XLOC_028734 (hgfa)



Basic Information


Item Value
gene id XLOC_028734
gene name hgfa
gene type coding
species zebrafish (Danio rerio)
category of species model fish

Chromosome Information


Item Value
chromosome id NC_007115.7
NCBI id CM002888.2
chromosome length 78093715
location 19710657 ~ 19742303 (-)
genome version GRCz11_2017_zebrafish_Genome

Sequence


>TCONS_00055702
AGTGTGTgcttgagaaagagagagagagtgagagagcagTCGCTGCGGTTTGATCCTGTTCATCCTTcacaccagcagcagcagcagcatcaacTCGGACTTTATAGACTCTCCATCCCACAGCCTGGAATATCAAACCGAGAAACATGAGATCGGACATTATGTGGATGTATCAAGCTCTTCTCTTTGTCGTACTGACCGTGAATGTGGATTGCAGAAAACAGACATTGCAGAGGTATCAGAAAAGTGAAAACAGCCGACTGCTTTGTACAGACTGTCCAGAATCCCCTCGAATTAGGAACCTGTCGCTGGAGGAATGCGCACGCAAATGTAGCAAGAGCAAGAAGTCCTGCAGGGCATTCTACTTTGACCACATAAACAGGAAATGTCACTTTCTTCCTTTTGACCGTTTCTCCGAAGGCGCGAAGAGAGAGCGAAAACCCAGTTGTGACCTTTACGAGAAGAAagACTATGTGAGGGAGTGCATCATTGGGTCAGGTGTCAACTACAAGGGGAGAAGGTCATTCACAAAGACTGGAATTACGTGCCAATCCTGGAATATGTCCGTCCCACATGAGCACAATTTTAAGCCTACCAGACACAAAAAGTCTGACCTACGTCAGAACTTTTGCCGAAATCCAGACAATGATCCAAATGGGCCCTGGTGCTTCACTGAACTCACTGAGACCCGGCACCAGGATTGTGGACTGCCTCAGTGTTCAGATGTGGAGTGTATGAAATGTAATGGGGAAACCTACAGAGGGCCCATGGATCATACAGAGAGTGGGAAAGAGTGCCAGAGATGGGACTCGCAGAAACCTCATAAACACACCTACCAGCCTCACAGGCATGTAGGTAAAGGTCTGGATGACAACTTCTGCCGCAATCCCAATAATGATGTTCGTCCGTGGTGTTACACGATGGACAAAAACACCCCTTGGGAGTACTGTAACATCAGTGTGTGTGACTCAGATAGCGATGTGGAAGTGGAGGTGACCAGCTCTTGTTTTCGGGGTCAAGGAGAGGGCTACAGGGGTACAGTCAACGTGACCCCTGCAGGTGTGACCTGTCAACGCTGGGACGCTCTCTCTCCTCACATCCATTCATACACTCCGCACAACTATAAATGCAAGGATCTGAGGGAGAACTATTGCAGAAATCCTGATGGCTCTGAAATTCCCTGGTGTTTCACCACAGACGCAAAAGTGCGCAAAGCTTTCTGTACCAACATTCCCAGATGCGAATCAGAGAGCTCTGACAGCACAGAATGTTATGAAGACAACGGAGAGAGTTATCGTGGCAATTTGTCGAAAACGAGATCTGGTATTCCTTGCGGACTCTGGTCTGACCACACATTCAGgAGAGACACCCGGTCAGCGAAGGCCAGCGCGGGTTTAGAGTTGAACTTGTGCAGGAATCCAGACAGAGATAAGCACGGGCCGTGGTGCTACACGTCCAACTCCTCCATTCCCTGGGACTACTGCGGACTGGAGCGCTgTAAATCAATGTCATCGGATGACCATCAAATGAGTGGAGGACCAAAACCATCTTGCTTTATACATAAAACCACACGGATTGTTGGGGGAATGCGAGTGCAGCGGGCAGAGGATGGAAGTTGGGTGGTCAGCATTCAGAAAGGGAACAGACACTGGTGCGGTGGCTCTCTCATCAGAGAAGAATGGGTTCTCACTGATCAACAGTGCTTCTCCACCTGCGTTCCTGACCTCTCCGAGTACACCGTGCAGGTGGGGCTTCTTCATCTCAATGCATCCGCCGGCACGCAGGCTCTCCGAATCGCACATGTGGTCTGCGGGCCCGAGGGATCCAACTTGGCCCTGCTCAAACTCACAACGCCTGCCCCTCTCTCTGAGCATGTGCGAACTGTTCAGCTTCCGGTCGCTGGCTGTGCTGTTGCAGAAGGCACTCTGTGTCTCATGTATGGATGGGGAGACACTAAAGGCACAGGACACGAGGGCAGTCTGAAGATGGTGGGACTTCCAATTGTCAGCAACAAGAGGTGTTCACAAAGCCACAATGGCATCCTGCCCATCACCGAGACCAAAATCTGTGCTGGAGGCAAGAGAGATCAGGGCGTTTGTGAGAAAGACTACGGTGGCCCTTTGGTGTGCCAGGAAGGAGAGAGCAAAGTGATAGTTGGCGTCAGCATCAACGGCCGTGGTTGTGCAGTAGCGAGACGTCCTGCTGTCTTCGTCAACGTGGCCTTCTACTCTGAATGGATCCGCAAGGTCTTCAAGTACTATTCAGACATGGAAATAAGTTACTAGATCTCCATATGTGGTAAATAAGACTAAATGGTTTAGCATCTACATCGTGAAGGACGATTAGCATTCAAACATTTTGGAGGCTAAAGTTTGCTTTGGTGTATAGATGTTGCATAATAACCACTGGTACAGAAAAGGTGCAAGATTATCGATGTGTTTGTGAACAAATGAAGGAAATGACAACATCGGAACTTTTTTTAGGAGATTGTTGTGGCTGGTGAGAAATCAAGGACAGATGATGAATGAACTGTGGCGTTCATCCATGTGAAAGCAGATGTTGTTCTTAATGTCATTCCCTGGAATTACTTGAAGACGACATTTtcggtttttgttttttgcagctTGCTGAATTTTACAGTGCTTTTAAGGACTAGATTCAGTATTACTGTTTCCAAAACACCTTTTTTAACATTGGTTACTAAAGAAATCAGATTGCAAACCGCAATATGCGCTGCCGTTGGTTTATAAACGCCTATCTGGGGCATTATCAGACACTTCCAGAATGTTTCGGTGATGGTCTAACGTTTCGCACCTTGCCTTACTCCAGTTTGGAGAGATTTTGTGGCTCCTTTGgggctgttttctttttttatgtactgCACTCTAAAGAGTGTGCTAAAATGTCACTCTGTAGGTCTTATAGATCTGAAATTACAAACATTTGGAGGTCTTTTCTTTCACATggtgtaatttatatatatatctgtcgAAATTTTATACGCGGTATTTATTTATACCTTTTATAGATGGACCCGAGCCGTGGCATTTCATCCTCCAGTAGTGTTTATTGTGTTTAATCTGGCGTGCAGATTTGAATCATAacatttgtaaacaaaacaaacgGATGATATGTCTTTGAAGGAAAATATTGGGTCATAACAGAGCGCTTCGACTCAAAGACGACTCCCTGAAGGTTTAAAAGCCACACATGCGGAGGGTCTTTTAAGAACAAGTTTAGCCATGAGTGCAAAGATACTTCATCAAACTGCAGTACTGAATAGAGTAACGCACAGGCAGGGTTTTTACAAGGTTTTTACAAGTACAAGAATGTATTTTGATTTAAATGTTGTGTTCGCTGTGTGTATACAGAAAAGTGCCTGTTTTTGTGGCGTTTTATTGATTTTCGCAGTTAATGTAATTCCTCTTTGCGCTGCTGCCCTCATTGGTCGTTTTATTGAATATCTAGGCTGCTgttatttttgacattatttttaggactgttttgtattttcaacttttaaaaatgtatgtaaatacatctgtgacattttgttttttttttatttgtaaataattaaatcgtt
>TCONS_00055703
