XLOC_026810 (s1pr2)


Basic Information

Item Value
gene id XLOC_026810
gene name s1pr2
gene type coding
species zebrafish (Danio rerio)
category of species model fish

Chromosome Information

Item Value
chromosome id NC_007114.7
NCBI id CM002887.2
chromosome length 62628489
location 54616015 ~ 54669185 (-)
genome version GRCz11_2017_zebrafish_Genome

Sequence

>TCONS_00052143
gcgtgtattaCGTCGCCTGTTCAGATCGAGAGAGGCTGCTGCTTGTCGACGAGCGCGTGGATTTTACATATCTGTGAATTAAACGGGAAATACAAGTAACTGCTGCGTCGTTAACTCAAACCAAGAGTGTTTATCtcgcttttttttaatgtttatccGAGCCATGGCTGTATTAGTGATCAGATATGCAGCAGTCACTCCGCAAAAGTTTTgacttttattaaatctgttgaaTTTCTGGAGCTCTCGCGAACGGATCCTTGAAGACTCGACCAAGCCATCAGGAATTAAGGAATCTCATGTAAACTTTGTAAATGAAGATTAAAAACATCTGCACGCGCTTCTTCTCTCCGCCGGCACATGGGGTGACACAGAGGAGCTTCCTGGGCCGCTGAGACGTGACTTCGGGCTGGGCGTCTCATTTCCTGTGCCTGGCCCAGACAAGCTCAAAAAAAAGCTGCCCTCTGAATGACTACTTGCCGTCTGTTTGCGGGGTTTTGCCAAGCTGTCACCATGAGCAAATACTCCCAGTACTTCAACAAGACCCTCATCCAGGTCCACTATCTCACTGCTAAGGAGATGACCGCAGAGGAACTAAGAGACCGCATCGAGAGCAAACAAAGCTTGAGCTCCCTGAACATTTTATTTGTCGTAATCTGCAGCATCATCATCTTGGAAAACCTCCTAGTGCTCATCGCTGTGTTTAGGAATAAAAAGTTCCACTCAGCCATGTTCTTCTTCATTGGGAACCTGGCCTTCTCGGACCTACTAGCTGGCTCTGCATACATTGCCAACATCTTCCTGTCTGGCCCTAGGACATTTCATTTGACTCCTGTCCAGTGGTTCATACGAGAGGGGACTGCTTTCATTGCTTTGTCCGCCTCCGTTTTCAGCCTGCTGGCTATTGCTATCGAGCGCTACATCGCCATCACCAAGGTCAAGGTTTACGGATCCAACAAAACGTGCCGCATGTTTCTTCTGATCGGAGCATGCTGGGTGATGTCCATTCTTCTAGGAGGTCTTCCTATTATAGGTTGGAACTGTATTAATAACCTGGATGATTGCTCAGCTGTTTTGCCCCTCAACACCCGATACTACATCCGGTTTGTTGTCACCATCTTTAGCATCATCTTGCTGTCCATCGTGATCCTTTACGTTCGCATCTATCTCATTGTGCGCACCAGCCACCAAGAGGCCACCAATTCTCCAGCGTATGCTCTCCTGAAGACGGTCACAATTGTCCTTGGCGTCTTCATCATCTGTTGGCTGCCTGCCTTCACCATCCTCCTCCTGGACACTTCCTGCAAGATGAAGCAATGCCCTATCCTCAATAACGCTGGCATCTTCTTCAGCTTTGCCACACTGAATTCGGCACTGAACCCGTTGATCTACACCTTGCGGAGTAAGGACATGAGGAAGGAGTTCTTGAGGGTCCTGTGTTGCTGGGGGCTGCTCAATTGCGGCAGACCTCCTCACCGCTGCATGGTACCACTCAAAAGCTCGAGTTCAATGGAGCACTGCACCAACAAACATGAACATCAGTCCATTCCCATCATGCAGGACTGCACTACCTGTGTTTGACTTCGTCTACACAGTGCCCAAGTGTTTGCAGATCCCCCTCTCTTGGAGGCAAGGCACATTCGACAGAAGTGTTCAGAGATCTTGTGGGCCAAACAAGAATCACAACTAATGACTCTTACATTTAGAGCAGATGCCACAGCCGTGTTACCAGACTCCCACTTGTCCTTAGTCGCTTCTATCGTTGCAAAGTTTCCTGATCATCACAGCAGACTTGTCCTGCAAGTGAACCCATCAACAAAGCAAGTGAAAGAAAGCCAAATTGAAATGGGAATATGCATTTTAGCTCTTTGACCAAACATGAACAATCAAAGTTGAAGATATTGCACTTTGTAGACTTGTAGGCGGTTTGGCATTCTGTACTTCTCAAGTGCCGACCAACCTACTAGAAGTCCCAAACAAGATGTATCCTATCCACTGTCATGGTTCTGAAATATAAATGGACAGACTGAAATGTAAAGATCGACAATGCACTCCCAAGTGAGCCAAACCACCATGTACGTTTGCAGAAGCTCTCCTAATGTATTTATCGAATTACTTGATATACGTAACACCCTTTGATTACCAACAGTAAAAGTATTCCACTTCATTGTATTGCATGAAATTCTAACCTGTGTAAAGACTTATATGTATGCCAAGCCTATCTACAGTTGTCAATGTTACTCCTCTATTTCCATCTTGTCCATGTAAAGTCACAGTCCCTTCCTATTTTATTCTTTCTGTTAACATTCCTGTTTCTTCTTAAGAGGAGAACCCAGTCAGTACGTAATTACTGAAATCCTAAAATGAATT

Function

symbol description
s1pr2 Predicted to enable sphingosine-1-phosphate receptor activity. Acts upstream of or within several processes, including embryonic morphogenesis; sensory organ development; and sphingosine-1-phosphate receptor signaling pathway. Predicted to be located in membrane. Predicted to be integral component of membrane. Predicted to be active in cytoplasm and plasma membrane. Is expressed in several structures, including cardiovascular system; midbrain hindbrain boundary neural rod; midbrain hindbrain boundary neural tube; nervous system; and pleuroperitoneal region. Used to study carcinoma. Human ortholog(s) of this gene implicated in autosomal recessive nonsyndromic deafness 68. Orthologous to human S1PR2 (sphingosine-1-phosphate receptor 2).

