XLOC_032928 (lepr)


Basic Information

Item Value
gene id XLOC_032928
gene name lepr
gene type coding
species zebrafish (Danio rerio)
category of species model fish

Chromosome Information

Item Value
chromosome id NC_007117.7
NCBI id CM002890.2
chromosome length 60270059
location 31184058 ~ 31233696 (-)
genome version GRCz11_2017_zebrafish_Genome

Sequence

>TCONS_00063966
AAGCAACGGTGGCGGAGCTCGAGTTCAGGATGCCGAGCTCTGAAAACACTCACGAAGTCACGCGCCTCTTCTAGTCTGCACAACAGGACAGACATTCCTCATAACAGCGGGAAAAGTCTAACTCTGTATCTGCTGCTTTTACCTTATTTTTGAGCGGAGTAGGACACGTAAGAGTACTAACGTCAGTCAGAGGCGCGAACTGCTCAGACTCCCCATCAAGAAGAGAAATGATGCTGACGAGCAAGTGAAATGATGTCTGTCTTCATCATGCTTGCACTGCTTGTGATTTTTATTGCCGTTTCACAAGGCCTTGCAGATTTGAATCCTTCTGATGGAGTCAGCGATGGTGTTTACGAAGACCTGAAGTGGAAAGCTCTCCTGTGTTGTGATCATCCTGTTCAGACGCTTAACAGTGGTCTTTCAGAACACCCACCCGAACAACACTGCCAACTGCTAAATGCTACAAAACAACAGTCTTTTGgaagctgtttggacatccTGTGCTGGCTTGAAGGTGAACGGGAAAATTTGATTTGTAATGCAAAGACCCGTAGAGCAGCAGCAGCTTCCACTCTGGTCAGCGTCAGCCCTCATCAATTAGTtgTACAGATGGATGTACATTCAGATGAAGCAAATTCCACTGCTCAGTGTGTTGGAGAAGAGACTGCCATCTGCTCCGTTTCTCTTCACGGCGGGGATGCAACAGTCTCATTAGTTATAATTATATCTGAGAATGGGACCACTGCACAATCACAGAAGATGCAAGTCAGCACATATGAACTACAAAGACCTGGCGCACCTGTCAATCTGCATTACAATGTGACGACAGAAGGGGAAGTTATATTCAGGTGGACCGGCACACAACCTGACAACAACACTATAAACTATGAGATCCAATACTCATCCAATTCCTTGCTTCAGCAGTGGAAGGTATTGAAGGTCAAAGGTCGTTCATGGGTTGCTCTGAATGAGCTCAGTTCTGACATCAGATACACGGTTCAAGTGCGCTGCCAAAACCATCTCGGCTACTGGAGTGAATGGAGCCAACCTTTCTATTTCAAACTAGATGTCAGTTACATCCCTGCTGAAGTCTTCACAACGCAGGAGTCAGAGGTGACAGTTTACTCTGTGTTCCACAACCGCAGCTGGAGCGCCAGTAAAGCCGTGTGGTTTCTGAACGGCAAGATGAAGATACCAGAAAGCCAGTACAGAGTCATCAATGAGCAGGTCAGCACAGTCACTCTAAAGATGGACAAAGCAGGATTTGACACTCTGATGTGCTGCCTCACATTGGGAGAGAAATCTATGTGCTCCATCGCCTATGCCAAAATATACACAGAAGGAAGGTTTAACGCAAATATTACCTGCGAAAGCGAGTATTCATATGTGGACACCATGATCTGTAAGTGGAATCAGAGCAATTGGGCACAGGCCAGACTCCTTTACAGACAATACAGATCAAAGTGCACTGAAGAAGCTGAAGAAGACACGTCTTTGGTGAAAGAGTGTCCATCTAAAGCAGGAGATCACAGACAGTGCACCTTAAGCCAAATCAGCATGATCTTTTGCTATAAATTCTGGCTTGAAGTGGAAGGAGGACGTGGCCAATCGTTTCCTGTCTACGTTACGCCTATTGACTATGTGAAACCGTCACCTCCCTTTGATCTGGAGGCAATCACTCTGCCGAGTAAAACCCTGAGTGTAAGGTGGAAACGCCCCTCTTTGCCTGTATACGGCATGCAGTACGAGCTGCAATTCAAGGCTTTGGCTGGAATGGCAAATACGCAATGGAAGGTCATTGGTCCTCTATTGGAACCACAGGCAGAGATTCAGCTTGAGGAGTCCTGTGTTCACTTTAAAGTAGAAGTTCGCTGTAAAGACGTGAACGACACTGGATACTGGAGCGACTGGAGCAATAGTCACATTTCCACTGTTTTCAACTTGAAagCACCAGAGATGGGACCAGACTTCTGGCGCATTTTACAAGAGGATCCTACTAGGAATGTGACAAACGTTACACTGATCTTTAAGcaGCCCATTCTAGCAGGAGATCCAAATAGCTGCGTGGAGGGTTTAGTGATTAAACACCAGGCCTCAGGTGGAGTCATGTGGTCAAATGAAACAACCTTGGCTCGGTTTCACTCATTCCAGTGGAGGAAGGAAGCGCATACAGTCACTGTGATGTCTCGCAACGCTTTGGGCATTTCCACATGGAACAGAAACATCACGCTCTTACGTCAAGCCAAACggcGATGTGTGCGTTCGTTCAGTGCAGTTGCAAATGTGAGCTGTGTGCACCTCTCCTGGAGCCTGTTATCTGATCAGCCGGTGCCTCAGTCATTTGTTATTGAATGGTTAGACCTGAACAAAGACCCCGAAAAGGATGTGTCTCTCACAGAAAGAATACAGTGGGTCAGGGTTGAGTCCAGATCGAGAGATCTTTCTCTTTGCCGTCGTTTTTATGGCTCAGAGGAGTTCACCTTGTATCCAGTGTTTGCGGATGGTGAAGGGGAACCGGCTCGATACACAGCTACAAGGGGTGATCCTGCAGCGTATATACTGCTACTGATCATCGCCTTCCTGTCAGTGGTGCTGTTTGTCACACTGATGATGTCACAGAACCAGATGAAAAAACTCATGTGGAAGGATGTTCCAAATCCCAACAAGTGCTCTTGGGCCAAAGGAATGGACTTCAGGCAGATTGACACCATGGAGAGCCTGTTCCCTCATTCAGAGGGTCTCACTGCCTGTCCATTGCTGCTTGTCTCCGAGAGCATCTGTGAGGTTGAAATCATCGAGAAACCTCATCCTCTTACCATTGAAAACGTAAAAGACAATGAAGAACTTCCCTCCGGGGACAAGACAACCACAGACTCTGGCCTTCAGGGAGACTCTTCTGAAGCTCTGGAAGCATCTACTGCTGCTCCCACTCCAGAAACATCAGGCCAGTCTTCAGTCACGTACTCCACCATCCTCCTCTCCGACCAGCCCAGCCAACTCCAAAAGCAGCAGGAGAGTCTCAGCAGCTCCAGTGACGAAGGCAACTTCTCTGCCAACAACTCGGACATTTCCGGCTCCTTCCCTGGAGGACTTTGGGACTTGGAGAACAGCAATCCTCGCCATTCCAGCTCCTACAACTCTGTGGAGGAGTTTTCGGAAACATCAGAACCTGATTATGAAGCTTCGGAAAACACAGGTTTAGCTAAAGACCTCTATTACCTCGAGATGACCGGAGaggagaaagaagaagaagaagaagaagaagaagaagaagaagaagaagacgaacCAGAGGAGGGTCAAAGTAAGAATAAAAGAGTGATGGGTGTAAACCCCAGGCCTCTACTGGAAAGCCAAAATTCCACAGCCAGCAATTCCAATAACATGTCTCACAGCATTCCTCTTTATCTGCCTCAGTTTCGAAGTGAATGTATCAATCCAACGTGAAATATTGAGTGGAGAGCAGCACCATCTTGTGGTAACTTGAGATAATATTGTTCTTCACTGGATGGAGGTTCATATAATGCCTGCATCAAATTGCTTTTCCCCCCCAAATGAGATTGTTTTTCTTTAAGCTTCAGGTAGcactatttaaagaaataaatcttGTTAAATTGTGATTCAAAaagcaattaattatttttaagctCCAGGATTTCTGTGCTTTGTAAGGCTGCACAGTTTGGCTTAAAATGTTATCATTTATCactatacataaaataataactattattactGCTTAatcaatattaaacaaaaaaataaatgtttcaatggTATTTTAACAAtgccataaaataaaaaacattctaTTTGAGACAATAATAGTACATTTTACTTataatagtactaataataatTCCAACACATTTTGGGGGgattctcctcatccaccaccagtacAACAGTAAcaataaagcacttttttttttcttttttttattctcaatCCATCAGCTGcaggatatttttgtttagttGACAACAGCCTGCTTCTCATTACATGTTTGAGAAAATGTTGGCACATGGTGCATTGTTTTTTTCACAGTGCAGGTTAAAAGTGAACCAAACTTACTGTAGATCAGCTGCAGAGATCAGTTTCTGCATCAGTTTTTCCCATGTGAAAAGTTCACTCTAAAGTTCATTCTGAAGCACCAGCACATATCATTTTGATGACAATTGCACTAAACTATTTAGCGACATCAGCTTTGTTTTTGATTACCTGAGCAGTCATAACCGTAATTTACTCAATCTGCTCCAAAATCGACTTACAATTctttcaggagttcacacttagctgatgattgattataatgcTTGTTTGGTATGCCgtccctggagagagccctgagctcataagatcctcgagcctggggctccctcccatttgcaaggcgagaggggagtttgagctcaggtcgatcaagaactcccctgctgaaGTAGCTAATGAACacatagtgattgctcttaagagataactatttaataggagcatgtctatagtgccaatttggattagtcaattaacttaaattgaatgtttttggatggtgggaggaaaacAGGGAACCCATATAaggatggggagaacatgcaaacttcgtagagaaacgtcagctggcttggtaaggactagaaccagtgacgttcttcttgcgaggaaacagtgctaaccactgtgcacCATGCAACTCATCTAGGAAGGGAAACGGAGTAGGCTGAAGATAATGAAcagaagatggctgttatatggaacttagggtatttatagtggcttaggagtcgtctgattggtgagtcataaattggataatgcgggaccagctggaAGCAATCATtaacatgtgatcctctcgaaataagtttataaataaactttactgagtaaaacaactaaaatgttcCTTTTACGATTTGACTCCAGAAAACTCTTTATTTGCTTGAATCATCCCTGATACAGTATATAACTTTGAAGGTTTACAGCCAGATCTCCTGGCCTCAGCTTATGAGTATCCAAGCACAGTTTAAGCTCCAAATGTCTCATTGATAGGTTGATGATCAGCCTGTCATATCTGAAACTCGCTGCTTTCCACCTTCATCACATGGAGCCTTTCATAAGTGAAGTAAAATCACACAAAGACCTCATGAACTAGAAGGAAGTGCTTTAGCAGGAAGACTGAAGAAGGAAGGACCTTGTTTTAGCTCTCTCAGTATGGTGGTTTCTGTAGCAGTCATGGTTTTGTGGCTGTTTATGGAATTTTGGTGCTTCGTCAAGTCCAGGTTATCATAAGCAAATGGACATTTTAAAGAGGCGTCCATCTAAATATCAGCTTTGTGAATAAAAACCTTTCGTGTCTTCATTCACATCAGGCTTATTCGCTTCATATGAATGTATATTTTGTCAGTGAGGTCGGTGTTCTCTGAAAACTCAAATATTTTGAGTCTAAAAAAATGTCCTCTATTTTCAGTGTATGGTATTTTTGGATGAAATGGGGGTTGAGGGTAACCCGGTGAATAAAACTGATTATATATGTCAAGAGTATATGTAAGAATGTGTGTACAGTACTATTCACGTATTTCTTGTCTATTTTTCTGGTCAGAATAAACTATTTATTGCAATTACGgtcatttgttatttgtttacttgttcCCTATGCTGGGTAGTCCAAATAAAATTGCAATTGCATTTATGTCATTGCATTTCAAAATGTTATCAGTTTACAGTAACTTTCTAATGATGCATGGTTATAGGGTATATTGTTCACaaca
>TCONS_00063967
ATGTTTTTTTCAGATGTCCTCTCTTGTCCTCCTAGGTCTGTCTTCATCATGCTTGCACTGCTTGTGATTTTTATTGCCGTTTCACAAGGCCTTGCAGATTTGAATCCTTCTGATGGAGTCAGCGATGGTGTTTACGAAGACCTGAAGTGGAAAGCTCTCCTGTGTTGTGATCATCCTGTTCAGACGCTTAACAGTGGTCTTTCAGAACACCCACCCGAACAACACTGCCAACTGCTAAATGCTACAAAACAACAGTCTTTTGgaagctgtttggacatccTGTGCTGGCTTGAAGGTGAACGGGAAAATTTGATTTGTAATGCAAAGACCCGTAGAGCAGCAGCAGCTTCCACTCTGGTCAGCGTCAGCCCTCATCAATTAGTtgTACAGATGGATGTACATTCAGATGAAGCAAATTCCACTGCTCAGTGTGTTGGAGAAGAGACTGCCATCTGCTCCGTTTCTCTTCACGGCGGGGATGCAACAGTCTCATTAGTTATAATTATATCTGAGAATGGGACCACTGCACAATCACAGAAGATGCAAGTCAGCACATATGAACTACaagcaggagacccgtcgagagaacttaaaccctctcctctttcaatgaagtcgccagtgtttaagcattttggatttccagtaagttatgttgacaacgttcgtgttgtcgacaaaaaaaacacagttttgcaagctctgctatGTATTGAAGGTCAAAGGTCGTTCATGGGTTGCTCTGAATGAGCTCAGTTCTGACATCAGATACACGGTTCAAGTGCGCTGCCAAAACCATCTCGGCTACTGGAGTGAATGGAGCCAACCTTTCTATTTCAAACTAGATGTCAGTTACATCCCTGCTGAAGTCTTCACAACGCAGGAGTCAGAGGTGACAGTTTACTCTGTGTTCCACAACCGCAGCTGGAGCGCCAGTAAAGCCGTGTGGTTTCTGAACGGCAAGATGAAGATACCAGAAAGCCAGTACAGAGTCATCAATGAGCAGGTCAGCACAGTCACTCTAAAGATGGACAAAGCAGGATTTGACACTCTGATGTGCTGCCTCACATTGGGAGAGAAATCTATGTGCTCCATCGCCTATGCCAAAATATACACAGAAGGAAGGTTTAACGCAAATATTACCTGCGAAAGCGAGTATTCATATGTGGACACCATGATCTATGCATATGGGTGTCGTAGACAATACAGATCAAAGTGCACTGAAGAAGCTGAAGAAGACACGTCTTTGGTGAAAGAGTGTCCATCTAAAGCAGGAGATCACAGACAGTGCACCTTAAGCCAAATCAGCATGATCTTTTGCTATAAATTCTGGCTTGAAGTGGAAGGAGGACGTGGCCAATCGTTTCCTGTCTACGTTACGCCTATTGACTATGTGAAACCGTCACCTCCCTTTGATCTGGAGGCAATCACTCTGCCGAGTAAAACCCTGAGTGTAAGGTGGAAACGCCCCTCTTTGCCTGTATACGGCATGCAGTACGAGCTGCAATTCAAGGCTTTGGCTGGAATGGCAAATACGCAATGGAAGGTCATTGGTCCTCTATTGGAACCACAGGCAGAGATTCAGCTTGAGGAGTCCTGTGTTCACTTTAAAGTAGAAGTTCGCTGTAAAGACGTGAACGACACTGGATACTGGAGCGACTGGAGCAATAGTCACATTTCCACTGTTTTCAACTTGAAagCACCAGAGATGGGACCAGACTTCTGGCGCATTTTACAAGAGGATCCTACTAGGAATGTGACAAACGTTACACTGATCTTTAAGcaGCCCATTCTAGCAGGAGATCCAAATAGCTGCGTGGAGGGTTTAGTGATTAAACACCAGGCCTCAGGTGGAGTCATGTGGTCAAATGAAACAACCTTGGCTCGGTTTCACTCATTCCAGTGGAGGAAGGAAGCGCATACAGTCACTGTGATGTCTCGCAACGCTTTGGGCATTTCCACATGGAACAGAAACATCACGCTCTTACGTCAAGCCAAACggcGATGTGTGCGTTCGTTCAGTGCAGTTGCAAATGTGAGCTGTGTGCACCTCTCCTGGAGCCTGTTATCTGATCAGCCGGTGCCTCAGTCATTTGTTATTGAATGGTTAGACCTGAACAAAGACCCCGAAAAGGATGTGTCTCTCACAGAAAGAATACAGTGGGTCAGGGTTGAGTCCAGATCGAGAGATCTTTCTCTTTGCCCACGTGCTAAGCATCCTGAAAGAAAAGAAAGTCCTCTCGTCTTTGacaatataatttgtttttatgcaGGTCGTTTTTATGGCTCAGAGGAGTTCACCTTGTATCCAGTGTTTGCGGATGGTGAAGGGGAACCGGCTCGATACACAGCTACAAGGGGTGATCCTGCAGCGTATATACTGCTACTGATCATCGCCTTCCTGTCAGTGGTGCTGTTTGTCACACTGATGATGTCACAGAACCAGATGAAAAAACTCATGTGGAAGGATGTTCCAAATCCCAACAAGTGCTCTTGGGCCAAAGGAATGGACTTCAGGCAGATTGACACCATGGAGAGCCTGTTCCCTCATTCAGAGGGTCTCACTGCCTGTCCATTGCTGCTTGTCTCCGAGAGCATCTGTGAGGTTGAAATCATCGAGAAACCTCATCCTCTTACCATTGAAAACGTAAAAGACAATGAAGAACTTCCCTCCGGGGACAAGACAACCACAGACTCTGGCCTTCAGGGAGACTCTTCTGAAGCTCTGGAAGCATCTACTGCTGCTCCCACTCCAGAAACATCAGGCCAGTCTTCAGTCACGTACTCCACCATCCTCCTCTCCGACCAGCCCAGCCAACTCCAAAAGCAGCAGGAGAGTCTCAGCAGCTCCAGTGACGAAGGCAACTTCTCTGCCAACAACTCGGACATTTCCGGCTCCTTCCCTGGAGGACTTTGGGACTTGGAGAACAGCAATCCTCGCCATTCCAGCTCCTACAACTCTGTGGAGGAGTTTTCGGAAACATCAGAACCTGATTATGAAGCTTCGGAAAACACAGGTTTAGCTAAAGACCTCTATTACCTCGAGATGACCGGAGaggagaaagaagaagaagaagaagaagaagaagaagaagaagaagaagacgaacCAGAGGAGGGTCAAAGTAAGAATAAAAGAGTGATGGGTGTAAACCCCAGGCCTCTACTGGAAAGCCAAAATTCCACAGCCAGCAATTCCAATAACATGTCTCACAGCATTCCTCTTTATCTGCCTCAGTTTCGAAGTGAATGTATCAATCCAACGTGA

