XLOC_028712 (cradd)


Basic Information

Item Value
gene id XLOC_028712
gene name cradd
gene type coding
species zebrafish (Danio rerio)
category of species model fish

Chromosome Information

Item Value
chromosome id NC_007115.7
NCBI id CM002888.2
chromosome length 78093715
location 18383253 ~ 18416566 (-)
genome version GRCz11_2017_zebrafish_Genome

Sequence

>TCONS_00055667
ATGGACCCAAAACACAAAAAACTGCTCCGAACACAGCGGCTTTTTCTGTCCGAGGAGCTTTTAGTGGACGATTTAATCATTCAGTATTTATATCAAGAGGAGATACTGACGGAGAGCCATTTAGAGGAGATTCAGTCTGAGTCGTCAAGCAGAAATAAAACGTTAAAGCTGCTGGATATTTTACCGAGCCGCGGAGCGACAGCCTTCCATCACTTCATAAAGTCACTGGAGAAAGACTTTCCCTGGATCAGAGacaaactgctgcaactaaacgaGGAAGAAGAGTCTCCTCCTCCGCCCTTCACAGttcagtgtggtgttCCTGACCACATCCTTCTGACCGTACCAACCACCCTGCATCTGAATCAGCTGGCATCCCGTCTGGGCTCAGAGTGGAAGTCTGTGCTGCTGGATCTGGGCCTGTCCTGTGCGGATCTGTACCGGTGCTGCTCTGACCACCCGCTTGCTGTTCAGAGTCAGGTGCTCGCTGGGCTGGTGATGTGGACGCAGAGGAACGGAAGAGGGGCCACGGTGCAGCGGCTGATCCAGAGCCTGCAGGCTGCAGATGTCCCGCCATCTGTGCTCCAACAGGTGTTTAAGTGA

Function

symbol description
cradd Predicted to enable death domain binding activity and protease binding activity. Predicted to be involved in positive regulation of NF-kappaB transcription factor activity. Predicted to act upstream of or within regulation of apoptotic process and signal transduction. Predicted to be part of CBM complex. Human ortholog(s) of this gene implicated in autosomal recessive non-syndromic intellectual disability. Orthologous to human CRADD (CASP2 and RIPK1 domain containing adaptor with death domain).

GO:

id name namespace
GO:0042981 regulation of apoptotic process biological_process
GO:0051092 positive regulation of NF-kappaB transcription factor activity biological_process
GO:0007165 signal transduction biological_process
GO:0032449 CBM complex cellular_component
GO:0005737 cytoplasm cellular_component
GO:0070513 death domain binding molecular_function
GO:0002020 protease binding molecular_function

KEGG: NA

ZFIN:

id description
ZDB-GENE-041010-168 Predicted to enable death domain binding activity and protease binding activity. Predicted to be involved in positive regulation of NF-kappaB transcription factor activity. Predicted to act upstream of or within regulation of apoptotic process and signal transduction. Predicted to be part of CBM complex. Human ortholog(s) of this gene implicated in autosomal recessive non-syndromic intellectual disability. Orthologous to human CRADD (CASP2 and RIPK1 domain containing adaptor with death domain).

Ensembl:

ensembl_id ENSDARG00000028192

RNA

RNA id representative length rna type GC content exon number start site end site
TCONS_00055667 True 603 mRNA 0.52 2 18383253 18416566

Neighbor

gene id symbol gene type direction distance location
XLOC_028711 plxnc1 coding downstream 67341 18281954 ~ 18315912 (-)
XLOC_028710 uhrf1bp1l coding downstream 102093 18207655 ~ 18281160 (-)
XLOC_028708 anks1b coding downstream 180962 17886838 ~ 18202291 (-)
XLOC_028709 BX901882.1 coding downstream 193733 18189406 ~ 18189520 (-)
XLOC_028707 NA coding downstream 500323 17875071 ~ 17882930 (-)
XLOC_028713 socs2 coding upstream 15616 18432182 ~ 18436899 (-)
XLOC_028714 sco2 coding upstream 37136 18453702 ~ 18455480 (-)
XLOC_028715 rint1 coding upstream 83446 18500012 ~ 18512550 (-)
XLOC_028716 cdkn1ba coding upstream 176177 18592743 ~ 18595525 (-)
XLOC_028717 CDPF1 coding upstream 180596 18597162 ~ 18606573 (-)
XLOC_028702 BX890572.1 non-coding downstream 645441 17736443 ~ 17737812 (-)
XLOC_028696 NA non-coding downstream 753809 17571295 ~ 17629444 (-)
XLOC_028690 NA non-coding downstream 1167030 17113379 ~ 17216223 (-)
XLOC_028719 dre-let-7b non-coding upstream 236582 18653148 ~ 18653241 (-)
XLOC_028720 dre-let-7a-3 non-coding upstream 237589 18654155 ~ 18654261 (-)
XLOC_028721 NA non-coding upstream 238116 18654682 ~ 18679692 (-)
XLOC_028722 NA non-coding upstream 296197 18712763 ~ 18714926 (-)
XLOC_028730 dre-mir-129-1 non-coding upstream 630900 19047466 ~ 19047555 (-)

Expression


Co-expression Network

Homologous

species gene id symbol gene type chromosome NCBI id location
grasscarp (Ctenopharyngodon idella) CI01000020_00959078_00971223 CRADD coding CI01000020 null 959078 ~ 971999 (+)