XLOC_029957 (chfr)



Basic Information


Item Value
gene id XLOC_029957
gene name chfr
gene type coding
species zebrafish (Danio rerio)
category of species model fish

Chromosome Information


Item Value
chromosome id NC_007116.7
NCBI id CM002889.2
chromosome length 72500376
location 17780475 ~ 17813299 (+)
genome version GRCz11_2017_zebrafish_Genome

Sequence


>TCONS_00058660
ACTATCAGCTGATGCCTGAAAATGCCACTGCTGGCCAGGAAGTGCTcaagaaaataaaaacgaaaCCACACTGAGGATCTAAGTCAACATGCTGTAATGCTCCCGACGTTCACGGACGCTGGTTTGGTGAAATAAGGACGAGGAGAAATGACAAATCAGGACAGCGATCAAGCCTGGGGGAAACTGGTGAAAGTGGACGCATCTCCAGGTTCGGAGATAGTGCTTATAAATAGTGAATGCACCGTTGGGAGAAAGAAAGATTGTGACCTCTCATTCCCAGCTAATAAACTGGTCTCAGGAAATCATTGCAAAATCACTCATGATCAAAACTCAGGAAAGGTGTGGCTGGAAGACATGAGCACCAACGGAACTGTGATCAACATGTCCAAAGTAGTGAAGAAACAGACGCACTTACTGCAGAACGGTGATGTCATTTACTTTGTGTACAGGAAGAACGAGCCAGAGCAAAACATTGCTTATGTTTATCAGTCCATCACGCCACAGGAAAGTGCCTCACATGATGTTGAAGATGCAGGGAGAGAAGAAGATTCTGATCTGACAGAAACGGAGAGTGAACCAGCACCAGTAGAGCCTGTTATCGTGAAGCCTTTACCTCAGTCTGGACATGAGGATCCTCAGCCATCTACCTCCAGCTCTTCCTTACACTTCTACAACATGCCATTGTCTACCTGCTCTGATGTGTCTGCAAGAAAGAATCCAGTCAGTTCTTCAGCTGTTTGTAAAGGAGACTCTACTTCATCAGGAAGTCCCGCTCAAACCCGGCTGAAGTGGACCTGCTGGACTGATGGAGAGCCGGAGGAGGAAATGCAGAGGAAAAGAAGAAAAACTGACAGAGATGATCCAGGGTTTGGATCTGCTCACAGTGATGCTTCTGCTGACATTCCCCTCAGAGGAGCAAGTGGAAAAGAAAAAACTGAAGGAGCCACAACAGACAAGATGGAGGAATCCCTCACATGCATCATCTGTCAGGACCTGCTATATGACTGCATCAGtGTTCAGCCTTGCATGCATACGTTTTGTGCGGCCTGTTATTCTGGCTGGATGGAGCGTTCCTCTTTCTGTCCCACCTGTCGATGTCCTGTGGAGAGGATCCGCAAAAACCACATCCTCAACAACCTGGTGGAGGCTTACCTTCTCCAGCACCCGGAGAAGTGTCGGACTGAAGATGATTTGCGCAGTATGGATGCCAGAAACAAGATCACACAGGACATGCTGCAGCCGAAGGTCGAGCGATCGTTCTCAGACGAGGAGGCCAGTTCAGACTATCTGTTTGAACTCTCAGACAATGACAGCGACATTTCTGACATGAGCCAACCCTACATGATGTGTCGTCAGTGTCCGGGTTATCGAAAGGAACTCAGCTCGGCCCTGTGGATCTGCGAGTCGGCACAATCAGAGAGTCTGGCTAAAACTGCTGGAGACGGTCCCTCTACATCCTCTGATTCCACCACAGCAGCTCCTCAGGAGTTCAGATGTCCTCCTCAGGCCAGTCACCTGATCTGCACCTGCTGTCTGCAGCCCATGCCGGACCGCCGCTTCGAGCACCTTCCCCCTCAGGTGTCCCCGCAGCACTGTTTGGTGTGCCAGAAACCGTTCTGTCACGTGTACTGGGGCTGCCCGCGGATCGGCTGTCATGGCTGTTTAGCACGTTTCAGCGAACTAAACCTCAATGATAAATGTCTGGATGGAGTTTTTAATGGCAATCAATACGAGTCGGAGGTCCTTCAGaatTATCTGAGCTGTCGAGGGATGAGCTGGAGGCATTTGCTGCAGGACTCGCTGCAGGCTCTACAGCAGGGGCTCTACCATCTCTCTGATTATAGAATCACTGCCAACTCTTTTCTGTGCTACTGCTGTGGACTTCGCACTTTTCGAGAGCTCGCATACAAATACAGAGAGCGTATTCCTCCATCAGAGCTTCCAGATGCTGTGACCAACAGACCGAACTGTTACTGGGGACGCAACTGTCGAACTCAAGTGAAAGCACATCATGCACTGAAGTTCAACCACATATGTGAGCAGACCCGTTTTAAGAACTGAGGCTGACGGAGTGGCTCATTGTTTAAACAGCACTGGTTTGGGATGGTTGTTCATCTCAGTAGCTTCATTATCCGGTTGCTTATAAGTAACTACGACTGGTGGTAAACCTCCCATTACACATGCAAAGTCAATCAGATGATCATAAAGCAGTCATCCATCAGCGGAAACATTTGGTCTGCATCTACACTTATATGGACATATTTTCCCTTCATTTCACTGCTTTGTCCATTTGCTTTGCATCTCTGCTTgtaattgtaaaacaaaataatgctggcaatcacttttaaaaatatatatgtatacaaaatACACAATAACTAACCTTTAGTGCCTAAAAGGATGCATTTTCTGTGCAAATGTCACTTAGTTCTTCCTTTTCAATGTAACGGTATCGTTATTCCATGCTACTGAGAACATCAAAAATTGATGTAtgatatataaaagaaaaaagggATCTTGTTGTAGAGGTGATTTACGATCAAGTGCACTAAACTCTCACACTAGCAACGGTAGCTGAAACATGTGCTTTTTAGGCCAGTAATGTATGAATGTGTTCTGATTCGCAGGGCAGACGTACAGTGTGAGAGATGCTTTTGTAAGAGGAGACTGAGGGTTTTATCGCACTGCAGGGGATAATCAAGTCAAATCTGATGTTTAATAAAGATTTCGATGCTTTCGCA
>TCONS_00058661
agaaaataaaaacgaaaCCACACTGAGGATCTAAGTCAACATGCTGTAATGCTCCCGACGTTCACGGACGCTGGTTTGGTGAAATAAGGACGAGGAGAAATGACAAATCAGGACAGCGATCAAGCCTGGGGGAAACTGGTGAAAGTGGACGCATCTCCAGGTTCGGAGATAGTGCTTATAAATAGTGAATGCACCGTTGGGAGAAAGAAAGATTGTGACCTCTCATTCCCAGCTAATAAACTGGTCTCAGGAAATCATTGCAAAATCACTCATGATCAAAACTCAGGAAAGGTGTGGCTGGAAGACATGAGCACCAACGGAACTGTGATCAACATGTCCAAAGTAGTGAAGAAACAGACGCACTTACTGCAGAACGGTGATGTCATTTACTTTGTGTACAGGAAGAACGAGCCAGAGCAAAACATTGCTTATGTTTATCAGTCCATCACGCCACAGGAAAGTGCCTCACATGATGTTGAAGATGCAGGGAGAGAAGAAGATTCTGATCTGACAGAAACGGAGAGTGAACCAGCACCAGTAGAGCCTGTTATCGTGAAGCCTTTACCTCAGTCTGGACATGAGGATCCTCAGCCATCTACCTCCAGCTCTTCCTTACACTTCTACAACATGCCATTGTCTACCTGCTCTGATGTGTCTGCAAGAAAGAATCCAGTCAGTTCTTCAGCTGTTTGTAAAGGAGACTCTACTTCATCAGGAAGTCCCGCTCAAACCCGGCTGAAGTGGACCTGCTGGACTGATGGAGAGCCGGAGGAGGAAATGCAGAGGAAAAGAAGAAAAACTGACAGAGATGATCCAGGGTTTGGATCTGCTCACAGTGATGCTTCTGCTGACATTCCCCTCAGAGGAGCAAGTGGAAAAGAAAAAACTGAAGGAGCCACAACAGACAAGATGGAGGAATCCCTCACATGCATCATCTGTCAGGACCTGCTATATGACTGCATCAGtGTTCAGCCTTGCATGCATACGTTTTGTGCGGCCTGTTATTCTGGCTGGATGGAGCGTTCCTCTTTCTGTCCCACCTGTCGATGTCCTGTGGAGAGGATCCGCAAAAACCACATCCTCAACAACCTGGTGGAGGCTTACCTTCTCCAGCACCCGGAGAAGTGTCGGACTGAAGATGATTTGCGCAGTATGGATGCCAGAAACAAGATCACACAGGACATGCTGCAGCCGAAGGTCGAGCGATCGTTCTCAGACGAGGAGGCCAGTTCAGACTATCTGTTTGAACTCTCAGACAATGACAGCGACATTTCTGACATGAGCCAACCCTACATGATGTGTCGTCAGTGTCCGGGTTATCGAAAGGAACTCAGCTCGGCCCTGTGGATCTGCGAGTCGGCACAATCAGAGAGTCTGGCTAAAACTGCTGGAGACGGTCCCTCTACATCCTCTGATTCCACCACAGCTCCTCAGGAGTTCAGATGTCCTCCTCAGGCCAGTCACCTGATCTGCACCTGCTGTCTGCAGCCCATGCCGGACCGCCGCTTCGAGCACCTTCCCCCTCAGGTGTCCCCGCAGCACTGTTTGGTGTGCCAGAAACCGTTCTGTCACGTGTACTGGGGCTGCCCGCGGATCGGCTGTCATGGCTGTTTAGCACGTTTCAGCGAACTAAACCTCAATGATAAATGTCTGGATGGAGTTTTTAATGGCAATCAATACGAGTCGGAGGTCCTTCAGaatTATCTGAGCTGTCGAGGGATGAGCTGGAGGCATTTGCTGCAGGACTCGCTGCAGGCTCTACAGCAGGGGCTCTACCATCTCTCTGATTATAGAATCACTGCCAACTCTTTTCTGTGCTACTGCTGTGGACTTCGCACTTTTCGAGAGCTCGCATACAAATACAGAGAGCGTATTCCTCCATCAGAGCTTCCAGATGCTGTGACCAACAGACCGAACTGTTACTGGGGACGCAACTGTCGAACTCAAGTGAAAGCACATCATGCACTGAAGTTCAACCACATATGTGAGCAGACCCGTTTTAAGAACTGAGGCTGACGGAGTGGCTCATTGTTTAAACAGCACTGGGCAGACGTACAGTGTGAGAGATGCTTTTGTAAGAGGAGACTGAGGGTTTTATCGCACTGCAGGGGATAATCAAGTCAAATCTGATGTTTAATAAAGATTTCGATGCTTTCGC

