XLOC_027103 (wnt5b)


Basic Information

Item Value
gene id XLOC_027103
gene name wnt5b
gene type coding
species zebrafish (Danio rerio)
category of species model fish

Chromosome Information

Item Value
chromosome id NC_007115.7
NCBI id CM002888.2
chromosome length 78093715
location 8532580 ~ 8663117 (+)
genome version GRCz11_2017_zebrafish_Genome

Sequence

>TCONS_00053422
TGACGCCGTCATACACTGAAGCGCGGTACGTTTATCAAAACTTTCAACCGTTTTCACCGAGTGACTTTCGCGGAGCCTTTTTTATTCTCACTATGGACAGCGCCGGACTGTTTTGGAGTATGTCTTTGGTTTTCTAAGTGAATGAAACACTGGAAACTCTAGTGCCAAGTTAAATTGTTCGGAGGTGGAATTGTCTAATATTTTCTGAAGTTACTCCTACTTTGTATGCGCTTCACAAGAACATCACGCAGAGCCAGAAGACCAGGTTCAGCTGTCAGGACTTCAGCTCTGGAACTTTTTTGGAGACGGATAGATCGACATCTGCTAACAAGTGTGCAAAGCCATCTTTCCCTGAAGTCTTTCCTATTGACGGACAAGCTGTTCAACCAATAAAGCACAGGTTTTTGCTCGGGATACATCTTTCTTCCATTTCGACAATCAACTTTGATCCAACTTCCAAGAACTTCCATCTGAGGAGGCGCTTTGCATTTCAATTTCTTGGAGGAGGAAGGATGGATGTGAGAATGAACCAAGGACACCTACTTCTGGCAGTGACCCTCATCGTCTGCAACTCACAGCTGCTGGTGGTCGCCAACTCGTGGTGGTCATTAGCCATGAACCCCATCCAGAGACCGGAGATGTACATCATTGGAGCACAGCCTCTGTGCAGCCAGCTGACGGGCCTATCTCAGGGTCAGAGGAAGCTCTGCCAGCTCTATCAGGACCACATGGTTTATATTGGAGAGGGGGCGAAGACGGGCATCAAAGAGTGCCAGTATCAGTTCAGACAGAGGCGATGGAACTGCAGTACAGTGGACAACACGTCAGTGTTCGGCCGTGTCATGCATATAGGCAGCCGAGAAACAGCTTTTACATACGCCGTCAGCGCAGCGGGTGTTGTGAATGCTGTGAGTCGAGCGTGCCGTGAGGGTGAGCTTTCCACCTGCGGCTGCAGTCGAGCGGCTCGTCCCAGAGACCTGCCCAGAGACTGGCTGTGGGGCGGCTGCGGGGACAACGTCAACTATGGCTACCGCTTCGCCCGGGAGTTTGTGGACGCTCGTGAACGTGAGAAGAACTACCCACGCGGATCGGTGGAACACGCACGCACGCTTATGAATCTGCAGAACAATGAAGCCGGAAGAATGGCGGTGTATAATCTAGCGAATGTGGCCTGCAAGTGTCATGGCGTCTCAGGCTCGTGCAGCTTGAAAACCTGCTGGCTCCAGCTGGCCGACTTCCGGCGTGTTGGAGAATTCCTGAAGGAGAAATACGACAGCGCCGCCGCCATGCGCATTAACCGACGTGGAAAACTAGAGCTGGTCAATAATCGATTCAACCCACCGACAGGTGAAGATCTGGTCTACATCGACCCCAGCCCGGATTACTGCCTGCGCAATGAAACCACTGGGTCTCTGGGCACCCAAGGCCGCCTATGCAACAAGACCTCGGAGGGTATGGACGGCTGCGAGCTCATGTGCTGCGGCCGCGGGTACGACCAGTTCAAGACCTACAAACATGAGCGCTGCCACTGCAAGTTCCACTGGTGCTGCTATGTCAAGTGCAAACGCTGCACGTCACTCGTAGACCAGTTTGTGTGCAAGTAGCAGACGTGAGAACTGGGGGACAGACGCACTGAGCAATTAAGCAGGAGAAGAAACGGGACCCTTAACGGACCCAGAGGGGCAACTTAgagataattaaatgtaaaaatgatatattaaatagcaacaaattaaaataagtatataaataagtGTACGTGTGCCGTTGATAGTAATTTAATGACCTGAGGATCCACGTTGGACGTCATTGATGAAAAAGGAGGCACCGGTGTGATGCATTCCGGCTCAAGCTGTGTTTCTCTCATAAAGAGAGGAAGGAACTCTTGACTTGTGCTACAAGAAACTCTTTAGAGACTCGAGGAAAAGGCGCAGAAATAGGATGGGGAACATCAAGGGCGCATCACCCACCCATTGCCTTCcaattcataaacacacacacacactccaccttGCTGATGTCAGAGCTCTTAAGAACTTTCGGAATGCG
>TCONS_00053423
CCTTTCAGGTGTGCAAAGCCATCTTTCCCTGAAGTCTTTCCTATTGACGGACAAGCTGTTCAACCAATAAAGCACAGGTTTTTGCTCGGGATACATCTTTCTTCCATTTCGACAATCAACTTTGATCCAACTTCCAAGAACTTCCATCTGAGGAGGCGCTTTGCATTTCAATTTCTTGGAGGAGGAAGGATGGATGTGAGAATGAACCAAGGACACCTACTTCTGGCAGTGACCCTCATCGTCTGCAACTCACAGCTGCTGGTGGTCGCCAACTCGTGGTGGTCATTAGCCATGAACCCCATCCAGAGACCGGAGATGTACATCATTGGAGCACAGCCTCTGTGCAGCCAGCTGACGGGCCTATCTCAGGGTCAGAGGAAGCTCTGCCAGCTCTATCAGGACCACATGGTTTATATTGGAGAGGGGGCGAAGACGGGCATCAAAGAGTGCCAGTATCAGTTCAGACAGAGGCGATGGAACTGCAGTACAGTGGACAACACGTCAGTGTTCGGCCGTGTCATGCATATAGGCAGCCGAGAAACAGCTTTTACATACGCCGTCAGCGCAGCGGGTGTTGTGAATGCTGTGAGTCGAGCGTGCCGTGAGGGTGAGCTTTCCACCTGCGGCTGCAGTCGAGCGGCTCGTCCCAGAGACCTGCCCAGAGACTGGCTGTGGGGCGGCTGCGGGGACAACGTCAACTATGGCTACCGCTTCGCCCGGGAGTTTGTGGACGCTCGTGAACGTGAGAAGAACTACCCACGCGGATCGGTGGAACACGCACGCACGCTTATGAATCTGCAGAACAATGAAGCCGGAAGAATGGCGGTGTATAATCTAGCGAATGTGGCCTGCAAGTGTCATGGCGTCTCAGGCTCGTGCAGCTTGAAAACCTGCTGGCTCCAGCTGGCCGACTTCCGGCGTGTTGGAGAATTCCTGAAGGAGAAATACGACAGCGCCGCCGCCATGCGCATTAACCGACGTGGAAAACTAGAGCTGGTCAATAATCGATTCAACCCACCGACAGGTGAAGATCTGGTCTACATCGACCCCAGCCCGGATTACTGCCTGCGCAATGAAACCACTGGGTCTCTGGGCACCCAAGGCCGCCTATGCAACAAGACCTCGGAGGGTATGGACGGCTGCGAGCTCATGTGCTGCGGCCGCGGGTACGACCAGTTCAAGACCTACAAACATGAGCGCTGCCACTGCAAGTTCCACTGGTGCTGCTATGTCAAGTGCAAACGCTGCACGTCACTCGTAGACCAGTTTGTGTGCAAGTAGCAGACGTGAGAACTGGGGGACAGACGCACTGAGCAATTAAGCAGGAGAAGAAACGGGACCCTTAACGGACCCAGAGGGGCAACTTAgagataattaaatgtaaaaatgatatattaaatagcaacaaattaaaataagtatataaataagtGTACGTGTGCCGTTGATAGTAATTTAATGACCTGAGGATCCACGTTGGACGTCATTGATGAAAAAGGAGGCACCGGTGTGATGCATTCCGGCTCAAGCTGTGTTTCTCTCATAAAGAGAGGAAGGAACTCTTGACTTGTGCTACAAGAAACTCTTTAGAGACTCGAGGAAAAGGCGCAGAAATAGGATGGGGAACATCAAGGGCGCATCACCCACCCATTGCCTTCcaattcataaacacacacacacactccaccttGCTGATGTCAGAGCTCTTAAGAACTTTCGGAATGCG
>TCONS_00053424
TTCCCCAGAGGAGGCGCTTTGCATTTCAATTTCTTGGAGGAGGAAGGATGGATGTGAGAATGAACCAAGGACACCTACTTCTGGCAGTGACCCTCATCGTCTGCAACTCACAGCTGCTGGTGGTCGCCAACTCGTGGTGGTCATTAGCCATGAACCCCATCCAGAGACCGGAGATGTACATCATTGGAGCACAGCCTCTGTGCAGCCAGCTGACGGGCCTATCTCAGGGTCAGAGGAAGCTCTGCCAGCTCTATCAGGACCACATGGTTTATATTGGAGAGGGGGCGAAGACGGGCATCAAAGAGTGCCAGTATCAGTTCAGACAGAGGCGATGGAACTGCAGTACAGTGGACAACACGTCAGTGTTCGGCCGTGTCATGCATATAGGCAGCCGAGAAACAGCTTTTACATACGCCGTCAGCGCAGCGGGTGTTGTGAATGCTGTGAGTCGAGCGTGCCGTGAGGGTGAGCTTTCCACCTGCGGCTGCAGTCGAGCGGCTCGTCCCAGAGACCTGCCCAGAGACTGGCTGTGGGGCGGCTGCGGGGACAACGTCAACTATGGCTACCGCTTCGCCCGGGAGTTTGTGGACGCTCGTGAACGTGAGAAGAACTACCCACGCGGATCGGTGGAACACGCACGCACGCTTATGAATCTGCAGAACAATGAAGCCGGAAGAATGGCGGTGTATAATCTAGCGAATGTGGCCTGCAAGTGTCATGGCGTCTCAGGCTCGTGCAGCTTGAAAACCTGCTGGCTCCAGCTGGCCGACTTCCGGCGTGTTGGAGAATTCCTGAAGGAGAAATACGACAGCGCCGCCGCCATGCGCATTAACCGACGTGGAAAACTAGAGCTGGTCAATAATCGATTCAACCCACCGACAGGTGAAGATCTGGTCTACATCGACCCCAGCCCGGATTACTGCCTGCGCAATGAAACCACTGGGTCTCTGGGCACCCAAGGCCGCCTATGCAACAAGACCTCGGAGGGTATGGACGGCTGCGAGCTCATGTGCTGCGGCCGCGGGTACGACCAGTTCAAGACCTACAAACATGAGCGCTGCCACTGCAAGTTCCACTGGTGCTGCTATGTCAAGTGCAAACGCTGCACGTCACTCGTAGACCAGTTTGTGTGCAAGTAGCAGACGTGAGAACTGGGGGACAGACGCACTGAGCAATTAAGCAGGAGAAGAAACGGGACCCTTAACGGACCCAGAGGGGCAACTTAgagataattaaatgtaaaaatgatatattaaatagcaacaaattaaaataagtatataaataagtGTACGTGTGCCGTTGATAGTAATTTAATGACCTGAGGATCCACGTTGGACGTCATTGATGAAAAAGGAGGCACCGG

