XLOC_028466 (ada2b)


Basic Information

Item Value
gene id XLOC_028466
gene name ada2b
gene type coding
species zebrafish (Danio rerio)
category of species model fish

Chromosome Information

Item Value
chromosome id NC_007115.7
NCBI id CM002888.2
chromosome length 78093715
location 5225552 ~ 5247335 (-)
genome version GRCz11_2017_zebrafish_Genome

Sequence

>TCONS_00055248
AGATCTCGTCTCGTTGTGTTGTTATTGACTGGCTGGTTTGGATAATAGCGTCCCACTGGCAAGGCATTGCTCAAGGCTCTTATTCTATGAGGCATTTAAGATTTCACAGTGTGTCACATGCTCTATTGTCATCACATTCTTAATATGCGCTGTTCCTGAAAGAGGAACTTTTATTCGACATGCACAGCGGCTGAGAACACATGCCTGATTGATAGCTGGGAGCAATGAGTAGCATAAGCTTGAAGGATGTGAGTGCAGCAGTCATGGTGGTGCTGCTGGTGTGTGTGAGCGAGTGTAAATCAATGCCAGATCCCCGTCAGAGAGAGCAGATGCTGCAGCAGGAGCTCTTACAGCAGATCGGGGGAAACATGGAGCTCAATGAAGCCGAAAAGCGGATGGATTCACTGCTGTACATGCTGAAGATGAAGGAAATCACCCTTTCACCTTTCCCACCGGCCAATCACTTCTTCAAAGTGCGGCACATCATACAGCAAAGCCCGATATTCAAACTGCTGCAGAAAATGCCAAAAGGTGCTGCCCTTCACATCCATAACTCTGCTATGGTGAGTGTTGATTGGCTGCTGAACGCCACATACAGGCCTAACTGCTACATCTGCTTCACTTGGGACGGATCGGTTCGGTTCATGTTCTCCACCAGTACACCCTTTCCGCGCTGGGGATGCTCTTTTTGGAAACGGCTAGACATTTTAAGAGCCAGTCTTGGTGATGTCACTTCCTTTGATAACAGCTTGATGCGTAATCTAACGCTTTTTACGGAAGACCCGGAGACGTCTTATCCCACACAGGACTATATATGGAAGCGGTTTGAGAAGATTTTCATTGCTCTGTCTGGGCTGATCACATATGCTCCTGTCCTGAAGGATCACATCTACCAGGGTTTGAAAGAGCTTTATGAAGACAACATCATGTATGTGGAGCTGAGGATTGGACAGGCCAAGGCATATGAACTGGACGGCACTACCCATGACAGAGCGTGGACTATCGAGGTCTACAGAAACATCACTGAGCAGTTCAGAGCAAATCATCCAGACTTTATAGGAACTCGTGTAATCCTCTCCGCTCACAGGTCTTCTAGTGTGTCTCGAGTGAAGCAGGCTGTGCAGGAGGCCATTGAGATgcagagaaaatatccagagatTGTTGCAGGATTTGACCTGGTTGGTCGTGAAGACACCGGAGGGTCAATCTGGTATTTTCGGGATGCTTTATCACTCCCTTCAGAGTCACAACTTCCGTACTTTTTCCACGCTGGAGAAACAGATTTGGATGGGACCGATGTGGACAGGAATGTGTTAGACGCTCTGCTGTTTAACACCAGCCGTATCGGACACGGTTTTGCAATTGTTCATCATCCCGTAGCAAAACAGCTCTCCAGGAGCAGGAGGGTGGCAGTGGAGTTGTGTCCCATTTCCAATCAGGTGCTAAAGCTGGTCTCAGATCTGCGAAATCATCCAGCCGCGGTGTTAATGTCTGACGGACATCCTATGGTGGTCAGCTCCGATGATCCCAGTTTATTCGGGACCACAGGACTGTCCTATGATTTCTATGAGGTGTTTGTCGGTATTGGTGGATTGAGTGCAAACCTGGGCACTCTAAAGGAGCTCGCTATCAACTCAATCAGGTACAGTTCATTATCAGCACAACTGCAGGATAAAGCTATGACCGTATGGCAGGAAAAGTGGAACACATTTATAGCAGAAAACTCATAACCATGACAAAAACACTTTAGAAAATTAAACTGCAGGGTAAAAAACACATTTACGCACAGGGAAAGATTATAAGGAAAATATTTCTGCCAGATTTTATCTGACCACAAGAGGTGGTTTACAGTATGTTTACATTATTCAATAGCTTCAATTTGAATGggttttaaaatataatgtatttctGTGATGCAAAGCTACATGCAGCATTACTCAAGTCTCACATAACACTTCTGAAATTATTCCAACAtgttgatttgctgctcaagaactAATAACTATAggttttttaaccttttttttataaagtattataCATGTGTTCACTGTTATGTTTGATTACCTTAAAGCATCCTTTCTGAATAAAAGCATTGGCTTCTTTAAATCAAGCTACATCTTGCTGACCCTGAATGTTTTGAACATTAGTAAACAGAATGTTACTCACCGCGGCATAACCAAGTACATCATCAATGGGGATTAACTGATGTCAGTATCAATACAACA
