XLOC_026816 (nprl3)


Basic Information

Item Value
gene id XLOC_026816
gene name nprl3
gene type coding
species zebrafish (Danio rerio)
category of species model fish

Chromosome Information

Item Value
chromosome id NC_007114.7
NCBI id CM002887.2
chromosome length 62628489
location 55045346 ~ 55079742 (-)
genome version GRCz11_2017_zebrafish_Genome

Sequence

>TCONS_00052147
AAACACTGTGCTGTTGTGTTTTAGAAAGAACCATAGAAAGAACTGACGTTTTGCTGTCAGTGCTATTTTTTCACTGTCAGATTGAGATCACAGTAAAATCAACATATTTAGCCAGCCGTTGACTGATGGATAAAACAATTTGGGCTACGATCTGGTAAATGATAACGTTGCGTGTGGTTATTTTGTTGCTGATTTTGGCTAACGTTAGCCAGCAGGCTAACAGAATTTGTTATTTATCAACCACTCATTTAGGTTATCAGTAATGCACTTCATCAAATGTACCGGGTTTCTCATACTCATAAACTCTAATGCAGATCAAACATTTAACCAACCACACCTAAGTTAACCAATCTTATCATATAAAGTCACAGTTTTAGCTTTAATTCCCTTGACATAACATAAGTATTTCACAAAAGGATGTACAAGCAGTGGACAGCAGATTTAAACTCAGACCCAAAGCCGATGTGGAAACAATCCGAGTCCAGCCTGCAGCCCAATGGGGAAAAAACAAGTCCCATCAGTGTGATATTAGTAAGTTCTGGCAGCCGAGGAAATAAACTGCTCTTCCGATACCCGTTCCAGAGAGCATCCGAAAACACGTCCTCTGCTACATcaAAACAGCGGAGTCCATATGTGTTGAATACCTCAGGCGACTCTACAGAGGACCAGGATGGTGATTCAAGGTTTTCGGATATTATTCTTGCCACCATCTTGGCCACCAAGTCTGATATGTGCGGCAAGAAGTTTGAACTAAAAATAGACAATGTGCGATTCGTTGGGCATCCAACCTTACTGCAGCCTCCTCATACTATTCAGGCTTCTAAAACGGACCCCTCCCCTAAAAGAGAGCTGCCCACCATGATTCTGTTcagtgttgtttttgcattacggGCGAATGCTGATGCGTCTGTGATCAGCTGTATGCACAATCTGTCCCGGCGGATCGCCATCGCTCTGCAGCATGAGGAGCGCAGGTGTCAGTACCTCACCAGGGAAGCCAAACTGATGTTGGTGATGCAGGACGAGGTCACCACCATTACTGACTCTGATGGCTCGCCACAGTCACCTTTTCGACAGATCCTTCCCAAGTGCAAGTTAGCAAGAGACCTGAAAGAGGCCTATGACAGCCTCTGCACAACTGGAGTTGTTCGGCTTCATATTAATAACTGGCTTGAGGTCAGTTTCTGCTTGCCACACAAAATCCACCGAGTAGGAGGAAAACACATCCCACTAGAGGCTCTCGAGCGCAGCCTAAAGGCCATTCGTCCGTATCATGCGCTGCTGCTGCTGGAAAATGAGAAGGTTTTGTTGGCTCAGCTACCTCTGGACTGCTCTCCTGCTTTAGTTCGCCTCATCAAGACCTGCTCGGCTGTCAAGAACCTGCAGCAGCTTGCACAGGATGCAGATCTCGCCCTCTTACAGATCTTCCAGATAGCAGCACATTTGGTGTACTGGGGTAAAGCCATCATTATTTACCCTCTCTGTGAGAACAACGTCTATATGCTCTCTCCTCATGCAAACATCTGCATCTACTCTCCTTTGGCTGAGCACTTTGCTGTCCAGTTTCCAGGTCATGATCTGCCCTCAATGCTGGCCAAATTCTCACTTCCTGTGTCTCTGTCTGAGTTCAGGAACCCTCTGGATGCCCCTGTGCATGAGGCTCATCTCATTCAGATGGTGGTGTGGATGCTCCAGCACAGACTGCTCTTTCAGCTCCACACATATGTGTGTCTGCTGGTGCCACCTAATGAGGAGGAGCCTGGACTGCGGGACGAGGAGCTGCCCATAGTCACTCGCGTTACAGGCCGGAGTCTGAGCACACCCAGCGCCCTGAGCTTCGGCTCTCCCACCAGTAGTGATGACATGACCCTGACCAGTCCCAGTATGGATAATTCCAGCGCTGAGCTGCAGACCGGCGGAGACTCTCCTCTCAATAAAAGAATGACAGAAACTCTTCTGGCCAGCCTGACTGAACACGAGCGGCAGGCCATCCTCAGAGTCCCCGCAGCGCAGAACCCAGAGGACCTTCGCCTGTTTGCCAGGCTGCTGCATTACTTCAGGGGCCATCATCACCTAGAGGAGATCATGTACAACGAGAACCTGCGCCGCTCACAGCTGAAGACTTTATTTGACAAGTTTCGCAGTGTGTTGGTGATCACCAACCACGAGGACCCCATCATCTCTCTGTTCCAGTCTCCACCAGAGTAAACCAACAGTAAAGTGAGTGTGAGGAGGCTGTCAACTGTCTGATCTTCATCGGTAGCTTAAACTAATTTTGAGCTGTGACCAGTTAATGAACATCTCAGCTTCATAAGAGCCTTATTAATGAGCCTTGCATAATCTACTGTCCATAACTCTTGTTTACCAAAGATTTTCCCTTTAATGTTTTTACCTCATACgtggtttattttaataaacgatCCAGGGGTCGTGATGTGCGGTTCATCCTTGGGCAGTCGTTAAATGGATGGTTTAAGTATCCCATCCAAGCATCTCCTGTTTGGAGCTCGTTCCCAAATGTGATAAATCATCTCTTCAAGCGAACAAGACTAAAAACACATGATGCCATGATGTTAATTCCAGACTGAATGCCCCGAGGAATTCAGTGTGGAGAAATGGAGgcccagaagaagaagaagaagaaaaaaggaggCTGTAATAGCCCTGAGGTGCAAATAGGTTTCCAAACATCTGCAAAATCAATGAGCACCAGGAATAACAGGACTATTTAACAAAGCAACATGCTCTTACTGAAATAACAGACATGTTCAGAGCTCAAACTCAATTATTTATGTCATACCAAACCTGTGTGACTTTGCTTTTAGTTATTTTGTACCTCAATACAGTAAAAAGACCACTGAGGACTTTCAAGATCCAATCACCCTGTCCATTCACCCAttcatttattgttaatttataattcttaaaaataattgttcaataaaagattaataatca
>TCONS_00052148
GGGGAAAAAACAAGTCCCATCAGTGTGATATTAGTAAGTTCTGGCAGCCGAGGAAATAAACTGCTCTTCCGATACCCGTTCCAGAGAGCATCCGAAAACACGTCCTCTGCTACATGTTTTCGGATATTATTCTTGCCACCATCTTGGCCACCAAGTCTGATATGTGCGGCAAGAAGTTTGAACTAAAAATAGACAATGTGCGATTCGTTGGGCATCCAACCTTACTGCAGCCTCCTCATACTATTCAGGCTTCTAAAACGGACCCCTCCCCTAAAAGAGAGCTGCCCACCATGATTCTGTTcagtgttgtttttgcattacggGCGAATGCTGATGCGTCTGTGATCAGCTGTATGCACAATCTGTCCCGGCGGATCGCCATCGCTCTGCAGCATGAGGAGCGCAGGTGTCAGTACCTCACCAGGGAAGCCAAACTGATGTTGGTGATGCAGGACGAGGTCACCACCATTACTGACTCTGATGGCTCGCCACAGTCACCTTTTCGACAGATCCTTC

