XLOC_028716 (cdkn1ba)


Basic Information

Item Value
gene id XLOC_028716
gene name cdkn1ba
gene type coding
species zebrafish (Danio rerio)
category of species model fish

Chromosome Information

Item Value
chromosome id NC_007115.7
NCBI id CM002888.2
chromosome length 78093715
location 18592743 ~ 18595525 (-)
genome version GRCz11_2017_zebrafish_Genome

Sequence

>TCONS_00055673
GTTTTATTTGCGATCGCCATATTGGGTGCTCGAACGACTTGTCTGTTTTCCTCGGAATTACTACGACGGGGATCGCCGTTTTCATGACTCGTTCGCCGCTCGCGCGCGTTCGCCTTTCCGCGTTTGTTATGCGTGCGCCCTGCGCCTCGCTCCGCGTTCTCGGGAGGGATTGCTCTTAGTTACGCCGCGTCTGCGATTCTCGGACAAACTTTTCACGTGCGAAATGTCAAAAGTGCGCGTCTCCAATGGAAGTCCGACGCTGGAGCGAGTGGACCCCAGGCAGGCGGATCACGGCAAGCCGCCTGTCTGCCGAAGTCTCTTCGGCGCCGTGGACCGCCAAGAGTTCGCCAAGGATGTACGGGAGCAAATGCGGGAGATCGAGAGAGCGTCCGCGGAAAAGTGGAATTACGACTTCGCCGAAAACCGACCGCTCGCGCCGGGCGACTACGAGTGGCAGGAGGTGGACGCCGACGAAGTGCCGGACTTTTACACCAGACCCCCTCGCGTAAAACGGCCCTCTTCGGCCGGGACTGTGGATCATAACGGGAACCACGATTATTTCTTGACGGCTCCCTCTCCGTCCCCGGAGAGCGGAGCGGGGAACTCCGAACGCGCGGACGCCGGGAACCGCTCGCTCAGCACGCCGAGGAAACGACCGTCGACGGAAGATCAGGATGATCTTCGCCGAAGCAAAAGACCCAGCGTCCACGCGAGCGAGGCCGACCCCTGTCCGGACGCGACGAGCTCGCTCGAGCGCGCTCCCTGCGAACCGGACCCCAAAACGTAAAGgagATACGCCGAGAAGCCCGCCCTCACCATCGACTACTTCGCCAGCCTTGCCAAGTAAACGGGGACAGACGGCGCTTCCAAAATACAAATCGAGCCTCGGAGGGGCTGAATAAGCACTGAATTTTTACACTAAACTTTTGGCACTCGACAGATTTTATATTTGCCTCAAAAGCAGACGATGTAGCAGTATGCGATTGGAGTTGCTTCGTTTCTTCTTTTACTacctatgtatatatatatatatattttttttctttttataatgtaGCACGTTTTCGTTTCATGTTCATGTCAAAGCAAAACGCGATCCTTCACTAATCCACCGCGCTTCACTTTAAGAATTGCTGCGCGGTTTTTCAAACGCATCTCCCGAACGAACCGTTTTAAAGTAGCCCACATATccctatggatggatggatagatagaccgtctgtcagacacacacacacacacacacacacacacacacacgcacacacacattaggAGCATCTTTCCACTGCTCTCGATTTTGCCTGCCTCACAAAATACACCTTAAGTGCTCAACGCTCGCCCTTGTTAAAGTTGCACAAATGTCATCGTCTAAACCGTTACTTTTCTTCTCACCTCATGTGACCTAACTACATTAAACCGCTTCGATAATTACATTAACGCGACTCATGTTTATTGGTACTTAAGCTCATTTTCTTTGGTttttcacactcaaacacacctTGGTCATGAGAACTGTGGCTCTTAGTGTGCTGTTAAACGTTTCGCgcttttttacagtattattatattatccttGGGTTCTTCCactaattttactttatttatttcgcTTCATTAGCATCCTCGTATCAATTTCTCATTAACTACAAATCCTACTGAGTACACGATACAACAGAGCAACTGTATTGATCCCTtgattattttttgccttttttacGTTCGTTGGCGTGTAGCTTTacgtttctatatatatatatatatatatatatatatatatatatatatatatatatatatatatatatatatatatatatatatatatatatatatatatagttagtaCTTTCTCTTAACACTGGGCCATACGTTTAACAACAACATTAGTCCGTGAAGCCGCTTCTTTGCAACGATATATCTGGCTTTCGTGTTGAACATGACATGGCACTATGATTGCAAATCTCTATGAAAACTCAATTAAGACGTTACACTGCGCCTGTGTAAAACATTCAAGTGTACATGTGCTCGTAAACAAAACTAAAAGGATAAAAAAAACACTGAGGAAATTATACTAACTTATTTATGTCAAGCTTTTTCTTGTTTATGACTATCCAAAGTGGCATTTGTGCATTTTCTCTTATTACTTCTTTTTGTAATTttccttttctccttttttatcCATTTGTGCAAGGTTGCATACTGAGCCTTTTAAGAAATGATGTGGACTGTGTATTGCTTTATAAATGAAACGATTAAACCATCATGACATTGACCCTT
>TCONS_00055674
GCGTCCGCGGAAAAGTGGAATTACGACTTCGCCGAAAACCGACCGCTCGCGCCGGGCGACTACGAGTGGCAGGAGGTGGACGCCGACGAAGTGCCGGACTTTTACACCAGACCCCCTCGCGTAAAACGGCCCTCTTCGGCCGGGACTGTGGATCATAACGGGAACCACGATTATTTCTTGACGGCTCCCTCTCCGTCCCCGGAGAGCGGAGCGGGGAACTCCGAACGCGCGGACGCCGGGAACCGCTCGCTCAGCACGCCGAGGAAACGACCGTCGACGGAAGATCAGGGTAAATGTTTCGCGGCTCGGACGTCTCTCCGTTCGCGAAAGCGACCTTTTCTAACACCATCTACGTTCTCCCAATAGATGATCTTCGCCGAAGCAAAAGACCCAGCGTCCACGCGAGCGAGGCCGACCCCTGTCCGGACGCGACGAGCTCGCTCGAGCGCGCTCCCTGCGAACCGGACCCCAAAACGTAAAGgagATACGCCGAGAAGCCCGCCCTCACCATCGACTACTTCGCCAGCCTTGCCAAGTAAACGGGGACAGACGGCGCTTCCAAAATACAAATCGAGCCTCGGAGGGGCTGAATAAGCACTGAATTTTTACACTAAACTTTTGGCACTCGACAGATTTTATATTTGCCTCAAAAGCAGACGATGTAGCAGTATGCGATTGGAGTTGCTTCGTTTCTTCTTTTACTacctatgtatatatatatatatattttttttctttttataatgtaGCACGTTTTCGTTTCATGTTCATGTCAAAGCAAAACGCGATCCTTCACTAATCCACCGCGCTTCACTTTAAGAATTGCTGCGCGGTTTTTCAAACGCATCTCCCGAACGAACCGTTTTAAAGTAGCCCACATATccc

