XLOC_028429 (pik3cg)


Basic Information

Item Value
gene id XLOC_028429
gene name pik3cg
gene type coding
species zebrafish (Danio rerio)
category of species model fish

Chromosome Information

Item Value
chromosome id NC_007115.7
NCBI id CM002888.2
chromosome length 78093715
location 3343171 ~ 3353595 (-)
genome version GRCz11_2017_zebrafish_Genome

Sequence

>TCONS_00055198
GGGAACGCGCTTTCTGGGTGATCgcgtttattttgtattaataacAACGGCTGAAATAACAGAGTTTATACTTATTCGTAGTCTGTATTGGCTCTCACTGCATCCATGTATCAGTATTTACTCGACCGCGTTCAGGGTCATTGGCTCTGCATTTGCTGAACGCATTGGTTATGGAACAGCAAGCCAGTGATGATGAACCACCAGTAGTTCGCAGAGAGGAAAACAAGAGGAGAAGGAGAAGGATGAAAGCATTTACATCTGCCTCGGCTGTCTCGATGGAACATATAGCTGTTGAGTTTGTACTTCCTACCAccaataaaaatagcaaaacttTAGACACATTGCAACTAGACGTGACTGGAAATTGGACGGTAGAGCAGGTGAAGGTTCAGCTTTGGCACAGAGCGGTAACCTCTAAGTTATGCCCTGAATTTTACCAAAAATACTCTCCAGACTACTGCATCCTGCTTTATCAGAAGAAAGGCAACTGGTATGAAATCTATGACAAACAGCAGGTATTCCAAACCCTTGACTGCATTAGATATTGGAAAGCGTTGAGGAAAGATGTAGGGAAAATCCATCTGGTTGTTCGGCAACAACCTGCTGAGGATTCGCTTCAGTACCAACGATTTCTCAACCATCTAATTGGATATGATGTCACCGATGTCAGCAACGTCCATGACGATGAACTGGAGTTTACACGAAGAAAGCTACTGACCCCTCGGAAAATTGAGCTATCTGATCGGGATCCCAACCTTTATTCGATGGATCCCTGGATGACCACAACACCAATGCCTGAATACTTGCTCAGCAAAATAAGCAACAATCATATCCTGATGGTGATACACAAAGAGACAACAAGCCAGACTATTAAGGTGTCTATAGATGATACACCAGTCCAGGTACTTCAAAGCTTCTTCGCCAAGATTACTAACAAGCGAGCACTTTTAGGCATATCTGAAGACGTCAGTGAATCAGATTTTGTCTTAAGGGTTTGCGGAAGAGAGGAATACCTATATGGCAACAACGCAATTAAAGATTTCCACTGGATCAGACAGTGTCTTAAAAACGGTGAAGAGATTCATCTAGTTTTAGAGCACCCCCCAAACCCAGAACAAGATGTGGTTCAAAAAGAGGACTGGTCTCAGGTTGATGACTGCACTGGTGTCGCTGGTACTCACGAACAACTAACCATAACTGAGAAAGACCATGAAAAGGTGTTCACCATCTCCCTTTGGGACTGCAATCGTAAATTCAGGGTGAAGATCTTGGGTATTGACATTCCAGTACTCCCGCGTAATTCAGAATTGATCGTGTTTGTGGAGGCCAGTATTTTCCATGGACAACAACTGCTGGCTCAAGAAAGGACAAGCTCAAAACCATTCACAGAAGAGGTGATTTGGAACACCTGGTTGGAGTTTAATATAAAGATCAAGGACTTACCCAAAGGTGCCCGACTTAGCCTGCAAGTGTCGTGTGGAAAGGCACAGACACAAACATCAAAGGAAACTGAATGTAAAAACAAGTCTCGCTTACTCTACTATGTCAACCTGTTATTAGTTGATCACCGCTCCCTACTTAGACAAGGTGAGTTCATCTTGCACATGTGGAAGATGCCTGAGAAGAGTGAAGACAACAGCAGTGTAAATGCAGATAAGCTTACATCCGCAACCAACCCAGACAAGAACAACTCAATGGCTGTTGCTATTCTCCTGGACAAGTACTGCTACCCTGTGGCTCTTCCCAAGAGCAAAGATTCTCCTGATATTGAAGGCGAAAGAGGGCAGAGAGAGATGCCCAACCATCTACGCAAACAATTTGAGCAGATTATTGCTACAGACCCTTTGCACCCGCTCACCTCCGAAGATAAAGAGTTGCTCTGGCACTTCCGGCAGGAGTGCATGAGGGATCCGAAAGCATATCCGAAGTTTCTTTCCTCCGTTAAGTGGGGCAAACAAGAGGCTGTGGCCATAACGCATTATCTTCTGGAAAGGAGCACCATATGGGACCGAAGCGTGCTTGATGTGGGTTTGGTCTTACAATTACTGGACTGCCACTTCTCTGATGAAAACGTGCGCACTATAGCTGTCCGGAAGTTGGAGACTTTGGGAGATGATGATGTCCTGCGGTATCTTCTGCAACTTGTCCAGGCTGTAAAATTTGAACCATACCATGACAGCGCACTTGCAAGGTTCCTTCTGAAACGTGCACTCAGAAGCAAGCGGATCGGCCATTTCTTGTTCTGGTTTTTAAGAAGTGAAATTGCCCAATCCATGCACTATCAGCAGAGGTATGCTGTAATACTGGAAGCGTATCTCCGTGGCTGTGGTGAAGAAATGCTACAGGACTTCAGGAAGCAGGTGGAGATCACAGAGGCCTTGCAAAAGGTCGCTCGTGAGATTAAGCAAATATCTGCTGAGAAGTATGACATATCAGCACAAGTTGTTTTTCAGCTGCGCCAGAAACTGGAAGGTCTGCAAGTCTTAGGGTTGCCAGACAGCTTTAAAGTGCCTTACGATCCGGGCCTACGAGCAGGGGCACTTGTGATTGAGCAATGCAAAGTTATGGCATCCAAGAAGAAACCCTTGTGGCTGCAGTTCAAACGAGCCGATCCCACCACTTTGTCGAGCGACACAATTGGGATAATCTTTAAAGATGGGGATGACCTTCGTCAGGACATGCTGATATTACAGATTCTACTTATTATGGAGTCTATCTGGGAGCTGGAGTCATTAGATCTTTCCTTGTTACCTTACGGCTGCATTTCCACTGGAAATAAAATTGGAATGATTGAAATAGTGAAGGATGCCACTACCATTGCAAACATTCAGCAAAGCACTGTTGGGAACACCGGAGCTTTTAAAGATGAAATCCTCAGCCAGTGGCTTCGAGAAAAGTGTGTCAATGAGGACAAGCATCAACAGGCTGTAGATCGCTTTGTGTTCTCGTGTGGAGGGTATTGTGTGGCGACTTATGTCCTTGGCATTGGTGATCGTCACAATGACAACATAATGATCACTGAGACAgGTAATCTCTTCCACATTGATTTCGGACACATACTTGGCAACTACAAGAGTTTCTTGGGAATAAGCAAGGAGCGAGTTCCCTTTGTGCTGACTCCAGATTTCCTCTACCTGATGGGCACAACAGGAAAGAAAAGCAGCCCTAATTTCCTCCAGTTTCAGAATGTCTGTCTGAAGGCCTACCTGGCGCTGAGACACCACACCAACCTGCTGATCATCCTGTTCTCCATGATGCTGATGACCGGGATGCCTCAACTCACCAGCAAAGAGGACATAGAGTACATTCGGGAGGCGCTGACAGTAGGACGCTCAGAGGACGAGGCCAAACAGCACTTCTTGGACCAAATTGAGATCTGTCGGGACAAGGGTTGGACGGTGCAGTTTAACTGGTTCCTACATTTGGTGCTCGGCATTAAACAGGGTGTGGAGAAACGGTCAGCTTGAAGACCGACCAAAGGAAATCTGCATCTGTTTTGAAAAGAtctgctgtgtttttattttgccaggtatatttattgacattttgagCAGATGCAAAAATAGGTAACGCActgttctgctttttttttttaactaatgacCAAAAAACTATGTAGTTATTAAATAACGcagtaaatgtaaaatctaaaaagtaaaaataataataataaaaagcctttattcctCTTGTGCTTCAAGATTAATAGCATCAATATAATTCAACCAATGTTTACATGTTTTGTACACATATTTTTAAGATTTTcttaatgaaaacttttttttttcagttttaaatgcaaaaaatatatatatatatatattttatgcatcTATGACCTgcagtttttttatattacaaagtttttttaatgtaattttatagttgtattattatttaatgcatttacatcACGCATTGCATTGGTTTTAAATGCACAATTGCATTATTTCCTATTGCAGGCTTGATATTATCTTGCATATTCATGAAATATAGATTTCTTGCTTGTTTTATGAGATTGGATCATGTGAAATGTCTGTAAATATAGCAGATTTGTGGAGAAAAGTTGATGTTCTGATAGTCATGTGATCTTTTTacaaagttattaaaataaatgtcaattttagACATAGATTAAaacataatgttttatatttatctttaaatttaatactgataataattaGGCAGAGTATTTGTCTGGTCATCTAATTTCAACAGAGCAACCCTGTAATATATTTGATGTAATAAAGAATCCTTGTTATTTTCTATAGACACAttttttataaagcaaaaagCTCTTAATGGCACCaagtattttgtttttgatttatttattttattttttgtagtgtcCTGGTTgaaactttacatttaaattaattttaacataaaattaattgcgttttaaattaataaattgacaTGTTTTAGTCTCCCTTGATTAATTTATTCAGTAACTAAAAGTGTTCAGTAATGATACAGGTCTAGTAGAGGTCATGTGACATGATCACCGATATgaagaataatttaaatatacatataagaAGAATCAGTGAAACTGCTGATTACAATTATATAAATTGgacatatttaatataatgtcTAACCCACTAAATGTGAGTACTGACGTGAGATTGCTTTCATCATGTATGGATTACCAATATAGTACACGTTTCCATTTCactattgtactttttttttaaatgtgtattgctttctttatataataaatttctattaaaatgatttacaaAAAATA

Function

symbol description
pik3cg Predicted to enable 1-phosphatidylinositol-3-kinase activity and 1-phosphatidylinositol-4-phosphate 3-kinase activity. Acts upstream of or within neutrophil chemotaxis. Predicted to be part of phosphatidylinositol 3-kinase complex, class IA and phosphatidylinositol 3-kinase complex, class IB. Predicted to be active in cytoplasm and plasma membrane. Human ortholog(s) of this gene implicated in autistic disorder and swine influenza. Orthologous to human PIK3CG (phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma).

