XLOC_031653 (ephb4a)


Basic Information

Item Value
gene id XLOC_031653
gene name ephb4a
gene type coding
species zebrafish (Danio rerio)
category of species model fish

Chromosome Information

Item Value
chromosome id NC_007116.7
NCBI id CM002889.2
chromosome length 72500376
location 68408346 ~ 68495967 (-)
genome version GRCz11_2017_zebrafish_Genome

Sequence

>TCONS_00061300
TCCTGATGAACACGAAAACGGAGACATCAGATCTGAAGTGGACGACACACTCTCGCTCTAAACCTGAGTGGGAGGAGGTCAGTGGTCTGGATGAGGAGAACAACAGTGTGCGGACCTATCAGATCTGCCAGGCGGACGGCTCCAGCAGTCATTGGCTGCGTAGTAAGCTGATCGAGCGGCGGGGGGCGTCACAGGTGTACGTGGAGCTGTTCTTCACTATGGTTGAGTGTTCATCTCGAAACACACACCACCGCTCCTGCAAAGAGACTTTCAACCTTTATTACTACCAAAGCGACACGGATGACGCCACAGCCACCCACCCGGCGTGGATGGAGAACCCCTACACCAAGGTGGACACAGTGGCCGCAGACTTCCTACTGCGCAAAGGCGGAGAGAAGAAAGTCAACGTGAAGACGCTGCGTTTGGGCCCGTTGAGCAAGCGTGGATTCTACCTGGCGTTTCAGGCTCAGGGCGCGTGCATGGCTCTGCTCTCCGTGCGTGTTTTCTTCAAGAAGTGTCCGGCGCTCACGCGCTCACTATCCGTCTTCCCGGAGACCGTTCCCCGCTCGCTGGTCCAGGAGGCAGTGGGCCAGTGTGTGGCCAACGCAGCACAGCCTGGCCCCAGTCCCAGACCGCCCAAGATGTTCTGCGGAGAAGATGGACAGTGGGTGGACCAGCCCACCACCACCTGCACTTGCCTGCCGGGCTTCGAGGCCAGCCATGGAGAGCTGGAGTGTAGAGcgTGTCCTGTGGGTCTGTTCAAGATGGGTTCTGGTACCGGTCCGTGTTCTGTGTGTCCTGAGAACAGTCAGACGGGAGAGACGGGTTCTGCTGCATGTGTGTGCCGCTCTGGGTTTTATCGCGCTCTGAGTGACAGTGCAGATACACCCTGCACACGTCCTCCGTCGTCTCCGCGCAGCCCCGTCCCGCAAGTAAACGACACATCTCTGACTCTGGAGTGGAGCGAGCCGTTGGACAGCGGCGGCCGCTCGGATCTCAGCTACAGCGTGGAGTGTAGGATGTGCTCCACCCCTGGAAGTCCCTGCACACTATGCAGTGACGGTGTGAATTATCGGCCGTCCCAAACAGGGATCCAAGGCCGGCGCGTGAGCATTTGGGGTCTGAGACCTCACACCACCTACAGCTTCACTGTCATGGCCCTCAACGGGGTCTCCGCTCAGAGTCAGCAGGGGCCTGCAGGAGAGACCATCAACATCACCACCAGTCCCAATGTTCCTGTGTTGGTTTCGGGCTTGAGGAAGAGCACAGCCACTGAATCCAGCCTGACGCTGTACTGGAACACACCCACCCAGTCACACTACAGGATCCTGCAGTACCAGATACGCTACTGCGAGAAGGAGCGCGGATCTGAAGAAAACTCCTGTCATTATATGGAGAGCAATAACAACGAGGTGGTTTTGAGCGACTTGCGAAGGGCCACGCAGTATGAGGTTCAAGTCCGAGCTCGGACATTCGCCGGATATGGAAGCTTTGGTAAAGCCATCCTCTTTCGAACTCTACCTGACGAAGATGATTCCTCGTCTCCCCTGCTTGTTACTGGGATCCTGATAGCCATGGGGATGCTGCTCCTCATCATCGTCATTGGGGCGGCCATTTATTGCATAAGGAAGCAAAATAACTACAAAGATCCAGAGCTGAGCGACAAAAACGGACAATATCTCATGGGTCAAGGAGTGAAGGTCTACATCGATCCCTTCACTTATGAAGACCCTAATGAGGCCGTGAGAGAGTTTGCTAAAGAGATCGATGTCTCGTGTGTCAAAATCGAGGAGGTTATTGGGGCAGGTGAGTTTGGGGAAGTGTGTCGGGGACGACTGAGGATTCCGGGTAAGAAGGAGAACTATGTGGCCATCAAGACCCTGAAGGGTGGATATACAGACAAGCAAAGGAGGGACTTCCTGGCTGAGGCCTCCATCATGGGCCAGTTCCAGCACCCCAACATTATTCACCTGGAGGGCATAATAACAGCAAGCTGCCCCGTCATGATCCTCACCGAATTCATGGAGAACGGAGCTCTGGACTCTTTCCTCAGACTCAACGATGGACAGTTTACACCGATACAGTTAGTCGGGATGCTGCGGGGCATTGCATCAGGAATGAAATATCTCTCAGAAATGAGTTACGTACACCGAGATCTTGCAGCGCGCAACATTCTTGTGAACAGTAACCTGGTCTGCAAGGTGTCCGACTTTGGTCTGTCGAGATTCCTGCAGGAGAATTCATCGGATCCCACGTACACCAGCTCACTGGGTGGTAAAATTCCCATCCGCTGGACGGCACCCGAAGCTATCGCCTTCCGTAAATTCACCTGCGCGTCCGATGTGTGGAGTTACGGGATTGTCATGTGGGAAGTGATGTCGTTTGGAGAACGACCGTACTGGGACATGAGCAACCAGGATGTGATTAATGCCATTGAGCAGGATTACCGTCTGCCACCGCCGCCGGACTGTCCCACATACTTGCaccagctgatgctggactgctGGCAGAAGGAGAGGACGGCCCGGCCACGCTTCGCCAACATCGTCTCAGCTCTGGACAAGCTGATCCGCAACCCGGCCTCACTCAAAATCACAGCGCAGGAGGGGGCGGGCCCCTCTCACCCTCTGCTGGACCAGCGGTCTCCACTCACGCCCTCATCCTGCGGGACAGTGGGTGACTGGCTGCGGGCCATCAAGATGGAGCGCTACGAGGAGACATTTCTGCAGGCGGGATACACGTCCATGCAGCTCGTCACCCACATCAACACGGAGGATCTGCTGCGTTTGGGAATAACTTTAGCAGGTCACCAGAAGAAGATTCTCTCCAGCATTGAGGCTCTCGGGATTCAAAACAAAGCACCAGGGAATGTGCTGTACTGagtgaaccacacacacacacacacacacacacacacacacatatgaactcTACAGTGCT
>TCONS_00061301
GGTACAACAAGACCCAGCTGACGACTCTTGAACCTTTACACTGTTTACCCACCTTTGTAAACATTCACAAGTAAAACACTCGTGATTCCGCGATGGAGCTCTTCTCCAGGAATGTGGCCGCGTTTTGGATTATCCTGCTGGAGTTCCTGCTCGGATCAGTGGCGGAGGAAGAAGTCCTGATGAACACGAAAACGGAGACATCAGATCTGAAGTGGACGACACACTCTCGCTCTAAACCTGAGTGGGAGGAGGTCAGTGGTCTGGATGAGGAGAACAACAGTGTGCGGACCTATCAGATCTGCCAGGCGGACGGCTCCAGCAGTCATTGGCTGCGTAGTAAGCTGATCGAGCGGCGGGGGGCGTCACAGGTGTACGTGGAGCTGTTCTTCACTATGGTTGAGTGTTCATCTCGAAACACACACCACCGCTCCTGCAAAGAGACTTTCAACCTTTATTACTACCAAAGCGACACGGATGACGCCACAGCCACCCACCCGGCGTGGATGGAGAACCCCTACACCAAGGTGGACACAGTGGCCGCAGACTTCCTACTGCGCAAAGGCGGAGAGAAGAAAGTCAACGTGAAGACGCTGCGTTTGGGCCCGTTGAGCAAGCGTGGATTCTACCTGGCGTTTCAGGCTCAGGGCGCGTGCATGGCTCTGCTCTCCGTGCGTGTTTTCTTCAAGAAGTGTCCGGCGCTCACGCGCTCACTATCCGTCTTCCCGGAGACCGTTCCCCGCTCGCTGGTCCAGGAGGCAGTGGGCCAGTGTGTGGCCAACGCAGCACAGCCTGGCCCCAGTCCCAGACCGCCCAAGATGTTCTGCGGAGAAGATGGACAGTGGGTGGACCAGCCCACCACCACCTGCACTTGCCTGCCGGGCTTCGAGGCCAGCCATGGAGAGCTGGAGTGTAGAGcgTGTCCTGTGGGTCTGTTCAAGATGGGTTCTGGTACCGGTCCGTGTTCTGTGTGTCCTGAGAACAGTCAGACGGGAGAGACGGGTTCTGCTGCATGTGTGTGCCGCTCTGGGTTTTATCGCGCTCTGAGTGACAGTGCAGATACACCCTGCACACGTCCTCCGTCGTCTCCGCGCAGCCCCGTCCCGCAAGTAAACGACACATCTCTGACTCTGGAGTGGAGCGAGCCGTTGGACAGCGGCGGCCGCTCGGATCTCAGCTACAGCGTGGAGTGTAGGATGTGCTCCACCCCTGGAAGTCCCTGCACACTATGCAGTGACGGTGTGAATTATCGGCCGTCCCAAACAGGGATCCAAGGCCGGCGCGTGAGCATTTGGGGTCTGAGACCTCACACCACCTACAGCTTCACTGTCATGGCCCTCAACGGGGTCTCCGCTCAGAGTCAGCAGGGGCCTGCAGGAGAGACCATCAACATCACCACCAGTCCCAATGTTCCTGTGTTGGTTTCGGGCTTGAGGAAGAGCACAGCCACTGAATCCAGCCTGACGCTGTACTGGAACACACCCACCCAGTCACACTACAGGATCCTGCAGTACCAGATACGCTACTGCGAGAAGGAGCGCGGATCTGAAGAAAACTCCTGTCATTATATGGAGAGCAATAACAACGAGGTGGTTTTGAGCGACTTGCGAAGGGCCACGCAGTATGAGGTTCAAGTCCGAGCTCGGACATTCGCCGGATATGGAAGCTTTGGTAAAGCCATCCTCTTTCGAACTCTACCTGACGAAGATGATTCCTCGTCTCCCCTGCTTGTTACTGGGATCCTGATAGCCATGGGGATGCTGCTCCTCATCATCGTCATTGGGGCGGCCATTTATTGCATAAGGAAGCAAAATAACTACAAAGATCCAGAGCTGAGCGACAAAAACGGACAATATCTCATGGGTCAAGGAGTGAAGGTCTACATCGATCCCTTCACTTATGAAGACCCTAATGAGGCCGTGAGAGAGTTTGCTAAAGAGATCGATGTCTCGTGTGTCAAAATCGAGGAGGTTATTGGGGCAGGTGAGTTTGGGGAAGTGTGTCGGGGACGACTGAGGATTCCGGGTAAGAAGGAGAACTATGTGGCCATCAAGACCCTGAAGGGTGGATATACAGACAAGCAAAGGAGGGACTTCCTGGCTGAGGCCTCCATCATGGGCCAGTTCCAGCACCCCAACATTATTCACCTGGAGGGCATAATAACAGCAAGCTGCCCCGTCATGATCCTCACCGAATTCATGGAGAACGGAGCTCTGGACTCTTTCCTCAGACTCAACGATGGACAGTTTACACCGATACAGTTAGTCGGGATGCTGCGGGGCATTGCATCAGGAATGAAATATCTCTCAGAAATGAGTTACGTACACCGAGATCTTGCAGCGCGCAACATTCTTGTGAACAGTAACCTGGTCTGCAAGGTGTCCGACTTTGGTCTGTCGAGATTCCTGCAGGAGAATTCATCGGATCCCACGTACACCAGCTCACTGGGTGGTAAAATTCCCATCCGCTGGACGGCACCCGAAGCTATCGCCTTCCGTAAATTCACCTGCGCGTCCGATGTGTGGAGTTACGGGATTGTCATGTGGGAAGTGATGTCGTTTGGAGAACGACCGTACTGGGACATGAGCAACCAGGATGTGATTAATGCCATTGAGCAGGATTACCGTCTGCCACCGCCGCCGGACTGTCCCACATACTTGCaccagctgatgctggactgctGGCAGAAGGAGAGGACGGCCCGGCCACGCTTCGCCAACATCGTCTCAGCTCTGGACAAGCTGATCCGCAACCCGGCCTCACTCAAAATCACAGCGCAGGAGGGGGCGGGCCCCTCTCACCCTCTGCTGGACCAGCGGTCTCCACTCACGCCCTCATCCTGCGGGACAGTGGGTGACTGGCTGCGGGCCATCAAGATGGAGCGCTACGAGGAGACATTTCTGCAGGCGGGATACACGTCCATGCAGCTCGTCACCCACATCAACACGGAGGATCTGCTGCGTTTGGGAATAACTTTAGCAGGTCACCAGAAGAAGATTCTCTCCAGCATTGAGGCTCTCGGGATTCAAAACAAAGCACCAGGGAATGTGCTGTACTGa
>TCONS_00061302
AGAAGTCCTGATGAACACGAAAACGGAGACATCAGATCTGAAGTGGACGACACACTCTCGCTCTAAACCTGAGTGGGAGGAGGTCAGTGGTCTGGATGAGGAGAACAACAGTGTGCGGACCTATCAGATCTGCCAGGCGGACGGCTCCAGCAGTCATTGGCTGCGTAGTAAGCTGATCGAGCGGCGGGGGGCGTCACAGGTGTACGTGGAGCTGTTCTTCACTATGGTTGAGTGTTCATCTCGAAACACACACCACCGCTCCTGCAAAGAGACTTTCAACCTTTATTACTACCAAAGCGACACGGATGACGCCACAGCCACCCACCCGGCGTGGATGGAGAACCCCTACACCAAGGTGGACACAGTGGCCGCAGACTTCCTACTGCGCAAAGGCGGAGAGAAGAAAGTCAACGTGAAGACGCTGCGTTTGGGCCCGTTGAGCAAGCGTGGATTCTACCTGGCGTTTCAGGCTCAGGGCGCGTGCATGGCTCTGCTCTCCGTGCGTGTTTTCTTCAAGAAGTGTCCGGCGCTCACGCGCTCACTATCCGTCTTCCCGGAGACCGTTCCCCGCTCGCTGGTCCAGGAGGCAGTGGGCCAGTGTGTGGCCAACGCAGCACAGCCTGGCCCCAGTCCCAGACCGCCCAAGATGTTCTGCGGAGAAGATGGACAGTGGGTGGACCAGCCCACCACCACCTGCACTTGCCTGCCGGGCTTCGAGGCCAGCCATGGAGAGCTGGAGTGTAGAGGTGAGCGAGAGCAAACACAACAGACTGAAGAGCAAGCTAATTTAAGATTGGAAATATAAGCAAATAAAATCAAGCTGAGGTTTTCTGGATTCTGAGGAAAACTGCTAAATAAACCTTTGGCAATGCAGGTAACAAGTGTTGaggaagttacttttaaaaagtaatagattgCAAATGactgattactactggaaaattgtaatcggATTACTTTACTAGTCAttcaaaaagtaatcagattactaattgcTTGTTACTTTTAGTTTAACTCTGTTTTTTATTGAAATCTGTTCGTCAGAGAGCCACAGCATCAGATACACAGAATCATTAGACATCAACTGCTCCAGTGTGGTGGTAGAATACaattttgctcacgttttctttctctctgaataaaacaataattacatATTCATgcattaaggaaaaaaataataataataaaaaaaccaacaacagtagagagaataaataaatataaatactaaaaGGGTACTGAAgtagaaaattaaatattaatatatatttaaaaaataataataataaaataaaaaataaaaaa
>TCONS_00061303
