XLOC_031219 (hexb)



Basic Information


Item Value
gene id XLOC_031219
gene name hexb
gene type coding
species zebrafish (Danio rerio)
category of species model fish

Chromosome Information


Item Value
chromosome id NC_007116.7
NCBI id CM002889.2
chromosome length 72500376
location 34600714 ~ 34616599 (-)
genome version GRCz11_2017_zebrafish_Genome

Sequence


>TCONS_00060629
acacacacgaacaGTCCTCCGCTCAGACTGGAAGCAGAGTCAGTCAGCTGACCGCTCAACACAACCATGCTCTGTCTGCTCAAGTTTACCCCTCTGTTTTTGGTGGTAGCCGTATGTCACGGCTGGCTTTTTGGAGATCTTTTTGAAAAACAGAAAGAGCTGGATGAAATCTCTCTATGGCCTCTACCGCAGAAATACCAGTCGTCCGCGGTCGCTTTTAAACTCAGCGCCGCCAGCTTTCAAATCGTCCACGCCAAACAGTCCACCGCCGGACCGAGCTGCAGTCTACTCGAGAATGCATTTCGCAGATATTTTGAATACATGTTTGGAGAGCTGAAAAGGCAGGAGAAAAGCCGAAAGAAAGCGTTTGATTCAGATCTCTCGGAGCTGCAGGTATGGATCACATCAGCTGATCCGGAGTGCGACGGTTACCCGAGTCTTCGAACCGACGAGTCATATTCGCTGTCGGTTGATGAAACCTCAGCTGTGCTCAAAGCTGCTAATGTATGGGGAGCTTTGCGAGgACTGGAAACATTCAGCCAGTTGGTCTATGAGGATGACTATGGAGTTAGAAATATTAATAAGACCGACATATCAGATTTTCCACGGTTTGCCCACCGAGGAATCCTTCTGGACTCGTCTCGCCATTTTCTGCCACTCAAAGTCATTTTGGCCAACTTGgaagcTATGGCCATGAACAAGTTTAACGTCTTCCACTGGCACATTGTGGATGATCCGTCGTTTCCTTTTATGAGCCGTACTTTCCCAGAGTTGAGCCAAAAGGGAGCCTATCACCCATTTACACATGTGTACACTCCATCTGATGTGAAGATGGTCATTGAATTTGCTCGCATGAGGGGGATCAGGGTCGTTGCGGAGTTCGACACCCCAGGGCACACGCAGTCATGGGGCAATGGCATAAAGGATCTGCTAACACCTTGTTACAGTGGCTCTAGTCCTTCAGGATCATTTGGGCCCGTGAACCCCATCTTAAACTCCTCTTATGAGTTCATGGCACAGCTTTTCAAAGAGATCAGCACCGTCTTTCCTGACGCTTACATTCACCTAGGGGGAGATGAGGTCGACTTTTCTTGTTGGAAGTCCAATCCTGATATTCAGAAGTTTATGAATCAGCAAGGCTTTGGCACAGACTACAGCAAACTGGAGTCCTTCTACATTCAAAGGTTACTTGATATTGTGGCTGCTACCAAAAAAGGTTACATGGTGTGGCAGGAGGTGTTTGATAACGGGGTCAAGCTAAAGGATGACACTGTTGTGGAGGTGTGGAAAGGGAACGATATGAAGGAGGAGCTCCAGAATGTGACTGGGGCAGGATTTACAACCATTCTTTCTGCCCCTTGGTACCTGGACTACATTAGCTATGGACAGGACTGGCAACGCTACTACAAAGTTGAGCCACTTGATTTCACTGGCACAGATGCACAGAAGAAGCTGGTGATTGGTGGAGAGGCTTGTCTTTGGGGAGAGTATGTGGACGCCACCAACCTCACTCCTCGACTCTGGCCAAGAGCCAGTGCCGTCGCTGAGAGGTTATGGAGTGATGCAAGCGTGACCGATGTCGGAAATGCTTATACTCGCCTGGCCCAGCATCGCTGCCGCATGGTCAGGAGAGGCATACCTGCAGAACCTCTATTTGTTGGCCACTGCCGTCATGAGTACAAGGGTCTGTGAATGCCATGATTTAGTTCACAGTAGACGACTAAAGGGAAGgacaaaacagtttttatttttacagattaAACCATGTTAGCCATTTGGAGAACTATGATTTGCTGTTATATGCACTGAGCCAGTTATCTAAGACTTGATGTTTGTGATTTTTACCTATACAAAGTTTTACTACAATACTTAGGTTTCAGGTTTATTAAATGGTAAGTAATATTCCTGTGAAAACATTTTATGGAATGTGTTTTATAATGAATGCTAGGTGTATTCTGAGGGTTTACATGATTGTAACACTGcactaaatttatatatttaaataaatacgaTTTCTGAAAGCA
>TCONS_00060630
GGGGGATCAGGGTCGTTGCGGAGTTCGACACCCCAGGGCACACGCAGTCATGGGGCAATGGCATAAAGGATCTGCTAACACCTTGTTACAGTGGCTCTAGTCCTTCAGGATCATTTGGGCCCGTGAACCCCATCTTAAACTCCTCTTATGAGTTCATGGCACAGCTTTTCAAAGAGATCAGCACCGTCTTTCCTGACGCTTACATTCACCTAGGGGGAGATGAGGTCGACTTTTCTTGTTGGAAGTCCAATCCTGATATTCAGAAGTTTATGAATCAGCAAGGCTTTGGCACAGACTACAGCAAACTGGAGTCCTTCTACATTCAAAGGTTACTTGATATTGTGGCTGCTACCAAAAAAGGTTACATGGTGTGGCAGGAGGTGTTTGATAACGGGGTCAAGCTGAAAGCCGACACACAGATCCATGTGTGGAAAGGCAGGCCGCAATACCAGGATGAGATGGCGAAGGTAACGGCGGCTGGTTTCAGCGCTCTGCTCTCCACACCCTGGTACCTCAACCGAGTCAGCTACGGCCAGGACTGGGTGGATATTTACAAAGCTGACCCCCAAAACTTCAACGGCACAGATGCACAGAAGAAGCTGGTGATTGGTGGAGAGGCTTGTCTTTGGGGAGAGTATGTGGACGCCACCAACCTCACTCCTCGACTCTGGCCAAGAGCCAGTGCCGTCGCTGAGAGGTTATGGAGTGATGCAAGCGTGACCGATGTCGGAAATGCTTATACTCGCCTGGCCCAGCATCGCTGCCGCATGGTCAGGAGAGGCATACCTGCAGAACCTCTATTTGTTGGCCACTGCCGTCATGAGTACAAGGGTCTGTGAATGCCATGATTTAGTTCACAGTAGACGACTAAAGGGAAGgacaaaacagtttttatttttacagattaAACCATGTTAGCCATTTGGAGAACTATGATTTGCTGTTATATGCACTG
>TCONS_00060631
TCTCTTCCGCCTCCGTGATCCTCAATGATCTGTAATCCGAAAGAAGATGGCCAAATCCACTAACAGACTGTCGGAGGTCTAATCCGATTCGCTGTCGGTTGATGAAACCTCAGCTGTGCTCAAAGCTGCTAATGTATGGGGAGCTTTGCGAGgACTGGAAACATTCAGCCAGTTGGTCTATGAGGATGACTATGGAGTTAGAAATATTAATAAGACCGACATATCAGATTTTCCACGGTTTGCCCACCGAGGAATCCTTCTGGACTCGTCTCGCCATTTTCTGCCACTCAAAGTCATTTTGGCCAACTTGgaagcTATGGCCATGAACAAGTTTAACGTCTTCCACTGGCACATTGTGGATGATCCGTCGTTTCCTTTTATGAGCCGTACTTTCCCAGAGTTGAGCCAAAAGGGAGCCTATCACCCATTTACACATGTGTACACTCCATCTGATGTGAAGATGGTCATTGAATTTGCTCGCATGAGGGGGATCAGGGTCGTTGCGGAGTTCGACACCCCAGGGCACACGCAGTCATGGGGCAATGGCATAAAGGATCTGCTAACACCTTGTTACAGTGGCTCTAGTCCTTCAGGATCATTTGGGCCCGTGAACCCCATCTTAAACTCCTCTTATGAGTTCATGGCACAGCTTTTCAAAGAGATCAGCACCGTCTTTCCTGACGCTTACATTCACCTAGGGGGAGATGAGGTCGACTTTTCTTGTTGGAAGTCCAATCCTGATATTCAGAAGTTTATGAATCAGCAAGGCTTTGGCACAGACTACAGCAAACTGGAGTCCTTCTACATTCAAAGGTTACTTGATATTGTGGCTGCTACCAAAAAAGGTTACATGGTGTGGCAGGAGGTGTTTGATAACGGGGTCAAGCTGAAAGCCGACACACAGATCCATGTGTGGAAAGGCAGGCCG
>TCONS_00060632
acacacacgaacaGTCCTCCGCTCAGACTGGAAGCAGAGTCAGTCAGCTGACCGCTCAACACAACCATGCTCTGTCTGCTCAAGTTTACCCCTCTGTTTTTGGTGGTAGCCGTATGTCACGGCTGGCTTTTTGGAGATCTTTTTGAAAAACAGAAAGAGCTGGATGAAATCTCTCTATGGCCTCTACCGCAGAAATACCAGTCGTCCGCGGTCGCTTTTAAACTCAGCGCCGCCAGCTTTCAAATCGTCCACGCCAAACAGTCCACCGCCGGACCGAGCTGCAGTCTACTCGAGAATGCATTTCGCAGATATTTTGAATACATGTTTGGAGAGCTGAAAAGGCAGGAGAAAAGCCGAAAGAAAGCGTTTGATTCAGATCTCTCGGAGCTGCAGGTATGGATCACATCAGCTGATCCGGAGTGCGACGGTTACCCGAGTCTTCGAACCGACGAGTCATATTCGCTGTCGGTTGATGAAACCTCAGCTGTGCTCAAAGCTGCTAATGTATGGGGAGCTTTGCGAGgACTGGAAACATTCAGCCAGTTGGTCTATGAGGATGACTATGGAGTTAGAAATATTAATAAGACCGACATATCAGATTTTCCACGGTTTGCCCACCGAGGAATCCTTCTGGACTCGTCTCGCCATTTTCTGCCACTCAAAGTCATTTTGGCCAACTTGgaagcTATGGCCATGAACAAGTTTAACGTCTTCCACTGGCACATTGTGGATGATCCGTCGTTTCCTTTTATGAGCCGTACTTTCCCAGAGTTGAGCCAAAAGGGAGCCTATCACCCATTTACACATGTGTACACTCCATCTGATGTGAAGATGGTCATTGAATTTGCTCGCATGAGGGGGATCAGGGTCGTTGCGGAGTTCGACACCCCAGGGCACACGCAGTCATGGGGCAATGGCATAAAGGATCTGCTAACACCTTGTTACAGTGGCTCTAGTCCTTCAGGATCATTTGGGCCCGTGAACCCCATCTTAAACTCCTCTTATGAGTTCATGGCACAGCTTTTCAAAGAGATCAGCACCGTCTTTCCTGACGCTTACATTCACCTAGGGGGAGATGAGGTCGACTTTTCTTGTTGGAAGTCCAATCCTGATATTCAGAAGTTTATGAATCAGCAAGGCTTTGGCACAGACTACAGCAAACTGGAGTCCTTCTACATTCAAAGGTTACTTGATATTGTGGCTGCTACCAAAAAAGGTTACATGGTGTGGCAGGAGGTGTTTGATAACGGGGTCAAGCTAAAGGATGACACTGTTGTGGAGGTGTGGAAAGGGAACGATATGAAGGAGGAGCTCCAGAATGTGACTGGGGCAGGATTTACAACCATTCTTTCTGCCCCTTGGTACCTGGACTACATTAGCTATGGACAGGACTGGCAACGCTACTACAAAGTTGAGCCACTTGATTTCACTGGTCAGTTTCTTCAGTCAAACTCTTTTTGATTTCTTTTAGCACCACTAGCATAGTGTTTAGTAATCCAGTGATGTCAAAATCACTCGTTTATTGAATTTAGCAGTTTTGTGTGATGGATATGATGTGTTGTTGGCTTATTCTTAACTTGGGGGTTAAGAATATCGGTTTAGACTCTAcagttttaatcaaataaagaTCCTTCAATAGGTT

