XLOC_027012 (grm8a)



Basic Information


Item Value
gene id XLOC_027012
gene name grm8a
gene type coding
species zebrafish (Danio rerio)
category of species model fish

Chromosome Information


Item Value
chromosome id NC_007115.7
NCBI id CM002888.2
chromosome length 78093715
location 3478049 ~ 3745093 (+)
genome version GRCz11_2017_zebrafish_Genome

Sequence


>TCONS_00053281
acgcaagttggagctaaaatctgcaggacaccggacatCCAGAACCGAGTTTGAGAAGCAACTACAGTTGTCACTATATATGACTGTAGTACTTTATTTCGTGTGTCGTGGTcgttttattttttccaaaatgaCGACTGCGTGTGATGCACGGaagaggaaagagagagagagtgtgagtgaGAGAGCAATCACATTCACAGGGAGGATTTTGGTGATGCGCTGTTCATTTCAGCACCACAAACCACCATCAGAGAGCAGAAAGAAGATGCGTTTGAAGATGTGAGACGGTCGCAGCTCGGATGTTAAAAGGGACTTGTTTACTTCCTATCTAACACTTTTGAGAGTCTCCTTAAATCACCTGCTGCCGGTCACATGACGCACCACTGTGGCAACCTAAATGGCCGGGGTGCTTGGCTTCAGCTTTGAAACGGCCATGGATTTTCCTGTCCACCTACTTCCCCATTAGTCCCACCAATTGGAATCTGTATCCATTCGCTTCTTCAGATTTTCCCCAACAACTCTGTGGATATGGATCTTGTGTGCTTAAGCCGGACTCAATACCAGTTGCTTGTCTTTCTCTGCTACTGGTTTCCAGTCTCCCTCCAGAAGCTGGAGACGCCACCGATTGAGTATGCCCACTCTATCCGTCTGGATGGCGATATTATCCTGGGCGGCCTGTTTCCGGTTCATTCTCGGGGTGAGCGTGGGGTTCCTTGTGGAGAGTTAAAGAAGGAGAAAGGCATCCACCGATTAGAGGCAATGCTGTTTGCCATTGACCTCATCAATAAAGACCCAGATCTACTGCCCAATGTGACATTAGGTGCCCGAATTCTGGACACCTGCTCGCGGGACACTTACGCTCTGGAGCAGTCTCTTACCTTTGTGCAAGCTCTCATTGAGCGCGACGGTTCGGATGTACGCTGTGCCAATGGAGATCAGCCCATATTCGCCAAACCCGACAAAATTGTTGGCGTCATCGGTGCAGCTGCCAGCTCGGTCTCCATCAT
>TCONS_00053282
GGATATGGATCTTGTGTGCTTAAGCCGGACTCAATACCAGTTGCTTGTCTTTCTCTGCTACTGGTTTCCAGTCTCCCTCCAGAAGCTGGAGACGCCACCGATTGAGTATGCCCACTCTATCCGTCTGGATGGCGATATTATCCTGGGCGGCCTGTTTCCGGTTCATTCTCGGGGTGAGCGTGGGGTTCCTTGTGGAGAGTTAAAGAAGGAGAAAGGCATCCACCGATTAGAGGCAATGCTGTTTGCCATTGACCTCATCAATAAAGACCCAGATCTACTGCCCAATGTGACATTAGGTGCCCGAATTCTGGACACCTGCTCGCGGGACACTTACGCTCTGGAGCAGTCTCTTACCTTTGTGCAAGCTCTCATTGAGCGCGACGGTTCGGATGTACGCTGTGCCAATGGAGATCAGCCCATATTCGCCAAACCCGACAAAATTGTTGGCGTCATCGGTGCAGCTGCCAGCTCGGTCTCCATCATGGTCGCCAACATCTTGAGGCTTTTTAAGATTCCTCAGATCAGCTACGCATCCACCGCTCCGGAGCTCAGCGATAACACCCGCTACGACTTCTTTTCACGCGTCGTTCCACCGGATTCATACCAGGCGCAGGCCATGCTGGATATAGTGACGGCGATGGGCTGGAACTACGTCTCCACACTGGCTTCTGAAGGAAACTATGGGGAAAGTGGTGTGGAAGCGTTTGTGCAGATCTCCAGAGAAATGGgCGGTGTGTGTATCGCTCAGTCTCTGAAGATCCCGAGGGAACCGAGGGCTGGGGAATTTGACAAGATAATCCGGCGGCTCCTGGAGACCCCAAACGCTCGGGCCATCATCATGTTTGCCAATGAGGACGATATCAGGCGAGTGCTGGACTCCGCCAAGAGGAGCAACCAGACAGGTCACTTTCTGTGGGTGGGATCCGACAGCTGGGGCTCCAAAATCTCCCCTGTAATCCAGCAGGAGAGAGTGGCTGAAGGGGCCATCACCATCCTGCCCAAAAGAGCCACTGTAGATGCATTCGATCGTTATTTCCGCAGCCGCTCGCTGTCCAACAACAGAAGAAACGTGTGGTTTGCTGAGTTCTGGGAGGAAAACTTCGGCTGTAAACTCGGGATGCACGGCAAGAGGCCAGGAAGCCTGAAAAAGTGCACCGggcTGGAGAAAGTGGGCCGGGACTCTAGTTATGAGCAGGAAGGAAAGGTTCAGTTCGTGATGGATGCAGTGTATGCGATGGCTCACGCTCTCCACCGAATGCACAGGGAATACTGCTTCGGTTATCCCGGACTCTGCCCTCGCATGAGCAACATCAATGGGAAAGAGCTGCTGGGATATATACGCAACGTCAGCTTCAACGGAAGCGCAGGAACTCCAGTGGTCTTCAATCAGAACGGAGATGCACCAGGACGATACGACATCTTCCAATATCAGATCACCAACAAATCCACAGCTGAGTACAAAGTGATCGGCCAGTGGACAAACAAACTGCATCTAAACGTGAATGTGATGCGCTGGCGGACAGGCGACCCCAGACTTCCAGCTTCAGTGTGCAGTGTGCCATGTCAAATGGGTGAACGTAAGAAGATCGTGAAGGGTGTGCCCTGCTGCTGGCATTGTGAGCGGTGCGAAGGCTACCACTTCCAGGCCAGCGAGTTCAGCTGCGAACTCTGTCCTTATGAGCAGCGTCCAGACCGCAACCGCACCGGCTGCGTCCCCATCCCTATCATCAAACTGGAGTGGCATTCAGCTTGGGCAGCCGTGCCGGTGTTCGTTGCTGTTCTTGGCATTTTGGCCACCAGTTTTGTAGTGGTCACTTTTGTCCGTTACAATGATACCCCAATTGTCCGTGCATCTGGACGAGAGATGAGCTACGTCTTACTGACAGGTATTTTCTTATGTTACGCCATCACCTTCTTGATGATCGCCACCCCCAGTTTAGGCATCTGCTCCTTCAGGCGGGTGTTTCTTGGATTGGGCATGTGCTTCAGCTACGCGGCTCTACTAACCAAAACCAACCGTATCCATCGCATTTTTGAACAAGGAAAAAAGTCAGTGGCCGCTCCACGCTTTATCAGCCCTGCTTCCCAGCTGGTCATCACCTTCAGCCTGATCTCAGTTCAGTTGCtcggtgtgtttgtgtggtttgcTGTTGATCCTCCACATACAGTGGTGGACTATGGCGAGCAGCGCACGTCTGATCCAATGAAGGCCCGCGGGGTCCTAAAGTGCGACATCTCGGACCTGTCGCTCATCTGTTCTCTGGGCTACAGCATCCTTTTGATGGTCACATGCACTGTTTACGCCATCAAGACCCGTGGCGTGCCAGAAACTTTCAACGAGGCCAAGCCAATCGGATTTACTATGTACACTACCTGCATCATTTGGTTAGCTTTTATACCAATCTTCTTTGGCACTGCACAATCGGCGGAAAGGATGTACATCCAGACCACGACCCTCACCATCTCCCTCAGTctgagtgcgtctgtgtctctGGGGATGCTCTACATGCCCAAAGTCTACGTCATTATCTTCCACCCGGAGCAGAACGTTCCCAAACGCAAGCGCAGCTTTAAGGCCATTGTCACCGCCGCCACCATGTCTGGAAAACTGGTGCAGAAGGGCAGTGATCGACCCAATGGAGAGGTCAAGACTGAGCTGTGCGAGAGCATGGAGACCAACACAACATTTTCCACCAAGACGACGTATGTGAGCTACAGCAATCACGCCATATGAGGAGGGGCAGTCTCTGGGGGCGGAGTCGAGGGCGGGGCCTGTCACAAGCAGGATGTCTGCATTGTGACGCGCGCTGGCAGGAAAACGGACCTGGAATGGGCATCTGAGCATGAGATTTTTTATACCGTTCTGCATCAATCTAAAAAACCTGCAGCCTCCTGGGAGACGAACGGACATTGGTGGATcttccagagagactgctgaacaAGAGCTACCGACCCTGCCATGAACACACGT

