XLOC_003145 (tp53rk)



Basic Information


Item Value
gene id XLOC_003145
gene name tp53rk
gene type coding
species zebrafish (Danio rerio)
category of species model fish

Chromosome Information


Item Value
chromosome id NC_007122.7
NCBI id CM002895.2
chromosome length 45484837
location 2458264 ~ 2466879 (+)
genome version GRCz11_2017_zebrafish_Genome

Sequence


>TCONS_00006207
ATGGCTCAAACAGACTCAGCAAAAGCGGCTGTCCCGTCCTATTTAAAAGAGGCGCAGATGATTAAACAGGGCGCTGAGGCTCGGGTCTATCGAAGCACATTTTTGGGTCGCTCTGTGATTATTAAGGAGAGATTTCCCAAGTTATACCGCCATCCGGAAGTGGATGAGAAACTGACGCGCCGCAGAACAACACAGGAGGTGCGCTCCATACTGCGCTGCAGGAGAGCCGGCATCAGCGCACCGGTTGTGTATTTTGTGGACTACGCCACACACTGCATCTTCCTGCAGGACGTGGTGAACTCTGTGTCAGTGCGAGACCACATCAGATCGCAGCCGGACGGTCTGCAGACTCTGGCGGAGCGCATCGGTGAAGTTCTGGCTCAGATGCACGATGAAGACGTCATTCACGGAGATCTGACCACCTCCAACATGCTGCTGACCAGCGGAGGACAACAGCAAGACTTCAACCTGGTGCTCATCGACTTCGGCTTGAGCTACATCTCCGCTCTTCCTGAGGATAAAGGAGTGGATCTGTACGTCTTGGAGAAAGCTTTTCTCAGCACTCACCCCAAAACTGAGGCTTTATTCGAGAGGCTTCTGAAGAGCTACAGCAGTGCCTCTAAGAAGTCCACTGCGGTCATCAAGAAACTGGACGAAGTTCGGCTGAGAGGACGCAAGAGGTCAATGGTGGGATAGCAGTAAAGTGGTTTCAATCATTCAGGCTTAAAGGATTCGTTCATTTGCTGAATAAAAATTTCCACCATCGAAGACtctgtttcccaaccctgttcccgaAGGCACAGCAACAGAACATTTTTGATCtcaacctaatcaaacacacctgaatcaactcatcagaagaTTAGAAAAGACCCCAAAAACCTGgagttaatgggtcagataagggagacatggaaaatatgtactgttggtgtgcctccaggaacagggttgggaaacactgatctaaGATAACTGgtcaaactaaaattaaaaagtactcactatttttactcaaaaaaataagtttgctgtttgttcaaactacttatttcgCTGAAACTACACAATTCTCAAGtgattttttgggacaacttcattTGCGTCctgaataaaaatgttcatcGTCATCTAagacagtgtttcccaaccctgttcctggagacacaccaacagtacatattttggatgtctcccttatctgaaaCATTAACTTCAGAAGGTTTTATGCAAGTACGAGTAAATAGTGCTGAATGTAGATTTTTGAGTGAGCAATAGGTttaatttcttttcagctaaaaaaaataatgaaattaacatCTTTGATGCCTGGAGTAACGAACTtaaaacatattttggatgtGAACTAATCCCTGCAGTTTGATGTTGGACATTTATAAAGGTGTATTTCTTTATTGTAATGAATTTCGATTTCTAACATGTTGGTTAAACAGTGTTTTTGTGCTCATTTTAGTGTTTCTTCTGAATGGAAGTCGAGTTAAACTAAATGTAGtttaaaataaactgttgaaCCCTATTAACATGCATGAGATGTATTTCTCGCTGCATATGCAACCAATAAAGAACTGGCTTCAGAATATTGCTGGAATGTGTGTTTaatcagtaataaataaaacatgcactcactggccactttattaggtacaccgtactagtaccaggttggacccccttttgtcttcagatctgccttaatccttcatggcagagattcaacaagctactggaaatattcctcagagattttgctccatgttgacatgatagcatcacgcagttgctgcagatttgtcagctgcacatccatgatgtgaatctcgtttcaccacatcccaaagctgctctattggattgagaacaggtgactgtggaggccatttgagtacaatgaactcttcaagaaaccagtctgagatgattcacgctttatgacatgcgttatcctgctggaagtagccatcagaagatggagacactgtgctcataaagggatggacatggtcagcaacaatactcaggtaggctgtggcgttgacacgatgctcaattggtactaaatctgacccaaagtgtgccaagaaaatctcccccacaccattacacctccaccaccggtctaaaccattgatacaaggcaggatggattcatgcttgcATGTAGTTGACACCAAACTTTGACCCGACcgtccgaatgtgtcagcagataTCGAGCctcatcagaccaagcaacgtttctccaatcttctattgtccagttttggtgagcctgtgtgaattgtaggtTGGAGGTGTtgtttgttcagagatgctcttctgcagacctcgattATAACGAGTGGTTTGAGCtgctgttgtctttctatcagctggaaccagtctggccattctcctctggcatcaagacattttgcgcccacagaactgtcgctcactggatattcccCTCGGTTATGTGCACACACTGCAACActactgtgtttaaacctcttaaatggttaaacactttaaattaaatgacacttttttttttttttaagccagGGGTTGTCTTTGTCGATAACACAGAGCTAAAATAGCACAGCATTTATTTAAGTGTGTGCTTTTAtttcacaataaaaatattaacaaaacaaaacatgcattaAGAACACAAAGATCAGTGCATTTTACCTCTAActtaaatacataatataaaaaaagtctCACGTAGCAGTAAGCTGAAATAAACGAAATATAAAATCCATAAACATTTCTACTGATGGCACAGAGAAGATGCTAATCTCATGCTGAACTTAGTAGGCAAAACGGTCCAAAATCAAACGTATTGGAAAAAGTGACTCACGTATCGTGTAAGGAGTCCTAGattgcaaataaaacacaaaaggaAACGTCTGTTAATGAAGCCTGAACAAAAGATGTGTTCAAAAAGTCCTGAGGTCACGTGAAGTCTCTGTTGGGGAGGATCATGGGAGCGATCAGACTCCAGGTGTATAAAGTGAGACAGACCCAGCTGGAGGAGATCTTGACCCACACCGCCGGCCACTTACTCCTCATGGCGTTGTAGTCTGTGTCAGGACTGTGTTCACAATCAAGTGAATTAGAAACAAGATCTTAAACCTGCTGCTGAACTCATGTCTACTGATGTACGTCTGTTTAGTGGAAGCCTGTttgtgattgttttgttttttttgagtttacatctcacaGTTGTGCAAAATAAAATGCTGAATTGTGAAGCGATcaagtcttaaattttaaaatgaaaactctgaATTTTGACAAAGAGTAATGCTGGAAACTTACAGCAGGGAAATTGAGTGTTGAACATTcatctaaaggagctgttgacatggagttGAAGCAGAGTTTGGTGGAAACCCaaacaatataaacataaaaattaaaaatgagatCTGTGTAATAACAAAATGACACAAGAAGAAAGTGCTGAActtctgaaatgtgtttaatactttatataaaagcctaaagacgcctctcatataaAGAATAAAGTCatatgcattgctcaggtgtgagtttctcacagacttcaacagagtgtcaaaatcttgatgcttctgtgggtctcgtctatcaaatctgagctatattctgtattctctattgaattcagctcaggtgattggctgggccattccacagcttgattttcattctctgaaagcatctgagagtctccttggctgtgttttggatcattgtcttgctgaaatgtccaccctggtttcatcttcatcctcctgctaatgtagatgttggactgaagcagctgatcttcatttacactgaggaagggcagaggcttgctgaagaaccactgagagatttcagttgctgtctgggctttcactgccgaactacacctccctttcttcatctgTTTAATACTAATTCTCTGTCTCATgtcattttattacgcataacttcatttgcacactaattagatttgtttgcatttatagatttctttggttgtCTCCAACATCCACAATTTCAAgtaaacagcacctttagaaatgtgttttctgagaGAAATGgcgatgtgttcaatacttatttcccctacTGTAACTCAAAAGTGTCATGCAAATGTGCAATTCTGACCAATTTCAAGCCAGTTTAAATCATTTAAGCAGAGGAAACTACAatttataaaagattaaaatcacatgtaaaaaataaaaataaaagtttttacattgaattattattaaaaaggaaaaccataaagtatttatttcatttgtaccTTTGTTCTACAGTATTTATCAATGCTTATTATTGGTTTATTGCATTTTACGCAGATGAACTCCACACCAAAATCAGCCTGATCAATCTAAAATAAGGAATTCTttacaaatagagctattcatttCATCATGGTCAAATTACACTcaatatacagtcgaagtcaaaaTTAATCGCCCCcttgtgaattttcttttctgtttcaaatatttcctaaatgatgttgaacagattcaggaatttttcacagtattttctataatattttttcttctgggaaaaagtcttatttgatttatttcagctagaataaaagcagttcttaattttattgaaaccatttaaggtcaaaattattagccccccttaatctATATTTGTTTcggattgtctccagaataaaccgCTGTAATACAATGGCTTGCCGAATTACCCTAAATTTAccctacttaacctagttaaaactttaaatgtcactttaagctgaatactagtgtctttaaaaatatctagtctaatattatttactgtcatcatgacaaagacaaaataaatcagttattaaaatgagctattaaatctattagaaaatctgctctccgttaaacagcagtttgggaaaaaataaacaattaattctgacttcaactgtatatcgcagaaaaataaaacatcgcAGCTGTTTCCAGTATTGTAGAGGTTTGTGTGGTCACTCACCTGTACCAGTTGGTGAGCGTCATCATGATGTAAAGAGACGCCAGGAACAGCATGAAGTGGAAGAAAGCGTAGCTGTACTGAACCGTCTCTCGCTCATTATCTTCCATATGATGTGCTGTGGTGTTTTCTTCTGCCGCCTCTGCACTGCTTGCGGCACTTTCATCCTGAACCGTGGCATCTTTAGCCGCTAAGGTTAATTTATTCACTTGACTAGTATTGGAAGAGCGAATGCTGCCAAGAAAACATAGAAACAAAAGAGTCTCTTTATATTAAGTAGACAATACA

