacctgattcagatcatcagcagactgaaagacctgtaatgggtgtgagaGACAAAGTAGACATCTAAAttatgcagtgctggtggtccctctaggaacgtggttgagaaacactgcactaaaTGGTGGTGAAAATCTTTTGTGACATCAATTCTGAGACTTAAAATGCATTGCTTTTGCTCTTGAATTGATTCAAAGTTAAGCTTTTAGCAACAGACGGTGCTGTATATTGCAGGTATTCAGTCGTACAGTGTTCATAGTACAATTTGATTTATCTTCGAGACATACATCAACTTGCATGACTCAGCCAAAATCCTGTGTATTTGAGTGTATGGTTAAATACTAgcccagagcaccatctgctgttaaaaactaaactcTCAATCAATTCAAGAGATTATAAAGATAAATTTGAAATAGTCTCAACTTTTCACCATATTTCTACTGTTCACTCATGTCttatacacatttaaatgttAAACAAACATACTCTGGGCTTTATGTCTAAAAACGGAAGTATACTTTAGGTTTAAAGTGCTCAGGTGTGATAATttatacaccaaaaaaaaaacaaatgaagaaagtATTGAACATGTAAATGTTGGTATATGTAAAACCTAAAGTATACAGCACTTTTTACACAGTCAAACGCCTTTCGAAGTACACTTCATTTAACTATTACGCGTACAAAACAAACTGCAatacaaatgtacaaatgagTGTACTTCACGACATACCATCTATTGTCTTTGTAGCACATGTTCTAgtctggagagccggtgtcctgcatatttaagttccaaccccaattaaacacagctgaaccagctaatcaagctctttctaggcatactagaaacttccaggcaggtgtgttgaaggaagttggagctatacaatgcagaacaccagccctccaggaatgagtttggacacccctgttctagcaTGTTCCATTTATGCAGCTTTACAATcaaaagtagctaaatgttgccagatgacATCATGGACTAATTTGTATATCAGTGACGTCATGTAAGTTAGCCCGTCATGTTTCTACTCTGAGGTGCcgtgtattaaattatatttgaatattacatccagatgcacaataCATGAGTTCTTATTAACATATTTCGTTGCGTGATGACGTCATTGTGTAATCGCAACTCAAAACTACATCTTTATGTAGTATACGAAATAATGAATGCTTTCTCAAATTGACATGGCCATCCCAGcacaaacattatttgaaatatgtccattAAGATTTCTATGAAAAATACAGTTTACtatttttaaaaggaacactttttGATTACTGATTGATGAacactttttaaagattttttttttttttaaatataacactgataatgaaCATTTACATtcttctaaaccaggggtgtccaaacttggtcctggagggccagtgtcctgcagagtttagctccaacttgccttaataaaccagcaaggatgtttctagaaagcctagtaagagcttgattggcacacccaggtgtgtctgactggggttggaactaaactttgcaggacaaagATTGTTCtaaacaatcacagcttgtgtacttgttttaacttgtgaaattaacacatttgtgaaagtgacaaaTTTTATCACTATTAGAATTTATTACTACATGAATTACCAAGAATTATACATGTTTATTATACATTAACAGTAAATtgctagctcagattgttttCATAACTGAGTAAAGCCTTGAAACTGctcttttgagtcactttttaaaaattgctacaagtagccaaatgaatgttaaaaactgctaaatttgttgctaggtgctttttgaaaaaaaaaaaaaggttgctagggtagtatgaaaagttgttaaatctagcaacaaaattgctaagttggcaacactgttcTGAAGCGGTCTAACTTCAGACTTAAAAgcttatatttataatttcagcagGATCTCATTAGAAAGCATAACTATTTTACAGATGAG
>TCONS_00051436
CTTTCTCCTCTTTTCTTTCTCGTGGTTCCACCGAAAACCTGCTAGGTTAAATTCTCGAACGTCAGACACGAAGGTGAAGTGAAAGGCAGGTGCTGtgtgctgtctctctctctctctctgtctgtgtctcGGTGAGTGCTACACATGGCTTCCTCACTCCTGACCCGTCAGCTGGCTCTTTCCCTCCAGCAAAACCTGCGTCTCGCTGCTCCAGGTTCCAGATATGTCAGCAAAACTGCTACAAAGACTGTTTCAGAGTTTGAATATGATGCCCCATCCATGAAGACTACTGTGCCCGGTCCAAAgtccaagGAGCTGCTGAGACAACTTGGAGAGATTCAGAACACTGGAGCTATTCACTTTTTCTGCAACTATGAGGAGAGCAGAGGGAATTACCTGGTGGACGTTGACGGAAACCGAATGCTGGACGTGTACACACAAATCTCCTCCATTCCCATCGGTTACAATCATCCAGCCTTAATGAAAGTGATGACCAATCCAAATAATGTGagtgCATTTGTCAACCGGCCGGCACTTGGTATCCTGCCACCTGAGAACTTTCCAGAGAAACTGGCGGAGAGCCTGTTGTCGATCGCCCCCAGCGGGATGACAAAAGTGCAAACCATGGCTTGTGGCTCCTGCTCCAATGAGAATGCTTTCAAGAGCATGTTTATCTGGTACAGAAATAAAGAAAGAGGATATGCAACCCCCTCCGAAGAGGAAGTCGGCACTTGCATGGTCAATCAGagTCCTGGATGTCCAGATTTGAGCATTTTGTCTTTCATGGGAGCTTTCCATGGGAGGACTTTGGGTTGCCTGGCCACAACACATTCCAAGGCCATCCACAAGCTGGACATCCCATCCTTCGACTGGCCTATCGCACCCTTCCCGAAGCTGCGGTATCCTCTGGAGGAGTTTGAGAGGGAGAATGCTCAGGAGGAAGCCCGCTGTCTGGAGGAGGTTGAGGATCTGATAGTGAAGTGGAGGCAGAAGGGCAAACCGGTGGCTGGTATTGTGATCGAGCCCATCCAAGCTGAAGGAGGAGACAATCACGCCTCACCAGACTTCTTCATCAAACTAAGAAACATTGCACGCAAGCATGGCTGTGGTTTCCACGTTGATGAGGTTCAGACCGGTGGAGGAGCAACGGGCAAATTCTGGGCTCATGAGCACTGGGGTCTGGACGACCCTGCGGATTTGGTGTCCTTCAGCAAGAAGATGCTGACCGGAGGATATTTTCACAGAGATGAACTGCAGCCTGACAAACCTTACAGAATCTTCAACACGTGGATGGGAGACCCTTCCAAGAATCTGTTCCTATCAGAGGTGCTCAATGTGATCAGGAGAGAGAACCTTCTGGAGCAGGTGACGCGTTCAGGCAAAGCTCTTCTGCAGGGGCTCTATGCTCTACAGAGTCAGTATCCTCATCTCTTGAGCGGAGCCCGTGGTCAGGGAACATTCTGTGCCATCAACGCCAGCAGTGATGCCACACGTGACTCCATCATGCTGAAGGCCAGGAACAAGGGTGTATTTCTGGGTTCCTGTGGAGAAAAATCCATCCGTTTCCGTCCTGCTCTAGTCTTCAAGGAGTATCATGTCCATCAGCTGCTGAACATCCTGAATGACGTCCTGGCTGAGCATAAATAGAGTAGTGTCTGGCCTTCATCATCAAACACACAAAGAGTACTGGAGGCTTTCCAGCAGCCTCACACTATTAACTGCTCTCTGTCTCTCCTGTCATCTCTCATTAAGGACGACACCAATCTGTCTTCTGTCTCCTCTCATTCATCTCATCTCCACCATAATTCTCTTGACCAAACTGATTTTAGCCCAACGCTAACCAAGGGTCATTCACTGAAATGATAGACCTAGAAAGCGACTGATGTCACAGCGTAGCTTGTGAAATGTGAGGTCAGATGTTTTCCAACCGTCCAAAATCTGACCAATAAAGCAGTGTAGTAGAGACGGGGATTTCCAATCGCAATATATTTCTATtttctatccctttaaatgtcgTATAAAGGCATGAGGAAATGTTTAAAGCATGAAAAGATGAGCAAAGACGTTATAGAGATAAATGATAACATAGATAGATATAACTGCACTGGAATGCTCTTTAGGATGTCACTTTGCAGATGGTCCTGTCTGAaataaaggtatagttcactcaaaaaaaaaa
>TCONS_00051437
TTTCTTTCTCGTGGTTCCACCGAAAACCTGCTAGGTTAAATTCTCGAACGTCAGACACGAAGGTGAAGTGAAAGGCAGGTGCTGtgtgctgtctctctctctctctctgtctgtgtctcGGTGAGTGCTACACATGGCTTCCTCACTCCTGACCCGTCAGCTGGCTCTTTCCCTCCAGCAAAACCTGCGTCTCGCTGCTCCAGGTAAAAATGGATACTATTAAGTCTGAAAAGCTTGATGACATTCCACTTAAACTGACAATACATTTACAGTGCCTGTAGAAATTCATCATACCCCTTTGAAACAATTACTTTTTGTCACacagcctgaaatcaaatcactttCCAAACAACTTTTCcagcctttgaaatgtttttgtagccttCTCCTAACCTGTGCCTTTTTACGACTTTATCCTAAAGGTTCTTTGAAAGCAGGGTGCAATGTGAGTAAAGATTTTCACAGAGTATGGTTTTTACTGATGGGCACAGTACAACAACAATATGATTCTGATATTAGCACGATTTAGACAAGACTCCGATTAAGAATCTACATTTTAAACAGAGATTTTTAATTACCTAAACTTGTACTCAAAGTAAAATCAAGTCCAAttaggacatatatatatatatatatatatatatatatatatatatatattttagt

