LOC110490651 (apex1)


Basic Information

Item Value
gene id LOC110490651
gene name apex1
gene type coding
species rainbow trout (Oncorhynchus mykiss)
category of species economic fish

Chromosome Information

Item Value
chromosome id NC_048579.1
NCBI id CM023233.2
chromosome length 81569517
location 70547485 ~ 70550529 (+)
genome version USDA_OmykA_1.1_2020_rainbow_trout_Genome

Sequence

>XM_036945186.1
TCACGGATTCAGGGGAAAATCACATCAGGCATAATATAGGGCAGCCTACaccacatgcgtgtgtgtgtgaccatgttCCTCAAACCCCACTGCTTTGTTTTGGAGGAGTGACTGTGCGACTGTGACACGTTTGAATCCTTTGTTGTGAAAACGCAAACGGCGACGCGTGTGTACTcgtgtgtgcgtgttgtgtgtCTTCGGGGCGTGTGTGGGATAAGAACGAGTGAAAGTATGTCGAAAAGAGCGAAGAAAAATGAGCAGGAGGCTGGAGATGGTGACCATGACAACGGCACAGCTCCCGCTGCCAAGAAAGGAAAGAAGGTCAAGGAACCAGAGGCTCCCATTCTGTACAGTGACCCTCCTGATAAGATGAACAGCAAAGATGGTCGTGCTGCTAATATGAAGATCACCTCCTGGAATGTGGATGGGCTCAGAGCTTGGGTCAAGAAGAAGGGCCTTGATTGGGTGCGTGACGAGGCCCCAGATGTGCTGTGCCTGCAGGAGACGAAGTGCGCTGAGAAGTCCCTTCCTGATGAAATCACCTCCATGCCTGAGTTCCCCCACAAGTACTGGGCTGGCTCTGATGAGAAGGAGGGCTATAGCGGGGTAGCTATGCTGTGCAAGACTGAGCCCCTCAAAGTTACCTATGGCATAGGTAAAGAGGAGCATGATAAGGAGGGCCGTGTTATCACTGCTGAGTTCCCCACCTTCTTCCTGGTCACCGCCTACGTGCCCAACTCTGGCCGAGGCCTGGTGCGCCTGGACTATCGCAAGACCTGGGACGTGGAGTTCAAGGCCTACCTGAGCGACCTGGACAAGCGCAAGCCCCTGGTGCTGTGTGGCGATCTGAACGTGGCCCACGAGGAGATCGACCTGAAGAACTCCAAAGGCAATAAAAAAAACGCAGGCTTCACAGCAGAGGAGCGTGAGGGCTTCAATCAGCTGCTGGCTGCAGGCTTCACCGACAGCTTCCGCGAGCTGTACCCCGAGCAGGCCAATGCGTACACCTTCTGGACCTACATGATGAACTCTCGCTCTAAGAACGTAGGCTGGCGTCTGGACTACTTTGTGCTGTCCTCTGCTCTACTGCCAGGCCTTTGTGATAGCAAGATCCGCAACCAAGCTATGGGCAGTGACCACTGCCCCATCACTCTGCACATGGTTGTGTAGATCAGTCTGGCCAAAGTGCTGGATCAATTGTTTCCCAGTTCAATAGTTTTGGCAGTGTGGCCATGCATTGTTTTCTCATGTTAAATGTGACCTAGGTGGCGGACCTCAGATGAAGTCATGGCATTCCCAACTACTGAAACTAATCTGTATGCCGGTGTGCACACTCAACATGAGTGAAACATCAGAACCTGGAAACACGTTTCTACTGAAACTGGGATTCTCAAGAGTTTACGTAACCCTCAAATCTTAAATTGTATAAACTACCGTAGTCACAATTGTCCTGTCACCCATTTGAAGTGACTATTCAACACTGCTTTACTTTCCCACCCACACAATGCACTCCTAAGTGACATCTGGTAACATACGGCATAATCCCTGCAAGTCCTCTGAGGCAGTGTTCTTTAAACATGTGAAACTGATGCTCAATAACTGCTAGTCTGTCATTGAAACATTGCTCCTTTGAAGGGAATGTGAGTCCTATTTTGTTAATTAATATTATATATAATGGTAATGAAGTCATTACCATTGAGTGAATATTGATAAATTAAATCATGGTACAGATTTATTAGCATGCAAACATTCAGACCCAGATTGATGACCAGTATTAAGATTGTCAAATGGTTCAACCTCTAGAGCTGATATGAGACCAATGTCAGTGGTATCTCACCCCTTACTGCCAATGTCCGGAGCAAAGTTTCTAAGACATGCCTgttttgtattaaaaaaaaatcccaaaccATAGCTTGAGTTTATAGATGGTAAATATACCCATGCATCTAATAAAGTTTAGTTTTAAGTATG