Function

symbol description
wnt5b Enables signaling receptor binding activity. Involved in muscle cell differentiation; positive regulation of convergent extension involved in gastrulation; and positive regulation of non-canonical Wnt signaling pathway. Acts upstream of or within with a positive effect on midbrain-hindbrain boundary morphogenesis. Acts upstream of or within several processes, including animal organ development; convergent extension; and vasculature development. Predicted to be located in extracellular region. Predicted to be active in extracellular space. Is expressed in several structures, including central nervous system; cranial cartilage; fin; germ ring; and mesoderm. Human ortholog(s) of this gene implicated in autosomal dominant Robinow syndrome 1. Orthologous to several human genes including WNT5B (Wnt family member 5B).

GO:

id name namespace
GO:0060070 canonical Wnt signaling pathway biological_process
GO:0042074 cell migration involved in gastrulation biological_process
GO:0009826 unidimensional cell growth biological_process
GO:0021555 midbrain-hindbrain boundary morphogenesis biological_process
GO:0007223 Wnt signaling pathway, calcium modulating pathway biological_process
GO:0036342 post-anal tail morphogenesis biological_process
GO:0002574 thrombocyte differentiation biological_process
GO:0031018 endocrine pancreas development biological_process
GO:0030182 neuron differentiation biological_process
GO:0001501 skeletal system development biological_process
GO:0001503 ossification biological_process
GO:0045165 cell fate commitment biological_process
GO:0051209 release of sequestered calcium ion into cytosol biological_process
GO:0002062 chondrocyte differentiation biological_process
GO:0007275 multicellular organism development biological_process
GO:0001525 angiogenesis biological_process
GO:0010172 embryonic body morphogenesis biological_process
GO:0048840 otolith development biological_process
GO:0048884 neuromast development biological_process
GO:0031101 fin regeneration biological_process
GO:0008591 regulation of Wnt signaling pathway, calcium modulating pathway biological_process
GO:0061053 somite development biological_process
GO:0060536 cartilage morphogenesis biological_process
GO:0060026 convergent extension biological_process
GO:0060027 convergent extension involved in gastrulation biological_process
GO:0060028 convergent extension involved in axis elongation biological_process
GO:0060030 dorsal convergence biological_process
GO:0001667 ameboidal-type cell migration biological_process
GO:0048701 embryonic cranial skeleton morphogenesis biological_process
GO:0001946 lymphangiogenesis biological_process
GO:0048703 embryonic viscerocranium morphogenesis biological_process
GO:0001958 endochondral ossification biological_process
GO:0016055 Wnt signaling pathway biological_process
GO:0005576 extracellular region cellular_component
GO:0005615 extracellular space cellular_component
GO:0005102 signaling receptor binding molecular_function
GO:0005109 frizzled binding molecular_function
GO:0005125 cytokine activity molecular_function

KEGG: NA

ZFIN:

id description
ZDB-GENE-980526-87 Enables signaling receptor binding activity. Involved in muscle cell differentiation; positive regulation of convergent extension involved in gastrulation; and positive regulation of non-canonical Wnt signaling pathway. Acts upstream of or within with a positive effect on midbrain-hindbrain boundary morphogenesis. Acts upstream of or within several processes, including animal organ development; convergent extension; and vasculature development. Predicted to be located in extracellular region. Predicted to be active in extracellular space. Is expressed in several structures, including central nervous system; cranial cartilage; fin; germ ring; and mesoderm. Human ortholog(s) of this gene implicated in autosomal dominant Robinow syndrome 1. Orthologous to several human genes including WNT5B (Wnt family member 5B).

Ensembl:

ensembl_id ENSDARG00000102464

RNA

RNA id representative length rna type GC content exon number start site end site
TCONS_00053422 False 2049 mRNA 0.51 7 8532580 8663117
TCONS_00053423 False 1726 mRNA 0.52 6 8569199 8663117
TCONS_00053424 True 1366 mRNA 0.54 4 8638622 8662899

Neighbor

gene id symbol gene type direction distance location
XLOC_027101 ERC1 coding upstream 16756 8213063 ~ 8515824 (+)
XLOC_027102 BX649324.3 coding upstream 28779 8503687 ~ 8503801 (+)
XLOC_027100 ninj2 coding upstream 323926 8168514 ~ 8208654 (+)
XLOC_027099 CU695020.2 coding upstream 397870 8134594 ~ 8134710 (+)
XLOC_027098 NA coding upstream 483322 8045442 ~ 8049258 (+)
XLOC_027104 adipor2 coding downstream 7545 8670662 ~ 8737886 (+)
XLOC_027105 NA coding downstream 53008 8716125 ~ 8726451 (+)
XLOC_027106 sult4a1 coding downstream 134080 8797197 ~ 8810740 (+)
XLOC_027107 NA coding downstream 211448 8874565 ~ 8885723 (+)
XLOC_027108 samm50l coding downstream 348331 9011448 ~ 9025993 (+)
XLOC_027090 NA non-coding upstream 814921 7715601 ~ 7717659 (+)
XLOC_027088 NA non-coding upstream 865834 7652574 ~ 7666746 (+)
XLOC_027111 NA non-coding downstream 444142 9107259 ~ 9148954 (+)
XLOC_027113 NA non-coding downstream 534233 9197350 ~ 9203068 (+)
XLOC_027115 NA non-coding downstream 677710 9340827 ~ 9346703 (+)

Expression


Co-expression Network

Homologous

species gene id symbol gene type chromosome NCBI id location
grasscarp (Ctenopharyngodon idella) CI01000066_00620105_00632826 WNT5B coding CI01000066 null 620105 ~ 632826 (+)