XLOC_028475 (vegfab)


Basic Information

Item Value
gene id XLOC_028475
gene name vegfab
gene type coding
species zebrafish (Danio rerio)
category of species model fish

Chromosome Information

Item Value
chromosome id NC_007115.7
NCBI id CM002888.2
chromosome length 78093715
location 5568688 ~ 5597802 (-)
genome version GRCz11_2017_zebrafish_Genome

Sequence

>TCONS_00055270
CAAGTCTCTCTGCCGTCCTCGGGAAATGTTGGTGGAAATTCAGCAGGAGTACCCTGATGACACAGAGCATATCTTCATACCGTCCTGTGTGGTTCTCACCCGCTGTGCTGGGTGCTGCAATGATGAAATGATGGAATGCACCCCCACCGTCACATACAACATTACCTTGGAGATTAAGAGATTGAAACCTCTTCGTCATCAGGGTGACATTTTCATGAGTTTTGCTGAACACAGTGAATGCCAGTGTCGGATGAAAAAAGATCTTCCAAAGGAAATAGAAAATAGTCAGTGTGAGCCTTGCTGTTCTACATGTTCTGAAAGAAGAAGAAGGTTGTTTGTTCAAGACCCAGAGACATGTCAGTGCTCCTGCAAACACTCTGAAGCCGACTGCAGGTCTAGGCAACTAGAACTCAACGAAAGGACCTGCAGGGACCTGTGACCCTATTGTGTGCTGCGCTGGGGGCCGATGTCATCACCGAGGGCCCCAGAGATGGAAAAATGACAGGAGGCCTATGGTTTCTGGCTGTAACGCGACCCTGCAGATGCTCCAGTCATGCCTGCTATGAGAGGCCTCCGCATGGGCCTCAACCCTCTGGACGG
>TCONS_00055271
CTTTGCTGTTCGCGTGCTCCAGTTATTTATTGTGACGCTTCTGTATTTTTCAGCTGTCAAGagtGCCTACATACCCAGAGAGGGAGGCAGAAGCACATATGACGTAGTGCCATTCATGGAGGTGTATAACAAGTCTCTCTGCCGTCCTCGGGAAATGTTGGTGGAAATTCAGCAGGAGTACCCTGATGACACAGAGCATATCTTCATACCGTCCTGTGTGGTTCTCACCCGCTGTGCTGGGTGCTGCAATGATGAAATGATGGAATGCACCCCCACCGTCACATACAACATTACCTTGGAGATTAAGAGATTGAAACCTCTTCGTCATCAGGGTGACATTTTCATGAGTTTTGCTGAACACAGTGAATGCCAGTGTCGGATGAAAAAAGATCTTCCAAAGGAAATAGAAAAAAAACCCCGGAAGGGCAAAGGCCAAAAGCGAAAGGGAAAGAAAAACCGTGAAAAAAAGCGGGATTTGTGCATGGCCCCATCCTGCCTAACTTCAGCTATTCACACTCTACAACCGTCCCTTTGGACCCTCAGAAGGGGCAAAACCGTGGTTCCAGACCAGGGTGGCTCAAAAATTAGTCAGTGTGAGCCTTGCTGTTCTACATGTTCTGAAAGAAGAAGAAGGTTGTTTGTTCAAGACCCAGAGACATGTCAGTGCTCCTGCAAACACTCTGAAGCCGACTGCAGGTCTAGGCAACTAGAACTCAACGAAAGGACCTGCAGATGTGACAAACCAAGGAGGTGAACCGAACTGACTTGAGAACGGACATGAAGGAATATTTCACCAATAATTCACAGCACTTTGAACTTTTTCAGCTTTGAACTATGTGTCTCATTTTTCCACCGTGGAAATATCGAGAGAATGAAGTGAAGTGGTTGGAGATGGATGTGGGAGGGTTTAGTAGTCAATGAAATGTCTGTTTGTATATTTTCATGATTTTCATGTGTGTGCTAAGCAAACCGAGAGACTCGGAGCACAGGATTTGATTTGCTGCTAAAAGGTCTTCAGACCTGCGTAAATGTTTCTGATCTTGGCTGGTGTGTGTAAAGTCATACCCGCGTTCACTCAATGAAACACATCACTGGATTTGGGTCTGCTGTgcagtttgtttttgtgaatctaaATGTAAACAAGTGCAAACAAGTTGTTTGGAAGACTAATGCGTCAGCGTCCACTACGCGCTGTGGAATCATTCCTCCCAGTACATGAACAATGAGCACAACGTGTGTGTTTTTAGAGACAGACGATTGACTGGAGTTTCAACGGAAAGCGAACTGATTCTGCCATTGGAATGTCACAGTGGAAACCCGCTGCCTGCTGTGGTAAATGTTTGCACCAGAGCTCTGACCTTGACGAGGCAAACCCTACAGAATTTCGGTCGTATTCACTCCTTAAAGGGATATTCATTCTTTGACATGCTTGGAAACCACTTTTGAGTAAATCCTGTGATTTAGATTCCATGTTTCCACACTACTGGGGATTTAAGATGACGATTTTGTGCTACGCTTTCGTTGTCGTTTCAGCTCGTCTTGGAATTTTAGTCCAAATCTATTCCCCCTCCAAACAATTcagtaatttataatttttttttagaatattttcagtgttttttctcTTTGTATTTAATTTGACCTATTTATGTGCAGTGTTATTCTTGCCCCATTTTGTCTGCAAAACTCCACACTGTTGTTCtgagaaaaaaaagcttttattttccGTAGCTGAAAAGAGAAACATTCCTATTACTGATCAGTGAGTTGTGTTGCCAACTGCCTTGACTTTGCTGCCTCtctgcacatgtgtgtgtgtgtgtgtgccgtgtGAGCTCTAACAAACAAACTGTAAATGTGATTTGGTGTGGATACGAGGTTAGTGTTTGTGCGCGTGCACGTGCGAGTATGTTTTGGCGAAACACTCTTGATGTCAGTGTGACATACATATTGAATAACAATATAGCAGCCAAATGTAAATATAGGCCAAACCCACGTCACCATTTACTTCTACTATAATAAGATCTAACAAGCTGAAACAGTATGCTGAGGTGTGGTCTGATTCGATTGGAgttttacagtttaaacattatttatttactctgtGTATGTAAATATGTTGAATATTAACTTTTTTCGTGTCTGTAATGTAGAAcagcatatttattttcaaattataTTGCTCTTTTTCTATAAAA
>TCONS_00055272
ATTCATAACGACAAGAGAGAGAAATCCAGAAGACAAATCTTAACAGGAAGCGGAATTAAAGCAGTGCTCATCCGTATGGACTAAAAGTACGCATGGATATCGCCTTCTCTCTTCAGCGCCTTTGTGTTCACTGATATCTCTGTATACTCCGCTAATAACACAGTGTCGGCAATACTCAAAGTTGTAACAGAGAGTGCGGTTTTTTCCATTCTGCGTCCCTTTACCAATGAACCCAACGCACTTGGAGACGGGTGGCAGTCTAAGCATGGGATTACTTCTGTGATGTGGATTGTAATAGCCTTGGAAGAAAAATTTGATTTACTTCTCAACAATGTGAGAGGACCCGCGTCCTGGATTCTCATATTCCTGGATATTCTGAAAATCATCGGCAACAGCTGAGAGACGCTGTAACATACTAGCTGTGGAGCTCAGTCTCGCTCTCTCAGGTGTCTGCATGCGTGTTTTGGGACCAACATGGGATTCTTGTTGCCCCTATAGGTCGGACCCTGTGTGAAGAAGCCGCTACTCATGTCTAACTTGCTTTCTGAGACCTTTACCAATGCTTTTGCTAAAGTGCGCCTATCATCGGATAGggttttaaaaagatttattcGCCTTTTAAATTCAATCATGAACTTTGCTGTTCGCGTGCTCCAGTTATTTATTGTGACGCTTCTGTATTTTTCAGCTGTCAAGagtGCCTACATACCCAGAGAGGGAGGCAGAAGCACATATGACGTAGTGCCATTCATGGAGGTGTATAACAAGTCTCTCTGCCGTCCTCGGGAAATGTTGGTGGAAATTCAGCAGGAGTACCCTGATGACACAGAGCATATCTTCATACCGTCCTGTGTGGTTCTCACCCGCTGTGCTGGGTGCTGCAATGATGAAATGATGGAATGCACCCCCACCGTCACATACAACATTACCTTGGAGATTAAGAGATTGAAACCTCTTCGTCATCAGGGTGACATTTTCATGAGTTTTGCTGAACACAGTGAATGCCAGTGTCGGATGAAAAAAGATCTTCCAAAGGAAATAGAAAATAGTCAGTGTGAGCCTTGCTGTTCTACATGTTCTGAAAGAAGAAGAAGGTTGTTTGTTCAAGACCCAGAGACATGTCAGTGCTCCTGCAAACACTCTGAAGCCGACTGCAGGTCTAGGCAACTAGAACTCAACGAAAGGACCTGCAGATGTGACAAACCAAGGAGGTGAACCGAACTGACTTGAGAACGGACATGAAGGAATATTTCACCAATAATTCACAGCACTTTGAACTTTTTCAGCTTTGAACTATGTGTCTCATTTTTCCACCGTGGAAATATCGAGAGAATGAAGTGAAGTGGTTGGAGATGGATGTGGGAGGGTTTAGTAGTCAATGAAATGTCTGTTTGTATATTTTCATGATTTTCATGTGTGTGCTAAGCAAACCGAGAGACTCGGAGCACAGGATTTGATTTGCTGCTAAAAGGTCTTCAGACCTGCGTAAATGTTTCTGATCTTGGCTGGTGTGTGTAAAGTCATACCCGCGTTCACTCAATGAAACACATCACTGGATTTGGGTCTGCTGTgcagtttgtttttgtgaatctaaATGTAAACAAGTGCAAACAAGTTGTTTGGAAGACTAATGCGTCAGCGTCCACTACGCGCTGTGGAATCATTCCTCCCAGTACATGAACAATGAGCACAACGTGTGTGTTTTTAGAGACAGACGATTGACTGGAGTTTCAACGGAAAGCGAACTGATTCTGCCATTGGAATGTCACAGTGGAAACCCGCTGCCTGCTGTGGTAAATGTTTGCACCAGAGCTCTGACCTTGACGAGGCAAACCCTACAGAATTTCGGTCGTATTCACTCCTTAAAGGGATATTCATTCTTTGACATGCTTGGAAACCACTTTTGAGTAAATCCTGTGATTTAGATTCCATGTTTCCACACTACTGGGGATTTAAGATGACGATTTTGTGCTACGCTTTCGTTGTCGTTTCAGCTCGTCTTGGAATTTTAGTCCAAATCTATTCCCCCTCCAAACAATTcagtaatttataatttttttttagaatattttcagtgttttttctcTTTGTATTTAATTTGACCTATTTATGTGCAGTGTTATTCTTGCCCCATTTTGTCTGCAAAACTCCACACTGTTGTTCtgagaaaaaaaagcttttattttccGTAGCTGAAAAGAGAAACATTCCTATTACTGATCAGTGA