Function


symbol description
hexb Enables hexosaminidase activity. Acts upstream of or within angiogenesis. Predicted to be located in lysosome. Used to study lysosomal storage disease. Human ortholog(s) of this gene implicated in Sandhoff disease and spinal muscular atrophy. Orthologous to human HEXB (hexosaminidase subunit beta).

GO:

id name namespace
GO:0008152 metabolic process biological_process
GO:0001525 angiogenesis biological_process
GO:0005975 carbohydrate metabolic process biological_process
GO:0004553 hydrolase activity, hydrolyzing O-glycosyl compounds molecular_function
GO:0004563 beta-N-acetylhexosaminidase activity molecular_function
GO:0016787 hydrolase activity molecular_function
GO:0016798 hydrolase activity, acting on glycosyl bonds molecular_function
GO:0015929 hexosaminidase activity molecular_function
GO:0102148 N-acetyl-beta-D-galactosaminidase activity molecular_function

KEGG: NA

ZFIN:

id description
ZDB-GENE-030131-2333 Enables hexosaminidase activity. Acts upstream of or within angiogenesis. Predicted to be located in lysosome. Used to study lysosomal storage disease. Human ortholog(s) of this gene implicated in Sandhoff disease and spinal muscular atrophy. Orthologous to human HEXB (hexosaminidase subunit beta).

Ensembl:

ensembl_id ENSDARG00000034368

RNA


RNA id representative length rna type GC content exon number start site end site
TCONS_00060629 False 2024 mRNA 0.46 14 34600714 34616599
TCONS_00060630 False 955 mRNA 0.50 8 34600930 34609337
TCONS_00060631 False 928 processed_transcript 0.48 10 34603814 34615966
TCONS_00060632 True 1642 mRNA 0.46 11 34605797 34616599

Neighbor


gene id symbol gene type direction distance location
XLOC_031218 BX296533.1 coding downstream 362691 34237907 ~ 34238023 (-)
XLOC_031217 fibcd1 coding downstream 415217 34066591 ~ 34185497 (-)
XLOC_031216 zgc:63972 coding downstream 640846 33940215 ~ 33959868 (-)
XLOC_031215 si:dkeyp-72a4.1 coding downstream 665318 33879807 ~ 33935396 (-)
XLOC_031214 dab2ipb coding downstream 714219 33679559 ~ 33886495 (-)
XLOC_031220 arhgef28a coding upstream 211015 34827614 ~ 34964830 (-)
XLOC_031221 BX530075.3 coding upstream 217379 34833978 ~ 34834093 (-)
XLOC_031222 btf3 coding upstream 370849 34987448 ~ 34997630 (-)
XLOC_031223 tmem174 coding upstream 488486 35105085 ~ 35108893 (-)
XLOC_031224 fcho2 coding upstream 507063 35123662 ~ 35201482 (-)
XLOC_031210 NA non-coding downstream 1314056 33286587 ~ 33286658 (-)
XLOC_031209 CU019641.3 non-coding downstream 1315117 33285526 ~ 33285597 (-)
XLOC_031200 NA non-coding downstream 1672795 32922656 ~ 32927919 (-)
XLOC_031198 NA non-coding downstream 1714840 32885179 ~ 32885874 (-)
XLOC_031229 NA non-coding upstream 906810 35523409 ~ 35540980 (-)
XLOC_031231 BX005476.1 non-coding upstream 1206819 35823418 ~ 35823548 (-)
XLOC_031238 NA non-coding upstream 2205275 36821874 ~ 36829073 (-)
XLOC_031240 NA non-coding upstream 2286547 36903146 ~ 36907379 (-)

Expression



Co-expression Network


Homologous


species gene id symbol gene type chromosome NCBI id location
grasscarp (Ctenopharyngodon idella) CI01000071_00316661_00326675 HEXB coding CI01000071 null 316661 ~ 326814 (-)