alas2 (alas2)


Basic Information

Item Value
gene id alas2
gene name alas2
gene type coding
species rainbow trout (Oncorhynchus mykiss)
category of species economic fish

Chromosome Information

Item Value
chromosome id NC_048573.1
NCBI id CM023227.2
chromosome length 79455637
location 46305459 ~ 46317525 (-)
genome version USDA_OmykA_1.1_2020_rainbow_trout_Genome

Sequence

>XM_021615925.2
CAACGTATGGGTGTGAACAAGAATAATTTTCGAAGAATTGCTGACAACGTCACTGCCCGAACTTTTGACGACAGATACATCTCTGTCTATTACTGTTTTGAAGTTCGTCCTCAGTGCAGGTCAACAGATTCAAAACTGCTTCAAGAGCCATGGCCGCTTTCCTTCACCACTGCCCCTTCCTGAAGTCGGCCCCCAAGCCTGTTTTGCTGAAAACTGGGGCCGCACTCCTCTCTATGGCCGACCGATGCCCCATGATCGTCCGCCAGATCACTGTTTGTGCCTCAATCCCCAAGGAGAGGAAGACGACCATCCATTCTACCCAGTCAGCAGGCATCCTGCCCCTGAGTGTGGACTCAAAGCGTCATTTTGCCCAATCAGCAACCCAGGTGGCTGTCTCCATGTCCAAGGGATGTCCCTTTGTCTCCAATCAGATTGGCATGGTAAGAGCGAGCCCTGAGGTTCAGGAGGACGTCCCGACGGAGTCTAACCCAGGTATGAAAAGATCTCTTTTGAAGGAACTCGAGGACTCCGTCATGCCGAAGGTCCAAACCCCCAGAGTGTCCCACCTCCTGAAGGACAATATAGTGGGCCCCAGTTTCGACTACGATGGCTTCTTCGACAGGACGATCTCTGAGAAGAAGAACGACCACACCTACCGCATCTTTAAGACAGTGAATCGGCGAGCTGACGTCTTTCCCTTTGCCGAAGACTACTCCATGGCCGGGCGGGAAGGCTCCCAGGTGTCTGTCTGGTGCAGTAACGACTACCTGGGCATGGGTAGCCACCCCCGGGTCCTCAACGGAATTCAGGATGCCCTGAAGAGGCATGGCGCAGGTGCCGGAGGTACCAGGAACATCTCTGGCACCAGTAACTTCCATGTGCTGCTGGAAAAAGAACTGTCCCAGCTCCACCAGAAAGACGGAGCTTTGGTCTTCTCATCCTGCTTCGTTGCCAACGACTCCACCCTCTTCACCCTGGCCAAAATGCTGCCAGGCTGTGAGATATACTCTGACATGGGGAACCACGCTTCAATGATCCAGGGCATAAGGAACAGCGGCGCCAAACGCTTCATCTTCCGCCATAATGACAGCCAACACCTGGAGGAACTGCTGAGTGGCTCCGACCCCAAGACACCCAAAATCGTGGCCTTTGAGACCGTGCACTCCATGGATGGTGCTATATGTCCCCTGGAGGAGCTATGTGATGTGGCCCATCGCTATGGGGCCTTGACGTTTGTTGATGAGGTCCATGCTGTGGGCCTGTATGGAGCCCACGGGGccggtgtgggagagagagacaacatcatgCACAAGATTGACATTGTCTCTGGAACCTTGGGTAAAGCCTTTGGCTGCGTGGGGGGCTACATTGCCAGTAGCGCTTCCCTGGTGGACACGGTGCGTTCCTTCGCTGCAGGTTTCATCTTCACTACTTCGCTGCCCCCCATGGTGCTGGCTGGGGCCCTGGAGTCTGTGAGAGTCCTGAAGAGCTCCGAGGGCCAGGCGCTGCGCAGGGCCCACCAGAGGAATGTCAAACACATGAGACAGCTGCTCCTGGAGAAGGGACTGCCTGTGGTCAACTGCCCCAGCCACATCATCCCAATAAAGGTTGGTAACGCGGAGCTCAACTCCAAGGTGTGTGACATCTTGCTGGAGCGACACAACATCTACGTCCAGGCCATCAATTACCCGACAGTAGCCCGAGGCGAGGAGCTGCTGCGTCTGGCTCCCTCCCCTCACCACAACCCTGCAATGATGGAGTACTTTGTGGAGAGGCTCGTGGAGGTGTGGCAAGAAACGGGGCTCCTTCTGAACGGGCCGGCGACTGTCTCCTGCACCTTCTGTGATCGCCCACTGCACTTTGACCTGATGAGTGAGTGGGAGAAATCCTACTTTGGCAACATGGAGCCTCAATACATCACTGTGTCCGCATAGTACAAAACTCCATTCATTATACATCATTATCATCACATCATTGCTCTTATTTCATACCAGGTTTCATTCAAACAACGTACATATTATGTAGACTACACATTTTAATCTTATCTCATTCAgtatttattttctgtgtttaTTGTTTCTAAAGTAACTTGCTATCCCCAAAATATTTAAGATTACATTCATAATTCCGTGAACTAAAATGTGTGCCCCTTTCACATAGTGACTTAAAACATAAAACCTGCACATGGGCACTTTCTAAAATAACAACTTAATCTCAAGGTGATATTTTGGATTGTATAGATTTCTATATCAATTGTCTTGTGCTTTGGTCACCCGTAATAGTGAAAGACCACAATCATGAGTTGTCTCACTGAAATGTCATTGAAACTGAAAATATGAAATAGAATCACTATTCAACTTGAATGTAACAAAttgaatgtaaaaataaaaatactgctGTAGAAGCGATTTGGTTTATTACACAGGAattcaaaaatacaaaaaaataaattgaaataaaacaaaaa
