XLOC_026670 (smurf1)


Basic Information

Item Value
gene id XLOC_026670
gene name smurf1
gene type coding
species zebrafish (Danio rerio)
category of species model fish

Chromosome Information

Item Value
chromosome id NC_007114.7
NCBI id CM002887.2
chromosome length 62628489
location 40690212 ~ 40768548 (-)
genome version GRCz11_2017_zebrafish_Genome

Sequence

>TCONS_00051947
GTTAGCCTGTGTTGTTAAGTCTGAAAGCTACAGGGGATTTGCCAGACGGAAATAATACCGTTTTATCGCCGAGAAACACATGCACAGGCCACACGATCGCGTCGCGTGTTTTTATACGTTTTTATATCCTCGTGAAGCGAGCGTCTTGGGTTTATCCTGAGAGAAAGTTCGTTGGTTTTTTTGTGGGAGTGATGTCGAATCCTGGGACTCGAAGGAACGGGTCAAGCATCAAAATCCGACTGACAGtATTATGTGCCAAGAATCTAGCAAAGAAAGACTTCTTCCGGTTGCCTGATCCTTTTGCCAAAGTGGTGGTGGACGGCTCGGGTCAATGCCACTCTACAGACACGGTCAAAAGCACACTGGACCCCAAGTGGAATCAGCATTACGACCTGTATATTGGGAAGACCGATTCCATCACCATTAGCGTATGGAACCATAAGAAGATCCATAAGAAGCAGGGTGCGGGATTCTTAGGCTGCGTGCGGCTCTTGTCAAACGCTATCAGCAGACTAAAAGACACAGGCTACCAGCGTTTAGACTTATGCAAGTTAAACCCATCTGACAGTGATGCTGTCCGTGGACAAATCGTTGTGAGTTTGCAGACCAGAGACAGAATTGGCAGTGGAGGGCCTGTGGTGGACTGTCGAGGACTGGTAGAGAATGAAGGGCCAGTCTTTGAAGACTCGGGACCCGGACGGCCTCTCAGCTGCTTCATGGAGGAGCCCATGCCATACACCGATCCCACAGGAGCCGCTGGAGGGGGCAACTGCCGTGCACTTGAGTCACCCAATCAGGAACAACGGCTCCAAGCACAACGCATCAGAAACCAGGATTCCCGAGGGCACACGCACACCCCCCAGAATCGACCGCACGGACACCAATCCCCCGACCTCCCTGAGGGCTATGAGCAAAGGACCACCGTGCAGGGCCAAGTCTATTTTCTGCACACACAGACTGGCGTGAGCACCTGGCACGATCCCAGAATACCCCGGGATTTGAACAGCGTGAGTTGTGAGGAGCTGGGCCCACTGCCGCCCGGCTGGGAGATCAGGAGCACTGTGTCAGGACGAATTTATTTCGTCGACCACAATAATAGAACCACGCAATTCACCGACCCCAGGTTACACCACATCATGAGCCAACACTCTCAGGTGAAGGAGTCGAGCCAGGCTCTGCCCGTGCAGATGGAGGTTGGCATGGAGGAGGGTGATGGAGAGTTGCCGGTGCGCTACGAAAGAGATCTTGTCCAGAAACTCAAAGTTCTCCGGCATGAGCTCTCGCTGCAGCAGCCTCAGGCCGGCCACTGCCGCATAGAAGTGTCCCGCGAGGAGATCTTTGAGGAGTCTTATAGGCAGATCATGAAGATGAGACCCAAAGACCTGAAGAAGCGGCTGATGGTGAAGTTCAGAGGCGAGGAGGGGCTGGATTACGGAGGAGTTGCTAGGGAGTGGTTATATCTGCTCTGCCATGAGATGCTGAATCCATACTATGGCTTGTTTCAGTACTCGACCGATAACATCTACACACTACAGATCAACCCAGACTCCTCCATTAACCCTGATCACTTGTCTTACTTCCACTTTGTTGGGCGGATTATGGGTCTGGCTGTTTTCCACGGGCACTACATTAACGGGGGCTTCACCTTGCCCTTCTACAAGCAGCTCCTGGGGAAACCCATTCAGCTTTGTGACCTTGAGACCGTGGACCCAGAGCTGCACAAGAGTCTCGTCTGGATCCTAGAAAATGACATCACATCTGTTTTGGACCACACCTTCTGCGTAGAACATAATGCTTTCGGCAAGTTCCTCCAACATGAGCTCAAACCAAATGGCAAGAACATCCCAGTCACAGAGGAGAACAAGAAAGAATACGTGAGGCTGTACGTCAACTGGAGGTTCATGCGAGGCATCGAGGCACAGTTTCTTGCCCTGCAAAAGGGCTTCAACGAACTCATACCGCAGCATCTGCTCAAGCCTTTCGACAACAAGGAACTTGAGcTGATCATCGGTGGTTTGGGGAAGATCGATCTGAACGACTGGAAGGCCAACACGCGGCTGAAGCACTGTGTGGCTGACAGCAACATCGTGAAGTGGTTTTGGCAGGCGGTGGAGTCGTTTGACGAGGAGAGGAGAGGCAGACTCTTACAGTTCGTGACAGGCTCCACACGCGTCCCTCTACAAGGCTTTAAAGCACTGCAAGGTTCTACAGGTTCTGCAGGACCAAGACTCTTCACTATTCATTTAATTGATGCCAACACAGACAACCTGCCCAAAGCCCACACATGTTTCAACCGTATCGACATCCCGCCTTACGAGTCGTACGAGAAGCTGTATGAAAAGCTCCTGACAGCAGTGGAGGAGACATGTGGTTTCGCAGTGGAGTGAGCAAGCGCCCTGTCCAGCCAGCCAGCAATGGCAGCAAAAGCCACCAAACAGCCCCTGCCACCCTCTCACACCCCTCCCCTTCTGCAGGACAGACGGACTGGTGTCTCCCGACAGACTTTAGCATCACACTGCAGTGGAGGGCAGCGAACACCCTAGGTGTTTCAACTCATTGACTAATGGTTTTGGCATTACCACAACGAGTTCCAGAGGAAATGTAGTTTCTCAACAATGCAGTTGGTATCGTCTTTGTCACTGAAGCGGCGGGTTGATGCGCGAGTGTGTTTGTGCTGCAGTACATAGAGCCTCGCTGAGCCCGTGATCTACTTGAAGTAGAGCTCACGTTTTTTTTAGTCTAGGGGGAggattttaacacacacacacacactcagagcctGTGACCGTTAAACCAGTTTACCTACAGAAAAATGTGTCTCAAAGGACAAGGCTTGCGTTTGTCATGCTCGATGTATGTAAACGTCTCcaattgttttcctttttttttttttccccttgcgTCCCGTTTAGTGCTATAGGATGACATTTCAGTGGTATCCATTTCCTGTGCTCTTCAGTTCTCATTGTAGAAATTTTAACTCGATTGCTTGAAATGTATTGTTGAaatgattattactattatttttgtgTCTAAGATCAAGAACATGCTTGACGGCGAGTCTTAGTCCTGTTGTGGGAACTGAATGTACCAGCGCCCATGTGTTCATGTTGAAGCACAACCATCGTGTGCGGTCGAAACACCAAATGTTCTCACGGAGTTACAGTATTTTTGTCGCAGAACTTCttttaacccttttttttttttatccaatgtAAGCAAAACATTTGAATTTGAAGCATGTCACCTTCTCCAATGGCGTTCGGCTTCTTAAACCGAACTCGTAAGAAGATCAGATGCTTTAAAGAAGCTCTTCTTGTCCTTAATTTTGATGGACCCCGTTaatcttttccaaatgattattATATGGTAAGCATTAACCGTTTTAACCTACCGTAAACTTGACTGTTATTTGCTTGTTTCGTTGATCAAAACCACTGCTTCGTGGAACATTCGGCACTTCCGCTGGCACATGTACGATCGGAGTGGACGAATGCTTCGCTCCTAGACTCTGACGGAGAGGCTTTTCTGGTTTTGGTGTGCTGAAAGAGCAGGGAAGTGTTCAAGATTTCATTATGTAGTGCTTGACGTGCATGGCACCAGATTATTCTTTGTAAATGTAAAGGATGAGCCAACCTCATGGTGTTTCTTCAACCACTTTTGTCCTTTTTCTTTTCCTcctaattttttttaaccaattatttATTACCATGTAATGTCTTTTTAAGTATTGCTGCTATTACCATTATTCCATAGTTTTCAGAGAAAGCTGAGTTCTTGTGAAAGCTGTACACTAAtctcttttattttatgtatgaaTCAAAGTATTTAAACCTGCTGCTGATTCTTCAGGAGGTTAAGAGGATCGGTTCGCCTGATCTTTTGACCTGGATGGAGTTGGCGAGTGATGTAGGCCAGGCCCCGGTGGTCATGTTCATATTTGTGATATATGCAATAAAATCCATCACCTTTTTATTCTTGGTTCTGTCTTACAATGTCTTCTTCCTCACTTCAGATCGGTTGGGATGTGTCTTTGACGAGTGTGCAAAAATGAAGTTTTCCAATTTTCCAAAAGACCGTGAATGCCTACAGTGGTGAACCGTTTTTAAAACTTGCATACAACACAAGAGAGGTGATGTTTAATGTTGTGTAATTGTGGGAATGGCTAGTGAGCTTGAAGATGAGTCTGGACTTTGCCTGAAGTTAcagttgttttcatttttctctaagaaaaaactttttttttttttttttggagtaatGTGACCAGTATCATCACATTGTACAATTATTAGGTCCTGAGTGTCATTGTTTATTCGATGCAAGAGTAATGTAACTTACTATGTACTAAACATTTCTGAAACAAATTCAGTGTAAATAAGATTATATTAAAGAAACTAAATTGCAAA