Function

symbol description
vegfab Predicted to enable chemoattractant activity; growth factor activity; and vascular endothelial growth factor receptor 1 binding activity. Involved in phosphorylation. Acts upstream of or within sprouting angiogenesis. Predicted to be located in membrane. Predicted to be integral component of membrane. Predicted to be active in extracellular space. Is expressed in nervous system; pronephros; and vasculature. Human ortholog(s) of this gene implicated in several diseases, including autoimmune disease (multiple); gastrointestinal system cancer (multiple); hematologic cancer (multiple); hypertension (multiple); and reproductive organ cancer (multiple). Orthologous to human VEGFA (vascular endothelial growth factor A).

GO:

id name namespace
GO:0045766 positive regulation of angiogenesis biological_process
GO:0038084 vascular endothelial growth factor signaling pathway biological_process
GO:0002040 sprouting angiogenesis biological_process
GO:0050930 induction of positive chemotaxis biological_process
GO:0001525 angiogenesis biological_process
GO:0048010 vascular endothelial growth factor receptor signaling pathway biological_process
GO:0060754 positive regulation of mast cell chemotaxis biological_process
GO:0016310 phosphorylation biological_process
GO:0001934 positive regulation of protein phosphorylation biological_process
GO:0001666 response to hypoxia biological_process
GO:0001938 positive regulation of endothelial cell proliferation biological_process
GO:0005615 extracellular space cellular_component
GO:0016020 membrane cellular_component
GO:0016021 integral component of membrane cellular_component
GO:0005515 protein binding molecular_function
GO:0008201 heparin binding molecular_function
GO:0005172 vascular endothelial growth factor receptor binding molecular_function
GO:0043183 vascular endothelial growth factor receptor 1 binding molecular_function
GO:0008083 growth factor activity molecular_function
GO:0042056 chemoattractant activity molecular_function

KEGG: NA

ZFIN:

id description
ZDB-GENE-030131-4605 Predicted to enable chemoattractant activity; growth factor activity; and vascular endothelial growth factor receptor 1 binding activity. Involved in phosphorylation. Acts upstream of or within sprouting angiogenesis. Predicted to be located in membrane. Predicted to be integral component of membrane. Predicted to be active in extracellular space. Is expressed in nervous system; pronephros; and vasculature. Human ortholog(s) of this gene implicated in several diseases, including autoimmune disease (multiple); gastrointestinal system cancer (multiple); hematologic cancer (multiple); hypertension (multiple); and reproductive organ cancer (multiple). Orthologous to human VEGFA (vascular endothelial growth factor A).

Ensembl:

ensembl_id ENSDARG00000034700

RNA

RNA id representative length rna type GC content exon number start site end site
TCONS_00055270 False 600 mRNA 0.50 5 5568688 5595237
TCONS_00055271 False 2198 mRNA 0.42 9 5587183 5597167
TCONS_00055272 True 2227 mRNA 0.43 7 5587615 5597802

Neighbor

gene id symbol gene type direction distance location
XLOC_028474 NA coding downstream 15506 5545002 ~ 5553182 (-)
XLOC_028473 BX324164.5 coding downstream 29936 5498230 ~ 5538752 (-)
XLOC_028471 NA coding downstream 109219 5421746 ~ 5459469 (-)
XLOC_028472 NA coding downstream 126734 5428318 ~ 5441954 (-)
XLOC_028470 si:dkey-14d8.1 coding downstream 197049 5362909 ~ 5371639 (-)
XLOC_028476 rsph9 coding upstream 47449 5645251 ~ 5652030 (-)
XLOC_028477 tmem63a coding upstream 67380 5665182 ~ 5691257 (-)
XLOC_028478 NA coding upstream 95368 5693170 ~ 5745885 (-)
XLOC_028479 NA coding upstream 137568 5735370 ~ 5737345 (-)
XLOC_028480 NA coding upstream 141208 5739010 ~ 5739938 (-)
XLOC_028462 NA non-coding downstream 600977 4962957 ~ 4967711 (-)
XLOC_028461 NA non-coding downstream 605796 4940467 ~ 4962892 (-)
XLOC_028487 NA non-coding upstream 515639 6113441 ~ 6116670 (-)
XLOC_028488 NA non-coding upstream 579784 6177586 ~ 6252483 (-)

Expression


Co-expression Network