>TCONS_00055249
ATGAGTAGCATAAGCTTGAAGGATGTGAGTGCAGCAGTCATGGTGGTGCTGCTGGTGTGTGTGAGCGAGTGTAAATCAATGCCAGATCCCCGTCAGAGAGAGCAGATGCTGCAGCAGGAGCTCTTACAGCAGATCGGGGGAAACATGGAGCTCAATGAAGCCGAAAAGCGGATGGATTCACTGCTGTACATGCTGAAGATGAAGGAAATCACCCTTTCACCTTTCCCACCGGCCAATCACTTCTTCAAAGTGCGGCACATCATACAGCAAAGCCCGATATTCAAACTGCTGCAGAAAATGCCAAAAGGTGCTGCCCTTCACATCCATAACTCTGCTATGGTGAGTGTTGATTGGCTGCTGAACGCCACATACAGGCCTAACTGCTACATCTGCTTCACTTGGGACGGATCGGTTCGGTTCATGTTCTCCACCAGTACACCCTTTCCGCGCTGGGGATGCTCTTTTTGGAAACGGCTAGACATTTTAAGAGCCAGTCTTGGTGATGTCACTTCCTTTGATAACAGCTTGATGCGTAATCTAACGCTTTTTACGGAAGACCCGGAGACGTCTTATCCCACACAGGACTATATATGGAAGCGGTTTGAGAAGATTTTCATTGCTCTGTCTGGGCTGATCACATATGCTCCTGTCCTGAAGGATCACATCTACCAGGGTTTGAAAGAGCTTTATGAAGACAACATCATGTATGTGGAGCTGAGGATTGGACAGGCCAAGGCATATGAACTGGACGGCACTACCCATGACAGAGCGTGGACTATCGAGGTCTACAGAAACATCACTGAGCAGTTCAGAGCAAATCATCCAGACTTTATAGGAACTCGTGTAATCCTCTCCGCTCACAGGTCTTCTAGTGTGTCTCGAGTGAAGCAGGCTGTGCAGGAGGCCATTGAGATgcagagaaaatatccagagatTGTTGCAGGATTTGACCTGGTAATCTCACCCTTGCCTTGGGCTACAATTCACATCAATGCAAATATTTATGTGAAAAACACAGCAATCATTTCATTAAATGCTGTTATTATAGTCTGTTTACACAAGTACACTACTTGA
>TCONS_00055250
GGTTCCCATAGAGGAAATACGCGTCATGTGACGTCTGTGTCATCGTAGACTGAGAATCAGCTGATCCCTCCAGTCTATTTTCACGGCTCTGACACTGTCACGATCAACCCTTTTCGAGTAAATTTAAAATCTAAAGGCTTTCAGGATTATTTTCGAGCTGTATTTGCAAAGCAGACGCCTTTCCTCTGCCGCAAACCGAGCTTTATCTCTCGGCGGAGTTTAAAATCCCCTTAAAGCAGCAGGAGCAGGATCTGCAGTCATGGCGCTCAGCGATGCCGACGTCCAGAAACAGATCAAGCACATGATGGCTTTCATTGAGCAGGAGGCCAATGAAAAAGCCGAGGAGATAGACGCCAAGGCGGAGGAGGAGTTTAACATTGAGAAAGGTCGACTGGTTCAGACCCAGCGCTTGAAGATCATGGAGTATTACGAAAAGAAGGAGAAACAGATCGAACAGCAGAAGAAAATTCAAATGTCCAACCTGATGAATCAGGCCAGACTGAAGGTCCTGAAGGCCAGAGATGACATGATTGCGGATTTACTAAACGACGCACGTCAGCGACTAGCGAATGTAGCCAGAGATCCGTCCAGATACGCGGCTCTGATGGACGGACTGGTTCTGCAGGGTTTTTACCAGCTGCTGGAACCTAAAGTGACCATCCGTTGCCGCAAACAGGATGTGGGGATTGTGCAGGCCGCCGTGCAGAAAAACATCTCCATCTACAAAGCAGCAGTAAAGAACAATCTAGAAGTGCGCATCGACCAAGACAACTtcctctctccagaaatctCTGGAGGTATTGAGCTCTATAATGCGGACGGGAAAATTAAAGTGGCAAACACTCTGGAGAGCCGACTGGAGCTCATCGCACAGCAGATGATGCCTGAAATACGAGTCGCCCTGTTTGGTGCGAACCAGAACCGCAAGTTCATGGACTGATGGATCTTTCTGGAGATCGGCAGTGTTttgatgttgtatttttattttgatgttaaaaatccATTCCTGCGTCTCTATCTGTACTGTATTTAAGAAGAcatcacctgtgtgtgtgtgtgtgcgtatgatTCATCATTGCTGTATAAAGATCAAAATAGTGTCCTGCACATTTCTGTGTTAGATTATGAATAAATTAAAGCTCCGTTATGTTCCTATAAAGTCTTAAAGTGATGCATAACCCTCGCTTCATgaagaaaatatgacttttttttttatttgcattcctGTAATGAGGAGCATGATCTGTATATCTGAAGCAAACGTGTCTGTCGATGATGCAAAAAGACTATATTGATGTGAAAACTATAATGAAAACCCATATGGCCCAGA