Function


symbol description
grm8a Predicted to enable group III metabotropic glutamate receptor activity. Predicted to be involved in G protein-coupled glutamate receptor signaling pathway and regulation of glutamatergic synaptic transmission. Predicted to act upstream of or within G protein-coupled receptor signaling pathway. Predicted to be located in plasma membrane. Predicted to be integral component of membrane. Predicted to be integral component of plasma membrane. Is expressed in brain and retinal neural layer. Human ortholog(s) of this gene implicated in attention deficit hyperactivity disorder; autistic disorder; and schizophrenia. Orthologous to human GRM8 (glutamate metabotropic receptor 8).

GO:

id name namespace
GO:0051966 regulation of synaptic transmission, glutamatergic biological_process
GO:0007186 G protein-coupled receptor signaling pathway biological_process
GO:0007216 G protein-coupled glutamate receptor signaling pathway biological_process
GO:0007165 signal transduction biological_process
GO:0005886 plasma membrane cellular_component
GO:0005887 integral component of plasma membrane cellular_component
GO:0016020 membrane cellular_component
GO:0016021 integral component of membrane cellular_component
GO:0004930 G protein-coupled receptor activity molecular_function
GO:0001642 group III metabotropic glutamate receptor activity molecular_function
GO:0008066 glutamate receptor activity molecular_function

KEGG: NA

ZFIN:

id description
ZDB-GENE-110421-2 Predicted to enable group III metabotropic glutamate receptor activity. Predicted to be involved in G protein-coupled glutamate receptor signaling pathway and regulation of glutamatergic synaptic transmission. Predicted to act upstream of or within G protein-coupled receptor signaling pathway. Predicted to be located in plasma membrane. Predicted to be integral component of membrane. Predicted to be integral component of plasma membrane. Is expressed in brain and retinal neural layer. Human ortholog(s) of this gene implicated in attention deficit hyperactivity disorder; autistic disorder; and schizophrenia. Orthologous to human GRM8 (glutamate metabotropic receptor 8).

Ensembl:

ensembl_id ENSDARG00000077654

RNA


RNA id representative length rna type GC content exon number start site end site
TCONS_00053281 False 1010 mRNA 0.49 3 3478049 3482794
TCONS_00053282 True 2971 mRNA 0.53 10 3482312 3745093

Neighbor


gene id symbol gene type direction distance location
XLOC_027011 znf800b coding upstream 2652 3455146 ~ 3475397 (+)
XLOC_027010 atxn7l1 coding upstream 31291 3438510 ~ 3446758 (+)
XLOC_027009 NA coding upstream 55586 3421471 ~ 3422463 (+)
XLOC_027008 NA coding upstream 64894 3404869 ~ 3413155 (+)
XLOC_027007 sypl1 coding upstream 79664 3389866 ~ 3398385 (+)
XLOC_027014 NA coding downstream 68688 3813781 ~ 3815416 (+)
XLOC_027015 NA coding downstream 199623 3944716 ~ 3952419 (+)
XLOC_027016 gpr37b coding downstream 235154 3980247 ~ 3998490 (+)
XLOC_027017 NA coding downstream 314774 4059867 ~ 4063556 (+)
XLOC_027018 NA coding downstream 320225 4065318 ~ 4071401 (+)
XLOC_027005 NA non-coding upstream 139109 3309485 ~ 3338940 (+)
XLOC_027004 NA non-coding upstream 170195 3305178 ~ 3307854 (+)
XLOC_027002 NA non-coding upstream 574008 2902347 ~ 2904041 (+)
XLOC_027020 NA non-coding downstream 386997 4132090 ~ 4160221 (+)

Expression



Co-expression Network


Homologous


species gene id symbol gene type chromosome NCBI id location