XLOC_026817 (hbba2)


Basic Information

Item Value
gene id XLOC_026817
gene name hbba2
gene type coding
species zebrafish (Danio rerio)
category of species model fish

Chromosome Information

Item Value
chromosome id NC_007114.7
NCBI id CM002887.2
chromosome length 62628489
location 55091230 ~ 55092051 (-)
genome version GRCz11_2017_zebrafish_Genome

Sequence

>TCONS_00052149
CAGATCCAAGTGTGAATTAGATACGCCATAATAACCAATCAGCGCCTCAGGGCGTAGAGTGCGAGTATAAATACACTCGCACGTAGCCTATCTTTGCTCAGCATTCGCTTGAAGAAAAATTGATAATCACGATGGTGCAGTGGTCAGATTCCGAGCGCAAAACAATTGCGAGTGTCTGGAGCAAAATCAACGTCGATGAAATCGGACCACAGACCTTGGCAAGGGTGCTGGTTGTTTATCCCTGGACTCAGAGGTATTTTGGCGCATTTGGAGATCTATCCTGTGCATCTGCAATCATGGGCAACCCCAAAGTTTCAGAACACGGCAAAACTGTGCTGAAAGCGTTGGAGAAAGCTGTCAAGAACGTGGATGACATCAAAACCACTTACGCCAAACTCAGCCAGCTGCACTGCGAGAAACTCAACGTCGATCCAGACAACTTCAAGCTGTTGGCGGACTGCCTGAGCATTGTCATCGCGACTAATTTTGGACCCGCTTTCAACCCCTCAGTCCAGTCAACCTGGCAGAAACTTTTGTCAGTAGTTGTGGCTGCTCTCACAAGCCGCTACTTCTGAACTCCTGTGCACGAGATCTCTGCCTCAATTCAATGATGATTCAATGCTTTAATCATTAATAAAGCAATCAATCAA

Function

symbol description
hbba2 Predicted to enable several functions, including heme binding activity; oxygen binding activity; and oxygen carrier activity. Predicted to contribute to haptoglobin binding activity and peroxidase activity. Predicted to be involved in hydrogen peroxide catabolic process. Predicted to act upstream of or within oxygen transport. Predicted to be part of haptoglobin-hemoglobin complex and hemoglobin complex. Is expressed in female organism and vasculature. Human ortholog(s) of this gene implicated in acute chest syndrome; hemolytic anemia (multiple); malaria; polycythemia (multiple); and sickle cell anemia. Orthologous to several human genes including HBE1 (hemoglobin subunit epsilon 1).

GO:

id name namespace
GO:0042744 hydrogen peroxide catabolic process biological_process
GO:0015671 oxygen transport biological_process
GO:0031838 haptoglobin-hemoglobin complex cellular_component
GO:0005833 hemoglobin complex cellular_component
GO:0019825 oxygen binding molecular_function
GO:0046872 metal ion binding molecular_function
GO:0004601 peroxidase activity molecular_function
GO:0043177 organic acid binding molecular_function
GO:0005344 oxygen carrier activity molecular_function
GO:0031720 haptoglobin binding molecular_function
GO:0020037 heme binding molecular_function

KEGG: NA

ZFIN:

id description
ZDB-GENE-040801-164 Predicted to enable several functions, including heme binding activity; oxygen binding activity; and oxygen carrier activity. Predicted to contribute to haptoglobin binding activity and peroxidase activity. Predicted to be involved in hydrogen peroxide catabolic process. Predicted to act upstream of or within oxygen transport. Predicted to be part of haptoglobin-hemoglobin complex and hemoglobin complex. Is expressed in female organism and vasculature. Human ortholog(s) of this gene implicated in acute chest syndrome; hemolytic anemia (multiple); malaria; polycythemia (multiple); and sickle cell anemia. Orthologous to several human genes including HBE1 (hemoglobin subunit epsilon 1).

Ensembl:

ensembl_id ENSDARG00000069734

RNA

RNA id representative length rna type GC content exon number start site end site
TCONS_00052149 True 650 mRNA 0.47 3 55091230 55092051

Neighbor

gene id symbol gene type direction distance location
XLOC_026816 nprl3 coding downstream 11488 55045346 ~ 55079742 (-)
XLOC_026815 rhbdf1a coding downstream 98203 54896331 ~ 54993027 (-)
XLOC_026814 NA coding downstream 207050 54873401 ~ 54884180 (-)
XLOC_026813 ubald1b coding downstream 244786 54833658 ~ 54846444 (-)
XLOC_026812 NA coding downstream 270330 54791553 ~ 54820900 (-)
XLOC_026818 hbba1 coding upstream 6406 55098457 ~ 55099272 (-)
XLOC_026819 hbba1 coding upstream 11394 55103445 ~ 55104310 (-)
XLOC_026820 hbae1.1 coding upstream 28279 55120330 ~ 55121125 (-)
XLOC_026821 hbae1.3 coding upstream 35498 55127549 ~ 55128258 (-)
XLOC_026822 hbae1.3 coding upstream 46362 55138413 ~ 55139127 (-)
XLOC_026811 NA non-coding downstream 306909 54748396 ~ 54784321 (-)
XLOC_026805 NA non-coding downstream 1248446 53842532 ~ 53842784 (-)
XLOC_026804 BX004869.1 non-coding downstream 1401802 53689310 ~ 53689428 (-)
XLOC_026831 NA non-coding upstream 746403 55838454 ~ 55839514 (-)
XLOC_026834 CU855917.1 non-coding upstream 1319090 56411141 ~ 56413023 (-)
XLOC_026840 NA non-coding upstream 1945043 57037094 ~ 57037670 (-)
XLOC_026851 CT583687.2 non-coding upstream 2965563 58057614 ~ 58059819 (-)
XLOC_026854 NA non-coding upstream 3016380 58108431 ~ 58110154 (-)

Expression


Co-expression Network

Homologous

species gene id symbol gene type chromosome NCBI id location
grasscarp (Ctenopharyngodon idella) CI01000113_00285871_00286497 NA coding CI01000113 null 285800 ~ 286543 (+)