Function

symbol description
apex1 Predicted to enable DNA-(apurinic or apyrimidinic site) endonuclease activity; double-stranded DNA 3'-5' exodeoxyribonuclease activity; and phosphodiesterase I activity. Acts upstream of or within several processes, including heart contraction; heart looping; and negative regulation of apoptotic process. Predicted to be located in endoplasmic reticulum; mitochondrion; and nuclear lumen. Predicted to be active in nucleus. Is expressed in head. Human ortholog(s) of this gene implicated in breast cancer; female reproductive organ cancer (multiple); spina bifida; and urinary bladder cancer. Orthologous to human APEX1 (apurinic/apyrimidinic endodeoxyribonuclease 1).

NR:

description
DNA-(apurinic or apyrimidinic site) lyase

GO:

id name namespace
GO:0090305 nucleic acid phosphodiester bond hydrolysis biological_process
GO:0006281 DNA repair biological_process
GO:0005622 intracellular anatomical structure cellular_component
GO:0004519 endonuclease activity molecular_function
GO:0003677 DNA binding molecular_function
GO:0016829 lyase activity molecular_function

KEGG:

id description
K10771 APEX1; AP endonuclease 1

RNA

RNA id representative length rna type GC content exon number start site end site
XM_036945186.1 True 1971 mRNA 0.48 5 70547485 70550529

Neighbor

gene id symbol gene type direction distance location
LOC110490654 LOC106576592 coding upstream 4651 70538862 ~ 70542834 (+)
LOC110490656 LOC106576586 coding upstream 8523 70528555 ~ 70538962 (+)
LOC110490638 LOC106609738 coding upstream 19657 70523460 ~ 70527828 (+)
nav3 LOC106609740 coding upstream 29270 70276077 ~ 70518215 (+)
LOC110490865 fel coding upstream 545436 69999844 ~ 70002049 (+)
LOC110490670 NA coding downstream 15372 70565742 ~ 70569724 (+)
LOC118938837 LOC106576594 coding downstream 98503 70649032 ~ 70653883 (+)
LOC110490812 LOC106576598 coding downstream 326615 70877144 ~ 71062055 (+)
LOC110490701 LOC106609709 coding downstream 606512 71157041 ~ 71158063 (+)
LOC110490712 nel coding downstream 744896 71295425 ~ 71400412 (+)
G1322601 NA non-coding upstream 24171 70522133 ~ 70523314 (+)
G1322596 NA non-coding upstream 50794 70496442 ~ 70496691 (+)
G1322595 NA non-coding upstream 52691 70494589 ~ 70494794 (+)
G1322592 NA non-coding upstream 55253 70491882 ~ 70492232 (+)
G1322587 NA non-coding upstream 73879 70473254 ~ 70473606 (+)
G1322407 LOC106576585 non-coding downstream 3303 70553832 ~ 70554417 (+)
G1322613 NA non-coding downstream 14071 70564600 ~ 70565042 (+)
G1322617 NA non-coding downstream 19702 70570231 ~ 70570450 (+)
G1322618 NA non-coding downstream 20321 70570850 ~ 70571051 (+)
G1322161 NA other upstream 643827 69900944 ~ 69903658 (+)
G1322119 NA other upstream 747623 69798196 ~ 69799862 (+)
G1321053 NA other upstream 1751504 68794598 ~ 68795981 (+)
G1320834 NA other upstream 2260217 68285896 ~ 68287268 (+)
G1320366 NA other upstream 3003004 67544041 ~ 67544481 (+)
G1322725 NA other downstream 293416 70843945 ~ 70847944 (+)
G1322763 NA other downstream 385696 70936225 ~ 70937145 (+)
G1323962 NA other downstream 1639894 72190423 ~ 72191163 (+)
LOC110531894 LOC106598741 other downstream 1905688 72416050 ~ 72481441 (+)
LOC110490361 LOC106609821 other downstream 2191684 72742193 ~ 72850175 (+)

Expression


Co-expression Network