XLOC_028403 (ube2nb)



Basic Information


Item Value
gene id XLOC_028403
gene name ube2nb
gene type coding
species zebrafish (Danio rerio)
category of species model fish

Chromosome Information


Item Value
chromosome id NC_007115.7
NCBI id CM002888.2
chromosome length 78093715
location 1809562 ~ 1818315 (-)
genome version GRCz11_2017_zebrafish_Genome

Sequence


>TCONS_00055150
CGGATGATGACGGTTTTTTACCGGAAGACTCACGCGCATGCGCTGTCAACCTCAACGCGAGGAGCAGGGAGCGGGCCACGGTGCAAACCGCATTAATAAAACGAGATGGCTGGATTGCCGCGCAGGATTATTAAGGAGACGCAGCGCTTGTTAGCCGAGCCTGTGCCAGGAATCAAAGCGGAGCCAGATGAGGGGAACGCTCGTTATTTCCATGTGGTCATCGCTGGTCCGCAGGATTCACCATTTGAGGGCGGGACTTTCAAACTGGAGCTGTTCCTCCCAGAGGAGTATCCCATGGCGGCTCCAAAGGTCCGATTTATGACCAAAATCTACCATCCCAATGTGGACAAACTGGGCAGGATCTGTCTGGACATCCTGAAAGATAAATGGTCTCCTGCACTCCAGATTCGTACGGTGCTGCTGTCTATCCAGGCTCTATTAAGCGCTCCAAACCCTGACGATCCACTGGCCAATGATGTAGCCGAACAGTGGAAGAGCAACGAGGCTCAGGCCATCGAGACAGcCCGAACATGGACCAGGCTTTATGCCGGCAACAACATTGAAGTTTAGAAAGAAGAAAAGGTGGCGCCAAGTGAGAGAAGTGGAACAATCTCCTCCTGTCTTCTTTTGCATTTAAAGGACACTTTCTCAGACAAAATAAAAAACGTAAACGATAAAATAATACATGATTCAAAAGCATCTACTGCAGCCTATCGGGTGAGTGTTGGTGTGCTCCTGGTTCAGAGCTGATGTTTGCTCCACTATATGCTTTAACCAGGATAATGACGTGTGGTGATGGCCTGGGGGATTTCCCAGCATCCCTTGCGTGGTCACTACACTGGACCCTGTCAGAATGTGTAGTACAGTCCCTATTACAGTCATTAACGCAGTGAATTTCACTGGAAACAGGTTGTAGGCTCCAGGTgtaatggtttgtttgttttttttatgttattgggCGTAGAGGGAGGGCAGGTTAAACGCGGGTTGCATTTATGCTGCTTCTTGGTCAGGGACAAAATgatgtgaattattattattattattattattattaacttttttttttactttttctttcctGTGAAACTCTTCAGTTGATTAAAAGCATGTCTAAATTATGTCCTATCTGACAGAACCTGCTCTGACGTCGTTGTATTGCAAAcaaaacttgtgtgtgtgtgtgtgtgtggtttgtgtttCGGCTGGCGTGGAATCTGTACGAATCGTCTGGGAAAATTGAATCTGTAAATGTTCAGttttagtaaaaatattttttgttatgtta

Function


symbol description
ube2nb Predicted to enable ubiquitin binding activity and ubiquitin conjugating enzyme activity. Acts upstream of or within DNA damage response, detection of DNA damage. Predicted to be part of UBC13-MMS2 complex. Predicted to be active in nucleus. Orthologous to several human genes including UBE2N (ubiquitin conjugating enzyme E2 N).

GO:

id name namespace
GO:0006301 postreplication repair biological_process
GO:0045739 positive regulation of DNA repair biological_process
GO:0051443 positive regulation of ubiquitin-protein transferase activity biological_process
GO:0070534 protein K63-linked ubiquitination biological_process
GO:0033182 regulation of histone ubiquitination biological_process
GO:0042769 DNA damage response, detection of DNA damage biological_process
GO:0031058 positive regulation of histone modification biological_process
GO:0043123 positive regulation of I-kappaB kinase/NF-kappaB signaling biological_process
GO:0016574 histone ubiquitination biological_process
GO:0000209 protein polyubiquitination biological_process
GO:0000724 double-strand break repair via homologous recombination biological_process
GO:0000729 DNA double-strand break processing biological_process
GO:0051092 positive regulation of NF-kappaB transcription factor activity biological_process
GO:0050852 T cell receptor signaling pathway biological_process
GO:0031372 UBC13-MMS2 complex cellular_component
GO:0005634 nucleus cellular_component
GO:0016740 transferase activity molecular_function
GO:0005524 ATP binding molecular_function
GO:0000166 nucleotide binding molecular_function
GO:0043130 ubiquitin binding molecular_function
GO:0061631 ubiquitin conjugating enzyme activity molecular_function

KEGG: NA

ZFIN:

id description
ZDB-GENE-040426-1291 Predicted to enable ubiquitin binding activity and ubiquitin conjugating enzyme activity. Acts upstream of or within DNA damage response, detection of DNA damage. Predicted to be part of UBC13-MMS2 complex. Predicted to be active in nucleus. Orthologous to several human genes including UBE2N (ubiquitin conjugating enzyme E2 N).

Ensembl:

ensembl_id ENSDARG00000045877

RNA


RNA id representative length rna type GC content exon number start site end site
TCONS_00055150 True 1288 mRNA 0.45 4 1809562 1818315

Neighbor


gene id symbol gene type direction distance location
XLOC_028402 nudt4b coding downstream 7943 1788748 ~ 1801619 (-)
XLOC_028401 dnajc2 coding downstream 24442 1766333 ~ 1785120 (-)
XLOC_028400 tm7sf3 coding downstream 52102 1732825 ~ 1757460 (-)
XLOC_028399 gas2l3 coding downstream 88914 1689312 ~ 1720648 (-)
XLOC_028398 arid2 coding downstream 125215 1647098 ~ 1684347 (-)
XLOC_028404 mrpl42 coding upstream 3322 1821637 ~ 1824836 (-)
XLOC_028405 pwp1 coding upstream 7524 1825839 ~ 1839352 (-)
XLOC_028406 NA coding upstream 30345 1848660 ~ 1855771 (-)
XLOC_028407 ano6 coding upstream 60258 1878573 ~ 1914228 (-)
XLOC_028408 NA coding upstream 97471 1915786 ~ 1979057 (-)
XLOC_028393 NA non-coding downstream 549821 1054661 ~ 1259741 (-)
XLOC_028394 NA non-coding downstream 575326 1223164 ~ 1234236 (-)
XLOC_028392 NA non-coding downstream 773516 1028836 ~ 1036046 (-)
XLOC_028391 NA non-coding downstream 785862 1022316 ~ 1023700 (-)
XLOC_028389 NA non-coding downstream 796467 1010960 ~ 1013095 (-)
XLOC_028417 NA non-coding upstream 573757 2392072 ~ 2440175 (-)
XLOC_028418 NA non-coding upstream 627442 2445757 ~ 2479720 (-)
XLOC_028422 NA non-coding upstream 845853 2664168 ~ 2666870 (-)

Expression



Co-expression Network


Homologous


species gene id symbol gene type chromosome NCBI id location
grasscarp (Ctenopharyngodon idella) CI01000066_03686086_03690640 UBE2NA, UBE2NB, UBE2N coding CI01000066 null 3685931 ~ 3691102 (+)
tiger barb (Puntius tetrazona) G49252 ube2n,ube2nb,ube2na non-coding NC_056705.1 CM032074.1 2063552 ~ 2066093 (+)