XLOC_032942 (angptl3)


Basic Information

Item Value
gene id XLOC_032942
gene name angptl3
gene type coding
species zebrafish (Danio rerio)
category of species model fish

Chromosome Information

Item Value
chromosome id NC_007117.7
NCBI id CM002890.2
chromosome length 60270059
location 32344197 ~ 32349153 (-)
genome version GRCz11_2017_zebrafish_Genome

Sequence

>TCONS_00063999
GCGTTCAAGTATGAGATGAGAAGCGAGAAAAGAGGCTTGAAAGAGACCCAGCAGGGAACAGACTGAAGCAGTGAGCAAATCTACTTTTAAACCAACAAAAAGGATGTTGATGTTGATCCTGCTTTTGTGGCTAAGCTTGTCCACAACAAGCGCAGCCCCTAACTCAAAGAAATCACCCACGGAGGCGCCAATACTTATAACCGCACCGCCGACTGAAGCTAGATCCCGCTTCGCCATGCTAGATGACGTGCGACTGCTGGCCAACGGTCTGCTTCAGCTCGGCCAGAGTCTCAGAGAGTTTGTGCACAAGACCAAGTCTCAGATCAACGACATCTTCCAGAAGCTCAACATCTTTGATCGTTCCTTCTACCAGCTCTCGGTGGTCACCAGCGAAATtaaagaagaggaggagaagcTGAAGGAGACCACAATATTTTTGAAGGCCAATAATGAGGAGATCAGAAACCTGTCATTGGAGATCAACTCAAAAATCAACAACATTCTCCAAGAGCGCAGCCAGTTGCACACTAAGGTCGGTGGGCTGGAGGAGAAGCTGAAGGGCTTGTCGCAGAGCATGATGCCTTTGGAGCAACTTCAAGAGATCACTGCTTTGAAGGATGTGATTGAAACACAAGAAAGGACCATTACAGATCTGCTTAGATCTGTTAAAGAGCAACATGACCAGCTTAACTACCAGAAGATCAAAATTAAAAGTCTTGAAGATAAGGTCAACTATGACACTTTTCAAGACACCATTGAAAAACCTATGGATTTAAACCCAGAAACCCCCGACCCTTTTCGGTACTTAACAACGAACTCAACAAATGGAACTAAGGATATAAATGATTTTCCAGCAGACTGCAGTGAGGTGTTCACAAGAGGCCAGAAAACCAGTGGAATTTACCCAATCAAGCCCAATCAATCTGAGCCTTTCTATGTTTACTGTGAGATAACCCCTGACGGTGCAGCCACTGTCATCCAGAGGAGGGAGGATGGTTCGGTTGATTTTGACCAGTCATGGGAAAAATATGAACATGGATTTGGGAAACTAGAAAAGGAGTTCTGGCTTGGCTTAGCAAAGATCCATTCCATTGCTCAACAAGGCGAATACATTTTACACATTGAACTGGAGGACTGGAAGGAGGAAAAGAGATTCATCGAGTACACCTTCACGTTGGAAGGCCCTGCATCTGACTATGCCCTTCACTTGGCCCCTTTGTCTGGAGATTTATCCGACGCCATGAGCAACCACACAGGCATGAAGTTCTCAACCAAGGACAGAGACAACGATAATCATGACGAGTCCAACTGTGCCCGCAACTACACAGGTGGTTGGTGGTTTGATGCATGTGGAGACACCAACTTAAATGGAAGATATGCCTGGATGAGATCCAAGGCTCGTCACCAGCGCAGGAAAGGAATCTACTGGAGGCCATCCAAAGGAAGCTCATATACCCTCAAATCCACAAAGATCACCATCAGACCATCAACCCAATTTCAATAATCCCTGACCCTAGACTCTCCATTGGGAAATTCAAAATCAATCAGTGAGGTCACACTGTCAGCAGACACCTGGCCAACAAAACGTTTCCCTTTCTCTAAAGACAGCCGAAACTGGATGATGCAATGGAACTGCAACAGGTCATTGACTCTGGAAGAGGTTAAAAACCAAGTCAAAGGGTTATTGCAACACGCACGCATGCGTTAGTTAGTCAGATTAGAAATTAGTAGCTTGTTGATCAAGAAGTACTAAGACTGAACAGATTCAAATGACAAATCACACCTTTGGAACAGAATCTGGTGCATGTTATTATAGCAATATGTAAATCTGCAGTTTGCAGACCATATGCATATTATTACAGAGCTACACTATATTCAACTATACAGCTTATAAATGTCATTTCACATTGCATGTTAACTTAAAGACAATGTGCAACAGTAGAAAAGCAAAGGATAACACTTTGTAATAAGTTTCATTACATCATAACTGTCATGCTTtaacacactttatattattttaaatacaaaaactaaatatatgcatttttcagtcacactttattttgatagtctgtttgttgaatttaagttacattgcatctacatgccaactaattctcattagattataagtagactgttggggttagtgtaagttgacatgtacttgcaatgtttcttatagtcagttaaatgtctgctgaagaagcagtatcaacagatattaagcagacaatctactaatactcaaatggactatcacaataaagtgttaccaatttttcGTTTTCTATTGAAAGTTAATATAATTGAAGGTTATtacaaagtgttaccaaaaaatgtGGTGTTATAGTTGGGTCTTCTGCATGTCTCTTTCTGTTACTGAGTCATATTGACTCCTGGTTACGCTTTGTACATACTCAGCtctactgtatatatttagttTACAGAATGTTTCTCAGTGGTGTGGGGGTACAACATATTTATAGTGACaataagccaaaaaaataaaaaataaataaatcctttaAATAAGCGG

