XLOC_026742 (ARHGAP44)


Basic Information

Item Value
gene id XLOC_026742
gene name ARHGAP44
gene type coding
species zebrafish (Danio rerio)
category of species model fish

Chromosome Information

Item Value
chromosome id NC_007114.7
NCBI id CM002887.2
chromosome length 62628489
location 48638594 ~ 48716422 (-)
genome version GRCz11_2017_zebrafish_Genome

Sequence

>TCONS_00052066
ATTCCTCCTCTTGCTAGAACtgcttataaatgtgtttttctcCAATTTAACAGGGCAGAAAAAACTGAGGTACTTAGTGAAGACCTGCTACAGGTGGAGAAGCGTTTGGACCTGGTGAAACAGGTCTCTCATAGCACACATAAGAAGCTCACAGCATGTCTACAGGGTCAACAAGGCACAGAAATAGAAAAGAGATCTGTCAAATCACCTTCGAAAAAGCTTCCACTGACTACACTTGCTCAATGTATGGTGGAGGGAGCTGCTGTTTTAGGAGACGACTCTCTACTTGGCAAGATGCTGAAGCTCTGTGGAGATACAGAGGAGAAGTTGGCCCAAGAGCTGCTCGTCTTTGAGCTTCAGATTGAAAGAGATGTCGTGGAGCCTCTTTATGTGCTGGCTGAGGTGGAAATTCCGAACATTCAGAAACAGCGAAAACATTTAGCCAAACTTGTTCTAGACATGGATTCTGCAAGGACACGGTGGCAACAATCATCCAAGTCTTCAGGTCACCCTAGTAACGTGCAGCAGGGTGGAGCCAAGTCTGATTCCCTGAGGGAGGAAATGGAGGAGACGGCCAATCGGATGGAGATCTGCAGGGACCAGTTATCAGCGGACATGTACAACTTTGTGGCCAAAGAAATAGACTATGCAAACTACTTTCAAACGCTCATTGAGGTTCAGGCCGAGTACCACAGGAAGTCTCTGGAGATCCTGCAGAGTGTCCTGCCGCAGATCAAAGCTCACCAGGAGGCCTGGATAGAGAAGCCATCGTATGGGAAGGCCTTAGAGGAACATCTAGCCATCAGCGGCAGGGAGATTGCCTTTCCTATCGAGGCTTGCGTCACCATGCTGCTCGAATGTGGCATGCAGGAAGAGGGTTTATTTCGAGTGGCTCCCTCTGCCTCCAAACTGAAGAAGCTGAAAGCGTCGCTGGACTGTGGCGTTATGGATGTGCAAGAATACTCAGCCGACCCGCACGCCATCGCCGGGGCGTTAAAGTCTTATCTCCGTGAGCTTCCTGAACCTCTAATGACATTTGAGCTCTATGATGAATGGATTCAAGCCTCAAATATTCAGGATATGGACAAAAGGCTTCAAGCCCTGTTGTGTACATGTGAGAAACTACCAGCAGACAATCTGAACAACTTCAGATATTTAATCAAATTCTTATCCAAACTCACAGAGTACCAAGACTCTAATAAAATGACACCAGGCAACATTGCAATAGTTCTCGGACCCAACCTGCTGTGGACACATTCAGAAGGGAACATGACAGAAATGATGACCACCATGTCCCTGCAAATCGTAGGAATCATTGAGCCGATCATCCAGCACGCGGACTGGTTCTTCCCTGGAGAAATTGAGTTCAACCTGACAGGCAGCTACGGCAGCCCAGTGCACACCAACCACAACTCCAACTACAGCTCCATGCCCTCACCAGATATGGACCAATCAGAGCGCAAGCAGCAGCACGACCAGAGCCGACGCCCACTCAGCGTTGCCACCGACAACATGATGCTGGAGTTCTACAAGAAGGACGGTTTGTGTTTTCATGTGGACAGTGTGGGTGTCAGAGTCATGGACACCTCATGGGTGAAAGGCAAAAGCACCTCTACACTTTCCCGTAAATCCTCATCCACACCTCCCAGTGGTCAACCacctggatcaccagcagacacACTGATCTCAGAGCAGGCTGGTGAGCTGGCAACATCTCCAATCCCGACCCCCCCTCCTGGAGACAGGGGCAGCTCAGACGACGTGTCGCCCAATCGGCCGGATTCCTCACATGTCTATGTGTCCCACGTGGAGGAGCGGCCACCCCCTCCGTACCCTTCCTCGTCCTCCCATCCCGGCCCTCACCATTTCTACCCCAAGCCCCCTCCCTGCGCTCGTCCTGTGGCCCCTGGCCCAGAGTCCCAGCCACCTGCCTCTCCGCCTCCACCCCTGCGGTGGTCTGGCTTTCACCAGCCTCAGCCCCAGCTACCACccccttcctcctcctcctcctcctcctcttgctCACTCGATATCAACTCCAACCCCAAGCCTAGCTGCCTGCACTTTCCCAAACACGGCCCTGTGTGTGACGCACCGCATGCCTCTATGCTCCATGACGTCAATTCTTCGCCCCTCTACATTAAAACCCCTCTCGTGCTGACCCGCCACGACCCCCCTAGCCTCCCCTCTTCCGCTCCCCCGCCGTGGGCTGCCTGTCCATGTGCCCGTGAGAGAGGACCCCCCAGGCTGACTAGtaCTCTGAAGAGTAAGGAACTCTCTCCTGTGATTGGCCACAAGGCTGTGCAGGCGTCAGGATCAACAGTGCCCCCTGTCGGCGGCCAGCAGAGCAACAGCCAGTCTCCACACTCGGCCGAGCACAGCCCACACACCTTACGCAAAGTGTCTAAGAAATTGGCCCCTGTGCCGCCCAAGGTTCCCTACGGCCAGTCGGGGGGGATGTCAGACCAATCCACAGGTCAGCCGTCTCCGGTTAGCCTGTCCCCCACTCCCCCAAGTACCCCCTCCCCTTACGGTTTGGGCTGTCCCCCTGGACATGCGCCCACCTCTTCCCCTGGCCAGACCCCATTAGGGGGACCCCATACACTGTCCTCACCACCAACTTCTCTGACTGGTACGCTCACAAAGTCCCGGCCCAACCCAAAGCCCAGGCAGAGACCCAGTCTGCCCCCTCCCCAGCCGCCCACCGTGCCCCCTACGGTCCCCCAGCCCCTGGAGCAGGGTCTACTTGACGGATTATCCCCCGGAGAGAGCATGTCCACAGGTAAACATGCCTCAGTGGCACCATCACGATTGGGAGTCCAGCGTCCCTCTCTCAAACTGTCTGTCTCTCCGTCCTACGCAGGCGATGGACTTTAA

