XLOC_028796 (pfkfb3)


Basic Information

Item Value
gene id XLOC_028796
gene name pfkfb3
gene type coding
species zebrafish (Danio rerio)
category of species model fish

Chromosome Information

Item Value
chromosome id NC_007115.7
NCBI id CM002888.2
chromosome length 78093715
location 25472505 ~ 25485404 (-)
genome version GRCz11_2017_zebrafish_Genome

Sequence

>TCONS_00055800
ATGCCAAGGGAACTAACCCAAAACAGGATCCAAAAAATCTGGATTCCCTCTAAGGATGACAAGCCTTCAATGCCCCGCGCACCACGTGGAGGCCCTCATTTGGCAAACCCTCCAACAGTGATTGTGATGGTCGGACTTCCTGCTCGGGGCAAGACTTATATGTCCAGAAAACTCACTCGCTACCTCAACTGGATTGGAATCCCCACTAAAGTCTTTAATGTTGGCGAGTATCGTCGTGAAGCAGTGAAACACTACAGCTCCTATGATTTCTTCAAATCAGACAATGAGGATGCTGTAAAAATCAGACAGCAGTGTGCCCTGGCCGCTCTTAGAGATGTCAAGAATTACCTCACTGAAGAGGACGGTCAAGTGGCTGTTTTTGATGCAACAAACACAACCAGAGATCGACGAGATATGATCTTGGAGTTTGGTGCAGAAAATGGCTTCAAGATTTTCTTTATTGAGTCCGTGTGTGAGGACCCAAACGTTATCGCCTGTAATATCCTGGAAGTTAAGGTGTCATGTCCAGACTACCAAGATTGCAACAAGACAGATGCCATGGAGGACTTCAAGAAAAGAATTGAATGTTACAGAATGAACTATCAGCCTCTTGACCCTGACCAGTATGACAGAAGCTTGTCCTTCATCAAAGTGATTGATGTCGGTCGCAGATTCCTGGTCAACCGCATTCAAGACCACATCCAGAGTCGCATCGTGTACTATTTGATGAATATCCACGTGCAGCCGCGCTCCATTTATTTATGCCGCCATGGCGAAAGCCAGCACAACCTCCAGGGTAGACTGGGAGGAGATTCTGGTCTGTCTACACGAGGACGAAAGTTCGCAGGTGCTCTTGCTAAGTTTGTGGAGGAGCAGAATTTGAAGGATTTGAAGGTTTGGACCAGCCAGCTGAAGCGTAGTATCCAAACAGCAGAGGCTCTCAATGTGCCGTACGAACAGTGGAAAGCCCTCAATGAGATTGATGCCGGTGTGTGTGAGGAGATGACCTATGAAGAAGTCAGGGAGAGGTTTCCCGAGGAGTTTTCTCTTAGAGATCAGGACAAATACTACTACCGCTACCCTTCCGGAGAGTCATATCAGGATTTGGTTCAGCGTGTGGAGCCGGTGATTATGGAAATGGAGCGACAGGAGAATGTTCTGGTCATCTGTCACCAGGCGGTGATTCGATGCCTACTCGCCTATTTCCTTGACAAAAGTGCAGaTGAGATGCCATATCTGAAGTGTCCTCTCCACACCGTACTCAAGCTGACCCCAGTGGCTTACGGATGCAAAGTGGAATCTATCTCTCTGAATGTGGAGGCAgtgaacacacacagagaaagaccAGAGGAGGTGAAGCGAGGCCCAAGCACTCTGATCAGGAGAAACAGCGTGACTCCTCTCACCAGCCATGAACCTTTTAAGAAGCCTCGTATCGATGGTCTGGATGAGCCAATCATCAGAGAAGTGATGCCGGCTCAACTTGCTCTCTGCTCAGCCTCACACACCACACTGGCTCTGTCCACACAGAACCTGAAGAAATGCTGTATAGAGTGCCATGAAGCCCCTCAGCTTTGCCTGTGAGATTATTCGGCTGTAAAGCTTTACTCGACGTGGAAGAGTTTCCTGTCAAGCTGCTTCCTCTCCTTTTCccacataaaaaaagaaatggacCCTTGGGTTTTTCCTATTTGTAAGGAATGCACATACTATGTGGTTTGTACTAGTAAGGAGTTTTTGGATATAAAGTGTATCCAGAGCACAGTGACAGGGATTACCAATTTATAACCCCCCACCTCCCCTGACATTTTTGGACACTATTCCCTGTTTATATAACAGGATACCACTTGTTAATATTTGAATTCTGGTCTCATCCAGATGTGTAACACTGATGGTAAGAATAAGCCCTGTGATTTCGAGAAGACGACGCTAAAAAACAGACCAAAGATCACCCACGGATGTTAGTGGGCTGATTTGTGTCCATTCTGCACTCGCTATCATATGCTGCAAACTAAATTGCACATTCTAATTgcacatttagatcatttgcatttgtttgtctTCATTTTTTTTGAAGGGCAATAACGAATATTACAAATTTCGTTCTTTTTAATGCTGCTGGCTGTTTTCAAGGCTGTTTAAAAGTTCTCATGTCGTCTGCTGCAGTTTCACGTGATTTGTGTTATGATATggattgtgagtgtgtgtttttatgtgtgtaaTTTGTGTGCTTCGGAGACCTGATGACAAGGTCAATGCGTAAGGTTATGAAAACAGGGTGTTTTATCGAGTGTTTGGATGGGACGAAGTGAAACAGTgtttatatttgttgtttatatCTAATGTGTTTTATGGCGTGATAAATATCAGATACAATTTTTTTatactgttcatttattaattcccTAGAGTGCCTAGTGCTTGAGCTATCAGGCCAGAGCTGCTTTTTGTATTGTAATGAGAAttctatacagtatatatataaaatttatatatatatataaaaaatgtaacatttgaaGTAGCTTTAGCTTTATCATTTCAATTTCTTGTCACAGCCACAAGAATTTAAACTAGCATTTGATATAATATGTATGTACAGATTTATCCTCTTAACcaaatgtttacaatttaaatatatagTAGATTTTTGTAGAAAGGGAGTGAAATTTGAAGAACCGGCTTTAACTGTAAATGGATGTTTCTGAGAAGAAGTCTAGTTGTTGCTttgtaatataaaacaattaagttcatCACACGACTAGGTGCAATCTTGTATATTGGCTCTTAACTGTAATTCATGTTTGCTTCTGATACTTGAACCTTATTTTGTAATATCTTtcctttttttgttaaaataatatttatttatttgtactagTCTGTGTTTCATGCACTTTGTTCATAACTGAGATTCTAGAGCATATCAGCAAATACAATTGTTTCTTTCTGAAGAAAGTGAATTATCTATATGCGATTACCGAATCAATAAAGAGTCTAAAAGAGAATGTGtgggtttttgtttttgtaaaaaaaaaaaataataaataataataataaaaaatttgtttctttgtcatTTTTCCCTTTGAGTGTAAAGTTACATTAAGCCAGagatgtccaaactctgtcctggagggctgatgtcctgcatagtttagctccaattttcttcaacacaccttccTGGATGTTCTAGTACAGGTgtggtcaaccctgttcctggagagccaccttcctgcagatttcagttgcaacccatatcaaacacatctgcctgtaattatcacgtggtgttcaggtcctaattaattggttcaggtgtgtttgatatgggtagcaactgaaatctgcaggaaggtcgctctccaggaacagggttggccacccctgttttagtatacctagaaagagcttgattagcttgttcaggtgtgtttaattggggttggaactaaaatatgcaggacactggccctcctggacagagtttggacaaccctgcaTTAAGCTAAACGGGcgaga
