XLOC_026599 (prkar1aa)


Basic Information

Item Value
gene id XLOC_026599
gene name prkar1aa
gene type coding
species zebrafish (Danio rerio)
category of species model fish

Chromosome Information

Item Value
chromosome id NC_007114.7
NCBI id CM002887.2
chromosome length 62628489
location 36262593 ~ 36272670 (-)
genome version GRCz11_2017_zebrafish_Genome

Sequence

>TCONS_00051821
GAGTAAAGCACGTCGACAAACTCCTCGAAGCGACTCAGGTCATCATGGCGTCCAGCAGTACGAGCAGTGAAGAAGAGAGGAGCTTGCGGGAGTGTGAGCGCTACGTGCAGAAGCACAACATCCAGCAGCTGCTGAAGGACTGCATTGTGCAGCTGTGCACCGCCAGGCCTGAAAGACCCATGGCTTACCTCAGAGACTACTTCGAGAAGcttgagttgGAGGAGGCTAAACAGATGGTGAGCCAGCAGAAGTCCAGCTCTCGCTCAGATTCTCGGGAAGATGAGGTCTCTCCTCCTATGAACCCTGTGGTTAAAGGCCGACGGCGCCGTGGTGCCATCAGTGCAGAGGTCTACACTGAGGAGGACGCCACTTCTTATGTCAGAAAGGTCATTCCTAAAGACTACAAAACTATGGCTGCCCTTGCTAAAGCAATTGAAAAGAATGTTCTTTTTGCTCATCTTGACGACAATGAAAGAAGTGACATATTTGACGCCATGTTCTCAGTCACCTACATTGCAGGGGAGACTGTCATTCAGCAAGGGGATGAAGGAGATAATTTTTACGTTATTGATCAAGGTGAAATGGATGTGTATGTGAACAATGAGTGGGTGACCAGTATTGGAGAAGGTGGCAGTTTTGGTGAACTGGCTTTAATCTACGGCACTCCTAGAGCAGCCACTGTCAGAGCAAAGACCAATGTCAAGCTGTGGGGCATTGACAGAGACAGCTACAGGAGAATACTCATGGGAAGTACTTTAAGAAAGAGGAAAATGTATGAGGAATTCCTTAGCAAGGTGTCCATTTTGGAGTCTCTGGATAAATGGGAACGATTGACAGTCGCTGATGCACTTGAGACAGTCCAGTTTGAAGATGGCCAGAAGATTGTGGTGCAGGGTCAACCAGGAGATGAGTTCTTCATAATTCTTGAGGGCTCGGCTGCGGTCTTGCAACGGCGGTCGGAGAATGAAGAATTTGTGGAGGTTGGAAGACTCGCACCGTCTGACTACTTCGGAGAGATCGCTCTGCTCATGAACCGTCCTCGTGCTGCCACCGTGGTTGCCCGCGGCCCGCTGAAGTGTGTAAAACTCGACCGTCCTCGGTTCGAGCGTGTGCTCGGCCCCTGCTCAGATATCCTGAAGAGAAACATCCAGCAGTACAACAGCTTCGTATCTCTGTCGGTCTGAGGCGCTCGCCAGGCTCTTTCCTCCTCTATTGCAGGGTCCACCAATGCAAATCCGCTTTATTTTCGTACTTTTCTTTATGCATTTTTCCAACACCCAGGTGCCCATTTACTTCAGtgttctctctctgtctgtttttcGATTCGTGCCGTACCCTGTCGCGTCCGTGTCCATCATAGACTCACCGTAAGGCCGATTGTTAGTTTTGCCTGAGAAACGAGCCAATCATTGTGCCACAGATGCCTGTCACCTGAACAGATGTTGAAATAACAAGGTCTATTGGGATGTTTATTTGTTCCACTTGCCTCCAGATTGCTTCACATTTCTGCATAACAGTGTTGGAAGGAAAATAGTGGCAGGATGTAGTGTATCTACTCAGTATATGATGATGCATCTTAATTGAATCATCGCGTTTCACATTCAGTTTTCCCTCATTTATTTCCAGCGTTTAATATAGGGAAGCCAAAGGCATAAATCCATGTTGTTTTTTGGGGGGAACTGAAGTTAAAACATCACCGTGTTTTTCACGGTGATCAGCTTTGCTCTTTTATTGGTATAGCTGCACATATATAGTGtatttatatgattatatattaCAAGTAAATGACCATAACCATATTTTTTGCAcagtttattgtttatatatatatatatatatatatatatatatatatatatatatatatatatatatatatatatatatatgaaaacatGTTCTATGCGCCTGCTGTTTTTCATTGTGGCATTGGATCCCATTGCATTGGGTTTTTCATGTGTTTTTGGATGTTTTGTTCTGCTTTCATTCATGCTACACACAGCTTGCAATGGACTCTTATGTTGAGCAGATCAAGATGACTCGAATCTGCTTTCACGTCTTCTTCTTtcttaaaaactgcttatatttgtttgtttccccCACAATGTTTTTATGGTGGgagtatatatttgtttaattgttcAGAAATGTAATGGTTAATGCAATCTGAATCTTTGTTAAGAGAGAATTCGACAGGAAGTGAGTGTTTGGTGACCTCCTTGGCCAACTGAGATCCATtaggttgttttttttctatgtgAGTTTGTGTGAACTGCTTCGTTTTTCCCgtttatttcttctttctttgatgttttaaatttttaaatcaaaatattctGTGCAGGACTAAGAAGAATAGTTTTCATATGATCAGTGTCCTGTTTAGATGGAGATTTCAATTTTTCAGCTTCTAGTTTAATGAAAGTCTTAAAACAGGGACAGTATTTACCGTTTATGGTGTCTGTATGCCATTAGGGAAGGGATCCATCAAATGTTTGGGATTAAATTCCCGATCCACTGCCGCCACCAATTTAATCATTGATCAGAATATTGTTCTTAGGGTTCTCTGAGTTTTACCAGGTGGTTCAATAGTGTTAACAGTTGCTGAAGGTAGATTTTAATCATTGTCACTCAGAGATACTCTTgtattatttgaatatatttgatGTGAGTTTTCATTTTGTGTATTTGTTTCCTGCACATCTTGTGTTATGTAATTATGCAGATGTCCGATTCCTTTATACCACACAGACTCATGATATTGGAAGCAAGTTTAGGTTTTGAAAAGTGCCTGATTTCTTTACTCTCATACCGCATAGCTAATCTCTCGCAGTAATTTTCCCTCTGATATATTCATACACCATACTTGTGTCctgtattatttataaacaataatattttgtttcattGATATATCCAAATTCTCTTTTGCAATGTATTTTATTCAGACTTAAAGCTCCAGTAAATAAAAAGTTTGCACAGAACTGTCTCACAATTGCTGTTAATTAAAGAGAGTTGCACGTGAACAACtttatttagtgtatttttatttgtctcCTCTACATGGGAcagttgttttctttttattttctgacACTTGTTTTTAGGGACTGTCGGTGCAGCGTGCATGAAAATGTTTCTGACATCCACAAAATTCTGCCCCAGACTGGATTGGAATTTAAAATCAGTCAAATAATGGTGCTGTAGCTTTCAAAACAGATTTTGCACCCTTAATTTCATGGGATGTGACCTTTCAAAAAGCCTTTTGATTAACTGTTTCAACTGTCTTTTTAATGAGTGGATTATGGCTTATAATGGggtttaattaaatgtgtttaaattgatATTACTACAGCATGAGTTCTTAATAATGAACTGTGAACCCCTTTGATAGGCTAAATACTCTACATGTTATCGCTCATTTATGTTTAACTTCATTTGGCAGTGCGGAATTGACAAAGGAAGCATAAATATTTTGATGGTTTCtgtaaaatgcataaataaaaacccTTTTATAAATATGATTTAGTTCCACCACATTTTCTGCTTGCTACACCCTGTTTCTTGAAGAACATTCAGCGGTACACTGGAAATGTGTTTGTATTAGCAACCTTTACCTTTGTTAAAATTTGTTTTCAGTAGCTTGCTTTTCTTGCCCTGGTTGTGACTGCCGGTGGTGTTTTCTTCTGGAGCTTTCAGTAAATCTGTGTTCTAGTATGTACAGAGGATTGATATATATTTGCTTATAAGCTTTGCCTTCAGGGCTTAGAGACTCCTGTTCACCCATTCTTCAGTACATTAAACCCTCAATACAGAGAGTTGTAAAATGTCAGAGGACCATTTTCTATTATTCTTTTTCTATAACTGTATCCGGTTTGATTTCATTGGATGTGCTCAAGTTGTAAACCTTTTGGTATAGATTGTCCCAATGGCAGGTCaagcaataaaatgattaattcttGAA

Function

symbol description
prkar1aa Predicted to enable cAMP binding activity; cAMP-dependent protein kinase inhibitor activity; and protein kinase A catalytic subunit binding activity. Predicted to be involved in negative regulation of cAMP-dependent protein kinase activity. Predicted to act upstream of or within phosphorylation and regulation of protein phosphorylation. Predicted to be located in plasma membrane. Predicted to be part of cAMP-dependent protein kinase complex. Predicted to be active in cytoplasm. Is expressed in early embryonic cell; immature eye; neural tube; and somite. Human ortholog(s) of this gene implicated in Carney complex; acrodysostosis; and primary pigmented nodular adrenocortical disease. Orthologous to human PRKAR1A (protein kinase cAMP-dependent type I regulatory subunit alpha).

