XLOC_032237 (gata2b)


Basic Information

Item Value
gene id XLOC_032237
gene name gata2b
gene type coding
species zebrafish (Danio rerio)
category of species model fish

Chromosome Information

Item Value
chromosome id NC_007117.7
NCBI id CM002890.2
chromosome length 60270059
location 40794015 ~ 40803800 (+)
genome version GRCz11_2017_zebrafish_Genome

Sequence

>TCONS_00062964
ACAGATCTCTCGTGTGACCACCTGTGCCTGTCATCCTGATGCGGATCCCTGTACCTTTTGAACTGTAGGCGTGTGCCATGAAGTTGGAGTGACGAGATAGATAAGGAACATCGGCATCCCTGTCCTACTGAAAAGAGAGATGATGGATGCCCCAGCGGAACCCCGGTGGATGATGCATGCTCATCATTCAGCCATGATGGGCACCTCTGATTCGGTGTCTCCTCATGCAGGTCTGGGACATCATAGTTCGGGCTATATGGAGCCAGGTGCCCCATTATTACAACCAGACGAGGTGGATGTATTTCTCAGCCATTTGGACTCTCAGGGAAACCCCTACTATCATACACACGGGTCCCGTGCACGGATGTCTTACAGCCAGACGCATGCACGCCTTACGGGTGGCTCAATGTGTCGACCTCACCTTATCAACACTCACGGTCTTCCTTTACTGGACAACAGCAAATCGACCTTTTCTACAGCTCAGCACCACGGCTCATGGACCGTCAGCCACCTGGGCAAAGCGGTTCTGCATTCAGCAGGCGCCGAATCCTCCAACGGCCTGTACGCAGGCACCGGTGCGCCGGCCTCGGGTCCGATGCCGTGCCTGTCGATGACGCAACACTGCAGCGCACAGCTCTACTGCCTGCCGCCCACCCCGCCCAAAGATGTGTCCCCGGACCCGGCCTGTGCCGCGGTGAGGGATGCCGGGAAGTACCATCTCCATCTAGTCGACGGGATGAAGATGGAGTGCTCCAGTCCAATCCGTAGCAACCCGCATCTGGCGCAAACGACAACCCCTATACCTTCATATCCCGATTACTCAGTAGCCGGAGCGCACGAGTATCCCGCCAGTGTGTTCCACTCCAGAAATCTGCTCGGAAACATGACGACAAAATGCAAAAGTAAAAACCGCGCTTTCTCTGGACGTGAATGTGTAAATTGTGGAGCTACGTCGACTCCTCTGTGGCGGAGAGATGGCACAGGTCATTATCTGTGTAATGCATGTGGACTCTACCACAAGATGAATGGGCAGAACAGACCTCTCATCAGACCCAAGCGCAGACTGTCAGCATCTCGACGAGCAGGCACCTGTTGTGCCAACTGCCAGACTGGGACCACCACACTCTGGAGACGCAATGCCAACGGAGAACCCGTCTGCAATGCCTGCGGTCTATACTACAAACTACACAATGTGAATCGCCCACTTACTATGAAGAAGGATGGTATTCAGACACGCAACAGGAAGATGTCTGGCAAATCTAAGAAGAGGAGAGGAGAACACTTTCACCAGTTTGACAGTTGTGTGCACGACAAACCATCCTCCTTCAGCCACATGGCTAACATTCACCACCCATTCAATATGACTCCGCAAATACAATTACATCCTGCATTCAGTCACAGCAGCTTAGTCACTGCTATAGGCTGAGAGACACCTGTAGAAGACAACACTTACTGTCTCCATTCTTTGGTTTTACTGTACAGGACATTTCattaacatttcagatgtttattaTGCAAGGTTCAAAATTTGGTCTCGATTTTAAAAAGATGCACTTTATTTTGTGgatttatgaaatgtgttttaagCCAACATAGAATCCGATCGCAGTACACCAAGAGTTTTGCTAATTaggtaatttttaataaatatttattcaagtaTAGTCTCAACTTTCATGCGTGATTATGTCATTCATCCGACTGCACTGTTATGGAACTGTGAAGAAGGAAGAAGCCCCATATtttaactataatataattttcaaaacatttgtaattgtctttaatttatttttcagatCTCTTATTTTCAAGCTTTATGTCAACTAGTATCAACATCAATAGAAAGTTACACTATCCTTAGTTTCTGTATACACATGTAACACTCAgaagaaactttttttaattgtacatttattttgaaattttagtaaataaatgattGTAAAACTGTC

