XLOC_028503 (lta4h)


Basic Information

Item Value
gene id XLOC_028503
gene name lta4h
gene type coding
species zebrafish (Danio rerio)
category of species model fish

Chromosome Information

Item Value
chromosome id NC_007115.7
NCBI id CM002888.2
chromosome length 78093715
location 7653607 ~ 7673165 (-)
genome version GRCz11_2017_zebrafish_Genome

Sequence

>TCONS_00055304
ATTCGCAGCGCGAGCCGAGTGCTCTCTGCTCAACCATGACTCCAGTTTCAGACCCTAGCTCCTTCTCCTCGCTCTCCAAGTGCTCTACCAAGCACTTAAACCTCATTTACCATGTCGACTTTGACAGGCATGTGCTCAAAGGGAAAGTCGCCCTGACTGTGGAGGTCCTGGAGGATAAATTCTCTTCTCtgACCCTGGACTCTAAGGACCTGAAGATCTCTAAGGTGTCTGCGAATGGCCAAGCTGCAAAGTTTGAACTTGGAGCCAAGCATAAATTTAAGGGATCCCCTTTGGAAATCACCCTGCCTTTTGAACTCTCACGcGGTCAGCATGTGATTGTGGAGATCGAATATGAGACGTCTCCTACTGCCACTGCTCTTCAATGGTTAACACCCAAACAGACTGCTGGGAAAAAACATCCATACCTTTTCAGCCAATGCCAGGCCACTCATTGCAGGACCATGGTGCCTTGCCAGGACACTCCATCAGTGAAGCACACTTACTATGCCCAGGTTTCTGTCCCGAGAGAGCTGGTGGCATTGATGAGTGCATTGCGAGATGGGCAGGAACCAGATCCAAGTGACAGCAGCAGAGTCATCTATCGCTTCAGACAGCCGGTCCCCATGCCTTCTTACCTTATCGCCATTGTAGTTGGTGCTTTGGAAAGCAGGGAAATCGGCCCAAGGTCTAGAGTTTGGTCTGAGAAGGAATATGTGGATGAAGCTGCATATGAGTTTGCAGAGACTGAGACCATGTTAAAGACGGCTGAGAGTCTGGCAGGGCCATATGTTTGGGGCCAGTATGATGTCCTGGTTCTGCCTCCATCCTTCCCATATGGAGGCATGGAGAACCCCTGCCTCACATTTGTCACTCCAACTGTGTTGGCTGGAGACAGATCTCTTGCTGGTgTCATTGCTCATGAGATTTCCCACAGCTGGACAGGAAACCTGGTGACCAACAGGACTTGGGAGCATTTCTGGCTAAATGAAGGTCATACGGTGTATATCGAGAGAATGATAGCCAGGTGTATGGAGGGTGAGCAGCTCAGGCAGTTTAAAGGCATTGGAGGATGGAAAGAACTTCATGAGTCTGTGAAACAGTTTGGAGCAAATAATGTCCTCACAAACCTGGTCCCAAATCTGCATGAGGTGGACACAGATGAAGCCTTTTCCTCAGTGCCCTATGAGAAGGGATTTGCTCTGCTTTATCATCTGGAGGAACTGATGGGAGGCCCAGAGGTTTTCATGGGATTCGTGAAGTCCTACATTCAGCTGTTTGCCTACGGCAGTGTAACAACAGAGGAATGGAAGAACTATCTGTTCACTTACTTTAAAGACAAGGTGGACATCTTGAATAAAGTGGACTGGAATGCATGGATGCACACTCCAGGAATGGCCCCCGTCAGACCACAGTATGACACCACTATGGCGGACGCCTGCACTTCTCTGTGTCAGAAATGGGTGAAGGCAAAGGAAGCTGACCTCGCAAGTTTCACTGAGGCAGATGTGAAGCAATTGAACTCGCCTCAGCTTATTGAGTTTATGGCTTTGCTGCTCCAAGAGGATCCCCTTCCTCTGTCCCACGTGAAGAAGATGGGGGAGGTTTACAAGCTGAACAATATTAAAAATGCAGAGGTTCGCTTCAGGTGGTTGCGCATCTGTGTAAAGGCTCAATGGGAAGAAGCTGTTCCTTTGGCACTTAAAATGGCAACCGAACAGGGCAGAATGAAATTCACTCGCCCACTTTTTAAGGAAGTGTACAACTTCTCCAAGTACAGTGATGAAGCTGTGAAGACTTTTAAGGAGATCCGTGGATCACTGCATCCAGTCACTGCAATGCTGGTGGCCAAGGATCTGAAAATCGATGGCTAGAACTCTGCCTTCTTTCCTATTCTCCAGCATATCAGTCCTCGGACACATCCACAACGCTTTTCTCTTCACTGGCCAAAGCTTGCCTTTTTATAATGTCTTGATGGAGGTTTCAGTCTCAGGAACAAAACCATTTCAGTATCATGTAGTTTAGTGCTGTAAAAAACCATCGCATCTTAATCTGAAAGTTCCACTTTTGTCTGTTTATATAACATGTCAAAAGTACTGTTCTGTGCTAAACTCATCAATAAACTGTTTCTGCTCCTTTGTCCAATCAATAAAA
>TCONS_00055305
CAGTTTCAGACCCTAGCTCCTTCTCCTCGCTCTCCAAGTGCTCTACCAAGCACTTAAACCTCATTTACCATGTCGACTTTGACAGGCATGTGCTCAAAGGGAAAGTCGCCCTGACTGTGGAGGTCCTGGAGGATAAATTCTCTTCTCtgACCCTGGACTCTAAGGACCTGAAGATCTCTAAGGTGTCTGCGAATGGCCAAGCTGCAAAGTTTGAACTTGGAGCCAAGCATAAATTTAAGGGATCCCCTTTGGAAATCACCCTGCCTTTTGAACTCTCACGcGGTCAGCATGTGATTGTGGAGATCGAATATGAGACGTCTCCTACTGCCACTGCTCTTCAATGGTTAACACCCAAACAGACTGCTGGGAAAAAACATCCATACCTTTTCAGCCAATGCCAGGCCACTCATTGCAGGACCATGGTGCCTTGCCAGGACACTCCATCAGTGAAGCACACTTACTATGCCCAGGTTTCTGTCCCGAGAGAGCTGGTGGCATTGATGAGTGCATTGCGAGATGGGCAGGAACCAGATCCAAGTGACAGCAGCAGAGTCATCTATCGCTTCAGACAGCCGGTCAGTGTTTCGTCCTCGTTCTGTTGGATTCC

