Item | Value |
---|---|
gene id | XLOC_027048 |
gene name | apex1 |
gene type | coding |
species | zebrafish (Danio rerio) |
category of species | model fish |
Item | Value |
---|---|
chromosome id | NC_007115.7 |
NCBI id | CM002888.2 |
chromosome length | 78093715 |
location | 5333988 ~ 5340530 (+) |
genome version | GRCz11_2017_zebrafish_Genome |
symbol | description |
---|---|
apex1 | Predicted to enable DNA-(apurinic or apyrimidinic site) endonuclease activity; double-stranded DNA 3'-5' exodeoxyribonuclease activity; and phosphodiesterase I activity. Acts upstream of or within several processes, including heart contraction; heart looping; and negative regulation of apoptotic process. Predicted to be located in endoplasmic reticulum; mitochondrion; and nuclear lumen. Predicted to be active in nucleus. Is expressed in head. Human ortholog(s) of this gene implicated in breast cancer; female reproductive organ cancer (multiple); spina bifida; and urinary bladder cancer. Orthologous to human APEX1 (apurinic/apyrimidinic endodeoxyribonuclease 1). |
id | name | namespace |
---|---|---|
GO:0010628 | positive regulation of gene expression | biological_process |
GO:0080111 | DNA demethylation | biological_process |
GO:0006974 | cellular response to DNA damage stimulus | biological_process |
GO:0043066 | negative regulation of apoptotic process | biological_process |
GO:0001947 | heart looping | biological_process |
GO:0060047 | heart contraction | biological_process |
GO:0006281 | DNA repair | biological_process |
GO:0006284 | base-excision repair | biological_process |
GO:0005783 | endoplasmic reticulum | cellular_component |
GO:0005634 | nucleus | cellular_component |
GO:0016607 | nuclear speck | cellular_component |
GO:0005730 | nucleolus | cellular_component |
GO:0005737 | cytoplasm | cellular_component |
GO:0005739 | mitochondrion | cellular_component |
GO:0003906 | DNA-(apurinic or apyrimidinic site) endonuclease activity | molecular_function |
GO:0004518 | nuclease activity | molecular_function |
GO:0004519 | endonuclease activity | molecular_function |
GO:0046872 | metal ion binding | molecular_function |
GO:0004528 | phosphodiesterase I activity | molecular_function |
GO:0016787 | hydrolase activity | molecular_function |
GO:0003677 | DNA binding | molecular_function |
GO:0016829 | lyase activity | molecular_function |
GO:0140078 | class I DNA-(apurinic or apyrimidinic site) endonuclease activity | molecular_function |
GO:0003723 | RNA binding | molecular_function |
GO:0008311 | double-stranded DNA 3'-5' exodeoxyribonuclease activity | molecular_function |
id | description |
---|---|
ZDB-GENE-040426-2761 | Predicted to enable DNA-(apurinic or apyrimidinic site) endonuclease activity; double-stranded DNA 3'-5' exodeoxyribonuclease activity; and phosphodiesterase I activity. Acts upstream of or within several processes, including heart contraction; heart looping; and negative regulation of apoptotic process. Predicted to be located in endoplasmic reticulum; mitochondrion; and nuclear lumen. Predicted to be active in nucleus. Is expressed in head. Human ortholog(s) of this gene implicated in breast cancer; female reproductive organ cancer (multiple); spina bifida; and urinary bladder cancer. Orthologous to human APEX1 (apurinic/apyrimidinic endodeoxyribonuclease 1). |
ensembl_id | ENSDARG00000045843 |
RNA id | representative | length | rna type | GC content | exon number | start site | end site |
---|---|---|---|---|---|---|---|
TCONS_00053318 | False | 2136 | mRNA | 0.44 | 6 | 5333988 | 5339829 |
TCONS_00053317 | False | 2139 | mRNA | 0.44 | 6 | 5333988 | 5339829 |
TCONS_00053319 | False | 2119 | mRNA | 0.44 | 5 | 5333988 | 5339857 |
TCONS_00053320 | False | 709 | mRNA | 0.52 | 5 | 5334008 | 5338470 |
TCONS_00053321 | False | 388 | mRNA | 0.47 | 4 | 5334031 | 5334815 |
TCONS_00053322 | False | 579 | mRNA | 0.49 | 5 | 5334035 | 5337992 |
TCONS_00053323 | False | 754 | mRNA | 0.51 | 5 | 5334202 | 5338466 |
TCONS_00053324 | False | 2690 | mRNA | 0.42 | 4 | 5334439 | 5340530 |
TCONS_00053325 | True | 682 | mRNA | 0.48 | 2 | 5334707 | 5338373 |
gene id | symbol | gene type | direction | distance | location |
---|---|---|---|---|---|
XLOC_027047 | si:ch211-214j24.10 | coding | upstream | 8652 | 5317483 ~ 5325336 (+) |
XLOC_027046 | NA | coding | upstream | 29316 | 5302949 ~ 5304672 (+) |
XLOC_027045 | ccdc167 | coding | upstream | 60150 | 5255041 ~ 5273838 (+) |
XLOC_027044 | si:ch211-214j24.14 | coding | upstream | 80015 | 5249494 ~ 5253973 (+) |
XLOC_027043 | galnt8b.2 | coding | upstream | 110818 | 5215950 ~ 5223170 (+) |
XLOC_027049 | zgc:113263 | coding | downstream | 1062 | 5341592 ~ 5368158 (+) |
XLOC_027050 | selenoo2 | coding | downstream | 37808 | 5378338 ~ 5387478 (+) |
XLOC_027051 | si:dkey-14d8.20 | coding | downstream | 51564 | 5392094 ~ 5494298 (+) |
XLOC_027052 | BX324164.1 | coding | downstream | 80376 | 5420906 ~ 5456058 (+) |
XLOC_027053 | NA | coding | downstream | 84330 | 5424860 ~ 5456948 (+) |
XLOC_027036 | NA | non-coding | upstream | 367438 | 4963839 ~ 4966550 (+) |
XLOC_027035 | NA | non-coding | upstream | 371366 | 4938766 ~ 4962622 (+) |
XLOC_027034 | NA | non-coding | upstream | 407927 | 4832804 ~ 4926061 (+) |
XLOC_027032 | NA | non-coding | upstream | 618827 | 4711163 ~ 4715161 (+) |
XLOC_027054 | NA | non-coding | downstream | 105239 | 5445769 ~ 5447230 (+) |
XLOC_027063 | CU571169.1 | non-coding | downstream | 484838 | 5825368 ~ 5826340 (+) |
XLOC_027069 | NA | non-coding | downstream | 616873 | 5957403 ~ 5963871 (+) |