Function

symbol description
gata2b Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Acts upstream of or within definitive hemopoiesis and hematopoietic stem cell differentiation. Predicted to be located in nucleus. Is expressed in several structures, including caudal fin; dorsal aorta; hematopoietic system; neurons; and vascular cord. Human ortholog(s) of this gene implicated in acute myeloid leukemia; immunodeficiency 21; mental depression; myelodysplastic syndrome; and myeloid leukemia. Orthologous to human GATA2 (GATA binding protein 2).

GO:

id name namespace
GO:0030097 hemopoiesis biological_process
GO:0006355 regulation of transcription, DNA-templated biological_process
GO:0045165 cell fate commitment biological_process
GO:0060216 definitive hemopoiesis biological_process
GO:0060218 hematopoietic stem cell differentiation biological_process
GO:0045944 positive regulation of transcription by RNA polymerase II biological_process
GO:0005634 nucleus cellular_component
GO:0043565 sequence-specific DNA binding molecular_function
GO:0046872 metal ion binding molecular_function
GO:0003700 DNA-binding transcription factor activity molecular_function
GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding molecular_function
GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific molecular_function
GO:0008270 zinc ion binding molecular_function

KEGG: NA

ZFIN:

id description
ZDB-GENE-040718-440 Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Acts upstream of or within definitive hemopoiesis and hematopoietic stem cell differentiation. Predicted to be located in nucleus. Is expressed in several structures, including caudal fin; dorsal aorta; hematopoietic system; neurons; and vascular cord. Human ortholog(s) of this gene implicated in acute myeloid leukemia; immunodeficiency 21; mental depression; myelodysplastic syndrome; and myeloid leukemia. Orthologous to human GATA2 (GATA binding protein 2).

Ensembl:

ensembl_id ENSDARG00000009094

RNA

RNA id representative length rna type GC content exon number start site end site
TCONS_00062964 True 1955 mRNA 0.47 6 40794015 40803800

Neighbor

gene id symbol gene type direction distance location
XLOC_032236 si:ch211-157b11.8 coding upstream 10374 40775800 ~ 40783641 (+)
XLOC_032235 slc26a6l coding upstream 61323 40723554 ~ 40732692 (+)
XLOC_032234 ccdc36 coding upstream 76967 40714811 ~ 40717048 (+)
XLOC_032233 rereb coding upstream 104973 40671336 ~ 40689042 (+)
XLOC_032232 eno1b coding upstream 124609 40661703 ~ 40669406 (+)
XLOC_032238 ruvbl1 coding downstream 28835 40832635 ~ 40841032 (+)
XLOC_032239 zgc:112163 coding downstream 70406 40874206 ~ 40875253 (+)
XLOC_032240 eif4enif1 coding downstream 118772 40922572 ~ 40947671 (+)
XLOC_032241 patz1 coding downstream 147427 40951227 ~ 40968320 (+)
XLOC_032242 NA coding downstream 180797 40984597 ~ 40986135 (+)
XLOC_032231 NA non-coding upstream 137969 40652905 ~ 40656046 (+)
XLOC_032225 NA non-coding upstream 242023 40545858 ~ 40551992 (+)
XLOC_032222 CU463231.2 non-coding upstream 312238 40475711 ~ 40481777 (+)
XLOC_032220 BX936393.2 non-coding upstream 342175 40448634 ~ 40451840 (+)
XLOC_032217 CU467879.1 non-coding upstream 744570 40043615 ~ 40049445 (+)
XLOC_032245 NA non-coding downstream 276710 41080510 ~ 41082985 (+)
XLOC_032251 AL732567.2 non-coding downstream 390887 41194687 ~ 41194801 (+)
XLOC_032256 dre-let-7j non-coding downstream 650991 41454791 ~ 41454873 (+)
XLOC_032260 NA non-coding downstream 961838 41765638 ~ 41773554 (+)

Expression


Co-expression Network

Homologous

species gene id symbol gene type chromosome NCBI id location
grasscarp (Ctenopharyngodon idella) CI01000340_09867373_09873132 GATA2B coding CI01000340 null 9865705 ~ 9873388 (+)