XLOC_026629 (baxa)



Basic Information


Item Value
gene id XLOC_026629
gene name baxa
gene type coding
species zebrafish (Danio rerio)
category of species model fish

Chromosome Information


Item Value
chromosome id NC_007114.7
NCBI id CM002887.2
chromosome length 62628489
location 37766473 ~ 37773800 (-)
genome version GRCz11_2017_zebrafish_Genome

Sequence


>TCONS_00051880
ATTCACATTTCCGCCGCCCAATGAAATCTCCCAGAAATCTTTTTAATAACGCGTTCTCGCTCACTCAGTCACAGTTTTCATCATACTGCTGACATGGAAGCGCTGTTGGATTACGTTGTTCGTATTGgCAGTGGCAATGATCAGACACTTGATGCAGGATCTGCAGTTCTCTTTAACTTCATCTTTGAATGGCTTCATCAACACTTAGACAAAGAAGCTGAAATAACCTGTTGGTTACAAAATAATTTGGGTATTGTTGAGAAAAGTGACCCCAGCCATAAAGATGCAATCGAGTGTATGGTGAGGATTGCAAATGAAATGGAAGGAAATGAAGAACTACAAGGgaTGTTAAATAGCGCTCTCTTAAATCCAACTCTAGAACACTACATCCTTGTGGTCAATGGGACCTTCTCTGATGTGACATTAAGCTGGGGTAGTGTTGTGGCACTTTTTTATGTTGCATGTCGGTTTGTTGTTAAGGCTGCTGAAATCAACTCTGTTGACTTGGTCAGAAGCATTATAAACTGGACTATGCCTTTTATTAGAAAGACCTGCATTTTAACCTGGATCAGGGAACAGGGTGGATGGGGCGCAATCCGCTCATATTTCGGGACCCCCACCTGGCAGACAGTTGGAGTTTTCCTTGCTGGAGTTCTTACTGTAGGCTTGGTGCTCTACAAAATGTGAACCCGAGGATGACAAAGTGGAATAACAGAGAGTCGAGACATTGAGGCTGAAACAGACCAGCAAAATATAATGGAAGGATAAGGGTGAAGAGAAAGTTGAAAAAAGAAAGATGACACATTGTCTCAAGCCACTTTTGTTACCCCTATTCTTCTGCTgtgattattttgctttttaaatcttGAACAATTATgtcttttaattaaatatttaattttaaaatttgcacatttacACCAAGGAATGCATGGGTGATTCAGAGTTAGGCTTAATTTTggccatttatttttttatttggaacAGGTTTCATGGTATTTTTATTACTAATGCCAAAGCGTCATCTATCATTAAtctttttacataattttaattCTTTGAAAACCTTTTAAACTTTTCTAGGCTTTTCACGAAAATAAAACAAGCTAATCTGCAGACCATGCAGACAAAAAGTTGATTATTCAAACTGCTCTTAAATAATTTGCAAACAAATGAATCACAAAGGCTGTATCTCCATAAAACATGTGTGTAATGACGACCATAACATCCAGTGGTCAGTCTTTAAAAAGAACAACCAGCCAATCAGGCTACAGTATGTGGGAGTGTCTTGGCAAGAACGTCCTATAACAGGAAAGGACAGAACTAGTgacctaaaataatttttaacttcACTAAGCCACGCTGATACTTTTTACACAAATAAATCATTTCCTTTTTGATTACTGAAAGAGCCAGTGAAACTTTCCAAAGCAGATTCATTTCTCATCTGGGATTTAATAAAACACAGGTAGTTTGGCTGGAACTAGTGCAAAGAATGAGTAAGAGTTAGTCAAGAGGTCCAGACCTGACAAACAGATGATATGAGCTCTTCCCCTTAGCAAAGGGGTACTGTAGTACTGTATTTTCACCATTGTAAGTCAGACCTATAATCTGAACTTTTTTATTCTATGTATTTTTTGGTCTATGTAATATGAGCCCAtgagtttgttttgctttgtttttgtacgaataaataaatacttttttcacatattaaaaa
