XLOC_028367 (ptpro)


Basic Information

Item Value
gene id XLOC_028367
gene name ptpro
gene type coding
species zebrafish (Danio rerio)
category of species model fish

Chromosome Information

Item Value
chromosome id NC_007115.7
NCBI id CM002888.2
chromosome length 78093715
location 190547 ~ 211714 (-)
genome version GRCz11_2017_zebrafish_Genome

Sequence

>TCONS_00055101
ATGAGTTCCGCTCGTGCGCGcttcttcttcatcatcttcatcttcattcaGagTGCCGCTGGGTTCCGTGTGCAGCTCCAGGATGGCGTGCGGATGCTGATGTCTCTGGATGATGGTGACATTGGGCCGGGTGTGTCTGAGTACGCGGTGCGAGTGTCCGGAGagccgctcacacacacactgctgttccAGCAAGCGGCCGACGCGCACACACTCCCCGAACCGCTGCTGTTTAACGCCTCGTACCACGGCCTGCTGTACTCCATCAGCCTGATGACCGACGGCAGAACACACACCACCCGCAGCATCATCACACagCCGCTTCCTCTAGACAGTGTGGAGATGTGGGACTATGCGCCGTCTCCAGAGACCGCTGTGGTGTTTCAGATTCGCTCTCCAGACAGAAACATCTTCACCAGAGTCAACATCAGCTACACGGAGGGACACCAGCGCAGATACATGCTCTataaagatTTCCTCCATGGTAAAACCGTGTTCAAGCACTGGTTGTCAGGTGTGTGTTACAGCAACATCACCTTCCAGCTGATCTCTGAAGCTTCAGTCAACAGGAGCGCTCTGCTGAGCCGCAGCGACATTACCCATAATCCTCAGCAGCATCGCACcgTCCCGAACCCTCCTCTGAACGTGTCCCTGAAGATCCTTCATCTGAGCGGGCGTGGGCCGCCGGGACCCGTCCTAACCGGAGCCATTCTGAAGAATTCCCACAATGCATCCGTGGTGCGGCGGGAGCGTGACCTGCCAGAGTATGAAGAGCAGGAGCCGACCAGCGACACACTCAACACCGAGAGCAACCTCACACACACTCAACTGAACCAGTCTGAATCAGAAAATGAATCTGAATCTGAACCAGTCACAGCTGAACCCACACTGAACAGCAGCACACAGAGTCTGTGGGCGTGGCAGACAGTAAGCCCCGCCCCcacagaggaggaggaggaggggttTGTGAATGCGCTGGTGCCAGAATACGAGGACTCGAATGAACCCGGGTCAGCGCTGGGCATCCCCCTGGAGCCCGCTGTGATGCCTGCTGTGATGCCCACGCCGCTGGCACCTGTCCTGCTGCAGCTGCGCTGGTCTCCGCCAGCACCGCACACTGCTTACGACGCCTTCAACATCTACATCTACCGCAATGGAAACTCCACAGAAACTGCGACGGTTGATGAAAACACACATGAGTTCTTGGCGGAACTCTCCGAATCGGGAACATATCGCATTCACGTCACAACACTGAGCTCTGCTGGAGACTGCGAAGCCCGAGAGAGTTCAGCCAACACCGCATTCACCTTCTAcctcagtcCGTCCGGTGAGTGGATGGAGCAACCACAGGAGCGTCCGCAGGCCGTGAGTGTGAAGATGTTGGACTCCAGCACAGCTGCAGTGTCCTGGGCTccgtccacacacacatacaatggcAGTCTGATCTCGGTGCAGTCGCTCACGTGTCTGCGGCCCAGCATCAGCCAGCGCATGGAGCTCAACTACTGCTCCGAGGAGAACATCACCAGTGACATCATCAGCAGCCTGACCCCCGGCGCCCAGTACCGCGTGGTGGTTTACCACACTAATGGGCCGCTGGTCAGCCCCGCGTCTGAACCAGTCATCATCGATATAGaGCCGACAGGTGTGCGTGATCTGGTCGTGTATCCTCTGAGTCCCAGCGCCGTCATCCTGAGCTGGCAGAGGCCGTATAATGTGGCTTTCCGGAAATACGTCCTGCAGACCTTCTTCTTCAACTCGGCCACGCAGACGGCGCAATGGAGCACGTACTACGAGATCGCCGCCACCGCATCTGTCATCGCCTCTGTgaGAGTGACAGATCTGCTGCCCGCCTGGTTTTACAATTTCCGTGTGACGATGGTGACATGGGGCGATCCTCCGCTCAGCTGCTGCGACACCTCCACTGTCAGCTTCAtcacagcTCCCGAAGCGCCGCACATCTCCTCAGTGGAGTTCTCTCATGGATCAGTGTTTGTGCGCTGGACGTACGGAGATTTGTTCACGGATCTCACACACTCGCGCATGCTGCACTGGCAGGTGGTGGCGGAGGGCAAGAAGAGCGCCAGGAGACGATTCTCCGTAGACgtaaCCCGCAGTGTGATGAAGGCGTCTCTGGCCCTCCCAGCGGGTGACATCTATAACCTGACGGTGACGGCCTGCACCGAGCGCAGCTGCAACACATCTGCACCACACATCATGAAGCTGGACCCGGCTCCTCCGCGCTCTCTGTACGCGGTGAACGCTAGCGACACATCCGTCACGCTAATCTGGGCGGAGGAGGGCGTGGTGGACCACTACCTGATCACCTGCAGAGCCCTGGGAGCCCACGCAGAGCAGAAGaagGTGCGTGAGCCATTGGTGACCTCGGCTCATGTTCTGACCGTGTCGGGTCTGCAGGCGTCCACAACCTACAACTGCAGTGTGAGGAGCAGCAGCTACAGCAGCTCCAGTGACCCAGTGCACATCACCGTCAGCACTacagttttttttctcatcattattattattattattattagattttttatattattattattattattatcattattatttttatttatttttattatt