>TCONS_00055801
GGGAAGCGAATAGACGAGGTGTACGAGATATAACCACCGAAAATCGTCGAACAGCTCAAAAAGAAAATCGTTAATACACAGAAGAGCAGTCTTAactaaaaggttttgttttactAAACAAAACGTGGAATTCCAAAAGCCTCTGTGACCTGCTGCGGTTATCTTGCTGATTGTTCCACATCTTTAAGGAATGCCAAGGGAACTAACCCAAAACAGGATCCAAAAAATCTGGATTCCCTCTAAGGATGACAAGCCTTCAATGCCCCGCGCACCACGTGGAGGCCCTCATTTGGCAAACCCTCCAACAGTGATTGTGATGGTCGGACTTCCTGCTCGGGGCAAGACTTATATGTCCAGAAAACTCACTCGCTACCTCAACTGGATTGGAATCCCCACTAAAGTCTTTAATGTTGGCGAGTATCGTCGTGAAGCAGTGAAACACTACAGCTCCTATGATTTCTTCAAATCAGACAATGAGGATGCTGTAAAAATCAGACAGCAGTGTGCCCTGGCCGCTCTTAGAGATGTCAAGAATTACCTCACTGAAGAGGACGGTCAAGTGGCTGTTTTTGATGCAACAAACACAACCAGAGATCGACGAGATATGATCTTGGAGTTTGGTGCAGAAAATGGCTTCAAGATTTTCTTTATTGAGTCCGTGTGTGAGGACCCAAACGTTATCGCCTGTAATATCCTGGAAGTTAAGGTGTCATGTCCAGACTACCAAGATTGCAACAAGACAGATGCCATGGAGGACTTCAAGAAAAGAATTGAATGTTACAGAATGAACTATCAGCCTCTTGACCCTGACCAGTATGACAGAAGCTTGTCCTTCATCAAAGTGATTGATGTCGGTCGCAGATTCCTGGTCAACCGCATTCAAGACCACATCCAGAGTCGCATCGTGTACTATTTGATGAATATCCACGTGCAGCCGCGCTCCATTTATTTATGCCGCCATGGCGAAAGCCAGCACAACCTCCAGGGTAGACTGGGAGGAGATTCTGGTCTGTCTACACGAGGACGAAAGTTCGCAGGTGCTCTTGCTAAGTTTGTGGAGGAGCAGAATTTGAAGGATTTGAAGGTTTGGACCAGCCAGCTGAAGCGTAGTATCCAAACAGCAGAGGCTCTCAATGTGCCGTACGAACAGTGGAAAGCCCTCAATGAGATTGATGCCGGTGTGTGTGAGGAGATGACCTATGAAGAAGTCAGGGAGAGGTTTCCCGAGGAGTTTTCTCTTAGAGATCAGGACAAATACTACTACCGCTACCCTTCCGGAGAGTCATATCAGGATTTGGTTCAGCGTGTGGAGCCGGTGATTATGGAAATGGAGCGACAGGAGAATGTTCTGGTCATCTGTCACCAGGCGGTGATTCGATGCCTACTCGCCTATTTCCTTGACAAAAGTGCAGaTGAGATGCCATATCTGAAGTGTCCTCTCCACACCGTACTCAAGCTGACCCCAGTGGCTTACGGATGCAAAGTGGAATCTATCTCTCTGAATGTGGAGGCAgtgaacacacacagagaaagaccAGAGGAGGTGAAGCGAGGCCCAAGCACTCTGATCAGGAGAAACAGCGTGACTCCTCTCACCAGCCATGAACCTTTTAAGAAGCCTCGTATCGATGGTCTGGATGAGCCAATCATCAGAGAAGTGATGCCGGCTCAACTTGCTCTCTGCTCAGCCTCACACACCACACTGGCTCTGTCCACACAGAACTGGCTTAGCGAAGCTTGTCTACGCTCTTTTTTACATTACCTACAAGTGGTGTCAGTCCTGCTCTTTCAGAGAACCTGAAGAAATGCTGTATAGAGTGCCATGAAGCCCCTCAGCTTTGCCTGTGAGATTATTCGGCTGTAAAGCTTTACTCGACGTGGAAGAGTTTCCTGTCAAGCTGCTTCCTCTCCTTTTCccacataaaaaaagaaatggacCCTTGGGTTTTTCCTATTTGTAAGGAATGCACATACTATGTGGTTTGTACTAGTAAGGAGTTTTTGGATATAAAGTGTATCCAGAGCACAGTGACAGGGATTACCAATTTATAACCCCCCACCTCCCCTGACATTTTTGGACACTATTCCCTGTTTATATAACAGGATACCACTTGTTAATATTTGAATTCTGGTCTCATCCAGATGTGTAACACTGATGGTAAGAATAAGCCCTGTGATTTCGAGAAGACGACGCTAAAAAACAGACCAAAGATCACCCACGGATGTTAGTGGGCTGATTTGTGTCCATTCTGCACTCGCTATCATATGCTGCAAACTAAATTGCACATTCTAATTgcacatttagatcatttgcatttgtttgtctTCATTTTTTTTGAAGGGCAATAACGAATATTACAAATTTCGTTCTTTTTAATGCTGCTGGCTGTTTTCAAGGCTGTTTAAAAGTTCTCATGTCGTCTGCTGCAGTTTCACGTGATTTGTGTTATGATATggattgtgagtgtgtgtttttatgtgtgtaaTTTGTGTGCTTCGGAGACCTGATGACAAGGTCAATGCGTAAGGTTATGAAAACAGGGTGTTTTATCGAGTGTTTGGATGGGACGAAGTGAAACAGTgtttatatttgttgtttatatCTAATGTGTTTTATGGCGTGATAAATATCAGATACAATTTTTTTatactgttcatttattaattcccTAGAGTGCCTAGTGCTTGAGCTATCAGGCCAGAGCTGCTTTTTGTATTGTAATGAGAAttctatacagtatatatataaaatttatatatatatataaaaaatgtaacatttgaaGTAGCTTTAGCTTTATCATTTCAATTTCTTGTCACAGCCACAAGAATTTAAACTAGCATTTGATATAATATGTATGTACAGATTTATCCTCTTAACcaaatgtttacaatttaaatatatagTAGATTTTTGTAGAAAGGGAGTGAAATTTGAAGAACCGGCTTTAACTGTAAATGGATGTTTCTGAGAAGAAGTCTAGTTGTTGCTttgtaatataaaacaattaagttcatCACACGACTAGGTGCAATCTTGTATATTGGCTCTTAACTGTAATTCATGTTTGCTTCTGATACTTGAACCTTATTTTGTAATATCTTtcctttttttgttaaaataatatttatttatttgtactagTCTGTGTTTCATGCACTTTGTTCATAACTGAGATTCTAGAGCATATCAGCAAATACAATTGTTTCTTTCTGAAGAAAGTGAATTATCTATATGCGATTACCGAATCAATAAAGAGTCTAAAAGAGAATGTGtgggtttttgtttttgtaaaaaaaaaaaataataaataataataataaaaaa
>TCONS_00055803
aTGAGATGCCATATCTGAAGTGTCCTCTCCACACCGTACTCAAGCTGACCCCAGTGGCTTACGGATGCAAAGTGGAATCTATCTCTCTGAATGTGGAGGCAgtgaacacacacagagaaagaccAGAGGAGGTGAAGCGAGGCCCAAGCACTCTGATCAGGAGAAACAGCGTGACTCCTCTCACCAGCCATGAACCTTTTAAGAAGCCTCGTATCGATGGTCTGGATGAGCCAATCATCAGAGAAGTGATGCCGGCTCAACTTGCTCTCTGCTCAGCCTCACACACCACACTGGCTCTGTCCACACAGAACTGGCTTAGCGAAGCTTGTCTAACCTGAAGAAATGCTGTATAGAGTGCCATGAAGCCCCTCAGCTTTGCCTGTGAGATTATTCGGCTGTAAAGCTTTACTCGACGTGGAAGAGTTTCCTGTCAAGCTGCTTCCTCTCCTTTTCccacataaaaaaagaaatggacCCTTGGGTTTTTCCTATTTGTAAGGAATGCACATACTATGTGGTTTGTACTAGTAAGGAGTTTTTGGATATAAAGTGTATCCAGAGCACAGTGACAGGGATTACCAATTTATAACCCCCCACCTCCCCTGACATTTTTGGACACTATTCC
