XLOC_032994 (cth)


Basic Information

Item Value
gene id XLOC_032994
gene name cth
gene type coding
species zebrafish (Danio rerio)
category of species model fish

Chromosome Information

Item Value
chromosome id NC_007117.7
NCBI id CM002890.2
chromosome length 60270059
location 37409558 ~ 37422841 (-)
genome version GRCz11_2017_zebrafish_Genome

Sequence

>TCONS_00064109
TGCGATCTCAGGGATCCGGTATATCACCCTTCACCGTCATATCAGGAGCACTCATGTCTTCAGAGATGCAGAACGACAGCTCAGCCGGCTTCCTGCCGATCTACAAGTCATTCGCTACAGATGCGATCCACGTTGGTTCAGAGCCCGAGCAGTGGAGCTCTATGGCCGTAGTGCCTCCTATTTCACTGTCCACCACCTTTAAACAGCACGGCCCCGGAAAACATGCGGGGTTCGAGTACAGCAGGAGTGGAAATCCGACAAGAAACTGTCTTGAAAAAGCAGTCGCTGCTTTGGATGGTGCAAAATACTGTCTGGCTGTTGCCTCTGGATTGGCGGCAACTTTGACCATCACACATCTTTTTAAAAGTGGAGATGGAATTTTGTGCATGAATGATGTATATGGAGGAACCAACCGATATTTCAGAAAAGTAGCTTCAGAAGTTGGGCTTGATATATCTTTTGCAGACCTCACAAAGCTTGAGGAGTTAAAAGCAGGGCTAAAACCAAATACAAAGATGGTTTGGATTGAAACACCCACAAACCCTACAATGAAGGTTGTGGACATCCAGGCCTGTGCAGATATTGTCCATAAGCACAACAAGGACACAATCGTTGTTGTGGACAACACTTTCATGTCAGCCTACTTCCAGCGCCCCCTTGCACTTGGAGCAGACATCTGCATGTACTCTGCAACAAAATACATGAATGGTCACAGCGATGTCGTCATGGGCCTGATTTCTCTCAGCCGTGACGACCTCTATGAGCGACTGAAATTTTTGCAGAATtCTCTTGGTGCTGTGCCGTCTCCATTTGACTGTTACATGTGCAATCGGGGTCTGAAGACGCTGCACCTGAGGATGAAGCAGCACTTTAAGAACGCACTGGCTGCAGCACAGTTTCTAGAGGCCGACCCGAGGGTGGACAGAGTCATCTTCCCAGGTCTTCCGTCTCATCCTCAACATGAGCTAACAAAGAGACAGTGCACGGGCTGTCCTGGGATGATCACATTTTACATcaaagggaaactggagcatgcTTCAACCTTCCTCAGCAATCTAAAGTTGTTTGCACTTGCTGAAAGTCTTGGGGGTTATGAGAGTCTAGCAGAACACCCAGCGATTATGACTCATGCTTCGGTGTGCGAGGAAGAGAGGAAGAAGCTGGGCATCAGTGATACACTCATTCGTCTTTCAGTGGGTCTGGAGGACGAGGAAGATATTATTGCAGATCTGGACCAAGCTCTCGGTGCTGCAcatcCAAAGAAGTGAAAGACGGATGAGGAACAGCAGTGATGCCACACGTGGATGAGATGAGGACACTTTTATGTGGCACATTAGTGATTTACTTTGTATATTATGCTTACTTGAAAAACATCAGTTGCATTTGTCAGGGAACAACTGTCCTCTAGAAAACTTGTTTGCCATGTTTTAATATAAAGGAGATTTGGTGCTTTTGTGTTTCTACTTTTTGTAATTGAAGTTTGATGAGGTAATGTGCAGCCAAACAAAACCGCACATACAAGTTTTGATGAAAGGAAAGTGGCAGGAATGCAAGGGAAATCTAAACAAAATCTATGATTTAGATAGACTGTACAAGTTATTCAAAAACTGCAACATGCACAAAAGACACCATCAGTGTTTTCAGGTAgtgagcagtttttattttctgcaTCAAAATCACCTCATTATGTTCCAATCACCCTTCACCGAACAGCCGAATTTTAAATACTTGACAATAATGAGATGCTTGAGCGTTTTCAATTCTAAAGGGATCACTTCAGATCTTTGTCTGTGTTACCAGACCCATTAAAAGCCATTTGTAGTCTCCA

Function

symbol description
cth Predicted to enable cystathionine gamma-lyase activity and pyridoxal phosphate binding activity. Predicted to be involved in cysteine biosynthetic process via cystathionine and transsulfuration. Predicted to act upstream of or within cysteine biosynthetic process. Predicted to be active in cytoplasm. Human ortholog(s) of this gene implicated in amino acid metabolic disorder and cystathioninuria. Orthologous to human CTH (cystathionine gamma-lyase).