Function

symbol description
ptpro Predicted to enable protein tyrosine phosphatase activity. Acts upstream of or within cerebellum morphogenesis and regulation of fibroblast growth factor receptor signaling pathway. Predicted to be located in membrane. Predicted to be integral component of membrane. Is expressed in several structures, including brain; eye; optic cup; optic vesicle; and tail bud. Human ortholog(s) of this gene implicated in nephrotic syndrome type 6. Orthologous to human PTPRO (protein tyrosine phosphatase receptor type O).

GO:

id name namespace
GO:0021587 cerebellum morphogenesis biological_process
GO:0006470 protein dephosphorylation biological_process
GO:0040036 regulation of fibroblast growth factor receptor signaling pathway biological_process
GO:0007417 central nervous system development biological_process
GO:0016311 dephosphorylation biological_process
GO:0016020 membrane cellular_component
GO:0016021 integral component of membrane cellular_component
GO:0016787 hydrolase activity molecular_function
GO:0016791 phosphatase activity molecular_function
GO:0004721 phosphoprotein phosphatase activity molecular_function
GO:0004725 protein tyrosine phosphatase activity molecular_function

KEGG:

id description
ko01009 Protein phosphatases and associated proteins

ZFIN:

id description
ZDB-GENE-070424-54 Predicted to enable protein tyrosine phosphatase activity. Acts upstream of or within cerebellum morphogenesis and regulation of fibroblast growth factor receptor signaling pathway. Predicted to be located in membrane. Predicted to be integral component of membrane. Is expressed in several structures, including brain; eye; optic cup; optic vesicle; and tail bud. Human ortholog(s) of this gene implicated in nephrotic syndrome type 6. Orthologous to human PTPRO (protein tyrosine phosphatase receptor type O).

Ensembl:

ensembl_id ENSDARG00000100422

RNA

RNA id representative length rna type GC content exon number start site end site
TCONS_00055101 True 2598 mRNA 0.56 15 190547 211714

Neighbor

gene id symbol gene type direction distance location
XLOC_028365 eps8a coding downstream 12037 151506 ~ 178510 (-)
XLOC_028364 tbk1 coding downstream 41213 134412 ~ 149334 (-)
XLOC_028363 gpr19 coding downstream 57055 128697 ~ 133492 (-)
XLOC_028361 dusp16 coding downstream 70858 107287 ~ 119689 (-)
XLOC_028368 RERG coding upstream 22098 233812 ~ 240737 (-)
XLOC_028369 si:ch73-252i11.1 coding upstream 57729 269443 ~ 277081 (-)
XLOC_028370 echdc3 coding upstream 74711 286425 ~ 287425 (-)
XLOC_028371 mrps10 coding upstream 113314 325028 ~ 330748 (-)
XLOC_028372 dynlt1 coding upstream 174721 386435 ~ 390442 (-)
XLOC_028362 NA non-coding downstream 71353 116322 ~ 119194 (-)
XLOC_028360 NA non-coding downstream 89170 99991 ~ 101377 (-)
XLOC_028359 NA non-coding downstream 115939 73430 ~ 74608 (-)
XLOC_028358 NA non-coding downstream 117889 71463 ~ 72658 (-)
XLOC_028357 NA non-coding downstream 125844 56025 ~ 64703 (-)
XLOC_028373 NA non-coding upstream 181837 393551 ~ 396819 (-)
XLOC_028375 CU855889.2 non-coding upstream 489898 701612 ~ 734347 (-)
XLOC_028376 NA non-coding upstream 512116 723830 ~ 732484 (-)
XLOC_028383 NA non-coding upstream 688248 899962 ~ 904022 (-)
XLOC_028385 NA non-coding upstream 708038 919752 ~ 921761 (-)

Expression


Co-expression Network

Homologous

species gene id symbol gene type chromosome NCBI id location
grasscarp (Ctenopharyngodon idella) CI01000068_01028235_01048221 PTPRO coding CI01000068 null 1028235 ~ 1049678 (+)