>TCONS_00055802
GGATTTGGTTCAGCGTGTGGAGCCGGTGATTATGGAAATGGAGCGACAGGAGAATGTTCTGGTCATCTGTCACCAGGCGGTGATTCGATGCCTACTCGCCTATTTCCTTGACAAAAGTGCAGaTGAGATGCCATATCTGAAGTGTCCTCTCCACACCGTACTCAAGCTGACCCCAGTGGCTTACGGATGCAAAGTGGAATCTATCTCTCTGAATGTGGAGGCAgtgaacacacacagagaaagaccAGAGGAGGTGAAGCGAGGCCCAAGCACTCTGATCAGGAGAAACAGCGTGACTCCTCTCACCAGCCATGAACCTTTTAAGAAGCCTCGTATCGATGGTCTGGATGAGCCAATCATCAGAGAAGTGATGCCGGCTCAACTTGCTCTCTGCTCAGCCTCACACACCACACTGGCTCTGTCCACACAGAACCTGAAGAAATGCTGTATAGAGTGCCATGAAGCCCCTCAGCTTTGCCTGTGAGATTATTCGGCTGTAAAGCTTTACTCGACGTGGAAGAGTTTCCTGTCAAGCTGCTTCCTCTCCTTTTCccacataaaaaaagaaatggacCCTTGGGTTTTTCCTATTTGTAAGGAATGCACATACTATGTGGTTTGTACTAGTAAGGAGTTTTTGGATATAAAGTGTATCCAGAGCACAGTGACAGGGATTACCAATTTATAACCCCCCACCTCCCCTGACATTTTTGGACACTATTCC
>TCONS_00055804
AGAATTTGAAGGATTTGAAGGTTTGGACCAGCCAGCTGAAGCGTAGTATCCAAACAGCAGAGGCTCTCAATGTGCCGTACGAACAGTGGAAAGCCCTCAATGAGATTGATGCCGGTGTGTGTGAGGAGATGACCTATGAAGAAGTCAGGGAGAGGTTTCCCGAGGAGTTTTCTCTTAGAGATCAGGACAAATACTACTACCGCTACCCTTCCGGAGAGTCATATCAGGATTTGGTTCAGCGTGTGGAGCCGGTGATTATGGAAATGGAGCGACAGGAGAATGTTCTGGTCATCTGTCACCAGGCGGTGATTCGATGCCTACTCGCCTATTTCCTTGACAAAAGTGCAGCAGTGCAGCCTTACTGACAtttaatttcctgttgccagaTGAGATGCCATATCTGAAGTGTCCTCTCCACACCGTACTCAAGCTGACCCCAGTGGCTTACGGATGCAAAGTGGAATCTATCTCTCTGAATGTGGAGGCAgtgaacacacacagagaaagaccAGAGGAGGTGAAGCGAGGCCCAAGCACTCTGATCAGGAGAAACAGCGTGACTCCTCTCACCAGCCATGAACCTTTTAAGAAGCCTCGTATCGATGGTCTGGATGAGCCAATCATCAGAGAAGTGATGCCGGCTCAACTTGCTCTCTGCTCAGCCTCACACACCACACTGGCTCTGTCCACACAGAACCTGAAGAAATGCTGTATAGAGTGCCATGAAGCCCCTCAGCTTTGCCTGTGAGATTATTCGGCTGTAAAGCTTTACTCGACGTGGAAGAGTTTCCTGTCAAGCTGCTTCCTCTCCTTTTCccacataaaaaaagaaatggacCCTTGGGTTTTTCCTATTTGTAAGGAATGCACATACTATGTGGTTTGTACTAGTAAGGAGTTTTTGGATATAAAGTGTATCCAGAGCACAGTGACAGGGATTACCAATTTATAACCCCCCACCTCCCCTGACATTTTTGGACACTATTCC