Function

symbol description
lepr Predicted to enable cytokine binding activity and cytokine receptor activity. Acts upstream of or within several processes, including response to glucose; sensory organ development; and type B pancreatic cell development. Predicted to be located in membrane. Predicted to be integral component of membrane. Predicted to be part of receptor complex. Predicted to be active in external side of plasma membrane. Is expressed in several structures, including digestive system; musculature system; nervous system; notochord; and pleuroperitoneal region. Human ortholog(s) of this gene implicated in several diseases, including artery disease (multiple); non-alcoholic fatty liver disease (multiple); obesity; obstructive sleep apnea; and type 2 diabetes mellitus. Orthologous to human LEPR (leptin receptor).

GO:

id name namespace
GO:0019221 cytokine-mediated signaling pathway biological_process
GO:0043010 camera-type eye development biological_process
GO:0048839 inner ear development biological_process
GO:0007399 nervous system development biological_process
GO:0009749 response to glucose biological_process
GO:0003323 type B pancreatic cell development biological_process
GO:0009897 external side of plasma membrane cellular_component
GO:0016020 membrane cellular_component
GO:0016021 integral component of membrane cellular_component
GO:0043235 receptor complex cellular_component
GO:0038021 leptin receptor activity molecular_function
GO:0004896 cytokine receptor activity molecular_function
GO:0019955 cytokine binding molecular_function

KEGG:

id description
ko04630 JAK-STAT signaling pathway
ko04152 AMPK signaling pathway
ko04080 Neuroactive ligand-receptor interaction
ko04060 Cytokine-cytokine receptor interaction
ko04920 Adipocytokine signaling pathway
ko04932 Non-alcoholic fatty liver disease
ko04050 Cytokine receptors
ko04090 CD molecules

ZFIN:

id description
ZDB-GENE-080104-1 Predicted to enable cytokine binding activity and cytokine receptor activity. Acts upstream of or within several processes, including response to glucose; sensory organ development; and type B pancreatic cell development. Predicted to be located in membrane. Predicted to be integral component of membrane. Predicted to be part of receptor complex. Predicted to be active in external side of plasma membrane. Is expressed in several structures, including digestive system; musculature system; nervous system; notochord; and pleuroperitoneal region. Human ortholog(s) of this gene implicated in several diseases, including artery disease (multiple); non-alcoholic fatty liver disease (multiple); obesity; obstructive sleep apnea; and type 2 diabetes mellitus. Orthologous to human LEPR (leptin receptor).

Ensembl:

ensembl_id ENSDARG00000070961

RNA

RNA id representative length rna type GC content exon number start site end site
TCONS_00063966 False 5772 mRNA 0.43 20 31184058 31233696
TCONS_00063967 True 3268 mRNA 0.47 18 31186383 31224563

Neighbor

gene id symbol gene type direction distance location
XLOC_032927 CR847887.1 coding downstream 36803 31069530 ~ 31147255 (-)
XLOC_032926 pde4ba coding downstream 229790 30851545 ~ 30954268 (-)
XLOC_032925 sgip1a coding downstream 344295 30709926 ~ 30839763 (-)
XLOC_032924 pars2 coding downstream 494932 30684696 ~ 30689126 (-)
XLOC_032923 ttc4 coding downstream 500421 30676995 ~ 30683637 (-)
XLOC_032929 dnajc6 coding upstream 45846 31279542 ~ 31348999 (-)
XLOC_032930 ak4 coding upstream 116405 31350101 ~ 31364551 (-)
XLOC_032931 raver2 coding upstream 197095 31430791 ~ 31576397 (-)
XLOC_032932 cachd1 coding upstream 357055 31590751 ~ 31739709 (-)
XLOC_032933 NA coding upstream 511595 31745291 ~ 31749784 (-)
XLOC_032920 NA non-coding downstream 725043 30452287 ~ 30459015 (-)
XLOC_032919 FP236850.1 non-coding downstream 962088 30221834 ~ 30221970 (-)
XLOC_032918 FP236850.2 non-coding downstream 981021 30202921 ~ 30203037 (-)
XLOC_032916 NA non-coding downstream 1098456 30083946 ~ 30085602 (-)
XLOC_032940 NA non-coding upstream 962112 32195808 ~ 32196825 (-)
XLOC_032944 NA non-coding upstream 1181380 32415076 ~ 32416753 (-)
XLOC_032945 LO017955.2 non-coding upstream 1340300 32573996 ~ 32592792 (-)
XLOC_032946 NA non-coding upstream 1453306 32687002 ~ 32687386 (-)

Expression


Co-expression Network