XLOC_026676 (cyp3c3)


Basic Information

Item Value
gene id XLOC_026676
gene name cyp3c3
gene type coding
species zebrafish (Danio rerio)
category of species model fish

Chromosome Information

Item Value
chromosome id NC_007114.7
NCBI id CM002887.2
chromosome length 62628489
location 40947961 ~ 40955780 (-)
genome version GRCz11_2017_zebrafish_Genome

Sequence

>TCONS_00051954
CAGTTCTGCGTGTAAAACATCTTTTCAGTAAGGATTAATGGCAAATATTATGAACCATATTAATAAGTCATCAGTTCATTACTGAATACCCGTCACCGGTGTGTTTAAGGCCACTACACTGAAGAATACAGTGATTTACAATGATTGATCTCTCATCTCTGTCTGTGACATGGACCCTGGTGTTTCTGGTTATAACCCTCCTGTATATGTATGGTGTTTGGCCACATGGATTTTTCAAAAAACTGGGAATTCCAGGACCAAGACCCTGGCCTTTTTTTGGCACATTTCTCTCGTACACTAAAggCTTTTTTAATTTCGATATGGAGTGTGCCAAGAAGTATGGAAAAGTATGGGGGATCTATGATGGAAGACTGCCGATACTAATGGTCACAGACTTGGAAATGATCAAAACGATTATGGTGAAAGAATGTTATTCTACCTTCACTAACCGAAGGGAAGTAAATGTGGATCTTGCTGGCCCCCTTGCTGATGGAATATCTGCAGTTAAAGATGAGAGGTGGAAGCGAATCCGTGGTACACTCTCTCCATATTTCACTAGTGGCCGGCTGAAGGAGATATTTCCTATAGCCATGACACATGCTGATCggtttattaaaaatatgcaaaagaGAGACCACGAGCAGCCGGTTAAAATAAAAGAagtTGTCGCTCCATACAGTTTAGATGTGGTCACCAGCTCATCTTTTAGCGTTGACATCGACTCTATTAATAACCCCGATGATCCCTTTGTTACCAACATAAAGAACTTTTTAAAGTTCAGTCTGTTCagtcctttaattctttttttgaCTTTATTCCCCTCCATTGCAAATCTTTTGGGGAAAATGGGAATAAGTGTGTTTTCAAGGTCAATTATGAATTTCTTCTACACGGCCCTGAGAAAGATAAAGGACGAGCACAAGGATTCAAATggtCGAGTAGACTTTCTCAGGCTCATGATCCAGAATCAAATACCTGATGATCAAGCGAAAGACACCACAAGTGAACAACCAGTAAAAGGATTAACAGACCATGAGATTCTCTCCCAATCCTTCATTTTTATCCTGGGCGGTTATGAGACAACAAGCACGACTCTCTCTTTCCTCCTCCATAATCTTGCTACTAACCCCGACTGCCTGGAAAAGCTGGTGGAGGAGATTGACAAAAACTTCCCTCTTGATACTCCCATCTCATACGATGCATTGATGAAAATGGATTACTTGGAAATGTCTATAAATGAGTCAATGCGTCTCCTTCCCACTGCCCCTCGCTTGGAAAGGGTCTGTAAGAAGACTGTAGAGCTAAATGGCATCACCATACCAAAGGACACACTGGTTGCAATTCCTACATATGTTTTAAATCGTGACCCGCAGCTCTGGGATTCTCCTCAGGAGTTCAGGCCTGAGAGGTTCAGTCCAGAGAATAAGTCTGAGTTTCTCCAGTACGCTTTCATGCCTTTTGGACTCGGGCCTCGAAACTGCATTGGGATGAGGTTTGCTCTAATGATCGTGAAGCTTCTTGTTGTGAAGCTGCTACAGAACTTCAGTTTGGAAACATGTAAAGAGACGCAGATCCCTCTAGAGCTGACTCCTGTTTTCCAGCCAAAGGTTCCCATCACACTGAAGTTAACACCAAGGAAAAGGAATAATTAAAATACAGAACATGTTTATGGAATTGTGCAGATTAGATAGAATTTTAAACAATTACATGCAGCTTTATTTTAAGTATCTATATTTTACAGCATGCTATCAGCCTTTTTTATATTCAACTTTTACAGCAGACTTTTTCAATGTATGCTGCTGATGATtcctgattcattcattttgagtagtttaaaatgtaagtaaaacaCTACATGTCAAAATGACAATTCAGATGTAATCATGTCTAATTAAATACCAGTATAAAGCAAGCGAGGCATTTTACACagtcagttttgttttttacccagtgactttttgttttgattgagcaaacactgaggttttaagctcAAGGAGGTGATTTTGATCAGGTTTTGTTTCTATGATAACTTACTATTTCTTTTGAGCTGTTGGTAAACCTACATTATTAAAACAAGTTGACTGATTTACATTTATATGATAATATTTGCTTTTAGTCTTCTCAAACTTTCACTGTATCAGCAGTTTATTTTGGCCTTGTGGATGTGTTTAAATTCATTATATTTCTGATAATAAAAGCTTAATCTTCAGCAAAGAATTGGA

