XLOC_026756 (prkacaa)


Basic Information

Item Value
gene id XLOC_026756
gene name prkacaa
gene type coding
species zebrafish (Danio rerio)
category of species model fish

Chromosome Information

Item Value
chromosome id NC_007114.7
NCBI id CM002887.2
chromosome length 62628489
location 49459828 ~ 49504023 (-)
genome version GRCz11_2017_zebrafish_Genome

Sequence

>TCONS_00052076
AGCTGTGGAGAGAGGATTAATGGAGGGGGTCTGACTGTCGAATTATGCGAACTACATAGTGCACAAGACCGAATTGCTTTAACAACGTAAACAAGCAAACGATCACGCTACCGAAAAGGTACGGCGAAGACGGCGTGCAGCGATAGAAATCGCGCACGGACGGTGAAAACGAGGGCTTGTGTCGCTCAAGAGGAAAGTCGAGGGCCTCGCTCAGGGTTAGCAGAGCGAGGAAGAGGAGCGAGAGAAGGAGAAGAAGACGGGCTCTTCGTCTTATTTTAGCGGACTGGACCCGACCCAGGAGCACTGAAGGACATTACCGAACCCCAAGCGCTGCAATCAGACAGCTACTGTTAGCTAGCTAGCGCTGGCTAGCTAGCTAACCAACTAACCAGCTACTATCATCAAGCTTCAGACTTTATGTGATCTGACAGCATACTGTGATCCAGCGAGTTATGATCAGACACAGCTAGTGCGACGCCCGCAGAAATCGTATGATCAGCAAGGGGACGGAGTCTTAAGACAGTTGGCGTAAAGAAAAGTCGATTTAGATCTGCTATACCTGGCCTGCAATCATGGGCAACGCGCCCACCGCCAAGAACAAGGGCAATGAGATGGAGAGCGTTAAGGAGTTTCTCGCTAAAGCCAAAGAAGATTTCCTAAAGAAATGGGAGAACCCAGCACAGAACACTGCGTCTCTGGACCATTTTGAGCGGTTGAAGACGCTGGGCACCGGCTCCTTTGGACGAGTCATGCTAGTCAAGCACAAAGAATCAGGCCAGCATTTTGCCATGAAGATCCTCGACAAACAGAAGGTGGTGAAGCTGAAACAGATAGAACACACACTGAATGAGAAACGCATCCTGCAGGCTGTCAGCTTCCCCTTTCTTGTGCGATTGGAGCATTCTTTCAAGGATAATACTAACCTGTATATGGTAATGGAGTATGTTCCTGGAGGAGAGATGTTTTCTCACTTACGTAGAATCGGAAGATTTagTGAGCCTCATGCCCGATTTTACGCCGCCCAAATAGTTCTGACCTTTGAATACCTTCACTCACTCGATCTCATCTACCGAGATCTGAAGCCTGAAAACCTGCTCATAGACCAGCAGGGCTACATACAGGTAACAGATTTTGGATTTGCTAAACGTGTAAAGGGCAGGACCTGGACACTGTGTGGCACACCTGAGTACCTGGCACCAGAAATCATCCTCAGTAAAGGCTATAATAAAGCTGTGGACTGGTGGGCTCTGGGAGTGCTGATCTACGAGATGGCTGCTGGTTACCCGCCATTCTTTGCTGACCAGCCTATCCAGATCTACGAGAAAATTGTCTCCGGGAAGGTCCGCTTTCCTTCACATTTTAGCTCTGACCTGAAGGATCTGCTGAGAAACCTGCTGCAGGTCGATCTGACGAAACGCTTCGGGAACCTGAAGAACGGCGTCAACGACATCAAGGGCCACAAATGGTTTGCAACCACCGACTGGATTGCAATCTACCAGAAGAAGGTGGAAGCCCCGTTCATCCCTAAGTGCAAAGGCCCCGGGGACACCAGCAACTTCGACGACTACGACGAGGAAGAAATCCGGGTCTCTATCACGGAGAAATGTGGAAAGGAGTTTGCTGAATTctagaagcagcagcagcagcggtgGAGGAGAGGCATGGAGAGAGATTAGACGTGGGGCAACAGAGAGAAGAAGAAGACAAGGATGAGGTTTTCCAGGTTGGGATGATGGACTGGACTGAGCCTGTATTCGGTAACAACAACGCAAAGCCCTCACACACAGACGGAGGGAGAATAGGAGTCCtgagagataaagagagagagagagacgccaGCGGTGTTGCCTTTTCAGATCCTTCGTCACTTGTTACTTGTCCATTTTCATGTTTTCCCTCTTGTTTGGTAGCCAGGGTCCATTGGGCAGAGATTCAGTCACCTCTCTGGGACTGGCTGGCATGGGGATATTTGtgactacttttttttttgtttgtttgtttttttctccagAGATATAGAGGTTACTTTCTGGTACTGAATTTTGGCTTCTCCAGAGAAAATTACCCCATAttacttcaatttttttttaattagcaaagGTGTCCTTGCTCTGTAGTTATCCACTCTTTCACATAttcttttcattattttaatttccaaTGCACATATTGGCACTCAATACCAAATCAAACCAACTG

