XLOC_027252 (spx)



Basic Information


Item Value
gene id XLOC_027252
gene name spx
gene type coding
species zebrafish (Danio rerio)
category of species model fish

Chromosome Information


Item Value
chromosome id NC_007115.7
NCBI id CM002888.2
chromosome length 78093715
location 16794418 ~ 16797485 (+)
genome version GRCz11_2017_zebrafish_Genome

Sequence


>TCONS_00053664
ATGAAAGATTTAAGGACTCTTGCGGCGTACGCACTTGCGCTGTTACTTCTTGCAACATTTGTGTCCCATTCCTGGAGCGCACCCAAGggCAGTTTTCAGCGTCGGAATTGGACACCCCAAGCTATGTTATATCTGAAAGGCACACAGGGACGGCGCTTTGTGTCAGAAGACAGAAATGAAGGGGACCTGTATGATACAATACGCTTAGAATCCCGCAGTCAAAACACAGAAAACCTGAGCATCTCTAAAGCAGCGGCGTTTCTCCTGAACATCCTCCAGCAGGCCAGAGATGAAGACGAGCCGTACTGA
>TCONS_00053665
GACACCCCAAGCTATGTTATATCTGAAAGGCACACAGGGACGGCGCTTTGTGTCAGAAGACAGAAATGAAGGGGACCTGTATGATACAATACGCTTAGAATCCCGCAGTCAAAACACAGAAAACCTGAGCATCTCTAAAGCAGCGGCGTTTCTCCTGAACATCCTCCAGCAGGCCAGAGATGAAGACGAGCCGTACTGAAGAACATCAGCTCAACACCGCCAGCTTTCAGCTTCTCTAATGTGCcgttatttgtgtttgtttcattCCACCGGGACTGATTATTTAAGGAATACAGCAGAGACTGATAGGGAGGTATTTCTCGCTTCCTATGGATTCATTTCAGCTGATATAATGAGTTGTTTTTATTCAAGACGTATCAACTTGGAAAAGAGATTATTTACGGCGAGTGCGATTCTGTGTAATATAAATGAACTGTACAGTTTCTGTTTTTCTTCCTTTTGAGTTTCTCATGTTAAAAAATCGACACTTGATGCTctgtaaaatacatatttgagAATGTCTGAACATTTTCTCTATCAATTAAACTAAATTTGCACTGA

Function


symbol description
spx Predicted to enable neuropeptide hormone activity; type 2 galanin receptor binding activity; and type 3 galanin receptor binding activity. Involved in cholesterol homeostasis; glucose homeostasis; and triglyceride homeostasis. Acts upstream of or within negative regulation of eating behavior. Located in nucleus. Is expressed in several structures, including central nervous system; heart; liver; male organism; and pleuroperitoneal region. Orthologous to human SPX (spexin hormone).

GO:

id name namespace
GO:0003084 positive regulation of systemic arterial blood pressure biological_process
GO:0035814 negative regulation of renal sodium excretion biological_process
GO:0032099 negative regulation of appetite biological_process
GO:1903999 negative regulation of eating behavior biological_process
GO:0070328 triglyceride homeostasis biological_process
GO:1904306 positive regulation of gastro-intestinal system smooth muscle contraction biological_process
GO:0010459 negative regulation of heart rate biological_process
GO:0044539 long-chain fatty acid import into cell biological_process
GO:0042593 glucose homeostasis biological_process
GO:0042632 cholesterol homeostasis biological_process
GO:0045944 positive regulation of transcription by RNA polymerase II biological_process
GO:0051930 regulation of sensory perception of pain biological_process
GO:0030133 transport vesicle cellular_component
GO:0031045 dense core granule cellular_component
GO:0005576 extracellular region cellular_component
GO:0005615 extracellular space cellular_component
GO:0005634 nucleus cellular_component
GO:0031410 cytoplasmic vesicle cellular_component
GO:0031765 type 2 galanin receptor binding molecular_function
GO:0031766 type 3 galanin receptor binding molecular_function
GO:0005179 hormone activity molecular_function
GO:0005184 neuropeptide hormone activity molecular_function

KEGG: NA

ZFIN:

id description
ZDB-GENE-041210-158 Predicted to enable neuropeptide hormone activity; type 2 galanin receptor binding activity; and type 3 galanin receptor binding activity. Involved in cholesterol homeostasis; glucose homeostasis; and triglyceride homeostasis. Acts upstream of or within negative regulation of eating behavior. Located in nucleus. Is expressed in several structures, including central nervous system; heart; liver; male organism; and pleuroperitoneal region. Orthologous to human SPX (spexin hormone).

Ensembl:

ensembl_id ENSDARG00000056859

RNA


RNA id representative length rna type GC content exon number start site end site
TCONS_00053664 False 309 mRNA 0.50 5 16794418 16797123
TCONS_00053665 True 561 mRNA 0.40 3 16795688 16797485

Neighbor


gene id symbol gene type direction distance location
XLOC_027251 golt1ba coding upstream 2222 16787040 ~ 16792196 (+)
XLOC_027250 STMP1 coding upstream 8174 16784553 ~ 16786244 (+)
XLOC_027249 BX649476.1 coding upstream 12576 16777715 ~ 16781842 (+)
XLOC_027248 BX649500.1 coding upstream 21164 16768961 ~ 16773254 (+)
XLOC_027246 NA coding upstream 36382 16750256 ~ 16758036 (+)
XLOC_027253 kiss2 coding downstream 29905 16827390 ~ 16828499 (+)
XLOC_027254 NA coding downstream 42068 16839553 ~ 16844705 (+)
XLOC_027255 etnk1 coding downstream 88369 16885854 ~ 16906923 (+)
XLOC_027256 NA coding downstream 166818 16964303 ~ 16966927 (+)
XLOC_027257 NA coding downstream 183934 16981419 ~ 16985283 (+)
XLOC_027247 NA non-coding upstream 41122 16752361 ~ 16753296 (+)
XLOC_027243 NA non-coding upstream 255456 16535258 ~ 16538962 (+)
XLOC_027242 NA non-coding upstream 419726 16374269 ~ 16374692 (+)
XLOC_027239 NA non-coding upstream 480519 16309076 ~ 16313899 (+)
XLOC_027258 CR792413.1 non-coding downstream 264495 17061980 ~ 17062097 (+)
XLOC_027259 NA non-coding downstream 293211 17090696 ~ 17095120 (+)

Expression



Co-expression Network