Function

symbol description
pfkfb3 Predicted to enable 6-phosphofructo-2-kinase activity and fructose-2,6-bisphosphate 2-phosphatase activity. Predicted to be involved in fructose 2,6-bisphosphate metabolic process. Predicted to act upstream of or within fructose metabolic process and phosphorylation. Predicted to be active in cytosol. Is expressed in Purkinje cell. Orthologous to human PFKFB3 (6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3).

GO:

id name namespace
GO:0016310 phosphorylation biological_process
GO:0006000 fructose metabolic process biological_process
GO:0006003 fructose 2,6-bisphosphate metabolic process biological_process
GO:0005829 cytosol cellular_component
GO:0003873 6-phosphofructo-2-kinase activity molecular_function
GO:0016740 transferase activity molecular_function
GO:0005524 ATP binding molecular_function
GO:0004331 fructose-2,6-bisphosphate 2-phosphatase activity molecular_function
GO:0016301 kinase activity molecular_function
GO:0003824 catalytic activity molecular_function

KEGG:

id description
ko00051 Fructose and mannose metabolism
ko04066 HIF-1 signaling pathway
ko04152 AMPK signaling pathway

ZFIN:

id description
ZDB-GENE-040426-2724 Predicted to enable 6-phosphofructo-2-kinase activity and fructose-2,6-bisphosphate 2-phosphatase activity. Predicted to be involved in fructose 2,6-bisphosphate metabolic process. Predicted to act upstream of or within fructose metabolic process and phosphorylation. Predicted to be active in cytosol. Is expressed in Purkinje cell. Orthologous to human PFKFB3 (6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3).

Ensembl:

ensembl_id ENSDARG00000001953

RNA

RNA id representative length rna type GC content exon number start site end site
TCONS_00055800 False 3525 mRNA 0.41 15 25472505 25485214
TCONS_00055801 False 3328 mRNA 0.41 17 25472966 25485404
TCONS_00055803 False 625 lncRNA 0.47 5 25474206 25478126
TCONS_00055802 False 724 processed_transcript 0.48 5 25474206 25478995
TCONS_00055804 True 988 lncRNA 0.48 7 25474206 25479379

Neighbor

gene id symbol gene type direction distance location
XLOC_028795 tmem110l coding downstream 201050 25251855 ~ 25271455 (-)
XLOC_028794 NA coding downstream 224657 25245031 ~ 25247848 (-)
XLOC_028793 itih2 coding downstream 256537 25187912 ~ 25215968 (-)
XLOC_028792 atp5f1c coding downstream 290953 25173299 ~ 25181552 (-)
XLOC_028791 taf3 coding downstream 304047 25084228 ~ 25168458 (-)
XLOC_028797 NA coding upstream 9052 25494456 ~ 25497067 (-)
XLOC_028798 rbm17 coding upstream 11700 25497104 ~ 25515591 (-)
XLOC_028799 tmcc3 coding upstream 269321 25754725 ~ 25812329 (-)
XLOC_028800 ndufa12 coding upstream 344437 25829841 ~ 25836684 (-)
XLOC_028801 nr2c1 coding upstream 352941 25838345 ~ 25859305 (-)
XLOC_028789 NA non-coding downstream 423498 24833526 ~ 25049007 (-)
XLOC_028788 NA non-coding downstream 681764 24726095 ~ 24790741 (-)
XLOC_028787 NA non-coding downstream 828996 24501129 ~ 24643509 (-)
XLOC_028786 NA non-coding downstream 1096480 24253766 ~ 24376025 (-)
XLOC_028802 BX640593.1 non-coding upstream 355382 25840786 ~ 25840902 (-)
XLOC_028804 CT573048.1 non-coding upstream 521038 26006442 ~ 26007456 (-)
XLOC_028807 BX957270.1 non-coding upstream 641773 26127177 ~ 26147550 (-)
XLOC_028808 NA non-coding upstream 765470 26250874 ~ 26252121 (-)

Expression


Co-expression Network