XLOC_026662 (top3a)


Basic Information

Item Value
gene id XLOC_026662
gene name top3a
gene type coding
species zebrafish (Danio rerio)
category of species model fish

Chromosome Information

Item Value
chromosome id NC_007114.7
NCBI id CM002887.2
chromosome length 62628489
location 40235288 ~ 40254634 (-)
genome version GRCz11_2017_zebrafish_Genome

Sequence

>TCONS_00051927
CAGGCGCCGAAATTGGAAGTTTTTAGTGTTGTTACCTTCGTTGTGATCACAGTTTTACAGATTTACTTTCCGATTGggttcaaatgtttttatttcagttaacgaccaAGTTGTTAGTGTTTTTATGCTAGTTTGGACGCTGTTCATTTGATGTAATGTCCGGAGTGCACCGTGATCATGCGCCGTTAGGTCACAGTTATGAACGTTTTGTTTAGGGCACTAAGAAAAACTGTCAACAGTCGATTTTATAGACATATATCTGTAAGCATGATAAGACGCACTCAGATTAAGAAAGTGCTGTGTGTGGCCGAGAAAAACGATGCAGCTAAAGGCATAGCAGAGATCATGTCAAATGGCAGATCCAGAAGAAGAGAAGGCTGCTCTGTTTACAACAAAATATATGAGTATGAATACAACCTGTTCGGCCAAAATGTTACTGTAAACATGACGTCAGTATCAGGGCATCTCTTGGCTCTTGAATTCAAAGCTCCTTTTCAGAAATGGCATAGTTGTAGTCCAGTCCTATTGTTTGATGCTGAGGTGGAAAAGTACTGCCCTGAGAACTTTATACCGATTAAGAGGACTTTGGAGAGAGAGGTGAGGCAGTGTCAAGCTCTGATTGTTTGGACTGATTGTGACAGGGAAGGAGAGAATATCGGCTTCGAGATCATTGATGTCTGCAAAGCAGTGAAGCCAAACATCCAGGTCTTCCGTGCACGGTTCTCTGAGATCACCCCAAACTCCATTAGGAGAGCCTGTGAGACCCTCACGGAGCCTGATATCAATGTTAGCGATGCGGTCGACGTGAGACAGGAGCTAGATCTTCGCATTGGGGCATCGTTTACCAGATTCCAGACTTTGCGCCTGCAGAAGATATTCCCAGAATCTCTCTCTGATCAGCTCATCAGTTATGGCAGCTGTCAGTTCCCCACTCTTGGCTTTGTGGTAGAACGATTTAAAGCCATTCAAGCCTTCATCCctgaaacattcttcaaaatcaaAGTTGTCCATGAACCTAATGAAGAGGAGTCAGTGGAATTCAACTGGAAAAGACATCGACTGTTCAATCACACCGCATGCCTTGTGCTGTATCAGATGTGCATGGAGGAACCCATGGCGAAAGTTATATCTGTAACAAGTAAACCAAAAAGCAAATGGCGACCTTTACCACTGGACACTGTGGAACTTGAAAAACTGGCCTCCAGAAAATTGAGGATAAGTGCCAAAGAAACCATGAAGATTGCAGAAAAGCTGTATACTCAAGGTTTTATCAGTTATCCTCGCACGGAGACCAACATGTTTCCACAGAACCTGAACCTTACCCGTCTGGTTGAGCAACAGACACAGGACCAAGAATGGGGAAATTTTGCCCAGCGTATTTTGGAAAGCGGTGGGCCCACTCCTCGAAACGGAAACAAATCAGATCAGGCCCATCCCCCCATTCACCCCACCAAATACACCAACGGTTTACAGggaaATGAAAAGAGACTTTATGAGTTCATTGTACGTCACTTCCTGGCCTGTTGCTCCAAAGATGCTCAGGGTCAAGAGGTCACAGTCGAAATTGATATAGCGGAAGAGAGATTCTCTGCTAGCGGACTGACGATCATCGCTCGCAATTATCTGGAAGTGTACCCTTATGACAAGTGGTacaataagGTGATTCCATCATACAGCCCTAACACCACATTCCAGCCCACAGCGATTGAGATGGTGGAAGGACAGACCAGTCCACCACAGCTTCTGACAGAGGCAGATTTGATATCACTCATGGAGAAACATGGCATTGGTACCGATGCAACACATGCTGAACACATTGAGACCATTAAGAGTCGCATGTATGTGGGGCTGACGGCAGACCAGAGGTTCCTTCCCGGAGAGCTCGGCATGGGTCTCGTTGAAGGATATAATTCTATGGGATACGAGATGTCTAAACCAGACCTGAGAGCTGAGCTGGAGGCAGACCTTAAACTTGTGTCAGAGGGCCGGAAGAATAAAGCATCTGTCCTCAGTTATCATGTGGCAAAATACAAAGCCGTTTTCATCGAGTCTGTGAGGAAGGCAAAGAAATTAGATGAGGCTTTGTCCAATTATCTGGGTCCGGCTCAGGAGATTGCAGAACAGGAGCAAGTCGAGTTGGAGATACCATTACCTGTGCGAAAGTGTCCTCAGTGTAACCGAGACATGGTGCTGAAGAAGAAGAAAGACAGCACAGGGATGCTTCTTTCATGCTTGGGATATCCAGCGTGTAAAGCAGCCGTGTGGTTTCCTGACACTGTCCTGGAAGTCAGCAGAGACGAGAGCATCTGTCCAACTTGCCGTCCACATCCGGTTCATATGCTGAAGTTTAAATTCAAGAGGGGAAGTTTGCCACCCATGATGCCTCTTGAATTTGTTGGATGCATCGGAGGATGTGATGACACTCTCAGAGAGGTTTTAAACTTGAAATATCTCAGAGGACGTGATGCAGAATCTGCCCCTCAGGCCAATAACAGCTCCAGATCCAGTCAACACCACATTCATAGAACCAGCTCGGCACCTCCTCCATCCAGGGTAGAGAACATTAGACCTCCAGCACCCAGACCTCGAGCTGATCCTGGTCTGCAACCTCCACCTTCAACTCAGGGCGGTGCCATTGTGTGTAACTGTGGTCAGGACGCCTTACTTCTCACCGTGCGCAAAGAGGGTCCCAATCAAGGGCGTCAGTTTTACAAGTGTAACACAGGAGACTGCAAGTTCTTCCTGTGGGCCGATCAGCCACCTGAACAGGGGGTGCCTGAAAGAAACAGAGGGCCTTTAAGTCAAAACGTCCAGCCTCCCAGGCCTTCCAATGGGTTTGGGAATGTCTCACAGCAGAGGCAGAACCACAGAGGGTCTGGAGGCGATGAAGGGGAAACTATGTGTAACTGTAATGAGCCTTCAGTCACCAGGACTGTCATGAAGGAAGGGCCGAACAAGGGCAGAATGTTTCACACCTGCGGGAAACCACGAGATCAGCAGTGTGGCTTCTTCCAGTGGGCCAATGAAAATGTGGCACCAGCCACAGCGTTTTCTGGAGGAAATGGTGGTAAACCATCTGGGAACAAAAAGGCCAGTACTACCTCAGTCAAGCCTCCCACTGCCAAAAGGCAGAGGACCTGTGGAATATGTCATGAGCCAGGACACACCAGAGTCACCTGTCCTCAGGCCCACTGAAAaactaaatttgtaaataaaattaatttgtcttatgcatatttaatgttgttttatgaattgtaaatttgtaatgtagtatgtgtaaaataaagtt
>TCONS_00051928
GCGATGCGGTCGACGTGAGACAGGAGCTAGATCTTCGCATTGGGGCATCGTTTACCAGATTCCAGACTTTGCGCCTGCAGAAGATATTCCCAGAATCTCTCTCTGATCAGCTCATCAGTTATGGCAGCTGTCAGTTCCCCACTCTTGGCTTTGTGGTAGAACGATTTAAAGCCATTCAAGCCTTCATCCctgaaacattcttcaaaatcaaAGGTACTAGTAATTTGCTCACCTAACATTTGATGgcacaatatgtaaaatatttattaaaacaaaaaaacatatacaaaaaaaaactttaatttataaaaaaaaaaaaaacatattgtgtaGATATATATCTAgaaccgcgtctttatttagaggagaagagaagcgaatccggatctccatTTGCAGcagagaaaagctctcgggtaaacaatgtacctttagacacgtaagtta