Function

symbol description
cyp3c3 Predicted to enable steroid hydroxylase activity. Predicted to be located in membrane. Predicted to be integral component of membrane. Is expressed in several structures, including adaxial cell; heart; liver; nervous system; and pleuroperitoneal region. Human ortholog(s) of this gene implicated in B-lymphoblastic leukemia/lymphoma; acute lymphoblastic leukemia; chronic myeloid leukemia; essential hypertension; and familial Mediterranean fever. Orthologous to several human genes including CYP3A4 (cytochrome P450 family 3 subfamily A member 4); CYP3A43 (cytochrome P450 family 3 subfamily A member 43); and CYP3A5 (cytochrome P450 family 3 subfamily A member 5).

GO:

id name namespace
GO:0055114 oxidation-reduction process biological_process
GO:0016020 membrane cellular_component
GO:0016021 integral component of membrane cellular_component
GO:0008395 steroid hydroxylase activity molecular_function
GO:0016705 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen molecular_function
GO:0004497 monooxygenase activity molecular_function
GO:0005506 iron ion binding molecular_function
GO:0046872 metal ion binding molecular_function
GO:0016491 oxidoreductase activity molecular_function
GO:0020037 heme binding molecular_function

KEGG: NA

ZFIN:

id description
ZDB-GENE-041114-102 Predicted to enable steroid hydroxylase activity. Predicted to be located in membrane. Predicted to be integral component of membrane. Is expressed in several structures, including adaxial cell; heart; liver; nervous system; and pleuroperitoneal region. Human ortholog(s) of this gene implicated in B-lymphoblastic leukemia/lymphoma; acute lymphoblastic leukemia; chronic myeloid leukemia; essential hypertension; and familial Mediterranean fever. Orthologous to several human genes including CYP3A4 (cytochrome P450 family 3 subfamily A member 4); CYP3A43 (cytochrome P450 family 3 subfamily A member 43); and CYP3A5 (cytochrome P450 family 3 subfamily A member 5).

Ensembl:

ensembl_id ENSDARG00000037873

RNA

RNA id representative length rna type GC content exon number start site end site
TCONS_00051954 True 2225 mRNA 0.39 14 40947961 40955780

Neighbor

gene id symbol gene type direction distance location
XLOC_026675 cyp3c4 coding downstream 2237 40936094 ~ 40945724 (-)
XLOC_026674 foxk1 coding downstream 14546 40901743 ~ 40933415 (-)
XLOC_026673 ap5z1 coding downstream 51034 40876553 ~ 40896927 (-)
XLOC_026672 wipi2 coding downstream 110743 40821657 ~ 40837218 (-)
XLOC_026671 NA coding downstream 170238 40774418 ~ 40777723 (-)
XLOC_026677 cyp3c3 coding upstream 3090 40958870 ~ 40965596 (-)
XLOC_026678 cyp3c1 coding upstream 13462 40969242 ~ 40976582 (-)
XLOC_026679 sdk1a coding upstream 23217 40978997 ~ 41292569 (-)
XLOC_026680 CR769786.1 coding upstream 356242 41312022 ~ 41312143 (-)
XLOC_026681 BX537310.2 coding upstream 440343 41396123 ~ 41512210 (-)
XLOC_026666 NA non-coding downstream 542575 40396063 ~ 40405386 (-)
XLOC_026659 NA non-coding downstream 766307 40180136 ~ 40181654 (-)
XLOC_026657 BX649547.1 non-coding downstream 859160 40088685 ~ 40088801 (-)
XLOC_026654 BX649356.3 non-coding downstream 990487 39957358 ~ 39957474 (-)
XLOC_026687 NA non-coding upstream 1227573 42183353 ~ 42205112 (-)
XLOC_026688 BX005183.3 non-coding upstream 1256930 42212710 ~ 42216013 (-)
XLOC_026689 NA non-coding upstream 1416004 42371784 ~ 42373599 (-)

Expression


Co-expression Network

Homologous

species gene id symbol gene type chromosome NCBI id location
grasscarp (Ctenopharyngodon idella) CI01032482_00000224_00008081 NA coding CI01032482 null 224 ~ 8081 (-)