XLOC_028713 (socs2)


Basic Information

Item Value
gene id XLOC_028713
gene name socs2
gene type coding
species zebrafish (Danio rerio)
category of species model fish

Chromosome Information

Item Value
chromosome id NC_007115.7
NCBI id CM002888.2
chromosome length 78093715
location 18432182 ~ 18436899 (-)
genome version GRCz11_2017_zebrafish_Genome

Sequence

>TCONS_00055668
AGTCTTTTTAAATGAGGATTAAGTCGTTAAGGACGGgcgctcacacatacacacaaagctgaaaaaaaaaggttCGCTGGAATATAACTAAACTGCTGGAGTAAGTAATTATATGTGTCCTCCTCGCTTTGGTGCGCGCTATAACGCGTTTGGACGCACGGCGCGTGCGGTGCGCTTTTGGACAGACAGTGTCGCCGTTTGTGGAGTGCAGTGTCGCCTCCCAAAGAATCGATGCAAATACAAGGAAAAACGGGTCCCGACCTGCTGCGCATCAGGACGCACCGGACGACTGACAGAGAACCGATCAGTGCTTCCCATTAATAAATGATGGTGCCATTGAGCGTCTGTAACGCGAACCGCGCTGGACTTGATTGCTTACTGCTTTCACTAGACAAAAGatcGGCTCAGCCAAATAAAATCCACGGACGCTGTGGAAGACTTCTCACATGTTTTGGTTGATTGTAAGAGTCAGTCGTCTCTGAGGGATAATTATAGACATTGACTGGATGCAGAACGCGGTTCTCCAATGACCTGTCACTCATCCGACTCCACGGAAAGCATCGAGAATGAAAGGAGATCGCAATCCGAAACCCAAGTCGCCGACACCGAGCAGAGTCGCATTGCCACTGCCATGAGAGACCTTAAAAACACTGGCTGGTATTGGGGCAGCCTGACAGCCAATGAAGCCAAGGAGATCCTGCAGGACACGTCGGAGGGGACGTTTCTCGTCCGGGACAGCTCTCAGAGGGACTACCTCTTCACCATCTCCGCCATGACATCTGCGGGACCGACCAACCTGCGGATCGAATACAAGGACGGCAAGTTCAAGCTGGACTCTGTGGTGCTGGTCAAACCCAAACTCAAGCAGTTCGACAGCGTGGTGCATCTCGTGGAGCATTACGTGCAGCTGTCCCGGACGTCTTGTAAAGGCAGGACTAACCAAATCGCCCCGTCCAATGGTACCGTGCAGCTGCTTCTCACGACTCCGGTGTACACGGCCACGCCGTCCCTGCAGCACCTGTGCCGTATTGCCATCAATAAAACCACACGACGGGTACAAGAACTTCCTTTGCCCAACCGGCTGAAGGATTACCTGACAGACTACACTTATAATGTATAGAACCGATGGACAACCGTGACCACAAGTGCTGAACTTCTATTGATCATAGATCCAATGTAAATGGGGTGCTGAAGTCTTGTTTAGGATCATTTGCCTGCGATCCCTCTTCGTGTGCCCAAGGACTACTTTAAAGTACTTAAGAGTGAGCGGTCTGTCATTATTGtttaccctcatgtcattccaaaccttcTTTCTTCTGGTAAACTATATGTCCACGATAGTCAATGGAATCAAACACACAGCACTAGATTGCTCTGACTTTCATTGAATTTGCTAAATTTTTTCCAATTTCTCATGTTTGGGATGTCAACagggcgagtaaataatgacagaggtTGTATTTctggtgaactatcccattagtGCGCAGAACATCCTAACTAATGTTAAGTGTTCTTTATTGAGCACTTAACAAGTTTATGGCCTGTAGGTATTCTGCAGTCAGTTTTAAACGAGTGAGTGAGCAGTATAAGCTAGGCGCTGCCTACACTGAAACCTGTGGGTTAGGGAAATCTGTAGGTTACAGCCACCAGATAAACAAAGTGTGGCCATGCATCTCTTTTACAGGACGAGTTCACCCTCAAATAGGAAAAAGTCAATCCAAACtcaattttctttcttctgtggagCACAAAAACtcttctgtgtttttttcttcatttattaaaatt
>TCONS_00055669
ATGACCTGTCACTCATCCGACTCCACGGAAAGCATCGAGAATGAAAGGAGATCGCAATCCGAAACCCAAGTCGCCGACACCGAGCAGAGTCGCATTGCCACTGCCATGAGAGACCTTAAAAACACTGGCTGGTATTGGGGCAGCCTGACAGCCAATGAAGCCAAGGAGATCCTGCAGGACACGTCGGAGGGGACGTTTCTCGTCCGGGACAGCTCTCAGAGGGACTACCTCTTCACCATCTCCGCCATGACATCTGCGGGACCGACCAACCTGCGGATCGAATACAAGGACGGCAAGTTCAAGCTGGACTCTGTGGTGCTGGTCAAACCCAAACTCAAGCAGTTCGACAGCGTGGTGCATCTCGTGGAGCATTACGTGCAGCTGTCCCGGACGTCTTGTAAAGGCAGGACTAACCAAATCGCCCCGTCCAATGGTACCGTGCAGCTGCTTCTCACGACTCCGGTGTACACGGCCACGCCGTCCCTGCAGCACCTGTGCCGTATTGCCATCAATAAAACCACACGACGGGTACAAGAACTTCCTTTGCCCAACCGGCTGAAGGATTACCTGACAGACTACACTTATAATGTATAG