>XM_036988152.1
CAACGTATGGGTGTGAACAAGAATAATTTTCGAAGAATTGCTGACAACGTCACTGCCCGAACTTTTGACGACAGATACATCTCTGTCTATTACTGTTTTGAAGTTCGTCCTCAGTGCAGGTCAACAGATTCAAAACTGCTTCAAGAGCCATGGCCGCTTTCCTTCACCACTGCCCCTTCCTGAAGTCGGCCCCCAAGCCTGTTTTGCTGAAAACTGGGGCCGCACTCCTCTCTATGGCCGACCGATGCCCCATGATCGTCCGCCAGATCACTGTTTGTGCCTCAATCCCCAAGGAGAGGAAGACGACCATCCATTCTACCCAGTCAGCAGGCATCCTGCCCCTGAGTGTGGACTCAAAGCGTCATTTTGCCCAATCAGCAACCCAGGTGGCTGTCTCCATGTCCAAGGGATGTCCCTTTGTCTCCAATCAGATTGGCATGGTAAGAGCGAGCCCTGAGGTTCAGGAGGACGTCCCGACGGAGTCTAACCCAGGTATGAAAAGATCTCTTTTGAAGGAACTCGAGGACTCCGTCATGCCGAAGGTCCAAACCCCCAGAGTGTCCCACCTCCTGAAGGACAATATAGTGGGCCCCAGTTTCGACTACGATGGCTTCTTCGACAGGACGATCTCTGAGAAGAAGAACGACCACACCTACCGCATCTTTAAGACAGTGAATCGGCGAGCTGACGTCTTTCCCTTTGCCGAAGACTACTCCATGGCCGGGCGGGAAGGCTCCCAGGTGTCTGTCTGGTGCAGTAACGACTACCTGGGCATGGGTAGCCACCCCCGGGTCCTCAACGGAATTCAGGATGCCCTGAAGAGGCATGGCGCAGGTGCCGGAGGTACCAGGAACATCTCTGGCACCAGTAACTTCCATGTGCTGCTGGAAAAAGAACTGTCCCAGCTCCACCAGAAAGACGGAGCTTTGGTCTTCTCATCCTGCTTCGTTGCCAACGACTCCACCCTCTTCACCCTGGCCAAAATGCTGCCAGGCTGTGAGATATACTCTGACATGGGGAACCACGCTTCAATGATCCAGGGCATAAGGAACAGCGGCGCCAAACGCTTCATCTTCCGCCATAATGACAGCCAACACCTGGAGGAACTGCTGAGTGGCTCCGACCCCAAGACACCCAAAATCGTGGCCTTTGAGACCGTGCACTCCATGGATGGTGCTATATGTCCCCTGGAGGAGCTATGTGATGTGGCCCATCGCTATGGGGCCTTGACGTTTGTTGATGAGGTCCATGCTGTGGGCCTGTATGGAGCCCACGGGGccggtgtgggagagagagacaacatcatgCACAAGATTGACATTGTCTCTGGAACCTTGGcTTGTCACAGAGCTAGGGAAATGCCCCTCACAGCAGAGAGAGATTTGATTGAGCCAAGTAAAGCCTTTGGCTGCGTGGGGGGCTACATTGCCAGTAGCGCTTCCCTGGTGGACACGGTGCGTTCCTTCGCTGCAGGTTTCATCTTCACTACTTCGCTGCCCCCCATGGTGCTGGCTGGGGCCCTGGAGTCTGTGAGAGTCCTGAAGAGCTCCGAGGGCCAGGCGCTGCGCAGGGCCCACCAGAGGAATGTCAAACACATGAGACAGCTGCTCCTGGAGAAGGGACTGCCTGTGGTCAACTGCCCCAGCCACATCATCCCAATAAAGGTTGGTAACGCGGAGCTCAACTCCAAGGTGTGTGACATCTTGCTGGAGCGACACAACATCTACGTCCAGGCCATCAATTACCCGACAGTAGCCCGAGGCGAGGAGCTGCTGCGTCTGGCTCCCTCCCCTCACCACAACCCTGCAATGATGGAGTACTTTGTGGAGAGGCTCGTGGAGGTGTGGCAAGAAACGGGGCTCCTTCTGAACGGGCCGGCGACTGTCTCCTGCACCTTCTGTGATCGCCCACTGCACTTTGACCTGATGAGTGAGTGGGAGAAATCCTACTTTGGCAACATGGAGCCTCAATACATCACTGTGTCCGCATAGTACAAAACTCCATTCATTATACATCATTATCATCACATCATTGCTCTTATTTCATACCAGGTTTCATTCAAACAACGTACATATTATGTAGACTACACATTTTAATCTTATCTCATTCAgtatttattttctgtgtttaTTGTTTCTAAAGTAACTTGCTATCCCCAAAATATTTAAGATTACATTCATAATTCCGTGAACTAAAATGTGTGCCCCTTTCACATAGTGACTTAAAACATAAAACCTGCACATGGGCACTTTCTAAAATAACAACTTAATCTCAAGGTGATATTTTGGATTGTATAGATTTCTATATCAATTGTCTTGTGCTTTGGTCACCCGTAATAGTGAAAGACCACAATCATGAGTTGTCTCACTGAAATGTCATTGAAACTGAAAATATGAAATAGAATCACTATTCAACTTGAATGTAACAAAttgaatgtaaaaataaaaatactgctGTAGAAGCGATTTGGTTTATTACACAGGAattcaaaaatacaaaaaaataaattgaaataaaacaaaaa