>TCONS_00051881
ATTCACATTTCCGCCGCCCAATGAAATCTCCCAGAAATCTTTTTAATAACGCGTTCTCGCTCACTCAGTCACAGTTTTCATCATACTGCTGACATGGAAGCGCTGTTGGATTACGTTGTTCGTATTGgCAGTGGCAATGATCAGACACTTGATGCAGGATCTGCAGTTCTCTTTAACTTCATCTTTGAATGGCTTCATCAACACTTAGACAAAGAAGCTGAAATAACCTGTTGGTTACAAAATAATTTGGGTATTGTTGAGAAAAGTGACCCCAGCCATAAAGATGCAATCGAGTGTATGGTGAGGATTGCAAATGAAATGGAAGGAAATGAAGAACTACAAGGgaTGTTAAATAGCGCTCTCTTAAATCCAACTCTAGAACACTACATCCTTGTGGTCAATGGGACCTTCTCTGATGTGACATTAAGCTGGGGCTGCTGAAATCAACTCTGTTGACTTGGTCAGAAGCATTATAAACTGGACTATGCCTTTTATTAGAAAGACCTGCATTTTAACCTGGATCAGGGAACAGGGTGGATGGGGCGCAATCCGCTCATATTTCGGGACCCCCACCTGGCAGACAGTTGGAGTTTTCCTTGCTGGAGTTCTTACTGTAGGCTTGGTGCTCTACAAAATGTGAACCCGAGGATGACAAAGTGGAATAACAGAGAGTCGAGACATTGAGGCTGAAACAGACCAGCAAAATATAATGGAAGGATAAGGGTGAAGAGAAAGTTGAAAAAAGAAAGATGACACATTGTCTCAAGCCACTTTTGTTACCCCTATTCTTCTGCTgtgattattttgctttttaaatcttGAACAATTATgtcttttaattaaatatttaattttaaaatt
>TCONS_00051882
AGTTTTCATCATACTGCTGACATGGAAGCGCTGTTGGATTACGTTGTTCGTATTGgCAGTGGCAATGATCAGACACTTGATGCAGGATCTGCAGTTCTCTTTAACTTCATCTTTGAATGGCTTCATCAACACTTAGACAAAGAAGCTGAAATAACCTGTTGGTTACAAAATAATTTGGGTATTGTTGAGAAAAGTGACCCCAGCCATAAAGATGCAATCGAGTGTATGGTGAGGATTGCAAATGAAATGGAAGGAAATGAAGAACTACAAGGgaTGTTAAATAGCGCTCTCTTAAATCCAACTCTAGAACACTACATCCTTGTGGTCAATGGGACCTTCTCTGATGTGACATTAAGCTGGGGTAGTGTTGTGGCACTTTTTTATGTTGCATGTCGGTTTGTTGTTAAGGTGAAAACATATCCATGTATCATCTcatattaagggtgctttcacacttggttcaattgcctggactgtacccaagttcgattgtccccccttgccacctttttaattggtttgtgttcacactgtctctttccttctgaaccctggtaCACTTGcttcatcgagctgctgttttgtttacggctgtTGCAAGGTGACGTCACGAAAGCAAAGCATGACATCgcagtcattctgcttttactgaatcttttggttttacaCATACAGAAAGCGACACACGTCCACGTttagaacatcacacagtgtctgcagaagctgtttttgga

