XLOC_032934 (ror1)



Basic Information


Item Value
gene id XLOC_032934
gene name ror1
gene type coding
species zebrafish (Danio rerio)
category of species model fish

Chromosome Information


Item Value
chromosome id NC_007117.7
NCBI id CM002890.2
chromosome length 60270059
location 31772182 ~ 31987940 (-)
genome version GRCz11_2017_zebrafish_Genome

Sequence


>TCONS_00063984
GAGCGAGAGAAAGAGCAAGCAGAGCAGAGGATCATCCGCAAACAGCAGCACATCTCTGCGGACAACCGTGGTTCAGTAAAGTCCTGAAGAGTCTCCGTTCTCCAGTAGTAACCCTGACCTGAGAGAAGAACGAGATTGCGGTGGATGTACGAGCGCTTAAGGGCAGAAGAAATGAGCAGAGGAACAGTGAAAGAGCCGCACGGATGCCAGCGCAACTTCACCCTGATCTGCGTGCTGCTCGCGCTCAGCTGCGGCGCAGAGATTCCCTCCGATCCGAGCGTTGTGTCCTCCTCCAGTTGGAACATGTCCAGGGCAGCTGAAAGAGATCACTTCCTAAGGCTGGACGCTCCTATGAATAACATTACTACTTCCCTCGGACAGACAGCTGAGTTGCATTGCCACGTTTCGGGGACTCCATCACCCTCAGTCCGCTGGCTTAAAAACGATGCCCCTGTGGTTCAGGAGCCACGGCGGGTCTCGTACAGACCGACTCCGTACGGCTCGCGCTTGAGAATCAAAAATCTGGACACCACAGACACCGGCTACTTTCAGTGTGTGGCGACCAACAGCTATGGCACAGTGTCAACCACAGGAATCCTGTTTGTCAAGTTTGATCCGGCTCCCACACCTCTGCCTGGACGACCTTCACCaGAGGATTTTGACGAGGAGGGTTTCTGCCAGCCATACAGAGGGATTGCGTGCGCTCGCTTCATAGGAAACAGGAGCATTTTTGTGGACTCGCTGCAGATGCAAGGCGAGATTGAGACCCAAATCACAGcggcATTCACCATGATTGGCACCTCCAATCACCTGTCCGATCGCTGTTCCCAGTTTGCCATCCCATCCCTGTGTCACTTTGCCTTCCCGACATGCGACCGCAGCTCTGGCATGGACAAGCCGCGGGACTTATGTAAAGATGAGTGTGAGATTCTGGAGAATGACCTATGTAAAACTGAGTACATCATCGCTCGATCAAACCCTCTCATTCTTAAACGACTCAAACTGCCTAAATGTGAAGATCTGGCCACTTTGGACAGTCCCGAGGCTGCAAACTGCATGAGGATTGGCATTCCTATAGCGGAGACCATTAATAAAAGTCACAAATGTTACAACAACAGTGGTTCAGACTACCGTGGCACTGTCAGTGTGACTAAATCTGGTCGTCAGTGTCAGCCGTGGAACTCTCAGTATCCCCACAGTCACACCTTCCTGGCCATGCGTTATCCAGAACTCAACGGGGGACATTCCTACTGCCGCAACCCCGGAAACAAGCACGACGCTCCCTGGTGTTTCACCCTCGATGAGGCTGTGCGCATGGAGCTCTGTGACATTCCTCCATGCGATTTGCCCAAGCATGGCAGCAGCAGCAACAGTATGGGAATCCTGTACATCCTGGTACCAAGTGTGGCTATACCACTGGCTATTGCTCTGCTGTTCTTTTTCATCTGTGTTTGTCGAAACAACCAGAAAGCCTCACGTCCACCAGCACCACGTCAGCCCAAACCCGTTCGTGGCCAGAACGTGGAGATGTCCATGCTCACAGCCTACAAACCAAAGAGTAAAGCCAAGGAGCTTCCTCTGTCTGCGGTACGCTTCATGGAGGAGCTGGGCGAGAGTGCCTTCGGTAAGATCTACAAAGGCCACCTGTACCTGCCTGGCATGGAGCACGCTCAACTTGTGGCCATAAAAACCCTGAAGGACATCTCCAGTGCACAACACTGGGGCGATTTCCAGCAGGAAGCATCCGTCTTGGCAGAACTTCACCACCCTAATGTGGTTTGTCTCCTGGGTGTAGTGACCCAAGAGCAGCCCGTCTGCATGCTCTTCGAGTTCCTGGCCCAAGGCGACCTCCACGAGTTCCTCATCATGCGCTCTCCACATTCAGATGTGGGCTGCAGCAGCGACGAAGACGGCACTGTCAAGTCCAGCCTCGACCACGGAGACTTCCTTCACCTGGCCATTCAGGTGGCGGCTGGAATGGAATACCTGGCCAGCCATTTTTTCATCCACAAAGATCTTGCAGCCCGTAACATCCTAGTTGGCGAACAACTGCACATCAAAATCTCCGACCTTGGGTTGTCTAGAGAAATCTACTCCTCTGATTATTACAGAGTCCAACCCAACACCCTCCTCCCTATTCGCTGGATGCCACCAGAGGCCATAGTTTATGGGAAATACAGCACAGATTCTGACGTTTGGGCGTTTGGTGTGGTTTTATGGGAGATCTTCAGCTTTGGTTTGCAGCCTTATTATGGCTTCAGCAATCAGGAGGTGATGGAGATGGTACGAAAGAGGCAGCTGTTGCCCTGTCCAGAGGATTGCCCTCCTCGCATGTATGCCCTGATGACTGAGTGTTGGCAAGAAGGTCCTGCTCGCCGGCCGAGATTTAAAGACATCCATACACGTCTACGGGCTTGGGAGGGTCTGTCCTCTCATGCCAGCTCCAGCACACCATCTGGAGGCAACGCCACCACCCAGACTACCTCTCTGAGCGCAAGTCCTGTCAGCAACCTCAGCAGCCCACGCTATGCCGGCTACATCTATGGGGCTCCACAGAGCCTTCAACCTGGACAGATTACAGGCTTCATGGCGGCACCAATGCCACAAAGCCAACGTTTTATACCTGTGAATGGATACCCTATTCCTACGGGATACGCCGCATTTCCTGCTGCCCATTTTGCTGCATCTCAAGGCCCACCACAGGTGGTGCAGCATTGCCCTCCACCCAAAAGCCGGTCGCCCAGTAGTGCCAGCGGCTCCACCAGCACGGGTCACGTGACCAGCGTGCCCTCCACAGGCTCCAATCATGACGCCAACACACCACTGCTTTCTCATTGTGTCACTCTGACGCCCATGACAGCAGTGCCAGGTGGTACACTGCCAGTTTTTGGACATATGGCACAGAAGGCCATGCAAATAGACCCAAGTCAGGCGGCACTGCTGGCTGACACTAACAGACTGATGTACAGCGAATCCATCATCACTGCAGATTTGTGAATACTCGTTTTGTCCTGTacattgataattattgatattttaatGTCTGTTCTTCCTTGTAAATATGAAATAGCCTGAACAGAATGCGaaagtttatattttattgtgtgtttttataaatgtgtcttaAAGGAAACTTGTATATTCACATATTCTCTGTGAAGCTccatgccacttttttttttttataaatgtggcaGAACGGccttaaaatgtgctttttgtcAAACaggatttttacatttatttttcaaggTTATTTTGGACAGAGCTGTGgcttttttgtctcttttttcaCTTATTGATGACTTGAACGCTTCAGACTGTCTCTGTTGTGGCAGTGGCCTTTTGGATGAATTGAACAAGTTAAAATacattaaagcgatagttcacccatttactcaccctccacgtGTGACTTGCCACAAACGGGTTTCTCTAGAATATATTTTGGAAACCCCAAactatttacttccatagtattagcttttcctactatgggagTCAATAATGGCCACAGATTTCTAgaattcttcaaaatgttttcttatgTGCTCAACAATAGACAgacgaactatccctttaatgttgcAGATTCcgaattaaaggaatagttttgcaaatatatatatcaaCCAGGGCCTTGATATAGAAAAACATATTACTTTAATCATGGCCACCATATGTGCCTTTTATTATGAATTCAGGGAGGAAAGTAAAGTTTTGATAAAGTCAGAAGTGTCTGATAAagtcttagtcaaatgatttcaaAGTAAAAGTCATATCAGGGCTGCATCTGAAAGTTTATCTTTCAGAAAAACATTTGCATTTCATCCTGAAAGTGATTTCAGAGAGGCTACGCATtcataaaacatcaaaatatAGAGAATTTTTGATAACTTAGcaaacatttaaacacaagttgacaaaaaatacatacaagTTTATGTGCTGACCCCAACTGGTCAGATGTATTTTCCCTTTCATCTCAAATTGTCTACATATACGCTACATATATGATATTTAAATCAGGATGTTTCATCTAAATGCGTCAACCTTCACGTTACTGTGTGGCAAAGCATATGTGAAAACGGCCCTTTAACTGATGCAGAACTTTTTTTAATATGAACTCCTTACTACCTATAGAATGTAATACCTAACAATTCCTCTAGAGGTCAGTGTCGCTCTTTGACTCTGATTGAATGAAGTTTTTATTTGTCTCTCAATTATACTGTATGTGTCTGCTATTTTTCAATCTTCACTTGATGTTTGATATCTGTCTCCAAGTTTGTAGCTTGTTTAATCTCTTTACGCATCACAGAAATAGGGGTTAAACCAATCGGATCATTTTCGTAAGCAGCTGTATGTCATTTTCATTCTCTTTTTGGTTTGTTGCTATGCAACTGTTTAATTCAAGCGCACTCTTTTCCTGTGATGAAGACAATCAAGAGTTTCTCTTTTATGCAGGGTACAGTGTTTGTGAAGACATGATTGCTTTATGACCTATGAAATGCCTTATGGACAATCTCATGATGCGTCATGACATTTCATGAACAGACATTATG
>TCONS_00063985
tctgtctgtctgtctgtctgtctgtctatctgtctgtccgttcgtccatgcatttatccattatttatctatctgtctatctgtctgtccacctGTCTGTCCGCcagtctgtttgtccatccatccatccatccatccattagtctgtctatatATCACTTCCTAAGGCTGGACGCTCCTATGAATAACATTACTACTTCCCTCGGACAGACAGCTGAGTTGCATTGCCACGTTTCGGGGACTCCATCACCCTCAGTCCGCTGGCTTAAAAACGATGCCCCTGTGGTTCAGGAGCCACGGCGGGTCTCGTACAGACCGACTCCGTACGGCTCGCGCTTGAGAATCAAAAATCTGGACACCACAGACACCGGCTACTTTCAGTGTGTGGCGACCAACAGCTATGGCACAGTGTCAACCACAGGAATCCTGTTTGTCAAGTTTGATCCGGCTCCCACACCTCTGCCTGGACGACCTTCACCaGAGGATTTTGACGAGGAGGGTTTCTGCCAGCCATACAGAGGGATTGCGTGCGCTCGCTTCATAGGAAACAGGAGCATTTTTGTGGACTCGCTGCAGATGCAAGGCGAGATTGAGACCCAAATCACAGcggcATTCACCATGATTGGCACCTCCAATCACCTGTCCGATCGCTGTTCCCAGTTTGCCATCCCATCCCTGTGTCACTTTGCCTTCCCGACATGCGACCGCAGCTCTGGCATGGACAAGCCGCGGGACTTATGTAAAGATGAGTGTGAGATTCTGGAGAATGACCTATGTAAAACTGAGTACATCATCGCTCGATCAAACCCTCTCATTCTTAAACGACTCAAACTGCCTAAATGTGAAGATCTGGCCACTTTGGACAGTCCCGAGGCTGCAAACTGCATGAGGATTGGCATTCCTATAGCGGAGACCATTAATAAAAGTCACAAATGTTACAACAACAGTGGTTCAGACTACCGTGGCACTGTCAGTGTGACTAAATCTGGTCGTCAGTGTCAGCCGTGGAACTCTCAGTATCCCCACAGTCACACCTTCCTGGCCATGCGTTATCCAGAACTCAACGGGGGACATTCCTACTGCCGCAACCCCGGAAACAAGCACGACGCTCCCTGGTGTTTCACCCTCGATGAGGCTGTGCGCATGGAGCTCTGTGACATTCCTCCATGCGATTTGCCCAAGCATGGCAGCAGCAGCAACAGTATGGGAATCCTGTACATCCTGGTACCAAGTGTGGCTATACCACTGGCTATTGCTCTGCTGTTCTTTTTCATCTGTGTTTGTCGAAACAACCAGAAAGCCTCACGTCCACCAGCACCACGTCAGCCCAAACCCGTTCGTGGCCAGAACGTGGAGATGTCCATGCTCACAGCCTACAAACCAAAGAGTAAAGCCAAGGAGCTTCCTCTGTCTGCGGTACGCTTCATGGAGGAGCTGGGCGAGAGTGCCTTCGGTAAGATCTACAAAGGCCACCTGTACCTGCCTGGCATGGAGCACGCTCAACTTGTGGCCATAAAAACCCTGAAGGACATCTCCAGTGCACAACACTGGGGCGATTTCCAGCAGGAAGCATCCGTCTTGGCAGAACTTCACCACCCTAATGTGGTTTGTCTCCTGGGTGTAGTGACCCAAGAGCAGCCCGTCTGCATGCTCTTCGAGTTCCTGGCCCAAGGCGACCTCCACGAGTTCCTCATCATGCGCTCTCCACATTCAGATGTGGGCTGCAGCAGCGACGAAGACGGCACTGTCAAGTCCAGCCTCGACCACGGAGACTTCCTTCACCTGGCCATTCAGGTGGCGGCTGGAATGGAATACCTGGCCAGCCATTTTTTCATCCACAAAGATCTTGCAGCCCGTAACATCCTAGTTGGCGAACAACTGCACATCAAAATCTCCGACCTTGGGTTGTCTAGAGAAATCTACTCCTCTGATTATTACAGAGTCCAACCCAACACCCTCCTCCCTATTCGCTGGATGCCACCAGAGGCCATAGTTTATGGGAAATACAGCACAGATTCTGACGTTTGGGCGTTTGGTGTGGTTTTATGGGAGATCTTCAGCTTTGGTTTGCAGCCTTATTATGGCTTCAGCAATCAGGAGGTGATGGAGATGGTACGAAAGAGGCAGCTGTTGCCCTGTCCAGAGGATTGCCCTCCTCGCATGTATGCCCTGATGACTGAGTGTTGGCAAGAAGGTCCTGCTCGCCGGCCGAGATTTAAAGACATCCATACACGTCTACGGGCTTGGGAGGGTCTGTCCTCTCATGCCAGCTCCAGCACACCATCTGGAGGCAACGCCACCACCCAGACTACCTCTCTGAGCGCAAGTCCTGTCAGCAACCTCAGCAGCCCACGCTATGCCGGCTACATCTATGGGGCTCCACAGAGCCTTCAACCTGGACAGATTACAGGCTTCATGGCGGCACCAATGCCACAAAGCCAACGTTTTATACCTGTGAATGGATACCCTATTCCTACGGGATACGCCGCATTTCCTGCTGCCCATTTTGCTGCATCTCAAGGCCCACCACAGGTGGTGCAGCATTGCCCTCCACCCAAAAGCCGGTCGCCCAGTAGTGCCAGCGGCTCCACCAGCACGGGTCACGTGACCAGCGTGCCCTCCACAGGCTCCAATCATGACGCCAACACACCACTGCTTTCTCATTGTGTCACTCTGACGCCCATGACAGCAGTGCCAGGTGGTACACTGCCAGTTTTTGGACATATGGCACAGAAGGCCATGCAAATAGACCCAAGTCAGGCGGCACTGCTGGCTGACACTAACAGACTGATGTACAGCGAATCCATCATCACTGCAGATTTGTGA