Function

symbol description
socs2 Predicted to enable 1-phosphatidylinositol-3-kinase regulator activity. Predicted to be involved in phosphatidylinositol phosphate biosynthetic process. Predicted to act upstream of or within intracellular signal transduction; negative regulation of receptor signaling pathway via JAK-STAT; and regulation of cell growth. Predicted to be located in cytoplasm. Predicted to be part of phosphatidylinositol 3-kinase complex. Human ortholog(s) of this gene implicated in endometrial cancer and ovarian carcinoma. Orthologous to human SOCS2 (suppressor of cytokine signaling 2).

GO:

id name namespace
GO:0046854 phosphatidylinositol phosphorylation biological_process
GO:0035556 intracellular signal transduction biological_process
GO:0001558 regulation of cell growth biological_process
GO:0016567 protein ubiquitination biological_process
GO:0046426 negative regulation of receptor signaling pathway via JAK-STAT biological_process
GO:0005942 phosphatidylinositol 3-kinase complex cellular_component
GO:0005737 cytoplasm cellular_component
GO:0005159 insulin-like growth factor receptor binding molecular_function
GO:0046935 1-phosphatidylinositol-3-kinase regulator activity molecular_function
GO:0008269 JAK pathway signal transduction adaptor activity molecular_function

KEGG:

id description
ko04630 JAK-STAT signaling pathway
ko04910 Insulin signaling pathway
ko04917 Prolactin signaling pathway
ko04935 Growth hormone synthesis, secretion and action
ko04930 Type II diabetes mellitus
ko04121 Ubiquitin system

ZFIN:

id description
ZDB-GENE-041210-171 Predicted to enable 1-phosphatidylinositol-3-kinase regulator activity. Predicted to be involved in phosphatidylinositol phosphate biosynthetic process. Predicted to act upstream of or within intracellular signal transduction; negative regulation of receptor signaling pathway via JAK-STAT; and regulation of cell growth. Predicted to be located in cytoplasm. Predicted to be part of phosphatidylinositol 3-kinase complex. Human ortholog(s) of this gene implicated in endometrial cancer and ovarian carcinoma. Orthologous to human SOCS2 (suppressor of cytokine signaling 2).

Ensembl:

ensembl_id ENSDARG00000045557

RNA

RNA id representative length rna type GC content exon number start site end site
TCONS_00055668 False 1791 mRNA 0.47 3 18432182 18436899
TCONS_00055669 True 594 mRNA 0.55 2 18432853 18434924

Neighbor

gene id symbol gene type direction distance location
XLOC_028712 cradd coding downstream 15616 18383253 ~ 18416566 (-)
XLOC_028711 plxnc1 coding downstream 116270 18281954 ~ 18315912 (-)
XLOC_028710 uhrf1bp1l coding downstream 151022 18207655 ~ 18281160 (-)
XLOC_028708 anks1b coding downstream 229891 17886838 ~ 18202291 (-)
XLOC_028709 BX901882.1 coding downstream 242662 18189406 ~ 18189520 (-)
XLOC_028714 sco2 coding upstream 16803 18453702 ~ 18455480 (-)
XLOC_028715 rint1 coding upstream 63113 18500012 ~ 18512550 (-)
XLOC_028716 cdkn1ba coding upstream 155844 18592743 ~ 18595525 (-)
XLOC_028717 CDPF1 coding upstream 160263 18597162 ~ 18606573 (-)
XLOC_028718 pparaa coding upstream 172640 18609539 ~ 18635005 (-)
XLOC_028707 NA non-coding downstream 549252 17875071 ~ 17882930 (-)
XLOC_028702 BX890572.1 non-coding downstream 694370 17736443 ~ 17737812 (-)
XLOC_028696 NA non-coding downstream 802738 17571295 ~ 17629444 (-)
XLOC_028690 NA non-coding downstream 1215959 17113379 ~ 17216223 (-)
XLOC_028719 dre-let-7b non-coding upstream 216249 18653148 ~ 18653241 (-)
XLOC_028720 dre-let-7a-3 non-coding upstream 217256 18654155 ~ 18654261 (-)
XLOC_028721 NA non-coding upstream 217783 18654682 ~ 18679692 (-)
XLOC_028722 NA non-coding upstream 275864 18712763 ~ 18714926 (-)
XLOC_028730 dre-mir-129-1 non-coding upstream 610567 19047466 ~ 19047555 (-)

Expression


Co-expression Network