Function

symbol description
abat Predicted to enable 4-aminobutyrate transaminase activity and pyridoxal phosphate binding activity. Predicted to be involved in gamma-aminobutyric acid catabolic process. Predicted to act upstream of or within gamma-aminobutyric acid metabolic process and neurotransmitter catabolic process. Predicted to be active in mitochondrion. Is expressed in blood; liver; nervous system; pronephric duct; and yolk syncytial layer. Human ortholog(s) of this gene implicated in Alzheimer's disease; GABA aminotransferase deficiency; and Huntington's disease. Orthologous to human ABAT (4-aminobutyrate aminotransferase).

GO:

id name namespace
GO:0009448 gamma-aminobutyric acid metabolic process biological_process
GO:0009450 gamma-aminobutyric acid catabolic process biological_process
GO:0005739 mitochondrion cellular_component
GO:0003867 4-aminobutyrate transaminase activity molecular_function
GO:0016740 transferase activity molecular_function
GO:0030170 pyridoxal phosphate binding molecular_function
GO:0008483 transaminase activity molecular_function
GO:0003824 catalytic activity molecular_function

KEGG:

id description
ko00640 Propanoate metabolism
ko00650 Butanoate metabolism
ko00250 Alanine, aspartate and glutamate metabolism
ko00280 Valine, leucine and isoleucine degradation
ko00410 beta-Alanine metabolism
ko04727 GABAergic synapse
ko01007 Amino acid related enzymes

ZFIN:

id description
ZDB-GENE-031006-4 Predicted to enable 4-aminobutyrate transaminase activity and pyridoxal phosphate binding activity. Predicted to be involved in gamma-aminobutyric acid catabolic process. Predicted to act upstream of or within gamma-aminobutyric acid metabolic process and neurotransmitter catabolic process. Predicted to be active in mitochondrion. Is expressed in blood; liver; nervous system; pronephric duct; and yolk syncytial layer. Human ortholog(s) of this gene implicated in Alzheimer's disease; GABA aminotransferase deficiency; and Huntington's disease. Orthologous to human ABAT (4-aminobutyrate aminotransferase).

Ensembl:

ensembl_id ENSDARG00000006031

RNA

RNA id representative length rna type GC content exon number start site end site
TCONS_00051435 False 5673 mRNA 0.41 15 27832500 27868183
TCONS_00051436 False 2179 mRNA 0.48 16 27836067 27880229
TCONS_00051437 True 666 lncRNA 0.38 2 27867580 27880218

Neighbor

gene id symbol gene type direction distance location
XLOC_026388 dnase1 coding downstream 48043 27778975 ~ 27784457 (-)
XLOC_026387 NA coding downstream 49208 27777362 ~ 27783292 (-)
XLOC_026386 PDE6G coding downstream 119320 27706113 ~ 27713180 (-)
XLOC_026385 si:ch211-157c3.4 coding downstream 184655 27642386 ~ 27647845 (-)
XLOC_026384 NA coding downstream 230688 27595037 ~ 27601812 (-)
XLOC_026390 mettl22 coding upstream 4456 27884685 ~ 27915270 (-)
XLOC_026391 NA coding upstream 35995 27916224 ~ 27927053 (-)
XLOC_026392 NA coding upstream 41558 27921787 ~ 27924016 (-)
XLOC_026393 rbfox1 coding upstream 102040 27982269 ~ 28428198 (-)
XLOC_026394 NA coding upstream 564005 28444234 ~ 28502493 (-)
XLOC_026383 NA non-coding downstream 390007 27408273 ~ 27442493 (-)
XLOC_026382 NA non-coding downstream 541720 27288743 ~ 27290780 (-)
XLOC_026381 CR954963.2 non-coding downstream 749086 27083298 ~ 27083414 (-)
XLOC_026379 CR954963.1 non-coding downstream 774465 27045647 ~ 27058035 (-)
XLOC_026395 NA non-coding upstream 579105 28459334 ~ 28462351 (-)
XLOC_026397 NA non-coding upstream 815533 28695762 ~ 28698856 (-)

Expression


Co-expression Network