XLOC_003115 (timp4.1)


Basic Information

Item Value
gene id XLOC_003115
gene name timp4.1
gene type coding
species zebrafish (Danio rerio)
category of species model fish

Chromosome Information

Item Value
chromosome id NC_007122.7
NCBI id CM002895.2
chromosome length 45484837
location 691734 ~ 701305 (+)
genome version GRCz11_2017_zebrafish_Genome

Sequence

>TCONS_00006156
aatttaaaaaatcaatacaAACTCAGTACATATAAAGCAGTTTCACATCAAAATGCATATTTGTTTTTCTACCTTCCCCATCCCAGAATGAGCATGTCCAATCTTCACCACCACTGGGAATGTTGGCATCGAGATCTGAAACACAGAGTCATTGTCCTCATTattgactattattattacagttattgATCCATATTTACATTAATTACCAACACAGATCCTGGAACTGCTCATTGCGTATAAAACCACGTCATTTAATCCATGCTGGAACAATAGATGGTGCGTGAGTAAAGGTGCAGTTTCCCAGCACAGAAACAGAAACCAGTTATGAATAATTCGGTGggtcactgttgcctcacagcaagaaggtcgcaggtttgagtcccggctgggtcagttggtgtttctgtgtggagtttgcatgttctccccgtgttggcgtgggtttcctcccggtgctccggtttcccccacagtccaaacacatgcgctataggggaactgatcaactaaattggctgtgtgtgtgtgtgtgtgtgagaatgagtgtgtatgggtgtttcccagtgatgggttgcagctggatgggcatccgccgtttgaaacgtgtgtgtgtgtgtgtgtgtgtgagagagagagagagagagagagtaagagacAGAGAGTcaaagtgtgtgtttgagagtgtgtgtgtattgtgcgtgtgtattgtgtgtgtgttcagagggTGGGGTTTGTTTAGTTAGAAGGTGGTCCTTTCCTCGGCCACACATGAAAGCTATAAGACAGCCGGAGCTCCTTGAGAGTGTGTGAGACACAGACTGCTGTGTGgagtgtgatgatgatgatgatgatgatgaagatgtgcACTCGCGAGTGTGTGACTGCAGGTCTGCTgttctttatgtgtgtgtgtctgaatcagCAGATGCTGGAGGCCTGCAGCTGCGCGTCTGCACATCCACAACAGCTCTTCTGCAGCGCTGACGCAGTGCTGCGGGCAGAGATAACCGGAGAGAAGATCAGGCGCAGAGAAGACATTAACCCGATGTACGGCCTGGGGAAAATACAGTATGAGGTGCAGGTGATCAAGGTGTTCAAGGGCTCGGACAGGATAAAAGACCTCCAGCATGTCTACACGCATGAGATGTCTTCAATGTGCGGGATCAGACTGAACCGTGGCCAGTATCTGCTCTCAGGAAGTATGATGTCTGAGGGATTCTTTGTCACACTGTGTGACTTTGTTGAGCACTGGGACAGACTCTCCTTAACGCAGAAGAAAAACCTCAAATACAGATATCAGATGGGCTGTAACTGCACGATATCCATCTGCACTGAACAGCCCTGTCACCCCAAGGTAAAAAACGAGTGTATCCTGACAGACTGGTCATCCTTGTGGCCATTTGAGGATGGAGAACCAGTTCATGAATATGCCTGCATCCGACACAGTGATGGCTCCTGCAGCTGGCATGAAGGAGGAACATCCGTACCTTCTGAAAAAAACACCACAGACATTTCTGAAGGCTGA

Function

symbol description
timp4.1 Predicted to enable metalloendopeptidase inhibitor activity and protease binding activity. Predicted to be involved in negative regulation of proteolysis; response to cytokine; and response to hormone. Predicted to act upstream of or within negative regulation of peptidase activity. Predicted to be located in extracellular region. Predicted to be active in extracellular matrix and extracellular space. Is expressed in prechordal plate. Human ortholog(s) of this gene implicated in nephroblastoma. Orthologous to human TIMP4 (TIMP metallopeptidase inhibitor 4).

GO:

id name namespace
GO:0010951 negative regulation of endopeptidase activity biological_process
GO:0051045 negative regulation of membrane protein ectodomain proteolysis biological_process
GO:0009725 response to hormone biological_process
GO:0034097 response to cytokine biological_process
GO:0010033 response to organic substance biological_process
GO:0031012 extracellular matrix cellular_component
GO:0005576 extracellular region cellular_component
GO:0005615 extracellular space cellular_component
GO:0002020 protease binding molecular_function
GO:0008191 metalloendopeptidase inhibitor activity molecular_function

KEGG: NA

ZFIN:

id description
ZDB-GENE-100603-1 Predicted to enable metalloendopeptidase inhibitor activity and protease binding activity. Predicted to be involved in negative regulation of proteolysis; response to cytokine; and response to hormone. Predicted to act upstream of or within negative regulation of peptidase activity. Predicted to be located in extracellular region. Predicted to be active in extracellular matrix and extracellular space. Is expressed in prechordal plate. Human ortholog(s) of this gene implicated in nephroblastoma. Orthologous to human TIMP4 (TIMP metallopeptidase inhibitor 4).

Ensembl:

ensembl_id ENSDARG00000111805

RNA

RNA id representative length rna type GC content exon number start site end site
TCONS_00006156 True 1528 mRNA 0.47 5 691734 701305

Neighbor

gene id symbol gene type direction distance location
XLOC_003114 mkrn2os.2 coding upstream 102606 583142 ~ 589128 (+)
XLOC_003113 mkrn2os.1 coding upstream 110901 575665 ~ 580833 (+)
XLOC_003112 NA coding upstream 147540 543348 ~ 544194 (+)
XLOC_003111 raf1b coding upstream 151482 506465 ~ 540252 (+)
XLOC_003109 NA coding upstream 186905 474380 ~ 504829 (+)
XLOC_003116 timp4.2 coding downstream 4422 705727 ~ 711032 (+)
XLOC_003117 timp4.3 coding downstream 13081 714386 ~ 718748 (+)
XLOC_003118 FQ311892.1 coding downstream 29502 730807 ~ 730923 (+)
XLOC_003119 vgll4b coding downstream 68318 769623 ~ 772459 (+)
XLOC_003120 tamm41 coding downstream 78449 779754 ~ 790304 (+)
XLOC_003250 BX324177.11 misc downstream 10644498 11345803 ~ 11346099 (+)
XLOC_003255 BX324177.14 misc downstream 10671581 11372886 ~ 11373182 (+)
XLOC_003257 BX324177.13 misc downstream 10685057 11386362 ~ 11386658 (+)
XLOC_003260 BX324177.2 misc downstream 10716728 11418033 ~ 11418323 (+)
XLOC_003262 BX324177.15 misc downstream 10728088 11429393 ~ 11429689 (+)
XLOC_003110 NA non-coding upstream 197201 489935 ~ 494533 (+)
XLOC_003107 CR855375.1 non-coding upstream 320294 371322 ~ 371440 (+)
XLOC_003104 NA non-coding upstream 392635 298450 ~ 299099 (+)
XLOC_003126 AL935272.1 non-coding downstream 844812 1546117 ~ 1546231 (+)
XLOC_003132 NA non-coding downstream 1234379 1935684 ~ 1997410 (+)
XLOC_003133 NA non-coding downstream 1250326 1951631 ~ 1952594 (+)
XLOC_003138 mir196c non-coding downstream 1489316 2190621 ~ 2190730 (+)

Expression


Co-expression Network