Function

symbol description
angptl3 Predicted to enable signaling receptor binding activity. Acts upstream of or within hepatocyte proliferation and lipid metabolic process. Predicted to be active in collagen-containing extracellular matrix and extracellular space. Is expressed in liver; liver primordium; and yolk syncytial layer. Human ortholog(s) of this gene implicated in familial hypobetalipoproteinemia 2. Orthologous to human ANGPTL3 (angiopoietin like 3).

GO:

id name namespace
GO:0006629 lipid metabolic process biological_process
GO:0070328 triglyceride homeostasis biological_process
GO:0009395 phospholipid catabolic process biological_process
GO:0055091 phospholipid homeostasis biological_process
GO:0001889 liver development biological_process
GO:0010519 negative regulation of phospholipase activity biological_process
GO:0042632 cholesterol homeostasis biological_process
GO:0072574 hepatocyte proliferation biological_process
GO:0062023 collagen-containing extracellular matrix cellular_component
GO:0005615 extracellular space cellular_component
GO:0005102 signaling receptor binding molecular_function

KEGG:

id description
ko04979 Cholesterol metabolism

ZFIN:

id description
ZDB-GENE-010817-3 Predicted to enable signaling receptor binding activity. Acts upstream of or within hepatocyte proliferation and lipid metabolic process. Predicted to be active in collagen-containing extracellular matrix and extracellular space. Is expressed in liver; liver primordium; and yolk syncytial layer. Human ortholog(s) of this gene implicated in familial hypobetalipoproteinemia 2. Orthologous to human ANGPTL3 (angiopoietin like 3).

Ensembl:

ensembl_id ENSDARG00000044365

RNA

RNA id representative length rna type GC content exon number start site end site
TCONS_00063999 True 2539 mRNA 0.41 7 32344197 32349153

Neighbor

gene id symbol gene type direction distance location
XLOC_032941 atg4c coding downstream 28703 32300018 ~ 32315494 (-)
XLOC_032940 NA coding downstream 147372 32195808 ~ 32196825 (-)
XLOC_032939 foxd3 coding downstream 250367 32092032 ~ 32093830 (-)
XLOC_032938 alg6 coding downstream 257086 32065094 ~ 32087111 (-)
XLOC_032937 efcab7 coding downstream 298214 32029231 ~ 32045983 (-)
XLOC_032943 usp1 coding upstream 45349 32394502 ~ 32411727 (-)
XLOC_032944 NA coding upstream 65923 32415076 ~ 32416753 (-)
XLOC_032945 LO017955.2 coding upstream 224843 32573996 ~ 32592792 (-)
XLOC_032946 NA coding upstream 337849 32687002 ~ 32687386 (-)
XLOC_032947 mafaa coding upstream 350206 32699359 ~ 32703317 (-)
XLOC_032933 NA non-coding downstream 594413 31745291 ~ 31749784 (-)
XLOC_032927 CR847887.1 non-coding downstream 1196942 31069530 ~ 31147255 (-)
XLOC_032920 NA non-coding downstream 1885182 30452287 ~ 30459015 (-)
XLOC_032919 FP236850.1 non-coding downstream 2122227 30221834 ~ 30221970 (-)
XLOC_032952 NA non-coding upstream 841429 33190582 ~ 33210388 (-)
XLOC_032953 CR933860.1 non-coding upstream 1094181 33443334 ~ 33443455 (-)

Expression


Co-expression Network