Function

symbol description
cdkn1ba Predicted to enable chaperone binding activity and cyclin-dependent protein serine/threonine kinase inhibitor activity. Predicted to be involved in G1/S transition of mitotic cell cycle; negative regulation of cell cycle; and negative regulation of cell population proliferation. Predicted to act upstream of or within regulation of cell cycle and regulation of cell population proliferation. Predicted to be located in endosome. Predicted to be active in cytoplasm and nucleus. Is expressed in otic vesicle. Human ortholog(s) of this gene implicated in acute myeloid leukemia; breast cancer; multiple endocrine neoplasia type 4; and myelodysplastic syndrome. Orthologous to human CDKN1B (cyclin dependent kinase inhibitor 1B).

GO:

id name namespace
GO:0045736 negative regulation of cyclin-dependent protein serine/threonine kinase activity biological_process
GO:0042127 regulation of cell population proliferation biological_process
GO:0000082 G1/S transition of mitotic cell cycle biological_process
GO:0007050 cell cycle arrest biological_process
GO:0008285 negative regulation of cell population proliferation biological_process
GO:0045930 negative regulation of mitotic cell cycle biological_process
GO:0042326 negative regulation of phosphorylation biological_process
GO:0005634 nucleus cellular_component
GO:0005737 cytoplasm cellular_component
GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity molecular_function
GO:0051087 chaperone binding molecular_function

KEGG: NA

ZFIN:

id description
ZDB-GENE-040812-3 Predicted to enable chaperone binding activity and cyclin-dependent protein serine/threonine kinase inhibitor activity. Predicted to be involved in G1/S transition of mitotic cell cycle; negative regulation of cell cycle; and negative regulation of cell population proliferation. Predicted to act upstream of or within regulation of cell cycle and regulation of cell population proliferation. Predicted to be located in endosome. Predicted to be active in cytoplasm and nucleus. Is expressed in otic vesicle. Human ortholog(s) of this gene implicated in acute myeloid leukemia; breast cancer; multiple endocrine neoplasia type 4; and myelodysplastic syndrome. Orthologous to human CDKN1B (cyclin dependent kinase inhibitor 1B).

Ensembl:

ensembl_id ENSDARG00000029018

RNA

RNA id representative length rna type GC content exon number start site end site
TCONS_00055673 False 2280 mRNA 0.45 3 18592743 18595525
TCONS_00055674 True 885 processed_transcript 0.53 2 18593830 18595140

Neighbor

gene id symbol gene type direction distance location
XLOC_028715 rint1 coding downstream 80193 18500012 ~ 18512550 (-)
XLOC_028714 sco2 coding downstream 137263 18453702 ~ 18455480 (-)
XLOC_028713 socs2 coding downstream 155844 18432182 ~ 18436899 (-)
XLOC_028712 cradd coding downstream 176177 18383253 ~ 18416566 (-)
XLOC_028711 plxnc1 coding downstream 276831 18281954 ~ 18315912 (-)
XLOC_028717 CDPF1 coding upstream 1637 18597162 ~ 18606573 (-)
XLOC_028718 pparaa coding upstream 14014 18609539 ~ 18635005 (-)
XLOC_028719 dre-let-7b coding upstream 57623 18653148 ~ 18653241 (-)
XLOC_028720 dre-let-7a-3 coding upstream 58630 18654155 ~ 18654261 (-)
XLOC_028721 NA coding upstream 59157 18654682 ~ 18679692 (-)
XLOC_028709 BX901882.1 non-coding downstream 403223 18189406 ~ 18189520 (-)
XLOC_028707 NA non-coding downstream 709813 17875071 ~ 17882930 (-)
XLOC_028702 BX890572.1 non-coding downstream 854931 17736443 ~ 17737812 (-)
XLOC_028696 NA non-coding downstream 963299 17571295 ~ 17629444 (-)
XLOC_028690 NA non-coding downstream 1376520 17113379 ~ 17216223 (-)
XLOC_028722 NA non-coding upstream 117238 18712763 ~ 18714926 (-)
XLOC_028730 dre-mir-129-1 non-coding upstream 451941 19047466 ~ 19047555 (-)

Expression


Co-expression Network