Function

symbol description
arhgap44 Enables phospholipid binding activity. Predicted to be involved in several processes, including modification of dendritic spine; negative regulation of Rac protein signal transduction; and regulation of plasma membrane bounded cell projection organization. Located in leading edge membrane.

GO:

id name namespace
GO:0035020 regulation of Rac protein signal transduction biological_process
GO:0035021 negative regulation of Rac protein signal transduction biological_process
GO:0098886 modification of dendritic spine biological_process
GO:0098887 neurotransmitter receptor transport, endosome to postsynaptic membrane biological_process
GO:0032956 regulation of actin cytoskeleton organization biological_process
GO:0061001 regulation of dendritic spine morphogenesis biological_process
GO:0007165 signal transduction biological_process
GO:0031256 leading edge membrane cellular_component
GO:0048786 presynaptic active zone cellular_component
GO:0005622 intracellular anatomical structure cellular_component
GO:0014069 postsynaptic density cellular_component
GO:0043197 dendritic spine cellular_component
GO:0005737 cytoplasm cellular_component
GO:0005096 GTPase activator activity molecular_function

KEGG:

id description
ko04131 Membrane trafficking

ZFIN:

id description
ZDB-GENE-120206-2 Predicted to enable GTPase activator activity. Predicted to be involved in several processes, including modification of dendritic spine; negative regulation of Rac protein signal transduction; and neurotransmitter receptor transport, endosome to postsynaptic membrane. Predicted to act upstream of or within signal transduction. Predicted to be located in cytoplasm. Predicted to be active in several cellular components, including dendritic spine; leading edge membrane; and postsynaptic density. Orthologous to human ARHGAP44 (Rho GTPase activating protein 44).

Ensembl:

ensembl_id ENSDARG00000102424

RNA

RNA id representative length rna type GC content exon number start site end site
TCONS_00052066 True 2877 mRNA 0.55 20 48638594 48716422

Neighbor

gene id symbol gene type direction distance location
XLOC_026741 ndel1b coding downstream 26516 48584684 ~ 48612078 (-)
XLOC_026740 atp5pd coding downstream 78688 48549294 ~ 48559906 (-)
XLOC_026739 NA coding downstream 164840 48461497 ~ 48473754 (-)
XLOC_026738 NA coding downstream 310461 48323540 ~ 48328133 (-)
XLOC_026737 znf750 coding downstream 379305 48253202 ~ 48259289 (-)
XLOC_026743 BX769173.3 coding upstream 249501 48965923 ~ 48980319 (-)
XLOC_026744 BX769173.1 coding upstream 270249 48986671 ~ 48993580 (-)
XLOC_026745 NA coding upstream 283481 48999903 ~ 49001293 (-)
XLOC_026746 BX769173.2 coding upstream 294565 49010987 ~ 49015203 (-)
XLOC_026747 NA coding upstream 307478 49023900 ~ 49036782 (-)
XLOC_026736 NA non-coding downstream 805480 47827202 ~ 47833114 (-)
XLOC_026732 NA non-coding downstream 1441634 47194738 ~ 47196960 (-)
XLOC_026731 NA non-coding downstream 1507483 47130032 ~ 47131111 (-)
XLOC_026748 BX784040.1 non-coding upstream 361340 49077762 ~ 49077879 (-)
XLOC_026752 NA non-coding upstream 469976 49186398 ~ 49372676 (-)
XLOC_026754 NA non-coding upstream 689736 49406158 ~ 49418345 (-)

Expression


Co-expression Network

Homologous

species gene id symbol gene type chromosome NCBI id location
bowfin (Amia calva) AMCG00013296 NA coding CM030125.1 CM030125.1 27548805 ~ 27569295 (+)