GGTAGTGTGTgcttgagaaagagagagagagtgagagagcagTCGCTGCGGTTTGATCCTGTTCATCCTTcacaccagcagcagcagcagcatcaacTCGGACTTTATAGACTCTCCATCCCACAGCCTGGAATATCAAACCGAGAAACATGAGATCGGACATTATGTGGATGTATCAAGCTCTTCTCTTTGTCGTACTGACCGTGAATGTGGATTGCAGAAAACAGACATTGCAGAGGTATCAGAAAAGTGAAAACAGCCGACTGCTTTGTACAGACTGTCCAGAATCCCCTCGAATTAGGAACCTGTCGCTGGAGGAATGCGCACGCAAATGTAGCAAGAGCAAGAAGTCCTGCAGGGCATTCTACTTTGACCACATAAACAGGAAATGTCACTTTCTTCCTTTTGACCGTTTCTCCGAAGGCGCGAAGAGAGAGCGAAAACCCAGTTGTGACCTTTACGAGAAGAAagACTATGTGAGGGAGTGCATCATTGGGTCAGGTGTCAACTACAAGGGGAGAAGGTCATTCACAAAGACTGGAATTACGTGCCAATCCTGGAATATGTCCGTCCCACATGAGCACAATTTTAAGCCTACCAGACACAAAAAGTCTGACCTACGTCAGAACTTTTGCCGAAATCCAGACAATGATCCAAATGGGCCCTGGTGCTTCACTGAACTCACTGAGACCCGGCACCAGGATTGTGGACTGCCTCAGTGTTCAGATGTGGAGTGTATGAAATGTAATGGGGAAACCTACAGAGGGCCCATGGATCATACAGAGAGTGGGAAAGAGTGCCAGAGATGGGACTCGCAGAAACCTCATAAACACACCTACCAGCCTCACAGGCATGTAGGTAAAGGTCTGGATGACAACTTCTGCCGCAATCCCAATAATGATGTTCGTCCGTGGTGTTACACGATGGACAAAAACACCCCTTGGGAGTACTGTAACATCAGTGTGTGTGACTCAGATAGCGATGTGGAAGTGGAGGTGACCAGCTCTTGTTTTCGGGGTCAAGGAGAGGGCTACAGGGGTACAGTCAACGTGACCCCTGCAGGTGTGACCTGTCAACGCTGGGACGCTCTCTCTCCTCACATCCATTCATACACTCCGCACAACTATAAATGCAAGGATCTGAGGGAGAACTATTGCAGAAATCCTGATGGCTCTGAAATTCCCTGGTGTTTCACCACAGACGCAAAAGTGCGCAAAGCTTTCTGTACCAACATTCCCAGATGCGAATCAGAGAGCTCTGACAGCACAGAATGTTATGAAGACAACGGAGAGAGTTATCGTGGCAATTTGTCGAAAACGAGATCTGGTATTCCTTGCGGACTCTGGTCTGACCACACATTCAGgAGAGACACCCGGTCAGCGAAGGCCAGCGCGGGTTTAGAGTTGAACTTGTGCAGGAATCCAGACAGAGATAAGCACGGGCCGTGGTGCTACACGTCCAACTCCTCCATTCCCTGGGACTACTGCGGACTGGAGCGCTGTGGAGGACCAAAACCATCTTGCTTTATACATAAAACCACACGGATTGTTGGGGGAATGCGAGTGCAGCGGGCAGAGGATGGAAGTTGGGTGGTCAGCATTCAGAAAGGGAACAGACACTGGTGCGGTGGCTCTCTCATCAGAGAAGAATGGGTTCTCACTGATCAACAGTGCTTCTCCACCTGCGTTCCTGACCTCTCCGAGTACACCGTGCAGGTGGGGCTTCTTCATCTCAATGCATCCGCCGGCACGCAGGCTCTCCGAATCGCACATGTGGTCTGCGGGCCCGAGGGATCCAACTTGGCCCTGCTCAAACTCACAACGCCTGCCCCTCTCTCTGAGCATGTGCGAACTGTTCAGCTTCCGGTCGCTGGCTGTGCTGTTGCAGAAGGCACTCTGTGTCTCATGTATGGATGGGGAGACACTAAAGGACACGAGGGCAGTCTGAAGATGGTGGGACTTCCAATTGTCAGCAACAAGAGGTGTTCACAAAGCCACAATGGCATCCTGCCCATCACCGAGACCAAAATCTGTGCTGGAGGCAAGAGAGATCAGGGCGTTTGTGAGAAAGACTACGGTGGCCCTTTGGTGTGCCAGGAAGGAGAGAGCAAAGTGATAGTTGGCGTCAGCATCAACGGCCGTGGTTGTGCAGTAGCGAGACGTCCTGCTGTCTTCGTCAACGTGGCCTTCTACTCTGAATGGATCCGCAAGGTCTTCAAGTACTATTCAGACATGGAAATAAGTTACTAG