Function


symbol description
baxa Predicted to enable channel activity; protein heterodimerization activity; and protein homodimerization activity. Acts upstream of or within several processes, including positive regulation of cysteine-type endopeptidase activity involved in apoptotic process; response to cadmium ion; and response to methylmercury. Predicted to be located in membrane. Predicted to be integral component of membrane. Predicted to be active in mitochondrial outer membrane. Is expressed in several structures, including digestive system; female organism; heart; immune system; and male organism. Human ortholog(s) of this gene implicated in acute lymphoblastic leukemia; ataxia telangiectasia; colon adenocarcinoma; and colorectal cancer. Orthologous to human BAX (BCL2 associated X, apoptosis regulator).

GO:

id name namespace
GO:0042981 regulation of apoptotic process biological_process
GO:0043280 positive regulation of cysteine-type endopeptidase activity involved in apoptotic process biological_process
GO:0043065 positive regulation of apoptotic process biological_process
GO:0001836 release of cytochrome c from mitochondria biological_process
GO:0097192 extrinsic apoptotic signaling pathway in absence of ligand biological_process
GO:0046686 response to cadmium ion biological_process
GO:0051597 response to methylmercury biological_process
GO:0008630 intrinsic apoptotic signaling pathway in response to DNA damage biological_process
GO:0008053 mitochondrial fusion biological_process
GO:0016020 membrane cellular_component
GO:0016021 integral component of membrane cellular_component
GO:0005741 mitochondrial outer membrane cellular_component
GO:0015267 channel activity molecular_function
GO:0042803 protein homodimerization activity molecular_function
GO:0046982 protein heterodimerization activity molecular_function

KEGG: NA

ZFIN:

id description
ZDB-GENE-000511-6 Predicted to enable channel activity; protein heterodimerization activity; and protein homodimerization activity. Acts upstream of or within several processes, including positive regulation of cysteine-type endopeptidase activity involved in apoptotic process; response to cadmium ion; and response to methylmercury. Predicted to be located in membrane. Predicted to be integral component of membrane. Predicted to be active in mitochondrial outer membrane. Is expressed in several structures, including digestive system; female organism; heart; immune system; and male organism. Human ortholog(s) of this gene implicated in acute lymphoblastic leukemia; ataxia telangiectasia; colon adenocarcinoma; and colorectal cancer. Orthologous to human BAX (BCL2 associated X, apoptosis regulator).

Ensembl:

ensembl_id ENSDARG00000089129

RNA


RNA id representative length rna type GC content exon number start site end site
TCONS_00051880 False 1720 mRNA 0.37 6 37766473 37773800
TCONS_00051881 False 861 nonsense_mediated_decay 0.40 6 37767285 37773800
TCONS_00051882 True 734 lncRNA 0.42 4 37771677 37773728

Neighbor


gene id symbol gene type direction distance location
XLOC_026628 si:dkey-260c8.6 coding downstream 6477 37757385 ~ 37759996 (-)
XLOC_026627 gpatch8 coding downstream 66481 37662444 ~ 37699992 (-)
XLOC_026626 NA coding downstream 117084 37634100 ~ 37649389 (-)
XLOC_026624 arf2a coding downstream 177618 37558491 ~ 37588855 (-)
XLOC_026625 NA coding downstream 181666 37581522 ~ 37584807 (-)
XLOC_026630 baxa coding upstream 2689 37776489 ~ 37785873 (-)
XLOC_026631 BX936420.1 coding upstream 752179 38525979 ~ 38529416 (-)
XLOC_026632 mpp3a coding upstream 874187 38647987 ~ 38692920 (-)
XLOC_026633 si:ch211-198m17.1 coding upstream 931625 38705425 ~ 38745598 (-)
XLOC_026634 znf281a coding upstream 989091 38762891 ~ 38783951 (-)
XLOC_026621 CT573704.2 non-coding downstream 690660 37075698 ~ 37075813 (-)
XLOC_026619 NA non-coding downstream 794251 36969403 ~ 36972222 (-)
XLOC_026618 CT573704.1 non-coding downstream 798480 36967871 ~ 36967993 (-)
XLOC_026636 NA non-coding upstream 1197635 38971435 ~ 38975698 (-)
XLOC_026637 NA non-coding upstream 1338514 39112314 ~ 39113547 (-)
XLOC_026646 CU464118.1 non-coding upstream 1598073 39371873 ~ 39454903 (-)
XLOC_026648 NA non-coding upstream 1787984 39561784 ~ 39563301 (-)

Expression



Co-expression Network