XLOC_031834 (klf1)


Basic Information

Item Value
gene id XLOC_031834
gene name klf1
gene type coding
species zebrafish (Danio rerio)
category of species model fish

Chromosome Information

Item Value
chromosome id NC_007117.7
NCBI id CM002890.2
chromosome length 60270059
location 8129543 ~ 8140958 (+)
genome version GRCz11_2017_zebrafish_Genome

Sequence

>TCONS_00062356
GAAGATAAAGTAACCTTTAATGGCACTGTGaagttttatgtaaatatatttgactTTAACACTAAATTCTGGGTTCTTACCCTTTGTGTATTgcacatgtaaataaatacaattctggACAAATATCAAACACTCTATTTGGAGACAATTGTTTGTGTAATAAATGCTGAAAGGGCACCAAACGGATGGCTGTGACTCAAGCCGTACTGCCTTCATTTTCAAACTTCTGCACCAACTCCGAAAACATGAAGTTTGAAAAAGGCTTTCTGGATCTGGACTCCAAGGATCTGCACCAAAGCCCAGCCAGCTACAAACCTTCCCAGTTCCTGACTGATGAGCACCAGGACGACAGCGAGGGATGCTGGGACATGGAGTTCCTACTGTCTGACTGGGCCAGTATGTCACCTGAACGGTCCAACTCTCAAAACTACACTCCCCAGCGGCCGACCCTACAGGACCAGCTTCACAGTCCAGATCTTTATCAGGAGCTGAACGCACCAAAACCAAACAGACATCAAGTGTGCGTTGCAAGTTCCCTAGCTGAGCTGCTTCCTCCTGAAGCAACCTTAAGTTCCTCCCTGCCTCCTGACCTCCAGTTTAATTGTGGATTTCTAGATCAACAAGCTGCCAAATCATATTCCCAGGCAGAAAACCCCCAGCAGTTCAGTGCTTTCCCTGTCACAAGTAATGTAAACAGAGACAGCAGCATGGGAAAAATGGGGAAGTCCTGGGATTTCGGACATTACTATCAGCCTGCGCCTCTGATATCCTTCCCAGACTCCAAATTTGTCCAAACGCAGGGGATCACAATGGAAACAGTGGTCTTTCCTCCGCATCATCACTACAACTTCATCCCGAGCTACTCGCATCCCAGACTCTACCAGCAGCAGGCAAACTACGTCCACAGGCCGCCGCCGCAGAGCCACTTTCCCTCCACACAGAGCATGGTGCCCGACTCCACAGTGCCGCCTGCAGGCCTTGAGAGCAAGCGCATCCGCAGAGGGCTGGTCAAGAGGAAAGCCACGGTGCACAGCTGTGAATATCCAGGCTGCCAGAAGACATACACCAAGAGCTCTCATCTCAAAGCACACCTCCGTACACACACAGGTGAAAAGCCGTATCACTGCACATGGGATGGCTGCGGGTGGAAGTTCGCCCGTTCAGACGAGCTGACGAGACACTTCCGAAAACACACCGGACAGAAGCCGTATGAGTGTCTGCTGTGCCACAGAGCCTTCAGCAGGTCCGACCACCTGGCGTTACACATGAAGAGACACGTGTGAGGAAAAACactaacaaaacacaacaaaccaCATGAGCTTCATCCATTTCAAAGGCTTGCGAGGACCTGTGTTCAGCTGGAGAGATGCTGGACGCTGTTTATGCATGATAAAGAAAGTATAGAAGCACtattatatacacatacaatcagtgttgggggtaacgtgTTACAAGTAATGCAGATATTACTTTttgaagtaaagagtaaagtgatgcagtacttttaaaaatgaatgtaatgcaagttactttttagtttaattaaccCAGATAGCAcacatacacttgaagtcagaattattagtccccctgtatacttttctcccaatttctttttaacagagaaaaaatttatttctgaacacaatagctttaataactcatttctaataactgatttattttatttactttgccatggtgataataaataatattttactagctattttttcaagacacttctatacaacttaaagtgacatttaaaggcttaactaggtttattaggcaattcattgtataacagtggtttgttctgtagacaataaaaaaatgcttaaggaggctaataatattgaccttaaaatgtctttaaaaaattggaaactgcttttattttagcggaaataaaacaaataagactttctctagaagaaataaatattataagaaatactgtgaaaagttccttgctctgttaaacatcatttgggaaaaataaaaaaaaatgtaacaaataaataaaataaaataaattacaggagggcgaatacttttgacttcaactatacgtCGAGGAAAAGTCAATGAAAGATCGTAACATCTACAGCATCGCATTCGatcaaacatttgtattttaatgagCCGTCTTCTTTACCTCTATACACTGTCTATGAATCTTCAACTCCTGAAATTATGCGATGGCAAGCTCTGGTAAAAAGACGCAACAACTTCATCTTGAATAGCTTTAAAAAATTCATTGTTGaattaaaattgacattttgaAAAGTGGATTGTCTCACTGGACTGACTACTTAATGCATaggaaaaaagtacaaaagtagcaaacatgttgctttaaatttgcattattctgtatatacagcatgtatagctcaAAAGATCACTTTATTCTAAACAActtttagatgtgtgtgtgtgttttttaaagctAAACAAAAGTTATAGAGAGTGTTGTTAGTTGCAAAGCtcgtcatataaaaaaaaaaaaaaaaaaaaaa