Function

symbol description
ada2b Predicted to enable adenosine deaminase activity. Acts upstream of or within blood vessel endothelial cell differentiation and neutrophil differentiation. Predicted to be located in extracellular region. Predicted to be active in extracellular space. Is expressed in several structures, including cardiovascular system; gill; liver; notochord; and pleuroperitoneal region. Human ortholog(s) of this gene implicated in Sneddon syndrome. Orthologous to human ADA2 (adenosine deaminase 2).

GO:

id name namespace
GO:0046103 inosine biosynthetic process biological_process
GO:0006154 adenosine catabolic process biological_process
GO:0030223 neutrophil differentiation biological_process
GO:0060837 blood vessel endothelial cell differentiation biological_process
GO:0005615 extracellular space cellular_component
GO:0019239 deaminase activity molecular_function
GO:0004000 adenosine deaminase activity molecular_function

KEGG: NA

ZFIN:

id description
ZDB-GENE-020419-11 Contributes to P-type potassium:proton transporter activity. Acts upstream of or within several processes, including caudal fin development; fin regeneration; and notochord cell vacuolation. Predicted to be part of proton-transporting two-sector ATPase complex, catalytic domain. Is expressed in several structures, including digestive system; eye; gonad; heart; and unfertilized egg. Human ortholog(s) of this gene implicated in autosomal recessive cutis laxa type IIC. Orthologous to several human genes including ATP6V1E1 (ATPase H+ transporting V1 subunit E1).
ZDB-GENE-041210-77 Predicted to enable adenosine deaminase activity. Acts upstream of or within blood vessel endothelial cell differentiation and neutrophil differentiation. Predicted to be located in extracellular region. Predicted to be active in extracellular space. Is expressed in several structures, including cardiovascular system; gill; liver; notochord; and pleuroperitoneal region. Human ortholog(s) of this gene implicated in Sneddon syndrome. Orthologous to human ADA2 (adenosine deaminase 2).

Ensembl:

ensembl_id ENSDARG00000015623 ENSDARG00000030694

RNA

RNA id representative length rna type GC content exon number start site end site
TCONS_00055248 False 2228 mRNA 0.44 10 5225552 5240128
TCONS_00055249 False 1074 mRNA 0.47 6 5229657 5239904
TCONS_00055250 True 1330 mRNA 0.45 9 5240126 5247335

Neighbor

gene id symbol gene type direction distance location
XLOC_028465 tmem209 coding downstream 116611 5094007 ~ 5108941 (-)
XLOC_028464 ahcyl2b coding downstream 133217 5025625 ~ 5092335 (-)
XLOC_028463 strip2 coding downstream 206439 4971042 ~ 5019113 (-)
XLOC_028462 NA coding downstream 257841 4962957 ~ 4967711 (-)
XLOC_028461 NA coding downstream 262660 4940467 ~ 4962892 (-)
XLOC_028467 snap91b coding upstream 13606 5260941 ~ 5302866 (-)
XLOC_028468 si:ch211-214j24.15 coding upstream 56873 5304208 ~ 5317006 (-)
XLOC_028469 osgep coding upstream 80297 5327632 ~ 5333971 (-)
XLOC_028470 si:dkey-14d8.1 coding upstream 115574 5362909 ~ 5371639 (-)
XLOC_028471 NA coding upstream 174411 5421746 ~ 5459469 (-)
XLOC_028450 FP102892.1 non-coding downstream 709044 4514438 ~ 4516508 (-)
XLOC_028446 CU468826.1 non-coding downstream 850848 4321168 ~ 4374704 (-)
XLOC_028444 NA non-coding downstream 1015088 4207590 ~ 4210464 (-)
XLOC_028472 NA non-coding upstream 180983 5428318 ~ 5441954 (-)
XLOC_028474 NA non-coding upstream 297667 5545002 ~ 5553182 (-)
XLOC_028478 NA non-coding upstream 445835 5693170 ~ 5745885 (-)
XLOC_028479 NA non-coding upstream 488035 5735370 ~ 5737345 (-)

Expression


Co-expression Network

Homologous

species gene id symbol gene type chromosome NCBI id location
grasscarp (Ctenopharyngodon idella) CI01000066_01829752_01832316 ATP6V1E1.L, ATP6V1E1, ATP6V1E1B coding CI01000066 null 1829716 ~ 1832316 (+)