Function

symbol description
prkacaa Predicted to enable protein kinase A regulatory subunit binding activity. Predicted to be involved in protein kinase A signaling. Predicted to act upstream of or within protein phosphorylation. Predicted to be active in nucleus. Is expressed in fin bud; hatching gland; nervous system; otic vesicle; and presumptive neural retina. Human ortholog(s) of this gene implicated in adrenal cortical adenoma; congestive heart failure; and primary pigmented nodular adrenocortical disease. Orthologous to human PRKACA (protein kinase cAMP-activated catalytic subunit alpha).

GO:

id name namespace
GO:0071333 cellular response to glucose stimulus biological_process
GO:0010737 protein kinase A signaling biological_process
GO:0006468 protein phosphorylation biological_process
GO:0016310 phosphorylation biological_process
GO:0005634 nucleus cellular_component
GO:0016740 transferase activity molecular_function
GO:0005524 ATP binding molecular_function
GO:0034237 protein kinase A regulatory subunit binding molecular_function
GO:0000166 nucleotide binding molecular_function
GO:0004672 protein kinase activity molecular_function
GO:0004674 protein serine/threonine kinase activity molecular_function
GO:0004691 cAMP-dependent protein kinase activity molecular_function
GO:0016301 kinase activity molecular_function

KEGG: NA

ZFIN:

id description
ZDB-GENE-050114-6 Predicted to enable protein kinase A regulatory subunit binding activity. Predicted to be involved in protein kinase A signaling. Predicted to act upstream of or within protein phosphorylation. Predicted to be active in nucleus. Is expressed in fin bud; hatching gland; nervous system; otic vesicle; and presumptive neural retina. Human ortholog(s) of this gene implicated in adrenal cortical adenoma; congestive heart failure; and primary pigmented nodular adrenocortical disease. Orthologous to human PRKACA (protein kinase cAMP-activated catalytic subunit alpha).

Ensembl:

ensembl_id ENSDARG00000100349

RNA

RNA id representative length rna type GC content exon number start site end site
TCONS_00052076 True 2199 mRNA 0.48 10 49459828 49504023

Neighbor

gene id symbol gene type direction distance location
XLOC_026755 samd1a coding downstream 11879 49425793 ~ 49447949 (-)
XLOC_026754 NA coding downstream 41483 49406158 ~ 49418345 (-)
XLOC_026753 si:ch73-167f10.1 coding downstream 76932 49379774 ~ 49382896 (-)
XLOC_026752 NA coding downstream 87152 49186398 ~ 49372676 (-)
XLOC_026751 dnajb1a coding downstream 296145 49150822 ~ 49163683 (-)
XLOC_026757 asf1ba coding upstream 896 49504919 ~ 49514874 (-)
XLOC_026758 CR847534.1 coding upstream 47557 49551580 ~ 49554912 (-)
XLOC_026759 zgc:153426 coding upstream 55238 49559261 ~ 49566364 (-)
XLOC_026760 gcgra coding upstream 253555 49757578 ~ 49925313 (-)
XLOC_026761 NA coding upstream 430613 49934636 ~ 49937735 (-)
XLOC_026748 BX784040.1 non-coding downstream 381949 49077762 ~ 49077879 (-)
XLOC_026747 NA non-coding downstream 423046 49023900 ~ 49036782 (-)
XLOC_026745 NA non-coding downstream 458535 48999903 ~ 49001293 (-)
XLOC_026769 NA non-coding upstream 834757 50338780 ~ 50341046 (-)
XLOC_026770 NA non-coding upstream 929528 50433551 ~ 50438278 (-)
XLOC_026771 NA non-coding upstream 929770 50433793 ~ 50434423 (-)
XLOC_026773 CR812464.1 non-coding upstream 1224836 50728859 ~ 50749116 (-)

Expression


Co-expression Network

Homologous

species gene id symbol gene type chromosome NCBI id location
grasscarp (Ctenopharyngodon idella) CI01000033_01312689_01320687 PRKACAA, PRKACA.L, PRKACA, KAPCA coding CI01000033 null 1312626 ~ 1320687 (-)