ACATTAACTGCGATCGGCTGGAGTCACAACGCCTCGCTCCAACTTCCAGGATTTGCCGAGATTTTTTCCTTCTCATCGCAAAGCCGCTcggttttttttgtctgttttgacGAACACCTCCTGCATTCTCCATCGGATAAACAGCACGATGTTCGCTCGCTGACCTGTCGTGTATGTTTGCATCCGTGCATTGCTCTTATTTTGCTGgagatttgtgttttttaaagataCAAAGGACGCGGTGGATTGACGGAAATCAGAGGATTCGCTCGTCGGATGGAGGACGTCGATTAAACACCAGCAAGAACGCGGACATTTATCCTCGCACTCGTGGCCTGTCGGATATATGTTATTAGGTGGATCTTAATTCCATCCCATTTGAGAGTGGAAAATTAGGACAAGTCGACCTACACCCCTCACAAAGGGGTTCCGCGCAGCCGAGCGTATACGGCATGTTGTTGCTCCGTATGTTTTCGGCAAAACTGGCACATGCCTGCGTGCAGCTCTCCTTTATTTGAGAGATTTTTGGGGGGATTTGTGTTTCTGAAGTAGGCTAAAAATACAGTGTTTAGCCAACAACATAGAAAAGTTAGAAAACTCAACATTTCCTATATAGCTCTTTATTAGTTTATATGCTATAACTTTGTAACTTATTCTCCAAGTTGATCTTTCTATTTTTCTCTCATAACTTGGTGGCTGATCTAAATACTGCGACGAATTTCGCCGAGTGTTCATTCCTGATGGGTACAACAAGACCCAGCTGACGACTCTTGAACCTTTACACTGTTTACCCACCTTTGTAAACATTCACAAGTAAAACACTCGTGATTCCGCGATGGAGCTCTTCTCCAGGAATGTGGCCGCGTTTTGGATTATCCTGCTGGAGTTCCTGCTCGGATCAGTGGCGGAGGAAGAAGTCCTGATGAACACGAAAACGGAGACATCAGATCTGAAGTGGACGACACACTCTCGCTCTAAACCTGAGTGGGAGGAGGTCAGTGGTCTGGATGAGGAGAACAACAGTGTGCGGACCTATCAGATCTGCCAGGCGGACGGCTCCAGCAGTCATTGGCTGCGTAGTAAGCTGATCGAGCGGCGGGGGGCGTCACAGGTGTACGTGGAGCTGTTCTTCACTATGGTTGAGTGTTCATCTCGAAACACACACCACCGCTCCTGCAAAGAGACTTTCAACCTTTATTACTACCAAAGCGACACGGATGACGCCACAGCCACCCACCCGGCGTGGATGGAGAACCCCTACACCAAGGTGGACACAGTGGCCGCAGACTTCCTACTGCGCAAAGGCGGAGAGAAGAAAGTCAACGTGAAGACGCTGCGTTTGGGCCCGTTGAGCAAGCGTGGATTCTACCTGGCGTTTCAGGCTCAGGGCGCGTGCATGGCTCTGCTCTCCGTGCGTGTTTTCTTCAAGAAGTGTCCGGCGCTCACGCGCTCACTATCCGTCTTCCCGGAGACCGTTCCCCGCTCGCTGGTCCAGGAGGCAGTGGGCCAGTGTGTGGCCAACGCAGCACAGCCTGGCCCCAGTCCCAGACCGCCCAAGATGTTCTGCGGAGAAGATGGACAGTGGGTGGACCAGCCCACCACCACCTGCACTTGCCTGCCGGGCTTCGAGGCCAGCCATGGAGAGCTGGAGTGTAGAGGTGAGCGAGAGCAAACACAACAGACTGAAGAGCAAGCTAATTTAAGATTGGAAATATAAGCAAATAAAATCAAGCTGAGGTTTTCTGGATTCTGAGGAAAACTGCTAAATAAACCTTTGGCAATGCAGGTAACAAGTGTTGaggaagttacttttaaaaagtaatagattgCAAATGactgattactactggaaaattgtaatcggATTACTTTACTAGTCAttcaaaaagtaatcagattactaattgcTTGTTACTTTTAGTTTAACTCTGTTTTTTATTGAAATCTGTTCGTCAGAGAGCCACAGCATCAGATACACAGAATCATTAGACATCAACTGCTCCAGTGTGGTGGTAGAATACaattttgctcacgttttctttctctctgaataaaacaataattacatATTCATgcattaaggaaaaaaataataataataaaaaaaccaacaacagtagagagaataaataaatataaatactaaaaGGGTACTGAAgtagaaaattaaatattaatatatattt

