LOC110531644 (mettl3)


Basic Information

Item Value
gene id LOC110531644
gene name mettl3
gene type coding
species rainbow trout (Oncorhynchus mykiss)
category of species economic fish

Chromosome Information

Item Value
chromosome id NC_048573.1
NCBI id CM023227.2
chromosome length 79455637
location 17339272 ~ 17346251 (+)
genome version USDA_OmykA_1.1_2020_rainbow_trout_Genome

Sequence

>XM_036987487.1
GGTGAACAATTCTACTTGCAATAGAAAAGTTAGCTGTTAAGCTGTTAGATTTTGGATGTGTCTGTCTTGGTGGTTTCCTCCAACAACAAGGGGGAACCAGTCATTCGTTGTTGTTGCTAGTCCGACACAGTGCGAGCGGTGTCCACATTATCCCGCTAAACTAAGTGATCTTGCATGCCCCGTTTTCGATTCACTTTCGCGGTAGCTCCTACTCTAAATGTCGGATACATGGAGCAACATCCAGGCACACAAGAAGCAGCTGGACTCGCTGCGAGAGAGACTGCAGAGGCGACGGAAAGACCCCACGCAACTCGCTGCAGAGGTGGGAGGCAGCAGTACTGAAGGGGCTGCAGCGCGGAGTGAGAGTCCAGGACCAGCCCTCCAGAGTCCCCCACAGGAGGAGGCTGAACGTCCCCCGGACCCTGAACTAGAGAAGAGACTCCTGGGTTATCTTTCGGACCTGAGCCTCTCACTGCCCACTGACTCCTTGACCATTACTGATGAGCTCAGTACTTCTGAAGTGCCTGTCACCCATGGCTGCATCCAGAGTCTGCTGCTCAAGTTCTCTGCCCAGGAGCTCATCGAAGTCCGGCAGCCATCCGTggccacctccccctcctcttcttcctcaacACTCGTCATCTCCGTGGACCACACAAAACTCTGGGCCATGATTGGGGGCGGGGCCTTAGGCCAGAGGAAGAGGAAAGCAGAGGACCAAGCCCACCATAAACGTCCGCCAGGTTCCTCCCCTGCTCTCCAGAGCCCGCCCTCCCCTCCGCCcacttcctccatctccctgGCACCTGCTTCCTCCTCCCAGCTGACCGGGCCCTCTGATTGGAAGGCTGGAGGAGGAAGGGGCGGGGCAGATAAACAGGGCAGGACCAGTAAGGGGCAGACGTCTCACCTGGACATGGAGATAGAGAGCCTCCTGAACCAGCAGTCCACCAAGGAGCAGCAGAGCAAGAAGatgAGCAGAGAAATCCTGGAGCTTCTGAACACCAGCACAGCTAAAGAGCAGTCCATCGTTGAGAAGTTCCGCTCACGCGGTCGTGCTCAGGTCCAGGAGTTCTGTGACCATGGGACCAAAGAGGAGTGTACGCGGTCTGGGTTCACACCCCAGCCCTGCACCAAGCTGCACTTCCGacGCATCATCAACAAGCACACAGACGAGAGTCTTGGAGACTGCTCCTTCCTCAACACCTGTTTCCACATGGACACCTGTAAATACGTGCACTATGAGATCGACGCCCCTCCAGAGGCAGAGGGGGGCCTGATGGGGACCCAGGCTGGGGGCATGGAGGTGGGACTACACCAGGGGGAGGAAGACAGCAACGTGGGGAAACTATTCCCCTCTCAgTGGATCTGTTGTGACATCCGGGTCCTGGACGTGTCGATTCTGGGGAAGTTCTCTGTTGTGATGGCCGACCCTCCCTGGGACATCCACATGGAGCTGCCCTACGGGACTCTAACGGACGACGAGATGAGGAAGCTCCACATCCCCGTCCTCCAGGACGACGGCTTCCTCTTCCTCTGGGTGACTGGCAGGGCTATGGAGTTGGGTAGAGAATGTCTGAGTCTTTGGGGCTATGAGCGTGTTGATGAGATCATTTGGGTGAAGACCAACCAGTTACAGAGAATCATCCGTACCGGGAGGACTGGTCACTGGCTCAATCATGGGAAGGAGCACTGCTTGGTGGGCGTGAAGGGGCAGCCCCAGGGATTCAACAGAGGGCTGGACTGTGATGTCATCGTggcagaggtgcgTTCCACCAGCCACAAGCCAGATGAGATTTATGGAATGATTGAGAGACTCTCACCTGGTACCAGgaagattgagctctttggcagACCTCACAATGTCCAACCCAACTGggTAACTCTTGGTAATCAGTTAGATGGCATTCACCTCTTGGACCCTGATGTCGTGGCTCGCTTCAAGAAACGTTACCCAGACGGAGTCATCTCCAAACCCAAGAACATGTAGAGAGTGGTCCTAAACGCCTTCCATGGGGTCATCGTTGTCAATTACTTGTCCTGTTATAAACatgttatgtcatgttatgtcACGTTATGAACTTAGACGCCGAGGGAAAAACACTGATCAATGATCAGTAAGTGTCTGATGGACTGCCTTctgttttttatgtatttttttgtaccaatTACAACATTTTGTAATAAATATGGTTGAAGGACTATTTATGAATCTCTATGATGCGGATCAGACATACTGCACAATGAATCCACCAAAAACATTTCAGTATATCCTTTTTTTGTATTACTTTGTTAGTACATTTTGTCCATTTCCATGACAACAGCACTACAGTATACAAAGTGAGGACTGGCTAGTTTGGGAATCTTGATTGATTGACATTTACTTTGATTAAAAGAAAAACATTGACATTGGAAATGTATCAATATTTTCTTCACAGTAATTAGGAATCACATTTTTCTCATCATTCCAAACGTACCACCGTAGCCCCAGATGTATGCTACTACGTTCTCGTAcaatcattttcacaatttgtACAAAAATATATGATGAGTATTTATTATCCCTAAACTAGTAGGTGAAGCAGGGAAAATATTTCAATGTTTAGAGAGGGTGGGTTGTAGAACCCAACTAAAGCACCAAAACACTGTTGAAATGTCTTCCAGAACAATCTGTTGACTTTCTCCTCCATTCACTGATGCTCCCCATAAGATGCCATCAGAAGTAAAGAGCTGCACGTAAGCTGGAGGAGCTGCCGGTTAACATGTCTAGATATGAATAAAGTGTAGATGCATTCCAAGCAGCCAGTGGAAAAGGGAACTAGAAGAAGACAGCCAGCACCAAACTGAATTTAATTGAGGAAATGTTCAAAAAGTAAGTAAAAAGGCACAAACTCATTAGTATCTTCATCAGCCAAACCAATCAAAATCTAGTTACCATGTTTTTCTCAGCAAGTTAGGATAGTGTCAGGATAAGAACAAAAAAGCCTGTATTTAAAGTTGGGAGTGCCAAATTGTCTTGTTGTATTCAACAGCTAGTATTTTAAAGACTTGAATTTGCAGTTGTGGTCTtttacctgcccccccc