Function


symbol description
chfr Predicted to enable nucleotide binding activity and ubiquitin-protein transferase activity. Predicted to be involved in protein polyubiquitination and ubiquitin-dependent protein catabolic process. Predicted to act upstream of or within cell division. Predicted to be located in PML body. Predicted to be active in nucleus. Is expressed in central nervous system and presumptive diencephalon. Orthologous to human CHFR (checkpoint with forkhead and ring finger domains).

GO:

id name namespace
GO:0007049 cell cycle biological_process
GO:0016567 protein ubiquitination biological_process
GO:0019941 modification-dependent protein catabolic process biological_process
GO:0051301 cell division biological_process
GO:0006511 ubiquitin-dependent protein catabolic process biological_process
GO:0000209 protein polyubiquitination biological_process
GO:0007093 mitotic cell cycle checkpoint biological_process
GO:0005634 nucleus cellular_component
GO:0016605 PML body cellular_component
GO:0016740 transferase activity molecular_function
GO:0046872 metal ion binding molecular_function
GO:0004842 ubiquitin-protein transferase activity molecular_function
GO:0000166 nucleotide binding molecular_function

KEGG:

id description
ko04121 Ubiquitin system

ZFIN:

id description
ZDB-GENE-030131-3522 Predicted to enable nucleotide binding activity and ubiquitin-protein transferase activity. Predicted to be involved in protein polyubiquitination and ubiquitin-dependent protein catabolic process. Predicted to act upstream of or within cell division. Predicted to be located in PML body. Predicted to be active in nucleus. Is expressed in central nervous system and presumptive diencephalon. Orthologous to human CHFR (checkpoint with forkhead and ring finger domains).

Ensembl:

ensembl_id ENSDARG00000075347

RNA


RNA id representative length rna type GC content exon number start site end site
TCONS_00058660 False 2741 mRNA 0.47 18 17780475 17813299
TCONS_00058661 True 2158 mRNA 0.49 19 17780523 17813298

Neighbor


gene id symbol gene type direction distance location
XLOC_029956 fbrsl1 coding upstream 26514 17624463 ~ 17753961 (+)
XLOC_029955 NA coding upstream 237859 17309732 ~ 17542616 (+)
XLOC_029953 NA coding upstream 711037 17051806 ~ 17069438 (+)
XLOC_029954 NA coding upstream 723517 17054316 ~ 17056958 (+)
XLOC_029952 CR759970.2 coding upstream 751061 17029298 ~ 17029414 (+)
XLOC_029958 ascc2 coding downstream 198855 18012154 ~ 18035253 (+)
XLOC_029959 hira coding downstream 233812 18047111 ~ 18072844 (+)
XLOC_029960 NA coding downstream 520729 18334028 ~ 18334386 (+)
XLOC_029961 NA coding downstream 988888 18802187 ~ 18803334 (+)
XLOC_029962 NA coding downstream 995415 18808714 ~ 18810213 (+)
XLOC_029950 NA non-coding upstream 1420444 16353235 ~ 16360031 (+)
XLOC_029963 NA non-coding downstream 1009512 18822811 ~ 19037584 (+)
XLOC_029964 NA non-coding downstream 1011095 18824394 ~ 18826765 (+)

Expression



Co-expression Network


Homologous


species gene id symbol gene type chromosome NCBI id location
bowfin (Amia calva) AMCG00018644 chfr,LOC100195666,LOC106580459,LOC102788874 coding CM030135.1 CM030135.1 16438631 ~ 16462363 (-)