LOC118936277 (prf1)


Basic Information

Item Value
gene id LOC118936277
gene name prf1
gene type coding
species rainbow trout (Oncorhynchus mykiss)
category of species economic fish

Chromosome Information

Item Value
chromosome id NC_048577.1
NCBI id CM023231.2
chromosome length 73332040
location 49134951 ~ 49138251 (+)
genome version USDA_OmykA_1.1_2020_rainbow_trout_Genome

Sequence

>XM_036941384.1
CTATTCTGTGGCAGACACTCTTTTGCGTCGTCTATACTGAGACCAACATCCCCTCAACCTTCCATTTGCTCGTCCCGTTTGAGTACGAACACACCTTTTCCTATATCAAAAAGGAACTTAATTACGGTACATTATTGCCCCAGCCTCTCACATCCATCACATAGTGGACAGACTGGTCAAAGCATGAAACAGTGACTTGTAGCTGCCCGTCGCAAACATCTCACCTCATCCAGAATGTCCTTATTGATAGTGTGCCTCTGGGCAGGGCTTATGTTGTCCATTCCTCGTCCCAGTTGCCAATCATGCACCATCGGCTCAGCCAATGAGTGCAAAGAGGCAGAATTTGCTCCTGGAACCAACCTAGCAGGGGAAGGCTTTGACATCACCAAAATGAAACGCAAAGGAGCCTTTGTCATTGACATGAACGTGTGGAAACGCAAAGACAAGACCTGCACCCTCTGTAAGAATCCCTATCTGGAAGGGAAACAACAGAGGCTTCCTTTGGCAGTGGTGGATTGGAGACCAAACCACCAGTGTAGTATGAAAGTGTCCAGTAAACTCCATCGCTCCAGCGAGTCTCTCGTCAGCTCCAGTGGCTCTTCTGTGGAGAATAACTGGCAGGTCAATCTAGAGTTAGAGAAGGGATCAAAAAGTGGGAAGATTATGCTCGCTGGAACCAACTCCAAATTGGCTGAGTACTCCATGGAGAAAACCAAGAGTGACAAGTTCAGTTTCACAAGCCACAGTGTGTCCTGCGGGTATTACAGCTATCGAGTATCTGGCCAGCCCAAGTTACACAAAGAATTCAAGACAGCAGTGAAGAATCTCCCCAAAATATATCAACAAGAAAACAAACAACGTTATTACAAGCTTATTGATAACTTTGGCACGCATTACATTAccaagGTGAGCCTGGGTGGAACGGTGCAGTCTGTGACCAGTATCAAGCAGTGCCAGGCCAGCCTGCAGGGTCTCAGTGCGGAGGAGGTGAAGATGTGTCTGGATGTGGAGGCGTCTGCCAGTGTGGGTGACAGCAACAGCTTGAAGACTGAGTTCAAGCACTGCCAGGAGGATAAGTCTAAGACAGAGAGCAAGGCCAGCTTCTCCAGTGTCTTCAATGATAGGTTCACAGAGGTGAAAGGTGGCCACACCACAGAACCAGAGCTCCTCTTCTCTGCTGATAAATATCCCGCCTCCTACAAGGAATGGCTGAACTCCCTACCACACTATCCGGACATCGTCTCCTATTCGCTGGAATCTCTCCATGAGTTGCTGCCCACCACCAACCCAGCTCGGAAGCACTTGCGCAAGGCCATCAGCGACTACATCCTGGAGAAGGCCTTGTGGAAGAACTGTTCTGAACCCTGTCAAACTGGCATCAAAAGTGACCACAGAGACTCCTGCGTCTGCAGCTGCCACAACATCCCCGGGGTGAGCGCCGACTGCTGCCCCACACGCAAGGGACTGGCGCGGGTGGTCATCACTGTTCAGAGAGGGGCCAACCTGTGGGGAGACCACACCACTGCCACTGACGGCTACGTGAAGGTGGCTTTCGCAGGCCAGATAATCGGACGCACTAAAGTtatctacaacaacaacaaccccaGCTGGGCAATGAGCTATGACCTGGGAACCGTGGATCTGTCAACCAGTAAGAAGCTGAGATTTGAGGTGTGGGACGAGGACGACAAGTGGAATGACGACCTGTTAGGAGAATGTGAGAAGGAGCTGACAGCCGGGGTGAAGGAGGATCTCTGCAACCTCCAGCATGGCCAAATGTTCTACAAGTGGGAGGCGGTGTGTGCCCCCAGTCTAGGTGGCTCCGCCTGTATGGACTATGTGCCCTCCCCTATGAATCCCCACCTGGAGAAGGTTTATGTGTCTCGCCACTCCCGTCTCATTCCAAAGGACATGCTGGTGAGTATGGGAGTCTTGTTGGACGGACCCAATCTCCATGGCAACAAGAGCCTCAGTACAGGGAACAGGGAGTCTGGTCGATTTTAGAGGTATGCATGGTGATCTATGTCAAAACCCCACATCTTTTTTCAGGTAGATTTCTCCAAcctaaaataataaaataaatgttttgttaaaatgtgttttgttttctatACTGTATCTTTgaactcccgagtggtgcagaggtctt