Function


symbol description
tp53rk Predicted to enable protein serine/threonine kinase activity. Predicted to be involved in protein phosphorylation and tRNA threonylcarbamoyladenosine metabolic process. Predicted to act upstream of or within phosphorylation and tRNA processing. Predicted to be part of EKC/KEOPS complex. Predicted to be active in nucleus. Human ortholog(s) of this gene implicated in Galloway-Mowat syndrome 4. Orthologous to human TP53RK (TP53 regulating kinase).

GO:

id name namespace
GO:0070525 tRNA threonylcarbamoyladenosine metabolic process biological_process
GO:0006468 protein phosphorylation biological_process
GO:0000408 EKC/KEOPS complex cellular_component
GO:0005634 nucleus cellular_component
GO:0005524 ATP binding molecular_function
GO:0004672 protein kinase activity molecular_function
GO:0004674 protein serine/threonine kinase activity molecular_function

KEGG:

id description
ko01001 Protein kinases
ko03016 Transfer RNA biogenesis

ZFIN:

id description
ZDB-GENE-050522-123 Predicted to enable protein serine/threonine kinase activity. Predicted to be involved in protein phosphorylation and tRNA threonylcarbamoyladenosine metabolic process. Predicted to act upstream of or within phosphorylation and tRNA processing. Predicted to be part of EKC/KEOPS complex. Predicted to be active in nucleus. Human ortholog(s) of this gene implicated in Galloway-Mowat syndrome 4. Orthologous to human TP53RK (TP53 regulating kinase).

Ensembl:

ensembl_id ENSDARG00000112667

RNA


RNA id representative length rna type GC content exon number start site end site
TCONS_00006207 True 5295 mRNA 0.39 2 2458264 2466879

Neighbor


gene id symbol gene type direction distance location
XLOC_003144 csnk2a4 coding upstream 11918 2434262 ~ 2446346 (+)
XLOC_003143 ube2v1 coding upstream 28961 2416064 ~ 2429303 (+)
XLOC_003142 pip4k2cb coding upstream 45157 2398843 ~ 2413107 (+)
XLOC_003141 igfbp6a coding upstream 60290 2391469 ~ 2397974 (+)
XLOC_003140 NA coding upstream 137909 2308209 ~ 2320355 (+)
XLOC_003146 NABP2 coding downstream 39637 2506516 ~ 2513093 (+)
XLOC_003147 zgc:113184 coding downstream 87977 2554856 ~ 2566692 (+)
XLOC_003148 dnajc14 coding downstream 129788 2596667 ~ 2609824 (+)
XLOC_003149 FQ790208.1 coding downstream 148191 2615070 ~ 2616023 (+)
XLOC_003150 si:ch211-160o17.3 coding downstream 166864 2633743 ~ 2649496 (+)
XLOC_003250 BX324177.11 misc downstream 8878924 11345803 ~ 11346099 (+)
XLOC_003255 BX324177.14 misc downstream 8906007 11372886 ~ 11373182 (+)
XLOC_003257 BX324177.13 misc downstream 8919483 11386362 ~ 11386658 (+)
XLOC_003260 BX324177.2 misc downstream 8951154 11418033 ~ 11418323 (+)
XLOC_003262 BX324177.15 misc downstream 8962514 11429393 ~ 11429689 (+)
XLOC_003139 NA non-coding upstream 252466 2198530 ~ 2205798 (+)
XLOC_003138 mir196c non-coding upstream 267534 2190621 ~ 2190730 (+)
XLOC_003132 NA non-coding upstream 460854 1935684 ~ 1997410 (+)
XLOC_003156 CT583672.1 non-coding downstream 360674 2827553 ~ 2828675 (+)
XLOC_003159 dre-mir-724 non-coding downstream 709807 3176686 ~ 3176770 (+)
XLOC_003160 NA non-coding downstream 736608 3203487 ~ 3206698 (+)
XLOC_003164 NA non-coding downstream 864234 3331113 ~ 3333714 (+)

Expression



Co-expression Network