GO:

id name namespace
GO:0019343 cysteine biosynthetic process via cystathionine biological_process
GO:0019346 transsulfuration biological_process
GO:0005737 cytoplasm cellular_component
GO:0030170 pyridoxal phosphate binding molecular_function
GO:0016829 lyase activity molecular_function
GO:0016846 carbon-sulfur lyase activity molecular_function
GO:0003824 catalytic activity molecular_function
GO:0004123 cystathionine gamma-lyase activity molecular_function

KEGG:

id description
ko00260 Glycine, serine and threonine metabolism
ko00270 Cysteine and methionine metabolism
ko00450 Selenocompound metabolism
ko04147 Exosome

ZFIN:

id description
ZDB-GENE-030131-774 Predicted to enable cystathionine gamma-lyase activity and pyridoxal phosphate binding activity. Predicted to be involved in cysteine biosynthetic process via cystathionine and transsulfuration. Predicted to act upstream of or within cysteine biosynthetic process. Predicted to be active in cytoplasm. Human ortholog(s) of this gene implicated in amino acid metabolic disorder and cystathioninuria. Orthologous to human CTH (cystathionine gamma-lyase).

Ensembl:

ensembl_id ENSDARG00000074301

RNA

RNA id representative length rna type GC content exon number start site end site
TCONS_00064109 True 1828 mRNA 0.45 12 37409558 37422841
Loading

Neighbor

gene id symbol gene type direction distance location
XLOC_032993 cthl coding downstream 6114 37389683 ~ 37403444 (-)
XLOC_032992 NA coding downstream 64964 37342328 ~ 37344594 (-)
XLOC_032988 opa1 coding downstream 614339 36717985 ~ 36795219 (-)
XLOC_032995 nit2 coding upstream 8328 37431169 ~ 37441520 (-)
XLOC_032996 BX324166.2 coding upstream 16414 37439255 ~ 37439370 (-)
XLOC_032997 BX324166.3 coding upstream 24187 37447028 ~ 37447143 (-)
XLOC_032998 si:dkey-66a8.7 coding upstream 28500 37451341 ~ 37460178 (-)
XLOC_032999 plcxd1 coding upstream 37428 37460269 ~ 37469775 (-)
XLOC_032991 CT033823.2 non-coding downstream 639489 36769939 ~ 36770069 (-)
XLOC_032990 CT033823.3 non-coding downstream 665307 36744134 ~ 36744251 (-)
XLOC_032989 CT033823.1 non-coding downstream 675732 36733709 ~ 36733826 (-)
XLOC_032987 NA non-coding downstream 781461 36621310 ~ 36628097 (-)
XLOC_033003 BX322552.1 non-coding upstream 192525 37615366 ~ 37615483 (-)
XLOC_033006 CR407584.1 non-coding upstream 709670 38132511 ~ 38358080 (-)
XLOC_033008 CR628341.2 non-coding upstream 1174828 38597669 ~ 38597784 (-)

Expression

Expression of XLOC_032994(cth) in the Zebrafish Sample from each Developmental Stage of PRJEB12982

Boxplot with 18 boxes. Box plot charts are typically used to display groups of statistical data. Each data point in the chart can have up to 5 values: minimum, lower quartile, median, upper quartile, and maximum.
The chart has 1 X axis displaying categories.
The chart has 1 Y axis displaying Expression. Range: 0 to 150.
End of interactive chart.

Expression of XLOC_032994(cth) in the Zebrafish Sample of PRJEB12982

Bar chart with 360 bars.
The chart has 1 X axis displaying categories.
The chart has 1 Y axis displaying Expression. Range: 0 to 150.
End of interactive chart.

Co-expression Network

Homologous

species gene id symbol gene type chromosome NCBI id location
grasscarp (Ctenopharyngodon idella) CI01000340_07994499_07999442 CTH, CGL coding CI01000340 null 7994499 ~ 7999651 (-)