GO:

id name namespace
GO:0043949 regulation of cAMP-mediated signaling biological_process
GO:0010738 regulation of protein kinase A signaling biological_process
GO:0016310 phosphorylation biological_process
GO:0001932 regulation of protein phosphorylation biological_process
GO:0005952 cAMP-dependent protein kinase complex cellular_component
GO:0016740 transferase activity molecular_function
GO:0000166 nucleotide binding molecular_function
GO:0030552 cAMP binding molecular_function
GO:0008603 cAMP-dependent protein kinase regulator activity molecular_function
GO:0016301 kinase activity molecular_function

KEGG: NA

ZFIN:

id description
ZDB-GENE-050116-2 Predicted to enable cAMP binding activity; cAMP-dependent protein kinase inhibitor activity; and protein kinase A catalytic subunit binding activity. Predicted to be involved in negative regulation of cAMP-dependent protein kinase activity. Predicted to act upstream of or within phosphorylation and regulation of protein phosphorylation. Predicted to be located in plasma membrane. Predicted to be part of cAMP-dependent protein kinase complex. Predicted to be active in cytoplasm. Is expressed in early embryonic cell; immature eye; neural tube; and somite. Human ortholog(s) of this gene implicated in Carney complex; acrodysostosis; and primary pigmented nodular adrenocortical disease. Orthologous to human PRKAR1A (protein kinase cAMP-dependent type I regulatory subunit alpha).

Ensembl:

ensembl_id ENSDARG00000076128

RNA

RNA id representative length rna type GC content exon number start site end site
TCONS_00051821 True 3964 mRNA 0.40 11 36262593 36272670

Neighbor

gene id symbol gene type direction distance location
XLOC_026598 rac3a coding downstream 2491 36248851 ~ 36260102 (-)
XLOC_026597 gps1 coding downstream 15618 36234060 ~ 36246975 (-)
XLOC_026596 csnk1da coding downstream 52249 36173203 ~ 36210344 (-)
XLOC_026595 BX897685.1 coding downstream 90625 36170943 ~ 36171968 (-)
XLOC_026594 engase coding downstream 109002 36136530 ~ 36153591 (-)
XLOC_026600 NA coding upstream 47569 36320239 ~ 36323625 (-)
XLOC_026601 gna13b coding upstream 59909 36332579 ~ 36364903 (-)
XLOC_026602 cog1 coding upstream 128435 36401105 ~ 36420397 (-)
XLOC_026603 rogdi coding upstream 155318 36427988 ~ 36440705 (-)
XLOC_026604 glyr1 coding upstream 168636 36441306 ~ 36458165 (-)
XLOC_026588 NA non-coding downstream 688142 35565128 ~ 35574451 (-)
XLOC_026585 NA non-coding downstream 1314532 34947402 ~ 34948061 (-)
XLOC_026580 NA non-coding downstream 1620620 34641048 ~ 34641973 (-)
XLOC_026572 NA non-coding downstream 2121412 34139637 ~ 34141181 (-)
XLOC_026558 BX649502.11 non-coding downstream 2176110 34086041 ~ 34086483 (-)
XLOC_026606 NA non-coding upstream 310430 36583100 ~ 36587136 (-)
XLOC_026612 FO744883.1 non-coding upstream 483363 36756033 ~ 36756149 (-)
XLOC_026617 NA non-coding upstream 680955 36953625 ~ 36954088 (-)
XLOC_026618 CT573704.1 non-coding upstream 695201 36967871 ~ 36967993 (-)

Expression


Co-expression Network

Homologous

species gene id symbol gene type chromosome NCBI id location
grasscarp (Ctenopharyngodon idella) CI01000046_06980879_06985344 PRKAR1A.S, PRKAR1AA, PRKAR1AB, PRKAR1A, PRKAR1B.S coding CI01000046 null 6979911 ~ 6986604 (+)
mexican tetra (Astyanax mexicanus) G307150 prkar1a,prkar1aa,LOC107721504,LOC107654492,LOC108274040,LOC107590390 non-coding NW_019172846.1 APWO02000057.1 970157 ~ 1044317 (-)