Function

symbol description
alas2 Predicted to enable 5-aminolevulinate synthase activity. Acts upstream of or within heme biosynthetic process; hemoglobin biosynthetic process; and hemopoiesis. Predicted to be located in mitochondrial inner membrane. Predicted to be active in mitochondrion. Is expressed in erythroid progenitor cell; hematopoietic system; mesoderm; and pronephric duct. Used to study sideroblastic anemia. Human ortholog(s) of this gene implicated in cutaneous porphyria; erythropoietic protoporphyria; hemochromatosis; sideroblastic anemia; and sideroblastic anemia 1. Orthologous to human ALAS2 (5'-aminolevulinate synthase 2).

NR:

description
5-aminolevulinate synthase, erythroid-specific, mitochondrial-like

GO:

id name namespace
GO:0006782 protoporphyrinogen IX biosynthetic process biological_process
GO:0035162 embryonic hemopoiesis biological_process
GO:0020027 hemoglobin metabolic process biological_process
GO:0005759 mitochondrial matrix cellular_component
GO:0003870 5-aminolevulinate synthase activity molecular_function
GO:0030170 pyridoxal phosphate binding molecular_function

KEGG:

id description
K00643 E2.3.1.37, ALAS; 5-aminolevulinate synthase

RNA

RNA id representative length rna type GC content exon number start site end site
XM_021615925.2 False 2467 mRNA 0.50 10 46305459 46317525
XM_036988152.1 True 2524 mRNA 0.50 11 46305459 46317525

Neighbor

gene id symbol gene type direction distance location
LOC110532215 LOC106572154 coding downstream 41625 46256999 ~ 46263834 (-)
LOC110532213 emp3 coding downstream 98755 46202726 ~ 46206704 (-)
zmynd12 zmynd12 coding downstream 105209 46187156 ~ 46200250 (-)
LOC110532208 LOC106572161 coding downstream 264194 45816274 ~ 46041265 (-)
tmem51a LOC106572162 coding downstream 499595 45793209 ~ 45805864 (-)
LOC110532223 LOC100380856 coding upstream 75576 46393101 ~ 46525481 (-)
LOC110531189 pigt coding upstream 327265 46644716 ~ 46656973 (-)
LOC110532229 sycp2 coding upstream 402037 46719562 ~ 46781807 (-)
LOC110533016 sycp2 coding upstream 464283 46781808 ~ 46783939 (-)
prdm2a LOC106572143 coding upstream 484063 46801588 ~ 46819009 (-)
G810596 NA non-coding downstream 1046 46304137 ~ 46304413 (-)
G810595 NA non-coding downstream 2498 46302723 ~ 46302961 (-)
G810563 NA non-coding downstream 48537 46253514 ~ 46256922 (-)
G810560 NA non-coding downstream 52531 46250051 ~ 46252928 (-)
G810623 LOC106572152 non-coding upstream 27149 46344674 ~ 46346295 (-)
G810638 NA non-coding upstream 47851 46365376 ~ 46371475 (-)
G810649 NA non-coding upstream 72093 46389618 ~ 46392134 (-)
G810762 NA non-coding upstream 254267 46571792 ~ 46571991 (-)
G810788 NA non-coding upstream 287413 46604938 ~ 46607793 (-)
pdyn pdyn other downstream 986693 45316564 ~ 45318766 (-)
G809071 LOC106572179 other downstream 1007609 45295856 ~ 45298740 (-)
G808375 NA other downstream 1668613 44634559 ~ 44636846 (-)
G811300 NA other upstream 861279 47178804 ~ 47181797 (-)
LOC110531190 clcn6 other upstream 1345540 47642136 ~ 47676649 (-)
LOC110532252 fkb1a other upstream 1960649 48278174 ~ 48286453 (-)
G812840 NA other upstream 2191120 48508645 ~ 48509094 (-)
G813357 LOC106578276 other upstream 2597910 48915435 ~ 48915704 (-)

Expression


Co-expression Network