GO:

id name namespace
GO:0046854 phosphatidylinositol phosphorylation biological_process
GO:0016477 cell migration biological_process
GO:0036092 phosphatidylinositol-3-phosphate biosynthetic process biological_process
GO:0048015 phosphatidylinositol-mediated signaling biological_process
GO:0030593 neutrophil chemotaxis biological_process
GO:0014065 phosphatidylinositol 3-kinase signaling biological_process
GO:0016310 phosphorylation biological_process
GO:0005886 plasma membrane cellular_component
GO:0005942 phosphatidylinositol 3-kinase complex cellular_component
GO:0005943 phosphatidylinositol 3-kinase complex, class IA cellular_component
GO:0005944 phosphatidylinositol 3-kinase complex, class IB cellular_component
GO:0016020 membrane cellular_component
GO:0005737 cytoplasm cellular_component
GO:0016740 transferase activity molecular_function
GO:0035005 1-phosphatidylinositol-4-phosphate 3-kinase activity molecular_function
GO:0005524 ATP binding molecular_function
GO:0052742 phosphatidylinositol kinase activity molecular_function
GO:0000166 nucleotide binding molecular_function
GO:0016301 kinase activity molecular_function
GO:0016303 1-phosphatidylinositol-3-kinase activity molecular_function

KEGG:

id description
ko00562 Inositol phosphate metabolism
ko04371 Apelin signaling pathway
ko04072 Phospholipase D signaling pathway
ko04022 cGMP-PKG signaling pathway
ko04151 PI3K-Akt signaling pathway
ko04611 Platelet activation
ko04062 Chemokine signaling pathway
ko04921 Oxytocin signaling pathway
ko04261 Adrenergic signaling in cardiomyocytes
ko04725 Cholinergic synapse
ko05167 Kaposi sarcoma-associated herpesvirus infection
ko05132 Salmonella infection
ko05145 Toxoplasmosis
ko04131 Membrane trafficking

ZFIN:

id description
ZDB-GENE-040426-2532 Predicted to enable 1-phosphatidylinositol-3-kinase activity and 1-phosphatidylinositol-4-phosphate 3-kinase activity. Acts upstream of or within neutrophil chemotaxis. Predicted to be part of phosphatidylinositol 3-kinase complex, class IA and phosphatidylinositol 3-kinase complex, class IB. Predicted to be active in cytoplasm and plasma membrane. Human ortholog(s) of this gene implicated in autistic disorder and swine influenza. Orthologous to human PIK3CG (phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma).

Ensembl:

ensembl_id ENSDARG00000017757

RNA

RNA id representative length rna type GC content exon number start site end site
TCONS_00055198 True 4762 mRNA 0.40 11 3343171 3353595

Neighbor

gene id symbol gene type direction distance location
XLOC_028428 NA coding downstream 34756 3306145 ~ 3308415 (-)
XLOC_028427 NA coding downstream 85607 3250774 ~ 3257564 (-)
XLOC_028426 plekha5 coding downstream 197812 2948063 ~ 3145359 (-)
XLOC_028425 aebp2 coding downstream 397865 2923199 ~ 2945306 (-)
XLOC_028424 pde3a coding downstream 475059 2752852 ~ 2868112 (-)
XLOC_028430 NA coding upstream 38626 3392221 ~ 3405250 (-)
XLOC_028431 NA coding upstream 54116 3407711 ~ 3415152 (-)
XLOC_028432 CU928073.1 coding upstream 92416 3446011 ~ 3456102 (-)
XLOC_028433 si:dkey-61f9.1 coding upstream 439355 3792950 ~ 3805992 (-)
XLOC_028434 si:dkey-61f9.1 coding upstream 452663 3806258 ~ 3811017 (-)
XLOC_028422 NA non-coding downstream 676301 2664168 ~ 2666870 (-)
XLOC_028418 NA non-coding downstream 863451 2445757 ~ 2479720 (-)
XLOC_028417 NA non-coding downstream 902996 2392072 ~ 2440175 (-)
XLOC_028435 NA non-coding upstream 460023 3813618 ~ 3819984 (-)
XLOC_028436 NA non-coding upstream 467263 3820858 ~ 3821848 (-)

Expression


Co-expression Network

Homologous

species gene id symbol gene type chromosome NCBI id location
grasscarp (Ctenopharyngodon idella) CI01000066_03158972_03165320 PIK3CG coding CI01000066 null 3158316 ~ 3165320 (-)