Function

symbol description
ephb4a Predicted to enable ATP binding activity and ephrin receptor activity. Acts upstream of or within convergent extension; ephrin receptor signaling pathway; and vasculature development. Predicted to be located in plasma membrane. Predicted to be integral component of plasma membrane. Is expressed in several structures, including axis; cardiovascular system; digestive system; nervous system; and neural tube. Used to study lymphatic system disease. Human ortholog(s) of this gene implicated in hereditary lymphedema. Orthologous to human EPHB4 (EPH receptor B4).

GO:

id name namespace
GO:0048845 venous blood vessel morphogenesis biological_process
GO:0006468 protein phosphorylation biological_process
GO:0001568 blood vessel development biological_process
GO:0048013 ephrin receptor signaling pathway biological_process
GO:0060026 convergent extension biological_process
GO:0016310 phosphorylation biological_process
GO:0035475 angioblast cell migration involved in selective angioblast sprouting biological_process
GO:0007169 transmembrane receptor protein tyrosine kinase signaling pathway biological_process
GO:0005886 plasma membrane cellular_component
GO:0005887 integral component of plasma membrane cellular_component
GO:0016020 membrane cellular_component
GO:0016021 integral component of membrane cellular_component
GO:0016740 transferase activity molecular_function
GO:0005524 ATP binding molecular_function
GO:0000166 nucleotide binding molecular_function
GO:0004672 protein kinase activity molecular_function
GO:0016301 kinase activity molecular_function
GO:0005003 ephrin receptor activity molecular_function
GO:0004713 protein tyrosine kinase activity molecular_function
GO:0004714 transmembrane receptor protein tyrosine kinase activity molecular_function

KEGG: NA

ZFIN:

id description
ZDB-GENE-990415-62 Predicted to enable ATP binding activity and ephrin receptor activity. Acts upstream of or within convergent extension; ephrin receptor signaling pathway; and vasculature development. Predicted to be located in plasma membrane. Predicted to be integral component of plasma membrane. Is expressed in several structures, including axis; cardiovascular system; digestive system; nervous system; and neural tube. Used to study lymphatic system disease. Human ortholog(s) of this gene implicated in hereditary lymphedema. Orthologous to human EPHB4 (EPH receptor B4).

Ensembl:

ensembl_id ENSDARG00000100725

RNA

RNA id representative length rna type GC content exon number start site end site
TCONS_00061300 False 2940 mRNA 0.55 16 68408346 68456987
TCONS_00061301 False 3056 mRNA 0.55 17 68408404 68495224
TCONS_00061302 False 1308 mRNA 0.46 3 68449421 68456992
TCONS_00061303 True 2186 mRNA 0.46 4 68449455 68495967

Neighbor

gene id symbol gene type direction distance location
XLOC_031652 h1m coding downstream 75265 68326858 ~ 68333081 (-)
XLOC_031651 KIF1C coding downstream 148599 68228268 ~ 68259747 (-)
XLOC_031650 CABZ01083943.1 coding downstream 194012 68205952 ~ 68214334 (-)
XLOC_031649 slc25a11 coding downstream 315177 68076913 ~ 68093169 (-)
XLOC_031648 spag7 coding downstream 333754 68059924 ~ 68074592 (-)
XLOC_031654 dlg4a coding upstream 33761 68529728 ~ 68641353 (-)
XLOC_031655 LO017735.1 coding upstream 121991 68617958 ~ 68618089 (-)
XLOC_031656 NA coding upstream 126131 68622098 ~ 68668542 (-)
XLOC_031657 mepce coding upstream 269916 68765883 ~ 68782641 (-)
XLOC_031658 her1 coding upstream 292691 68788658 ~ 68795063 (-)
XLOC_031644 NA non-coding downstream 436004 67964507 ~ 67972342 (-)
XLOC_031627 BX897741.1 non-coding downstream 1243927 67161442 ~ 67164419 (-)
XLOC_031620 CU929288.1 non-coding downstream 1871012 66537217 ~ 66537334 (-)
XLOC_031616 NA non-coding downstream 2164214 66239915 ~ 66244132 (-)
XLOC_031659 NA non-coding upstream 317956 68813923 ~ 68816110 (-)
XLOC_031662 NA non-coding upstream 394510 68890477 ~ 68893011 (-)
XLOC_031664 dre-mir-2188 non-coding upstream 525892 69021859 ~ 69021962 (-)

Expression


Co-expression Network