GO:

id name namespace
GO:0042074 cell migration involved in gastrulation biological_process
GO:0007186 G protein-coupled receptor signaling pathway biological_process
GO:0007189 adenylate cyclase-activating G protein-coupled receptor signaling pathway biological_process
GO:0019222 regulation of metabolic process biological_process
GO:0060872 semicircular canal development biological_process
GO:0007492 endoderm development biological_process
GO:0003376 sphingosine-1-phosphate receptor signaling pathway biological_process
GO:0007507 heart development biological_process
GO:0003143 embryonic heart tube morphogenesis biological_process
GO:0035050 embryonic heart tube development biological_process
GO:0048840 otolith development biological_process
GO:0060973 cell migration involved in heart development biological_process
GO:0048901 anterior lateral line neuromast development biological_process
GO:0035676 anterior lateral line neuromast hair cell development biological_process
GO:0061035 regulation of cartilage development biological_process
GO:0035677 posterior lateral line neuromast hair cell development biological_process
GO:0003007 heart morphogenesis biological_process
GO:0060026 convergent extension biological_process
GO:0060027 convergent extension involved in gastrulation biological_process
GO:0001944 vasculature development biological_process
GO:0030336 negative regulation of cell migration biological_process
GO:0048703 embryonic viscerocranium morphogenesis biological_process
GO:0008078 mesodermal cell migration biological_process
GO:0003315 heart rudiment formation biological_process
GO:0003318 cell migration to the midline involved in heart development biological_process
GO:0003319 cardioblast migration to the midline involved in heart rudiment formation biological_process
GO:0007165 signal transduction biological_process
GO:0005886 plasma membrane cellular_component
GO:0016020 membrane cellular_component
GO:0016021 integral component of membrane cellular_component
GO:0005737 cytoplasm cellular_component
GO:0038036 sphingosine-1-phosphate receptor activity molecular_function
GO:0004930 G protein-coupled receptor activity molecular_function

KEGG:

id description
ko04071 Sphingolipid signaling pathway
ko04080 Neuroactive ligand-receptor interaction
ko04030 G protein-coupled receptors

ZFIN:

id description
ZDB-GENE-020123-2 Predicted to enable sphingosine-1-phosphate receptor activity. Acts upstream of or within several processes, including embryonic morphogenesis; sensory organ development; and sphingosine-1-phosphate receptor signaling pathway. Predicted to be located in membrane. Predicted to be integral component of membrane. Predicted to be active in cytoplasm and plasma membrane. Is expressed in several structures, including cardiovascular system; midbrain hindbrain boundary neural rod; midbrain hindbrain boundary neural tube; nervous system; and pleuroperitoneal region. Used to study carcinoma. Human ortholog(s) of this gene implicated in autosomal recessive nonsyndromic deafness 68. Orthologous to human S1PR2 (sphingosine-1-phosphate receptor 2).

Ensembl:

ensembl_id ENSDARG00000036548

RNA

RNA id representative length rna type GC content exon number start site end site
TCONS_00052143 True 2370 mRNA 0.46 2 54616015 54669185

Neighbor

gene id symbol gene type direction distance location
XLOC_026809 dnmt1 coding downstream 8849 54591218 ~ 54607166 (-)
XLOC_026808 angptl6 coding downstream 71403 54524227 ~ 54544612 (-)
XLOC_026807 si:ch73-208g10.1 coding downstream 91821 54502350 ~ 54524194 (-)
XLOC_026806 trip10a coding downstream 115661 54431093 ~ 54500354 (-)
XLOC_026805 NA coding downstream 773231 53842532 ~ 53842784 (-)
XLOC_026811 NA coding upstream 79211 54748396 ~ 54784321 (-)
XLOC_026812 NA coding upstream 122368 54791553 ~ 54820900 (-)
XLOC_026813 ubald1b coding upstream 164473 54833658 ~ 54846444 (-)
XLOC_026814 NA coding upstream 204216 54873401 ~ 54884180 (-)
XLOC_026815 rhbdf1a coding upstream 227146 54896331 ~ 54993027 (-)
XLOC_026804 BX004869.1 non-coding downstream 926587 53689310 ~ 53689428 (-)
XLOC_026802 NA non-coding downstream 1026838 53573131 ~ 53589177 (-)
XLOC_026797 NA non-coding downstream 1163233 53449116 ~ 53452782 (-)
XLOC_026796 NA non-coding downstream 1383520 53230710 ~ 53232495 (-)
XLOC_026831 NA non-coding upstream 1169269 55838454 ~ 55839514 (-)
XLOC_026834 CU855917.1 non-coding upstream 1741956 56411141 ~ 56413023 (-)

Expression


Co-expression Network

Homologous

species gene id symbol gene type chromosome NCBI id location
grasscarp (Ctenopharyngodon idella) CI01000113_00568754_00569821 S1PR2 coding CI01000113 null 568410 ~ 570516 (+)
bowfin (Amia calva) AMCG00008469 s1pr2,LOC106601285,LOC107672500,LOC107711272,LOC107587933 coding CM030126.1 CM030126.1 1935304 ~ 1936419 (-)