Function


symbol description
ror1 Predicted to enable Wnt-protein binding activity. Predicted to be involved in positive regulation of intracellular signal transduction; positive regulation of kinase activity; and positive regulation of neuron projection development. Predicted to act upstream of or within protein phosphorylation and transmembrane receptor protein tyrosine kinase signaling pathway. Predicted to be located in plasma membrane. Predicted to be integral component of membrane. Predicted to be part of receptor complex. Predicted to be integral component of plasma membrane. Is expressed in gonad. Human ortholog(s) of this gene implicated in autosomal recessive nonsyndromic deafness 108. Orthologous to human ROR1 (receptor tyrosine kinase like orphan receptor 1).

GO:

id name namespace
GO:0033674 positive regulation of kinase activity biological_process
GO:0007275 multicellular organism development biological_process
GO:0010976 positive regulation of neuron projection development biological_process
GO:0043408 regulation of MAPK cascade biological_process
GO:0043410 positive regulation of MAPK cascade biological_process
GO:0006468 protein phosphorylation biological_process
GO:0043123 positive regulation of I-kappaB kinase/NF-kappaB signaling biological_process
GO:0007399 nervous system development biological_process
GO:0014068 positive regulation of phosphatidylinositol 3-kinase signaling biological_process
GO:0007169 transmembrane receptor protein tyrosine kinase signaling pathway biological_process
GO:0005887 integral component of plasma membrane cellular_component
GO:0016020 membrane cellular_component
GO:0016021 integral component of membrane cellular_component
GO:0043235 receptor complex cellular_component
GO:0005524 ATP binding molecular_function
GO:0017147 Wnt-protein binding molecular_function
GO:0000166 nucleotide binding molecular_function
GO:0004672 protein kinase activity molecular_function

KEGG:

id description
ko04310 Wnt signaling pathway
ko01001 Protein kinases

ZFIN:

id description
ZDB-GENE-030131-6104 Predicted to enable Wnt-protein binding activity. Predicted to be involved in positive regulation of intracellular signal transduction; positive regulation of kinase activity; and positive regulation of neuron projection development. Predicted to act upstream of or within protein phosphorylation and transmembrane receptor protein tyrosine kinase signaling pathway. Predicted to be located in plasma membrane. Predicted to be integral component of membrane. Predicted to be part of receptor complex. Predicted to be integral component of plasma membrane. Is expressed in gonad. Human ortholog(s) of this gene implicated in autosomal recessive nonsyndromic deafness 108. Orthologous to human ROR1 (receptor tyrosine kinase like orphan receptor 1).

Ensembl:

ensembl_id ENSDARG00000015176

RNA


RNA id representative length rna type GC content exon number start site end site
TCONS_00063984 False 4562 mRNA 0.47 9 31772182 31987940
TCONS_00063985 True 2826 mRNA 0.53 8 31773747 31827597

Neighbor


gene id symbol gene type direction distance location
XLOC_032933 NA coding downstream 22398 31745291 ~ 31749784 (-)
XLOC_032932 cachd1 coding downstream 32473 31590751 ~ 31739709 (-)
XLOC_032931 raver2 coding downstream 195785 31430791 ~ 31576397 (-)
XLOC_032930 ak4 coding downstream 407631 31350101 ~ 31364551 (-)
XLOC_032929 dnajc6 coding downstream 423183 31279542 ~ 31348999 (-)
XLOC_032936 pgm1 coding upstream 22243 32010183 ~ 32025225 (-)
XLOC_032937 efcab7 coding upstream 41291 32029231 ~ 32045983 (-)
XLOC_032938 alg6 coding upstream 77154 32065094 ~ 32087111 (-)
XLOC_032939 foxd3 coding upstream 104092 32092032 ~ 32093830 (-)
XLOC_032940 NA coding upstream 207868 32195808 ~ 32196825 (-)
XLOC_032927 CR847887.1 non-coding downstream 624927 31069530 ~ 31147255 (-)
XLOC_032920 NA non-coding downstream 1313167 30452287 ~ 30459015 (-)
XLOC_032919 FP236850.1 non-coding downstream 1550212 30221834 ~ 30221970 (-)
XLOC_032918 FP236850.2 non-coding downstream 1569145 30202921 ~ 30203037 (-)
XLOC_032944 NA non-coding upstream 427136 32415076 ~ 32416753 (-)
XLOC_032945 LO017955.2 non-coding upstream 586056 32573996 ~ 32592792 (-)
XLOC_032946 NA non-coding upstream 699062 32687002 ~ 32687386 (-)
XLOC_032952 NA non-coding upstream 1202642 33190582 ~ 33210388 (-)

Expression



Co-expression Network


Homologous


species gene id symbol gene type chromosome NCBI id location
bowfin (Amia calva) AMCG00005223 NA coding CM030140.1 CM030140.1 19219826 ~ 19226999 (-)