Function

symbol description
nprl3 Predicted to be involved in several processes, including TORC1 signaling; cellular response to amino acid starvation; and negative regulation of TOR signaling. Predicted to be part of GATOR1 complex. Human ortholog(s) of this gene implicated in focal epilepsy. Orthologous to human NPRL3 (NPR3 like, GATOR1 complex subunit).

GO:

id name namespace
GO:0034198 cellular response to amino acid starvation biological_process
GO:2000785 regulation of autophagosome assembly biological_process
GO:0038202 TORC1 signaling biological_process
GO:0032007 negative regulation of TOR signaling biological_process
GO:1990130 GATOR1 complex cellular_component
GO:0003674 molecular_function molecular_function

KEGG:

id description
ko04150 mTOR signaling pathway
ko04131 Membrane trafficking

ZFIN:

id description
ZDB-GENE-030131-1348 Predicted to be involved in several processes, including TORC1 signaling; cellular response to amino acid starvation; and negative regulation of TOR signaling. Predicted to be part of GATOR1 complex. Human ortholog(s) of this gene implicated in focal epilepsy. Orthologous to human NPRL3 (NPR3 like, GATOR1 complex subunit).

Ensembl:

ensembl_id ENSDARG00000010918

RNA

RNA id representative length rna type GC content exon number start site end site
TCONS_00052147 False 2958 mRNA 0.46 13 55045346 55079742
TCONS_00052148 True 516 nonsense_mediated_decay 0.49 5 55063267 55079244

Neighbor

gene id symbol gene type direction distance location
XLOC_026815 rhbdf1a coding downstream 52319 54896331 ~ 54993027 (-)
XLOC_026814 NA coding downstream 161166 54873401 ~ 54884180 (-)
XLOC_026813 ubald1b coding downstream 198902 54833658 ~ 54846444 (-)
XLOC_026812 NA coding downstream 224446 54791553 ~ 54820900 (-)
XLOC_026811 NA coding downstream 261025 54748396 ~ 54784321 (-)
XLOC_026817 hbba2 coding upstream 11488 55091230 ~ 55092051 (-)
XLOC_026818 hbba1 coding upstream 18715 55098457 ~ 55099272 (-)
XLOC_026819 hbba1 coding upstream 23703 55103445 ~ 55104310 (-)
XLOC_026820 hbae1.1 coding upstream 40588 55120330 ~ 55121125 (-)
XLOC_026821 hbae1.3 coding upstream 47807 55127549 ~ 55128258 (-)
XLOC_026805 NA non-coding downstream 1202562 53842532 ~ 53842784 (-)
XLOC_026804 BX004869.1 non-coding downstream 1355918 53689310 ~ 53689428 (-)
XLOC_026831 NA non-coding upstream 758712 55838454 ~ 55839514 (-)
XLOC_026834 CU855917.1 non-coding upstream 1331399 56411141 ~ 56413023 (-)
XLOC_026840 NA non-coding upstream 1957352 57037094 ~ 57037670 (-)
XLOC_026851 CT583687.2 non-coding upstream 2977872 58057614 ~ 58059819 (-)
XLOC_026854 NA non-coding upstream 3028689 58108431 ~ 58110154 (-)

Expression


Co-expression Network