Item | Value |
---|---|
gene id | XLOC_026698 |
gene name | axin1 |
gene type | coding |
species | zebrafish (Danio rerio) |
category of species | model fish |
Item | Value |
---|---|
chromosome id | NC_007114.7 |
NCBI id | CM002887.2 |
chromosome length | 62628489 |
location | 43578975 ~ 43686469 (-) |
genome version | GRCz11_2017_zebrafish_Genome |
symbol | description |
---|---|
axin1 | Predicted to enable protein homodimerization activity. Involved in several processes, including negative regulation of Wnt signaling pathway involved in dorsal/ventral axis specification; positive regulation of MAPK cascade; and regionalization. Acts upstream of or within several processes, including embryonic morphogenesis; fin regeneration; and regionalization. Part of beta-catenin destruction complex. Is expressed in forebrain; habenula; head; and midbrain. Human ortholog(s) of this gene implicated in hepatocellular carcinoma. Orthologous to human AXIN1 (axin 1). |
id | name | namespace |
---|---|---|
GO:0090244 | Wnt signaling pathway involved in somitogenesis | biological_process |
GO:0021797 | forebrain anterior/posterior pattern specification | biological_process |
GO:0001743 | optic placode formation | biological_process |
GO:0001756 | somitogenesis | biological_process |
GO:0055001 | muscle cell development | biological_process |
GO:0007257 | activation of JUN kinase activity | biological_process |
GO:0030178 | negative regulation of Wnt signaling pathway | biological_process |
GO:0046330 | positive regulation of JNK cascade | biological_process |
GO:0007275 | multicellular organism development | biological_process |
GO:0021877 | forebrain neuron fate commitment | biological_process |
GO:0090090 | negative regulation of canonical Wnt signaling pathway | biological_process |
GO:0009950 | dorsal/ventral axis specification | biological_process |
GO:0009953 | dorsal/ventral pattern formation | biological_process |
GO:0031101 | fin regeneration | biological_process |
GO:2000054 | negative regulation of Wnt signaling pathway involved in dorsal/ventral axis specification | biological_process |
GO:0007368 | determination of left/right symmetry | biological_process |
GO:0048048 | embryonic eye morphogenesis | biological_process |
GO:0001654 | eye development | biological_process |
GO:0021999 | neural plate anterior/posterior regionalization | biological_process |
GO:0030900 | forebrain development | biological_process |
GO:0030910 | olfactory placode formation | biological_process |
GO:0016055 | Wnt signaling pathway | biological_process |
GO:0005886 | plasma membrane | cellular_component |
GO:0005634 | nucleus | cellular_component |
GO:0030877 | beta-catenin destruction complex | cellular_component |
GO:0016020 | membrane | cellular_component |
GO:0005737 | cytoplasm | cellular_component |
GO:0005515 | protein binding | molecular_function |
GO:0042803 | protein homodimerization activity | molecular_function |
GO:0008013 | beta-catenin binding | molecular_function |
id | description |
---|---|
ko04310 | Wnt signaling pathway |
ko04390 | Hippo signaling pathway |
ko04550 | Signaling pathways regulating pluripotency of stem cells |
ko05200 | Pathways in cancer |
ko05210 | Colorectal cancer |
ko05225 | Hepatocellular carcinoma |
ko05226 | Gastric cancer |
ko05217 | Basal cell carcinoma |
ko05213 | Endometrial cancer |
ko05224 | Breast cancer |
ko05165 | Human papillomavirus infection |
ko05010 | Alzheimer disease |
ko05022 | Pathways of neurodegeneration - multiple diseases |
ko04934 | Cushing syndrome |
ko01009 | Protein phosphatases and associated proteins |
id | description |
---|---|
ZDB-GENE-000403-1 | Predicted to enable protein homodimerization activity. Involved in several processes, including negative regulation of Wnt signaling pathway involved in dorsal/ventral axis specification; positive regulation of MAPK cascade; and regionalization. Acts upstream of or within several processes, including embryonic morphogenesis; fin regeneration; and regionalization. Part of beta-catenin destruction complex. Is expressed in forebrain; habenula; head; and midbrain. Human ortholog(s) of this gene implicated in hepatocellular carcinoma. Orthologous to human AXIN1 (axin 1). |
ensembl_id | ENSDARG00000102964 |
RNA id | representative | length | rna type | GC content | exon number | start site | end site |
---|---|---|---|---|---|---|---|
TCONS_00051987 | False | 5691 | mRNA | 0.47 | 10 | 43578975 | 43662495 |
TCONS_00053099 | False | 2009 | lncRNA | 0.42 | 2 | 43579490 | 43582355 |
TCONS_00051988 | False | 4734 | mRNA | 0.50 | 10 | 43579490 | 43650189 |
TCONS_00051989 | False | 3049 | mRNA | 0.54 | 9 | 43580962 | 43646733 |
TCONS_00052486 | True | 513 | lncRNA | 0.41 | 2 | 43661692 | 43686469 |
gene id | symbol | gene type | direction | distance | location |
---|---|---|---|---|---|
XLOC_026697 | uncx | coding | downstream | 222893 | 43352556 ~ 43356082 (-) |
XLOC_026695 | NA | coding | downstream | 389890 | 43187194 ~ 43189085 (-) |
XLOC_026694 | NA | coding | downstream | 552240 | 43024821 ~ 43026735 (-) |
XLOC_026693 | mafk | coding | downstream | 597236 | 42964045 ~ 42981739 (-) |
XLOC_026692 | BX908797.1 | coding | downstream | 610431 | 42918143 ~ 42968544 (-) |
XLOC_026699 | zgc:92162 | coding | upstream | 70712 | 43757181 ~ 43770876 (-) |
XLOC_026700 | rmi2 | coding | upstream | 142076 | 43828545 ~ 43835055 (-) |
XLOC_026701 | mslna | coding | upstream | 149089 | 43835558 ~ 43872889 (-) |
XLOC_026702 | BX682557.2 | coding | upstream | 180316 | 43866785 ~ 43875129 (-) |
XLOC_026703 | BX682557.1 | coding | upstream | 191987 | 43878456 ~ 43889443 (-) |
XLOC_026691 | CABZ01079183.1 | non-coding | downstream | 712775 | 42866083 ~ 42866200 (-) |
XLOC_026690 | NA | non-coding | downstream | 832191 | 42548944 ~ 42746784 (-) |
XLOC_026689 | NA | non-coding | downstream | 1205376 | 42371784 ~ 42373599 (-) |
XLOC_026708 | NA | non-coding | upstream | 425076 | 44111545 ~ 44124370 (-) |
XLOC_026709 | NA | non-coding | upstream | 646278 | 44332747 ~ 44335853 (-) |
XLOC_026716 | NA | non-coding | upstream | 1853317 | 45539786 ~ 45543451 (-) |