XLOC_026677 (cyp3c3)


Basic Information

Item Value
gene id XLOC_026677
gene name cyp3c3
gene type coding
species zebrafish (Danio rerio)
category of species model fish

Chromosome Information

Item Value
chromosome id NC_007114.7
NCBI id CM002887.2
chromosome length 62628489
location 40958870 ~ 40965596 (-)
genome version GRCz11_2017_zebrafish_Genome

Sequence

>TCONS_00051955
TGTGCATGAGGCCACTAGTGTACTGAATAATACAGTGATTTACAATGATTGATCTTTCATCTCTGTCTGTGACCTGGATCCTGGTGGTTCTGGTTTTAACCCTCCTGTATATGTATGGTGTTTGGCCACATGGATTTTTCAAAAAACTAGGAATTCCAGGACCAAGACCCTGGCCTTTTTTTGGCACATTTCTTTCGTACACTAaaggCTTTTTTAATTTCGATATGGAGTGTGCCAAGAAGTATGGAAAAGTATGGGGGATCTATGATGGAAGGTTGCCGATACTAATGGTCACTGACCTTGAAATGATCAAAACGATTATGGTGAAAGAATGTTATTCTACCTTCACTAACCGAAGGGAAATAAATGTGGATCTTGCTGGCCCCCTTGCTGATGGAATAACTGCAGTTAAAGATGAGAGGTGGAAGCGAATCCGTGGTACACTCTCTCCATATTTCACTAGTGGCCGGCTGAAGGAGATATTTCCCATAGCCATGACACATGCAGATCggtttattaaaaatatgcaaaaggGGGACCACGAACAGCCAGTTAAAATCAAAGAAGTTATGGCTTCATACAGTTTAGATGTGGTCACCAGCTCAGCTTTTAGCGTTGATATCGACTCTATTAATAACCCTGATGATCCCTTTGTTACCAACATAAAGaactttttaaagtttaatcTGTTTGGTCTTTTCGTTCTTCTTTTGACTGTATTCCCCTCTATTGCAAATCTTTTGGGGAAGATGGGATTAAGCATGTTTTCAAAGCCGACTGTGGATTTTTTCTACAAGGCCCTGAGAAAGATAAAGGAGGAGCACAAGGATTCAAATGGTCGGGTAGACTTTTTCAGACTCATGATACAGAATGAAATACCTGATGATCAAGTGAAGGACACTACAAGTGAACAACCAGAAAAAGGATTAACAGACCATGAGATTCTCTCCCAATCCTTTATTTTTATCATGGGTGGTTATGAGACTACAAGCACGACTCTCACTTTCCTTCTCTATAATCTTGCTATTAATCCGGACTGCCTGGAAAAGCTGGTTGAGAAGATCGACAAAAACTTCCCTCTTGATACTCCCATCTCATACGATGCATTGATGAAAATAGATTACTTGGAAATGTCTATAAATGAGTCAATGCGTCTCCTACCCACTGCCCCACGCTTGGAAAGGGTCTGTAAGAAGACTGTAGAGATGAATGGCATCACCATACCAAAGGACACAATGATTACAATTCCTACATATGTTTTAAATCAAGACCCGCAGCTCTGGGATTCCCCTCATGAGTTCAGGCCTGAAAGGTTCAGTCCAGAGAATAAGTCTGAGTTTCTCCAGTACGCTTTTATGCCTTTTGGACTCGGGCCTCGAAACTGCATTGGAATGAGATATGCTCTAATGATCGTAAAGCTTCTTGTTGTGAAGCTGCTACAGAACTTCAGTGTAGAAACATGTAAAGAAACGCAGatccCTCTAGAGCTGAATCCTGTTTTTCAGCCAAAGGTTCCCATCACACTGAAGTTAACACCCAGGAAAAGGAATAATTAAAATACAGAACATGTTTATGTGATT
>TCONS_00051956
TCTTTGTATGGTGTTTGGCCACATGGATTTTTCAAAAAACTAGGAATTCCAGGACCAAGACCCTGGCCTTTTTTTGGCACATTTCTTTCGTACACTAaaggCTTTTTTAATTTCGATATGGAGTGTGCCAAGAAGTATGGAAAAGTATGGGGGATCTATGATGGAAGGTTGCCGATACTAATGGTCACTGACCTTGAAATGATCAAAACGATTATGGTGAAAGAATGTTATTCTACCTTCACTAACCGAAGGGAAATAAATGTGGATCTTGCTGGCCCCCTTGCTGATGGAATAACTGCAGTTAAAGATGAGAGGTGGAAGCGAATCCGTGGTACACTCTCTCCATATTTCACTAGTGGCCGGCTGAAGGAGATATTTCCCATAGCCATGACACATGCAGATCggtttattaaaaatatgcaaaaggGGGACCACGAACAGCCAGTTAAAATCAAAGAAGTTATGGCTTCATACAGTTTAGATGTGGTCACCAGCTCAGCTTTTAGCGTTGATATCGACTCTATTAATAACCCTGATGATCCCTTTGTTACCAACATAAAGaactttttaaagtttaatcTGTTTGGTCTTTTCGTTCTTCTTTTGACTGTATTCCCCTCTATTGCAAATCTTTTGGGGAAGATGGGATTAAGCATGTTTTCAAAGCCGACTGTGGATTTTTTCTACAAGGCCCTGAGAAAGATAAAGGAGGAGCACAAGGATTCAAATGGTCGGGTAGACTTTTTCAGACTCATGATACAGAATGAAATACCTGATGATCAAGTGAAGGACACTACAAGTGAACAACCAGAAAAAGGATTAACAGACCATGAGATTCTCTCCCAATCCTTTATTTTTATCATGGGTGGTTATGAGACTACAAGCACGACTCTCACTTTCCTTCTCTATAATCTTGCTATTAATCCGGACTGCCTGGAAAAGCTGGTTGAGAAGATCGACAAAAACTTCCCTCTTGATACTCCCATCTCATACGATGCATTGATGAAAATAGATTACTTGGAAATGTCTATAAATGAGTCAATGCGTCTCCTACCCACTGCCCCACGCTTGGAAAGGGTCTGTAAGAAGACTGTAGAGATGAATGGCATCACCATACCAAAGGACACAATGATTACAATTCCTACATATGTTTTAAATCAAGACCCGCAGCTCTGGGATTCCCCTCATGAGTTCAGGCCTGAAAGGTTCAGTCCAGAGAATAAGTCTGAGTTTCTCCAGTACGCTTTTATGCCTTTTGGACTCGGGCCTCGAAACTGCATTGGAATGAGATATGCTCTAATGATCGTAAAGCTTCTTGTTGTGAAGCTGCTACAGAACTTCAGTGTAGAAACATGTAAAGAAACGCAGatccCTCTAGAGCTGAATCCTGTTTTTCAGCCAAAGGTTCCCATCACACTGAAGTTAACACCCAGGAAAAGGAATAATTAA
>TCONS_00051957
CTGTATTCCCCTCTATTGCAAATCTTTTGGGGAAGATGGGATTAAGCATGTTTTCAAAGCCGACTGTGGATTTTTTCTACAAGGCCCTGAGAAAGATAAAGGAGGAGCACAAGGATTCAAATGTATGTTTGTCACTTTTTCACTCTTCAGATGCAGTTTTAGATTTGGCAGAGATGCACCCAGTGGAAACCTACATGAACACGGGATATAAgtaatattgtgttttttaattataGGGTCGGGTAGACTTTTTCAGACTCATGATACAGAATGAAATACCTGATGATCAAGTGAAGGACACTACAAGTGAACAACCAGAAAAAGGATTAACAGACCATGAGATTCTCTCCCAATCCTTTATTTTTATCATGGGTGGTTATGAGACTACAAGCACGACTCTCACTTTCCTTCTCTATAATCTTGCTATTAATCCGGACTGCCTGGAAAAGCTGGTTGAGAAGATCGACAAAAACTTCCCTCTTGATACTCCCATCTCATACGATGCATTGATGAAAATAGATTACTTGGAAATG

Function

symbol description
cyp3c3 Predicted to enable steroid hydroxylase activity. Predicted to be located in membrane. Predicted to be integral component of membrane. Is expressed in several structures, including adaxial cell; heart; liver; nervous system; and pleuroperitoneal region. Human ortholog(s) of this gene implicated in B-lymphoblastic leukemia/lymphoma; acute lymphoblastic leukemia; chronic myeloid leukemia; essential hypertension; and familial Mediterranean fever. Orthologous to several human genes including CYP3A4 (cytochrome P450 family 3 subfamily A member 4); CYP3A43 (cytochrome P450 family 3 subfamily A member 43); and CYP3A5 (cytochrome P450 family 3 subfamily A member 5).