Function

symbol description
prf1 Enables identical protein binding activity and wide pore channel activity. Involved in immunological synapse formation; positive regulation of killing of cells of other organism; and protein homooligomerization. Located in cytolytic granule and cytosol. Is integral component of membrane. Implicated in several diseases, including Crohn's disease; familial hemophagocytic lymphohistiocytosis 2; human immunodeficiency virus infectious disease; multiple sclerosis; and non-Langerhans-cell histiocytosis. Biomarker of Fanconi anemia; chronic fatigue syndrome; human immunodeficiency virus infectious disease; multiple sclerosis; and systemic lupus erythematosus.

NR:

description
perforin-1-like

GO: NA

KEGG:

id description
K07818 PRF1; perforin 1

RNA

RNA id representative length rna type GC content exon number start site end site
XM_036941384.1 True 2149 mRNA 0.50 5 49134951 49138251

Neighbor

gene id symbol gene type direction distance location
LOC110486662 LOC106606881 coding upstream 30915 49100007 ~ 49104036 (+)
LOC110486658 NA coding upstream 175749 48957777 ~ 48959202 (+)
LOC118938635 NA coding upstream 176186 48958678 ~ 48958765 (+)
LOC118938636 NA coding upstream 176441 48958422 ~ 48958510 (+)
LOC118938637 NA coding upstream 176675 48958189 ~ 48958276 (+)
LOC110486671 LOC100335037 coding downstream 60595 49198846 ~ 49202693 (+)
LOC110486670 LOC106606891 coding downstream 72214 49210465 ~ 49213419 (+)
LOC110486678 NA coding downstream 125278 49263529 ~ 49266771 (+)
LOC110486677 LOC106601591 coding downstream 142855 49281106 ~ 49284116 (+)
LOC100136718 mlc-2 coding downstream 157085 49295336 ~ 49299251 (+)
G1182591 NA non-coding upstream 80934 49053596 ~ 49054017 (+)
G1182588 NA non-coding upstream 88266 49045076 ~ 49046685 (+)
G1182587 NA non-coding upstream 90174 49044482 ~ 49044777 (+)
G1182585 NA non-coding upstream 101566 49033108 ~ 49033385 (+)
G1182584 NA non-coding upstream 102730 49029765 ~ 49032221 (+)
G1182611 NA non-coding downstream 161950 49300201 ~ 49303631 (+)
G1182700 LOC106606901 non-coding downstream 171849 49310100 ~ 49311267 (+)
G1182705 NA non-coding downstream 181552 49319803 ~ 49320131 (+)
G1182707 NA non-coding downstream 185687 49323938 ~ 49324173 (+)
G1182711 LOC106585476 non-coding downstream 212144 49350395 ~ 49352361 (+)
G1182629 NA other upstream 16254 49114975 ~ 49118697 (+)
G1182595 NA other upstream 69809 49063785 ~ 49065142 (+)
G1182555 NA other upstream 153548 48978000 ~ 48981403 (+)
G1182541 NA other upstream 186982 48946749 ~ 48947969 (+)
G1182354 LOC106601550 other upstream 573327 48556014 ~ 48561624 (+)
G1182742 NA other downstream 281319 49419570 ~ 49426223 (+)
ndua4 ndua4 other downstream 442075 49580324 ~ 49584562 (+)

Expression


Co-expression Network