Function


symbol description
hgfa Predicted to enable serine-type endopeptidase activity. Acts upstream of or within cerebellar granule cell differentiation and neuron migration. Is expressed in several structures, including DEL; adaxial cell; axis; endodermal cell; and forebrain neural rod. Human ortholog(s) of this gene implicated in several diseases, including artery disease (multiple); autosomal recessive nonsyndromic deafness 39; eye disease (multiple); neuropathy (multiple); and scleroderma (multiple). Orthologous to human HGF (hepatocyte growth factor).

GO:

id name namespace
GO:0021549 cerebellum development biological_process
GO:0001764 neuron migration biological_process
GO:0021587 cerebellum morphogenesis biological_process
GO:0021953 central nervous system neuron differentiation biological_process
GO:0006508 proteolysis biological_process
GO:0021707 cerebellar granule cell differentiation biological_process
GO:0004252 serine-type endopeptidase activity molecular_function
GO:0008083 growth factor activity molecular_function

KEGG: NA

ZFIN:

id description
ZDB-GENE-041014-2 Predicted to enable serine-type endopeptidase activity. Acts upstream of or within cerebellar granule cell differentiation and neuron migration. Is expressed in several structures, including DEL; adaxial cell; axis; endodermal cell; and forebrain neural rod. Human ortholog(s) of this gene implicated in several diseases, including artery disease (multiple); autosomal recessive nonsyndromic deafness 39; eye disease (multiple); neuropathy (multiple); and scleroderma (multiple). Orthologous to human HGF (hepatocyte growth factor).

Ensembl:

ensembl_id ENSDARG00000045544

RNA


RNA id representative length rna type GC content exon number start site end site
TCONS_00055702 False 3586 mRNA 0.45 18 19710657 19742300
TCONS_00055703 True 2249 mRNA 0.51 17 19711958 19742303

Neighbor


gene id symbol gene type direction distance location
XLOC_028732 snd1 coding downstream 16549 19396945 ~ 19694108 (-)
XLOC_028733 NA coding downstream 171567 19534461 ~ 19539090 (-)
XLOC_028731 NA coding downstream 340872 19268385 ~ 19369785 (-)
XLOC_028730 dre-mir-129-1 coding downstream 663102 19047466 ~ 19047555 (-)
XLOC_028729 lepb coding downstream 676852 19031768 ~ 19033805 (-)
XLOC_028735 cacna2d1a coding upstream 26376 19768679 ~ 19884440 (-)
XLOC_028736 NA coding upstream 157712 19900015 ~ 19901133 (-)
XLOC_028737 BX323820.1 coding upstream 161481 19903784 ~ 19921410 (-)
XLOC_028738 drd4-rs coding upstream 203991 19946294 ~ 20027571 (-)
XLOC_028739 BX855618.1 coding upstream 295218 20037521 ~ 20039635 (-)
XLOC_028722 NA non-coding downstream 995731 18712763 ~ 18714926 (-)
XLOC_028721 NA non-coding downstream 1030965 18654682 ~ 18679692 (-)
XLOC_028741 NA non-coding upstream 302564 20044867 ~ 20047884 (-)
XLOC_028746 NA non-coding upstream 380610 20122913 ~ 20124058 (-)
XLOC_028756 BX248410.1 non-coding upstream 653746 20396049 ~ 20396170 (-)
XLOC_028761 NA non-coding upstream 1849941 21592244 ~ 21628998 (-)

Expression



Co-expression Network