Gene
RNA
| Item | Value |
|---|---|
| gene id | XLOC_026582 |
| gene name | thraa |
| gene type | coding |
| species | zebrafish (Danio rerio) |
| category of species | model fish |
| Item | Value |
|---|---|
| chromosome id | NC_007114.7 |
| NCBI id | CM002887.2 |
| chromosome length | 62628489 |
| location | 34688022 ~ 34753605 (-) |
| genome version | GRCz11_2017_zebrafish_Genome |
| symbol | description |
|---|---|
| thraa | Enables nuclear receptor activity. Involved in negative regulation of transcription by RNA polymerase II and positive regulation of transcription by RNA polymerase II. Acts upstream of or within several processes, including neural crest cell development; thyroid hormone mediated signaling pathway; and ventricular system development. Located in nucleus. Is expressed in several structures, including blastodisc; muscle; nervous system; optic cup; and pleuroperitoneal region. Used to study hypothyroidism. Human ortholog(s) of this gene implicated in congenital nongoitrous hypothyroidism 6 and renal cell carcinoma. Orthologous to human THRA (thyroid hormone receptor alpha). |
| id | name | namespace |
|---|---|---|
| GO:0006355 | regulation of transcription, DNA-templated | biological_process |
| GO:0030154 | cell differentiation | biological_process |
| GO:0021591 | ventricular system development | biological_process |
| GO:0007275 | multicellular organism development | biological_process |
| GO:0000122 | negative regulation of transcription by RNA polymerase II | biological_process |
| GO:0045892 | negative regulation of transcription, DNA-templated | biological_process |
| GO:0045893 | positive regulation of transcription, DNA-templated | biological_process |
| GO:0014032 | neural crest cell development | biological_process |
| GO:0002154 | thyroid hormone mediated signaling pathway | biological_process |
| GO:0009725 | response to hormone | biological_process |
| GO:0045944 | positive regulation of transcription by RNA polymerase II | biological_process |
| GO:0009755 | hormone-mediated signaling pathway | biological_process |
| GO:0005634 | nucleus | cellular_component |
| GO:0043565 | sequence-specific DNA binding | molecular_function |
| GO:0005515 | protein binding | molecular_function |
| GO:0046872 | metal ion binding | molecular_function |
| GO:0003677 | DNA binding | molecular_function |
| GO:0004879 | nuclear receptor activity | molecular_function |
| GO:0003700 | DNA-binding transcription factor activity | molecular_function |
| GO:0000978 | RNA polymerase II cis-regulatory region sequence-specific DNA binding | molecular_function |
| GO:0003707 | steroid hormone receptor activity | molecular_function |
| GO:0008270 | zinc ion binding | molecular_function |
| id | description |
|---|---|
| ZDB-GENE-990415-263 | Enables nuclear receptor activity. Involved in negative regulation of transcription by RNA polymerase II and positive regulation of transcription by RNA polymerase II. Acts upstream of or within several processes, including neural crest cell development; thyroid hormone mediated signaling pathway; and ventricular system development. Located in nucleus. Is expressed in several structures, including blastodisc; muscle; nervous system; optic cup; and pleuroperitoneal region. Used to study hypothyroidism. Human ortholog(s) of this gene implicated in congenital nongoitrous hypothyroidism 6 and renal cell carcinoma. Orthologous to human THRA (thyroid hormone receptor alpha). |
| ensembl_id | ENSDARG00000000151 |
| RNA id | representative | length | rna type | GC content | exon number | start site | end site |
|---|---|---|---|---|---|---|---|
| TCONS_00051783 | False | 1470 | mRNA | 0.52 | 9 | 34688022 | 34717882 |
| TCONS_00051784 | False | 2292 | mRNA | 0.50 | 10 | 34697278 | 34753605 |
| TCONS_00051785 | False | 1324 | mRNA | 0.53 | 9 | 34697821 | 34724879 |
| TCONS_00051786 | False | 651 | lncRNA | 0.53 | 3 | 34701214 | 34706737 |
| TCONS_00051787 | True | 334 | processed_transcript | 0.46 | 2 | 34743579 | 34753541 |
| gene id | symbol | gene type | direction | distance | location |
|---|---|---|---|---|---|
| XLOC_026581 | znfl1 | coding | downstream | 31277 | 34652144 ~ 34656745 (-) |
| XLOC_026580 | NA | coding | downstream | 46049 | 34641048 ~ 34641973 (-) |
| XLOC_026579 | tac4 | coding | downstream | 63277 | 34623560 ~ 34624745 (-) |
| XLOC_026578 | zgc:163143 | coding | downstream | 74921 | 34601852 ~ 34613101 (-) |
| XLOC_026577 | nmrk1 | coding | downstream | 88360 | 34597741 ~ 34599662 (-) |
| XLOC_026583 | nsfa | coding | upstream | 13384 | 34766989 ~ 34801041 (-) |
| XLOC_026584 | psmd11a | coding | upstream | 47541 | 34801146 ~ 34816979 (-) |
| XLOC_026585 | NA | coding | upstream | 193797 | 34947402 ~ 34948061 (-) |
| XLOC_026586 | ndufab1b | coding | upstream | 781516 | 35535121 ~ 35541381 (-) |
| XLOC_026587 | dctn5 | coding | upstream | 797265 | 35550870 ~ 35554809 (-) |
| XLOC_026572 | NA | non-coding | downstream | 546841 | 34139637 ~ 34141181 (-) |
| XLOC_026558 | BX649502.11 | non-coding | downstream | 601539 | 34086041 ~ 34086483 (-) |
| XLOC_026547 | BX649502.5 | non-coding | downstream | 623086 | 34063955 ~ 34064936 (-) |
| XLOC_026544 | BX649502.10 | non-coding | downstream | 629305 | 34058679 ~ 34058717 (-) |
| XLOC_026588 | NA | non-coding | upstream | 811523 | 35565128 ~ 35574451 (-) |
| XLOC_026600 | NA | non-coding | upstream | 1566634 | 36320239 ~ 36323625 (-) |
| XLOC_026606 | NA | non-coding | upstream | 1829495 | 36583100 ~ 36587136 (-) |
| XLOC_026612 | FO744883.1 | non-coding | upstream | 2002428 | 36756033 ~ 36756149 (-) |