Function

symbol description
smurf1 Predicted to enable ubiquitin protein ligase activity. Predicted to be involved in several processes, including negative regulation of BMP signaling pathway; protein polyubiquitination; and ubiquitin-dependent protein catabolic process. Predicted to act upstream of or within ubiquitin-dependent protein catabolic process. Predicted to be active in cytoplasm. Is expressed in alar plate midbrain region; axis; midbrain; neural plate; and notochord. Orthologous to human SMURF1 (SMAD specific E3 ubiquitin protein ligase 1).

GO:

id name namespace
GO:0045732 positive regulation of protein catabolic process biological_process
GO:0030514 negative regulation of BMP signaling pathway biological_process
GO:0016567 protein ubiquitination biological_process
GO:0043161 proteasome-mediated ubiquitin-dependent protein catabolic process biological_process
GO:0006511 ubiquitin-dependent protein catabolic process biological_process
GO:0030579 ubiquitin-dependent SMAD protein catabolic process biological_process
GO:0000209 protein polyubiquitination biological_process
GO:0005737 cytoplasm cellular_component
GO:0016740 transferase activity molecular_function
GO:0004842 ubiquitin-protein transferase activity molecular_function
GO:0061630 ubiquitin protein ligase activity molecular_function

KEGG: NA

ZFIN:

id description
ZDB-GENE-040426-2744 Predicted to enable ubiquitin protein ligase activity. Predicted to be involved in several processes, including negative regulation of BMP signaling pathway; protein polyubiquitination; and ubiquitin-dependent protein catabolic process. Predicted to act upstream of or within ubiquitin-dependent protein catabolic process. Predicted to be active in cytoplasm. Is expressed in alar plate midbrain region; axis; midbrain; neural plate; and notochord. Orthologous to human SMURF1 (SMAD specific E3 ubiquitin protein ligase 1).

Ensembl:

ensembl_id ENSDARG00000016086

RNA

RNA id representative length rna type GC content exon number start site end site
TCONS_00051947 True 4409 mRNA 0.47 18 40690212 40768548

Neighbor

gene id symbol gene type direction distance location
XLOC_026669 uts2r5 coding downstream 9211 40679931 ~ 40681001 (-)
XLOC_026668 rnf216 coding downstream 25299 40600770 ~ 40664913 (-)
XLOC_026667 actb2 coding downstream 160408 40526107 ~ 40529804 (-)
XLOC_026666 NA coding downstream 284826 40396063 ~ 40405386 (-)
XLOC_026665 atp5mf coding downstream 388745 40296785 ~ 40301467 (-)
XLOC_026671 NA coding upstream 5870 40774418 ~ 40777723 (-)
XLOC_026672 wipi2 coding upstream 53109 40821657 ~ 40837218 (-)
XLOC_026673 ap5z1 coding upstream 108005 40876553 ~ 40896927 (-)
XLOC_026674 foxk1 coding upstream 133195 40901743 ~ 40933415 (-)
XLOC_026675 cyp3c4 coding upstream 167546 40936094 ~ 40945724 (-)
XLOC_026659 NA non-coding downstream 508558 40180136 ~ 40181654 (-)
XLOC_026657 BX649547.1 non-coding downstream 601411 40088685 ~ 40088801 (-)
XLOC_026654 BX649356.3 non-coding downstream 732738 39957358 ~ 39957474 (-)
XLOC_026653 BX649356.2 non-coding downstream 738685 39945865 ~ 39951527 (-)
XLOC_026680 CR769786.1 non-coding upstream 543474 41312022 ~ 41312143 (-)
XLOC_026681 BX537310.2 non-coding upstream 627575 41396123 ~ 41512210 (-)
XLOC_026687 NA non-coding upstream 1414805 42183353 ~ 42205112 (-)
XLOC_026688 BX005183.3 non-coding upstream 1444162 42212710 ~ 42216013 (-)

Expression


Co-expression Network

Homologous

species gene id symbol gene type chromosome NCBI id location
grasscarp (Ctenopharyngodon idella) CI01000046_03680288_03699097 SMURF1 coding CI01000046 null 3680288 ~ 3699097 (+)
bowfin (Amia calva) AMCG00018531 smurf1,LOC107720062,LOC107591759,LOC107703417,LOC107581717 coding CM030135.1 CM030135.1 13783853 ~ 13832385 (-)