Function

symbol description
lta4h Predicted to enable aminopeptidase activity; epoxide hydrolase activity; and leukotriene-A4 hydrolase activity. Acts upstream of or within several processes, including epiboly involved in gastrulation with mouth forming second; neutrophil chemotaxis; and response to bacterium. Predicted to be located in cytoplasm. Predicted to be active in cytosol and nucleus. Is expressed in intestinal bulb; macrophage; and neutrophil. Orthologous to human LTA4H (leukotriene A4 hydrolase).

GO:

id name namespace
GO:0006954 inflammatory response biological_process
GO:0009617 response to bacterium biological_process
GO:0044255 cellular lipid metabolic process biological_process
GO:0019370 leukotriene biosynthetic process biological_process
GO:0055113 epiboly involved in gastrulation with mouth forming second biological_process
GO:0006508 proteolysis biological_process
GO:0030593 neutrophil chemotaxis biological_process
GO:0005634 nucleus cellular_component
GO:0005737 cytoplasm cellular_component
GO:0004463 leukotriene-A4 hydrolase activity molecular_function
GO:0046872 metal ion binding molecular_function
GO:0016787 hydrolase activity molecular_function
GO:0008233 peptidase activity molecular_function
GO:0004301 epoxide hydrolase activity molecular_function
GO:0008237 metallopeptidase activity molecular_function
GO:0008270 zinc ion binding molecular_function

KEGG:

id description
ko00590 Arachidonic acid metabolism
ko01002 Peptidases and inhibitors

ZFIN:

id description
ZDB-GENE-040426-2477 Predicted to enable aminopeptidase activity; epoxide hydrolase activity; and leukotriene-A4 hydrolase activity. Acts upstream of or within several processes, including epiboly involved in gastrulation with mouth forming second; neutrophil chemotaxis; and response to bacterium. Predicted to be located in cytoplasm. Predicted to be active in cytosol and nucleus. Is expressed in intestinal bulb; macrophage; and neutrophil. Orthologous to human LTA4H (leukotriene A4 hydrolase).

Ensembl:

ensembl_id ENSDARG00000006029

RNA

RNA id representative length rna type GC content exon number start site end site
TCONS_00055304 False 2151 mRNA 0.47 19 7653607 7673165
TCONS_00055305 True 607 lncRNA 0.50 5 7666715 7673123

Neighbor

gene id symbol gene type direction distance location
XLOC_028501 NA coding downstream 418 7598210 ~ 7653189 (-)
XLOC_028502 NA coding downstream 5378 7645101 ~ 7648229 (-)
XLOC_028500 NA coding downstream 72174 7578861 ~ 7581433 (-)
XLOC_028499 NA coding downstream 87100 7557414 ~ 7566507 (-)
XLOC_028498 NA coding downstream 107490 7538015 ~ 7546117 (-)
XLOC_028504 BX649411.3 coding upstream 6814 7679979 ~ 7680095 (-)
XLOC_028505 cdk17 coding upstream 45689 7718854 ~ 7811925 (-)
XLOC_028506 mcm10 coding upstream 177964 7851129 ~ 7869731 (-)
XLOC_028507 nudt5 coding upstream 197219 7870384 ~ 7876005 (-)
XLOC_028508 NA coding upstream 298517 7971682 ~ 7973335 (-)
XLOC_028515 CU695020.1 non-coding upstream 468184 8141349 ~ 8141466 (-)
XLOC_028516 NA non-coding upstream 540005 8213170 ~ 8214435 (-)
XLOC_028517 NA non-coding upstream 546296 8219461 ~ 8219991 (-)

Expression


Co-expression Network