GO:

id name namespace
GO:0055114 oxidation-reduction process biological_process
GO:0016020 membrane cellular_component
GO:0016021 integral component of membrane cellular_component
GO:0008395 steroid hydroxylase activity molecular_function
GO:0016705 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen molecular_function
GO:0004497 monooxygenase activity molecular_function
GO:0005506 iron ion binding molecular_function
GO:0046872 metal ion binding molecular_function
GO:0016491 oxidoreductase activity molecular_function
GO:0020037 heme binding molecular_function

KEGG: NA

ZFIN:

id description
ZDB-GENE-041114-102 Predicted to enable steroid hydroxylase activity. Predicted to be located in membrane. Predicted to be integral component of membrane. Is expressed in several structures, including adaxial cell; heart; liver; nervous system; and pleuroperitoneal region. Human ortholog(s) of this gene implicated in B-lymphoblastic leukemia/lymphoma; acute lymphoblastic leukemia; chronic myeloid leukemia; essential hypertension; and familial Mediterranean fever. Orthologous to several human genes including CYP3A4 (cytochrome P450 family 3 subfamily A member 4); CYP3A43 (cytochrome P450 family 3 subfamily A member 43); and CYP3A5 (cytochrome P450 family 3 subfamily A member 5).

Ensembl:

ensembl_id ENSDARG00000037874

RNA

RNA id representative length rna type GC content exon number start site end site
TCONS_00051955 False 1580 mRNA 0.41 13 40958870 40965596
TCONS_00051956 False 1449 mRNA 0.41 13 40958894 40965328
TCONS_00051957 True 533 lncRNA 0.39 3 40959578 40962832

Neighbor

gene id symbol gene type direction distance location
XLOC_026676 cyp3c3 coding downstream 3090 40947961 ~ 40955780 (-)
XLOC_026675 cyp3c4 coding downstream 13146 40936094 ~ 40945724 (-)
XLOC_026674 foxk1 coding downstream 25455 40901743 ~ 40933415 (-)
XLOC_026673 ap5z1 coding downstream 61943 40876553 ~ 40896927 (-)
XLOC_026672 wipi2 coding downstream 121652 40821657 ~ 40837218 (-)
XLOC_026678 cyp3c1 coding upstream 3646 40969242 ~ 40976582 (-)
XLOC_026679 sdk1a coding upstream 13401 40978997 ~ 41292569 (-)
XLOC_026680 CR769786.1 coding upstream 346426 41312022 ~ 41312143 (-)
XLOC_026681 BX537310.2 coding upstream 430527 41396123 ~ 41512210 (-)
XLOC_026682 si:ch211-222n22.1 coding upstream 565683 41531279 ~ 41535761 (-)
XLOC_026671 NA non-coding downstream 181147 40774418 ~ 40777723 (-)
XLOC_026666 NA non-coding downstream 553484 40396063 ~ 40405386 (-)
XLOC_026659 NA non-coding downstream 777216 40180136 ~ 40181654 (-)
XLOC_026657 BX649547.1 non-coding downstream 870069 40088685 ~ 40088801 (-)
XLOC_026654 BX649356.3 non-coding downstream 1001396 39957358 ~ 39957474 (-)
XLOC_026687 NA non-coding upstream 1217757 42183353 ~ 42205112 (-)
XLOC_026688 BX005183.3 non-coding upstream 1247114 42212710 ~ 42216013 (-)
XLOC_026689 NA non-coding upstream 1406188 42371784 ~ 42373599 (-)

Expression


Co-expression Network