Function

symbol description
klf1 Enables DNA-binding transcription factor activity and sequence-specific DNA binding activity. Acts upstream of or within positive regulation of gene expression and primitive erythrocyte differentiation. Predicted to be located in nucleus. Is expressed in blood; hematopoietic cell; intermediate cell mass of mesoderm; and posterior lateral plate mesoderm. Human ortholog(s) of this gene implicated in congenital dyserythropoietic anemia type IV. Orthologous to human KLF1 (Kruppel like factor 1).

GO:

id name namespace
GO:0010628 positive regulation of gene expression biological_process
GO:0006357 regulation of transcription by RNA polymerase II biological_process
GO:0060319 primitive erythrocyte differentiation biological_process
GO:0005634 nucleus cellular_component
GO:0043565 sequence-specific DNA binding molecular_function
GO:0046872 metal ion binding molecular_function
GO:0003676 nucleic acid binding molecular_function
GO:0003700 DNA-binding transcription factor activity molecular_function
GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding molecular_function
GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific molecular_function

KEGG:

id description
ko03000 Transcription factors

ZFIN:

id description
ZDB-GENE-980526-55 Enables DNA-binding transcription factor activity and sequence-specific DNA binding activity. Acts upstream of or within positive regulation of gene expression and primitive erythrocyte differentiation. Predicted to be located in nucleus. Is expressed in blood; hematopoietic cell; intermediate cell mass of mesoderm; and posterior lateral plate mesoderm. Human ortholog(s) of this gene implicated in congenital dyserythropoietic anemia type IV. Orthologous to human KLF1 (Kruppel like factor 1).

Ensembl:

ensembl_id ENSDARG00000017400

RNA

RNA id representative length rna type GC content exon number start site end site
TCONS_00062356 True 2525 mRNA 0.40 3 8129543 8140958

Neighbor

gene id symbol gene type direction distance location
XLOC_031833 si:ch211-207j7.2 coding upstream 35550 8079974 ~ 8093993 (+)
XLOC_031832 palm3 coding upstream 54694 7977611 ~ 8074849 (+)
XLOC_031831 myh10 coding upstream 471258 7553085 ~ 7658285 (+)
XLOC_031830 pa2g4a coding upstream 578403 7533601 ~ 7551140 (+)
XLOC_031829 erbb3a coding upstream 598116 7466223 ~ 7531427 (+)
XLOC_031835 nfil3-3 coding downstream 12855 8153813 ~ 8154866 (+)
XLOC_031836 nfil3-5 coding downstream 31269 8172227 ~ 8180042 (+)
XLOC_031837 NA coding downstream 123806 8264764 ~ 8271403 (+)
XLOC_031838 gcdha coding downstream 173493 8314451 ~ 8330577 (+)
XLOC_031839 NA coding downstream 198313 8339271 ~ 8346941 (+)
XLOC_031828 AL953886.1 non-coding upstream 675712 7453355 ~ 7453831 (+)
XLOC_031826 AL953886.2 non-coding upstream 693843 7429311 ~ 7435700 (+)
XLOC_031820 NA non-coding upstream 920914 7207593 ~ 7208629 (+)
XLOC_031817 AL929341.1 non-coding upstream 1249494 6879927 ~ 6880049 (+)
XLOC_031811 NA non-coding upstream 1388135 6718916 ~ 6741408 (+)
XLOC_031840 NA non-coding downstream 309353 8450311 ~ 8453642 (+)
XLOC_031844 CU571254.1 non-coding downstream 550450 8691408 ~ 8691993 (+)
XLOC_031845 CR954285.2 non-coding downstream 564191 8705149 ~ 8997996 (+)

Expression


Co-expression Network

Homologous

species gene id symbol gene type chromosome NCBI id location
grasscarp (Ctenopharyngodon idella) CI01000024_04565630_04567525 KLF2 coding CI01000024 null 4565222 ~ 4567634 (-)