Function

symbol description
top3a Predicted to enable DNA topoisomerase activity. Predicted to be involved in DNA topological change. Predicted to be located in chromosome. Predicted to be active in nucleus. Human ortholog(s) of this gene implicated in autosomal recessive progressive external ophthalmoplegia with mitochondrial DNA deletions 5. Orthologous to human TOP3A (DNA topoisomerase III alpha).

GO:

id name namespace
GO:0006265 DNA topological change biological_process
GO:0005634 nucleus cellular_component
GO:0005694 chromosome cellular_component
GO:0003916 DNA topoisomerase activity molecular_function
GO:0003917 DNA topoisomerase type I (single strand cut, ATP-independent) activity molecular_function
GO:0003677 DNA binding molecular_function
GO:0008270 zinc ion binding molecular_function
GO:0016853 isomerase activity molecular_function

KEGG: NA

ZFIN:

id description
ZDB-GENE-071212-2 Predicted to enable DNA topoisomerase activity. Predicted to be involved in DNA topological change. Predicted to be located in chromosome. Predicted to be active in nucleus. Human ortholog(s) of this gene implicated in autosomal recessive progressive external ophthalmoplegia with mitochondrial DNA deletions 5. Orthologous to human TOP3A (DNA topoisomerase III alpha).

Ensembl:

ensembl_id ENSDARG00000052827

RNA

RNA id representative length rna type GC content exon number start site end site
TCONS_00051927 False 3292 mRNA 0.47 19 40235288 40254634
TCONS_00051928 True 447 lncRNA 0.38 2 40251416 40251945

Neighbor

gene id symbol gene type direction distance location
XLOC_026661 flii coding downstream 2673 40206031 ~ 40232615 (-)
XLOC_026660 znf598 coding downstream 32681 40185253 ~ 40202607 (-)
XLOC_026659 NA coding downstream 53634 40180136 ~ 40181654 (-)
XLOC_026658 drg2 coding downstream 72421 40153819 ~ 40162867 (-)
XLOC_026656 myo15aa coding downstream 98545 40056485 ~ 40136743 (-)
XLOC_026663 shmt1 coding upstream 6295 40260929 ~ 40276071 (-)
XLOC_026664 pdap1b coding upstream 23070 40277704 ~ 40284744 (-)
XLOC_026665 atp5mf coding upstream 42151 40296785 ~ 40301467 (-)
XLOC_026666 NA coding upstream 141429 40396063 ~ 40405386 (-)
XLOC_026667 actb2 coding upstream 271473 40526107 ~ 40529804 (-)
XLOC_026657 BX649547.1 non-coding downstream 146487 40088685 ~ 40088801 (-)
XLOC_026654 BX649356.3 non-coding downstream 277814 39957358 ~ 39957474 (-)
XLOC_026653 BX649356.2 non-coding downstream 283761 39945865 ~ 39951527 (-)
XLOC_026651 BX322795.1 non-coding downstream 585726 39649445 ~ 39649562 (-)
XLOC_026671 NA non-coding upstream 519784 40774418 ~ 40777723 (-)
XLOC_026680 CR769786.1 non-coding upstream 1057388 41312022 ~ 41312143 (-)
XLOC_026681 BX537310.2 non-coding upstream 1141489 41396123 ~ 41512210 (-)
XLOC_026687 NA non-coding upstream 1928719 42183353 ~ 42205112 (-)

Expression


Co-expression Network