Function

symbol description
mettl3 Enables mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity and mRNA (N6-adenosine)-methyltransferase activity. Involved in endothelial to hematopoietic transition and regulation of hematopoietic stem cell differentiation. Acts upstream of or within several processes, including Notch signaling pathway involved in arterial endothelial cell fate commitment; hematopoietic stem cell proliferation; and oocyte maturation. Predicted to be located in cytoplasm. Predicted to be part of RNA N6-methyladenosine methyltransferase complex. Predicted to be active in nuclear speck. Is expressed in several structures, including gill; heart; liver; nervous system; and pleuroperitoneal region. Used to study infertility. Orthologous to human METTL3 (methyltransferase 3, N6-adenosine-methyltransferase complex catalytic subunit).

NR:

description
N6-adenosine-methyltransferase 70 kDa subunit

GO:

id name namespace
GO:0080009 mRNA methylation biological_process
GO:0005634 nucleus cellular_component
GO:0016422 mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity molecular_function

KEGG:

id description
K05925 METTL3; mRNA m6A methyltransferase catalytic subunit

RNA

RNA id representative length rna type GC content exon number start site end site
XM_036987487.1 True 3085 mRNA 0.49 11 17339272 17346251

Neighbor

gene id symbol gene type direction distance location
LOC110532942 LOC106577806 coding upstream 33643 17292470 ~ 17305629 (+)
LOC118966009 NA coding upstream 70238 17266030 ~ 17269034 (+)
LOC118966167 NA coding upstream 73855 17254266 ~ 17265417 (+)
LOC118966176 NA coding upstream 96722 17240870 ~ 17242550 (+)
LOC118966008 NA coding upstream 116872 17202617 ~ 17222400 (+)
LOC110531656 pop7 coding downstream 841487 18187738 ~ 18190442 (+)
LOC110531658 LOC106577765 coding downstream 904681 18250932 ~ 18256403 (+)
LOC110531660 LOC106608810 coding downstream 955117 18301368 ~ 18320759 (+)
LOC110531663 LOC106577697 coding downstream 1294404 18640655 ~ 18648675 (+)
LOC110531664 LOC106577696 coding downstream 1309926 18656177 ~ 18673318 (+)
G776483 NA non-coding upstream 8483 17330339 ~ 17330789 (+)
G776519 NA non-coding upstream 9949 17328963 ~ 17329323 (+)
G776516 NA non-coding upstream 17482 17320610 ~ 17321790 (+)
G776508 ylat1 non-coding upstream 23693 17305781 ~ 17315579 (+)
G776478 NA non-coding downstream 7837 17354088 ~ 17354428 (+)
G776524 NA non-coding downstream 8981 17355232 ~ 17452622 (+)
G776477 NA non-coding downstream 18734 17364985 ~ 17369335 (+)
G776530 NA non-coding downstream 25520 17371771 ~ 17373560 (+)
G776555 NA non-coding downstream 143060 17489311 ~ 17490326 (+)
G775945 NA other upstream 655781 16683194 ~ 16683491 (+)
LOC110532939 NA other upstream 996462 16315734 ~ 16342810 (+)
LOC110532936 LOC106577844 other upstream 1088408 16233342 ~ 16250864 (+)
G775306 NA other upstream 1151822 16186276 ~ 16187450 (+)
G776487 NA other downstream 34374 17380625 ~ 17394121 (+)
G776818 LOC106600668 other downstream 311946 17658197 ~ 17659145 (+)
G777111 NA other downstream 655638 18001889 ~ 18002182 (+)
G777113 NA other downstream 657016 18003267 ~ 18005668 (+)
G777165 NA other downstream 761768 18108019 ~ 18108482 (+)

Expression


Co-expression Network